Abstract: Real-world data may not be sparse in a fixed basis, and current high-performance recovery algorithms are slow to converge, which limits compressive sensing (CS) to either non-real-time applications or scenarios where massive back-end computing is available. Presented herein are embodiments for improving CS by developing a new signal recovery framework that uses a deep convolutional neural network (CNN) to learn the inverse transformation from measurement signals. When trained on a set of representative images, the network learns both a representation for the signals and an inverse map approximating a greedy or convex recovery algorithm. Implementations on real data indicate that some embodiments closely approximate the solution produced by state-of-the-art CS recovery algorithms, yet are hundreds of times faster in run time.

Abstract: Embodiments of the invention are directed to Ubx-fusion molecules that maintain their mechanical strength and properties even after being fused with Ubx. Ubx fusions with VEGF and other growth factors, cell signaling proteins, and cell binding proteins can be used to induce angiogenesis. Ubx fibers and mesh, embedded within a tissue engineering scaffold, induce formation of vasculature within the scaffold. The presence of vasculature is necessary to provide oxygen and nutrients to other cells growing within the scaffold.

Abstract: Provide is a cement ink for a cement ink for 3D printing (which also includes additive manufacturing) of 3D cement structures and materials. The cement ink includes an American Petroleum Institute (API) Class G cement, a nano-clay, a superplasticizer, a hydroxyethyl cellulose, and a defoamer. The nano-clay may be hydrophilic bentonite. The superplasticizer may be a polycarboxylate ether. The defoamer may be 2-ethyl-1-hexanol. Processes for forming the cement ink and printing 3D cement structures using the cement ink are also provided.

Abstract: A multicomponent photocatalyst includes a reactive component optically, electronically, or thermally coupled to a plasmonic material. A method of performing a catalytic reaction includes loading a multicomponent photocatalyst including a reactive component optically, electronically, or thermally coupled to a plasmonic material into a reaction chamber; introducing molecular reactants into the reaction chamber; and illuminating the reaction chamber with a light source.

Abstract: Provided herein are reagents and methods for simultaneously enriching many potential rare genetic variants at different genetic loci. The rare variants enriched can include single nucleotide polymorphisms (SNPs), single nucleotide variants, or small insertions and deletions. Embodiments of the invention include procedures for integration with downstream next generation sequencing (NGS) analysis. Embodiments of the invention include analysis of nonpathogenic SNPs for the determination of cell identity and detection of cell contamination using qPCR or NGS.

Abstract: In one aspect, the present invention provides novel derivatives of trioxacarin analogs of the formula (I) wherein the variables are as defined herein. The application also provides compositions, methods of treatment, and methods of synthesis thereof.

Abstract: Compositions and methods for highly specific nucleic acid probes and primers are provided. The probe system comprises a complement strand and a protector stand that form a partially double-stranded probe. The reaction standard free energy of hybridization between the probe and target nucleic acid as determined by Expression 1 (?G°rxn=?G°t-TC??G°nh-PC+(?G°v-TC??G°h-PC)) is from about ?4 kcal/mol to about +4 kcal/mol. Alternatively, the reaction standard free energy of hybridization between the probe and target nucleic acid is determined by Expression 1 to be within 5 kcal/mol of the standard free energy as determined by Expression 2 (?R? ln(([P]0?[C]0)/[C]0)]), where the [P]0 term of Expression 2 equals the concentration of the protector strand and the [C]0 term of Expression 2 equals the concentration of the complement strand. In addition, a method for on-the-fly fine tuning of a reaction using the present probe is provided.

Abstract: In one aspect, the present disclosure provides new analogs of uncialamycin. The present disclosure also provides novel synthetic pathways to obtaining uncialamycin and analogs thereof. Additionally, the present disclosure also describes methods of use of uncialamycin and analogs thereof. In another aspect, the present disclosure provides antibody-drug conjugates which may be used to treat cancer or another disease or disorder.

Abstract: In one aspect, the present disclosure provides epothilone analogs of the formula (I) wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein. Additionally, drug conjugates with cell targeting moieties of the compounds are also provided.

Abstract: Asphaltene produced during the production of hydrocarbons in an underground reservoir may be reduced and decomposed by introducing into the underground reservoir a fluid having a catalyst of from about 3 to about 7% Ni with a magnesium oxide support or a catalyst of from about 15 to about 25% tungsten oxide with a zirconium oxide support or a mixture thereof. The viscosity of heavy oil within the underground reservoir is reduced in the presence of the catalyst.

Abstract: A process for extracting, recovering and recycling metals and materials from spent lithium ion batteries (LIB) that comprises the contacting battery waste products with a deep eutectic solvent, and leaching the metal from the battery waste product and extracting the metal into the deep eutectic solvent with heat and agitation. After the leaching and extracting, the process further includes recovering the dissolved metals ions from the deep eutectic solvent solution, followed by a step of regeneration of cathode materials.

Abstract: An infrared photodetector includes: a p-type and highly-doped silicon substrate; a metal structure disposed on the silicon substrate; a first electric contact to the silicon substrate; and a second electric contact to the metal structure.

Abstract: The present disclosure provide viral compositions and methods for modulating adeno-associated virus properties including transduction efficiency, virus capsid assembly, viral genome packaging, capsid stability and intracellular processing. Engineered adeno-associated viruses with modifications in the N-terminal region of the capsid proteins VP1 or VP2 are provided which have varying effects on viral properties including transduction efficiency. Corresponding nucleic acids and amino acids are provided.

Abstract: The present disclosure describes a genetically engineered a KASIII-independent fatty acid biosynthetic pathway that makes use of the promiscuous nature of the rest of the FAS enzymes (3-ketoacyl-ACP synthetase, 3-ketoacyl-ACP reductase, 3-hydroxyacyl ACP dehydrase, enoyl-ACP reductase) to bypass the KASIII step by providing a Co-A precursor of two or higher than two carbons (such as the four carbon butyryl-CoA) as the starting molecule. Since many CoA-based starter molecules can be supplied for the fatty acid synthesis, much more diversified products can be obtained with various carbon-chain lengths. As such, this disclosure will serve as a powerful and efficient platform to produce low to medium chain length products carrying many different functional groups.

Abstract: Systems and methods generally useful in medicine, cellular biology, nanotechnology, and cell culturing are discussed. In particular, at least in some embodiments, systems and methods for magnetic guidance and patterning of cells and materials are discussed. Some specific applications of these systems and methods may include levitated culturing of cells away from a surface, making and manipulating patterns of levitated cells, and patterning culturing of cells on a surface. Specifically, a method of culturing cells is presented. The method may comprise providing a plurality of cells, providing a magnetic field, and levitating at least some of the plurality of cells in the magnetic field, wherein the plurality of cells comprise magnetic nanoparticles. The method may also comprise maintaining the levitation for a time sufficient to permit cell growth to form an assembly.

Abstract: In some embodiments, the present disclosure pertains to systems and methods for distilling a fluid by exposing the fluid to a porous membrane that includes a surface capable of generating heat. In some embodiments, the heat generated at the surface propagates the distilling of the fluid by converting the fluid to a vapor that flows through the porous membrane and condenses to a distillate. In some embodiments, the surface capable of generating heat is associated with a photo-thermal composition that generates the heat at the surface by converting light energy from a light source to thermal energy. In some embodiments, the photo-thermal composition includes, without limitation, noble metals, semiconducting materials, dielectric materials, carbon-based materials, composite materials, nanocomposite materials, nanoparticles, hydrophilic materials, polymers, fibers, meshes, fiber meshes, hydrogels, hydrogel meshes, nanomaterials, and combinations thereof.

Abstract: The present disclosure provides compositions and methods for producing hydrogel matrix constructs. Methods of using hydrogel matrix constructs for tissue repair and regeneration and for the oxygenation of red blood cells are also disclosed.

Abstract: The disclosure relates to a class of diol-based, unsaturated aliphatic polyesters that biodegrade into monomers capable of mitigating infection. These poly(diol fumarates) (PDFs) and poly(diol fumarate-co-succinates) (PDFSs), can be crosslinked to form networks of scaffolds with antimicrobial degradation products. Both the diol carbon length and the degree of available double bonds are tunable, resulting in a highly controllable class of antimicrobial polymers useful for cell scaffolds and drug delivery systems and devices.

Abstract: A client device includes a processor and an antenna. The client device obtains an announcement that specifies a winning client of a channel contention competition; identifies a group association of the client device using an identity of the winning client; transmits a preamble modulated by an entry of a preamble interference nullification matrix, the entry is based on the group association; and transmits, after transmitting the preamble, a data transmission. The preamble is transmitted at the same time as a second preamble is transmitted by a second client device.

Abstract: A method for a passive single-viewpoint 3D imaging system comprises capturing an image from a camera having one or more phase masks. The method further includes using a reconstruction algorithm, for estimation of a 3D or depth image.