Abstract: A system for a wavefront imaging sensor with high resolution (WISH) comprises a spatial light modulator (SLM), a plurality of image sensors and a processor. The system further includes the SLM and a computational post-processing algorithm for recovering an incident wavefront with a high spatial resolution and a fine phase estimation. In addition, the image sensors work both in a visible electromagnetic (EM) spectrum and outside the visible EM spectrum.

Abstract: In one aspect, the present disclosure provides tubulysin analogs of the formula (I) wherein R1, R2, R3, R4, X1, X2, X3, and A1 are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein.

Abstract: The present disclosure provides methods, composition and devices for performing convection-based PCR and non-enzymatic amplification of nucleic acid sequences. Techniques and reagents employed in these methods include toehold probes, strand displacement reactions, Rayleigh-Benard convection, temperature gradients, multiplexed amplification, multiplexed detection, and DNA functionalization, in open and closed systems, for use in nucleic tests and assays.

Abstract: Methods to create two component signal transduction systems by replace the DNA binding domains and output promoters in bacteria are described.

Abstract: The present disclosure describes an engineered microorganism for producing alpha omega bifunctional C6-16 fatty acids from renewable carbon sources.

Abstract: An energy storage device including a first electrode comprising lithium, a second electrode comprising a metal diboride, an electrolyte disposed between the first electrode and the second electrode and providing a conductive pathway for lithium ions to move to and from the first electrode and the second electrode, and a separator within the electrolyte and between the first electrode and the second electrode. A method of forming an energy storage device including forming a first electrode to include lithium, forming a second electrode to include a metal diboride, disposing an electrolyte between the first electrode and the second electrode, the electrolyte providing a conductive pathway for lithium ions to move to and from the first electrode and the second electrode, and disposing a separator within the electrolyte and between the first electrode and the second electrode.

Abstract: A multicomponent photocatalyst includes a reactive component optically, electronically, or thermally coupled to a plasmonic material. A method of performing a catalytic reaction includes loading a multicomponent photocatalyst including a reactive component optically, electronically, or thermally coupled to a plasmonic material into a reaction chamber, introducing molecular reactants into the reaction chamber, and illuminating the reaction chamber with a light source.

Abstract: Microbes and methods used to convert renewable carbon sources such as glucose, sucrose, biomass hydrolysate, methanol or formate, to succinate-derived products, such as fumarate or malate, which are desirable products having many uses.

Abstract: In one aspect, embodiments disclosed herein relate to a lens-free imaging system. The lens-free imaging system includes: an image sampler, a radiation source, a mask disposed between the image sampler and a scene, and an image sampler processor. The image sampler processor obtains signals from the image sampler that is exposed, through the mask, to radiation scattered by the scene which is illuminated by the radiation source. The image sampler processor then estimates an image of the scene based on the signals from the image sampler, processed using a transfer function that relates the signals and the scene.

Abstract: A method of making a multicomponent photocatalyst, includes inducing precipitation from a pre-cursor solution comprising a pre-cursor of a plasmonic material and a pre-cursor of a reactive component to form co-precipitated particles; collecting the co-precipitated particles; and annealing the co-precipitated particles to form the multicomponent photocatalyst comprising a reactive component optically, thermally, or electronically coupled to a plasmonic material.

Abstract: Embodiments of the present disclosure pertain to methods of making a carbon nanotube hybrid material by depositing a catalyst solution onto a carbon-based material, and growing carbon nanotubes on the carbon-based material such that the grown carbon nanotubes become covalently linked to the carbon-based material through carbon-carbon bonds. The catalyst solution includes a metal component (e.g., iron) and a buffer component (e.g., aluminum) that may be in the form of particles. The metal component of the particle may be in the form of a metallic core or metallic oxide core while the buffer component may be on a surface of the metal component in the form of metal or metal oxides. Further embodiments of the present disclosure pertain to the catalytic particles and carbon nanotube hybrid materials. The carbon nanotube hybrid materials of the present disclosure may be incorporated as electrodes (e.g., anodes or cathodes) in energy storage devices.

Abstract: A method for imaging objects includes illuminating an object with a light source of an imaging device, and receiving an illumination field reflected by the object. An aperture field that intercepts a pupil of the imaging device is an optical propagation of the illumination field at an aperture plane. The method includes receiving a portion of the aperture field onto a camera sensor, and receiving a sensor field of optical intensity. The method also includes iteratively centering the camera focus along the Fourier plane at different locations to produce a series of sensor fields and stitching together the sensor fields in the Fourier domain to generate an image. The method also includes determining a plurality of phase information for each sensor field in the series of sensor fields, applying the plurality of phase information to the image, receiving a plurality of illumination fields reflected by the object, and denoising the intensity of plurality of illumination fields using Fourier ptychography.

Abstract: A nanosample capable of near-infrared light-triggered release of therapeutic molecules. The nanosample includes a plurality of nanocomplexes. Each of the nanocomplexes includes a nanoshell; a host molecule linked to the nanoshell; and a guest molecule linked to the host molecule. The nanoshell includes a shell. The nanocomplex has a plasmon resonance wavelength. When irradiated with electromagnetic radiation of the plasmon resonance wavelength, plasmon resonance of the nanocomplex releases the guest molecule. The nanoshell may also include a core, where the shell surrounds the core. The nanoshell may be a nanomatryoshka. A link between the nanoshell and the host molecule may be a gold-thiol interaction. The shell may include at least one metal, such as gold or silver. The core may be a liposome and/or silica. The host molecule may be: synthetic polymers, biopolymers, polynucleotides, nucleic acids, polypeptides, polysaccharides, polyterpenes, lipids, aptamers, and/or proteins.

Abstract: The invention relates to recombinant microorganisms that have been engineered to produce various chemicals using genes that have been repurposed to create a reverse beta oxidation pathway. Generally speaking, the beta oxidation cycle is expressed and driven in reverse by modifying various regulation points for as many cycles as needed, and then the CoA thioester intermediates are converted to useful products by the action of termination enzymes.

Abstract: In some embodiments, the present disclosure pertains to methods of producing a graphene material by exposing a polymer to a laser source. In some embodiments, the exposing results in formation of a graphene from the polymer. In some embodiments, the methods of the present disclosure also include a step of separating the formed graphene from the polymer to form an isolated graphene. In some embodiments, the methods of the present disclosure also include a step of incorporating the graphene material or the isolated graphene into an electronic device, such as an energy storage device. In some embodiments, the graphene is utilized as at least one of an electrode, current collector or additive in the electronic device. Additional embodiments of the present disclosure pertain to the graphene materials, isolated graphenes, and electronic devices that are formed by the methods of the present disclosure.

Abstract: A method of forming an electrode for capacitive deionization includes depositing an slurry onto a substrate, wherein the slurry comprises a porous material, a first crosslinkable hydrophilic polymer, and a crosslinker for the first crosslinkable hydrophilic polymer; annealing the slurry deposited on the substrate to create a crosslinked porous layer on the substrate; depositing an solution comprising an ion-exchange material, a second crosslinkable hydrophilic polymer, and a crosslinker for the second crosslinkable hydrophilic polymer onto the crosslinked porous layer; and optionally annealing and/or drying the solution on the crosslinked porous layer.

Abstract: Asphaltene may be effectively broken into smaller molecules by first elucidating the structure of the asphaltene and then developing a catalyst system based on the elucidated structure. The structure may be determined based on a series of analytical techniques including NMR, FTIR, Raman spectroscopy, XPS, and LDI. The most probable structure is determined using computational methods based on quantum mechanics and classical molecular dynamics and the catalyst system is developed for the most probable structure.

Abstract: Systems and methods for fracture mapping may utilize frequency changing to aid in providing high-resolution mapping. Integrated chips may be injected into a well and dispersed into a formation. A downhole tool that provides a transmitter and receiver may be positioned in the well. The transmitter may transmit electromagnetic (EM) signals into the formation. The dispersed integrated chips may receive the transmitted EM signal and return a frequency-changed signal to the receiver of the downhole tool. Utilizing the returned frequency changed signal, the system is able to determine the locations of the integrated chips that have been dispersed into the formation and provide fracture mapping. In another variation, the integrated chips may communicate with each other to provide fracture mapping.

Abstract: Embodiments of a capo and fretting component are described. In certain embodiments, the fretting component is threaded onto a crossbar configured to overlie the instrument strings when in use and to pivot with respect to the crossbar so as to contact and press the strings against a fret on the instrument neck. The fretting component is offset with respect to the attachment mechanism of the capo, allowing the attachment mechanism to be offset on the neck of the instrument from where it would normally be positioned to achieve a comparable fretting effect.

Abstract: A well monitoring system may provide a plurality of integrated chips dispersed in cement surrounding a well casing. Each of the integrated chips may provide energy harvesting circuitry, EM transceiver, modulator, additional sensor(s), processor or microprocessor, memory, power source, or the like. Upon analyzing data gather from the sensor(s), emitted and detected EM waves, the system may provide information about the cement thickness at different parts of the well, cement setting/curing, local electrical permittivity, local magnetic permeability, temperature, pressure, pH, local NMR spectrum, local ESR spectrum, local florescence response, local porosity, local permeability, etc. Further, the integrated chips may be utilized to transmit/receive the abovementioned data, other data (e.g. command data, power signal, etc.), or the like to/from the main transceiver.