Abstract: Adeno associated viral (AAV) particles are emerging as a useful vehicle for gene delivery to various organs and tissues, one of them being the retina. Provided here are variant AAV (e.g., variant serotype 2 (AAV2)) capsid proteins and variant capsid protein containing particles with enhanced ability to transduce retinal cells.

Abstract: microRNAs and compositions comprising same for the treatment and diagnosis of serotonin-, adrenalin-, noradrenalin-, glutamate-, and corticotropin-releasing hormone-associated medical conditions are provided.

Abstract: An annular fluidic device includes a closed annular tube, wherein the tube includes at least one portion of transparent wall and contains a rigid torus bathed in a fluid filling the internal volume of the tube, in that the torus is arranged to be movable in the tube, and wherein at least one permanently polarised magnetic element integral with the torus allows it to undergo a moment of force causing it to be aligned in the direction of the external magnetic vector. A watch case can include this device.

Abstract: A method for depositing a rare material in a thin layer at the surface of an horological or jewellery external part includes providing a rough part of rare material, shaping the rough part of rare material so that it is adapted to be used as a target part for a PVD method, depositing material of the target part at the surface of a substrate consisting of an horological or jewellery eternal part by a PVD method so as to cover the external part.

Abstract: The disclosure relates to a method and device for inputting and outputting packets inside a GPU based on a commodity Ethernet device. According to embodiments of the disclosure, a method for commodity Ethernet device-based graphic processing unit (GPU) internal packet input/output performed by a GPU internal packet input/output device comprises being allocated an available packet buffer from a memory pool inside a GPU, after packets received from a network interface controller (NIC) are directly transferred to the allocated packet buffer, processing the directly transferred packets through a reception (Rx) kernel, transmitting a transmission packet to a network through the NIC according to an operation of a transmission (Tx) kernel, and returning the allocated packet buffer.

Abstract: In various embodiments compounds that induce and/or promote autophagy are provided as wells as methods of use thereof (e.g., in the prophylaxis or treatment of chronic pathologies associated with aging). In one illustrative, but non-limiting embodiments the compound(s) comprise, inter alia, coumarin 106.

Abstract: The present invention relates to RNA interference-inducing nucleic acid that inhibits noncanonical target genes of micro RNA, in which part of the sequence of a specific micro RNA has been modified, and by using the RNA interference-inducing nucleic acid of the present invention, the biological function micro RNA exhibits by inhibiting noncanonical target genes is effectively increased or there is the benefit of selectively exhibiting only one of the biological functions of conventional micro RNA, i.e., the function of inhibiting noncanonical target genes, and the interference-inducing nucleic acid of the present invention enables cell cycling, differentiation, dedifferentiation, formation, movement, splitting, proliferation or death adjustment, and it is expected that the invention can be used in various fields such as drugs and cosmetics.

Abstract: A method of treating or preventing a sickle cell disease in a subject in need thereof is disclosed. The method comprising: (a) transplanting immature hematopoietic cells into the subject; and (b) administering to the subject a therapeutically effective amount of an isolated population of non-GVHD inducing anti-third party cells comprising cells having a central memory T-lymphocyte (Tcm) phenotype, the cells being tolerance inducing cells and capable of homing to the lymph nodes following transplantation.

Abstract: A drop-on-demand (DOD) printer is disclosed having an ejector which may include a nozzle, the nozzle including a tank in communication with a source of printing material, a constricted dissipative section in communication with the tank, which may include an elongated internal channel, and a shaping tip in communication with the constricted dissipative section which can include an exit orifice. The (DOD) printer also includes a power source configured to supply one or more pulses of power to the ejector, which causes one or more drops of the printing material to be jetted out of the nozzle. The DOD printer may include a constricted dissipative section configured to obstruct fluid flow that is cylindrical or axisymmetric and having a diameter less than a diameter of the tank and less than a diameter of the shaping tip. The DOD printer may include a nozzle or an array of nozzles.

Abstract: This disclosure provides methods for enhancing antitumor cytotoxicity of immune cells by introducing to the immune cells a genetic modification that comprises overexpression of RHEB or a functional fragment thereof, overexpression of LAMP 1-RHEB or a functional fragment thereof, overexpression of CA9 or a functional fragment thereof, overexpression of NHE1 or a functional fragment thereof, or combination thereof.

Abstract: A semiconductor memory device capable of improving performance by the use of a charge storage layer including a ferroelectric material is provided. The semiconductor memory device includes a substrate, a tunnel insulating layer contacting the substrate, on the substrate, a charge storage layer contacting the tunnel insulating layer and including a ferroelectric material, on the tunnel insulating layer, a barrier insulating layer contacting the charge storage layer, on the charge storage layer, and a gate electrode contacting the barrier insulating layer, on the barrier insulating layer.

Abstract: Provided herein are methods and compositions for a suicide gene approach comprising an expression vector comprising a cell cycle-dependent promoter driving the expression of a suicide gene. Also provided herein are methods to render proliferative cells sensitive to a prodrug after transplantation but avoids expression of the suicide gene in post-mitotic cells, such as neurons.

Abstract: The present invention relates to methods of predicting endometrial receptivity for embryo implantation in a subject, the method comprising determining a level of podocalyxin in endometrial epithelial cells in the subject. The present invention also relates to methods of monitoring epithelial receptivity and improving epithelial receptivity.

Abstract: A method of treating or preventing a T cell mediated autoimmune disease in a subject in need thereof is disclosed. The method comprising: (a) transplanting immature hematopoietic cells into the subject; and (b) administering to the subject a therapeutically effective amount of an isolated population of non-GVHD inducing anti-third party cells comprising cells having a central memory T-lymphocyte (Tcm) phenotype, the cells being tolerance inducing cells and capable of homing to the lymph nodes following transplantation.

Abstract: A GAPDH nucleic acid detection kit includes a primer set for detecting GAPDH nucleic acid. The primer set for detecting GAPDH nucleic acid includes a forward inner primer for GAPDH nucleic acids, a forward outer primer for GAPDH nucleic acids, a backward inner primer for GAPDH nucleic acids and a backward outer primer for GAPDH nucleic acids. The primer set for detecting GAPDH nucleic acid is used in a loop-mediated isothermal amplification (LAMP).

Abstract: Device assisted services (DAS) install techniques are provided in accordance with some embodiments. In some embodiments, DAS install techniques for providing service processors for mobile devices are provided. In some embodiments, DAS install techniques for downloading/installing new and/or updated service processors for mobile devices are provided. In some embodiments, DAS install techniques for providing verified service processors for mobile devices are provided. In some embodiments, DAS install techniques for providing secured service processors for mobile devices are provided.

Abstract: A radiocommunication device, configured to implement a communication method, including an antenna for picking up at least one set of electromagnetic waves and/or for radiating at least one first group of data and/or at least one second group of data. The device further includes at least one first radiocommunication circuit, configured to receive at least one set of electromagnetic waves and/or to transmit at least one first group of data, and at least one second radiocommunication circuit, configured to receive at least one set of electromagnetic waves and/or to transmit at least one second group of data.

Abstract: A method for analyzing dementia severity, may comprise calculating color data from skin regions of interest of a frontal lobe region; calculating frequency values corresponding to a frequency band of a dementia-related biosignal based on the calculated color data; and analyzing dementia severity using the calculated frequency values.

Abstract: Disclosed herein is a method for generating a depth map from multi-view images, the method including receiving multi-view images and parameters thereof; generating an initial depth map, an initial normal map, and an initial reliability map for the multi-view images; performing selection of multiple initial vertices and triangulation based on the initial depth map and the initial normal map and generating depth values and normal values for the result of triangulation; performing regularization based on triangulation, selecting additional vertices in the initial depth map, and generating additional depth values and additional normal values based on the additional vertices and regularization; and refining the initial depth map into a refined depth map by replacing depth values and normal values having reliability below a preset level in the initial depth map and the initial normal map with the additional depth values and the additional normal values.

Abstract: A nozzle for a printing system is disclosed. The nozzle includes a tank in communication with a source of printing material. The nozzle also includes a constricted dissipative section in communication with the tank, which may include an elongated internal channel. The nozzle may also include a shaping tip in communication with the constricted dissipative section may include an exit orifice. The constricted dissipative section may be axisymmetric and may include at least three internal channels not in communication with one another. Also disclosed is an array of nozzles for a printing system including a plurality of nozzles, with each nozzle including a tank in communication with a source of printing material, a constricted dissipative section in communication with the tank and configured to obstruct fluid flow and having an elongated internal channel, and a shaping tip in communication with the constricted dissipative section may include an exit orifice.