Abstract: Substituted thenoylacetic acid and esters, and pharmaceutically acceptable salts thereof of the following general formula are useful as hypolipidemic agents: ##STR1## wherein Y is selected from oxygen and divalent sulfur; R is selected from a straight or branched saturated hydrocarbon chain containing from 10 to 20 carbon atoms and a straight or branched unsaturated hydrocarbon chain containing from 10 to 20 carbon atoms and from 1 to 4 double bonds; R.sub.1 is selected from hydrogen and an ester group.

Abstract: L-3-Hydroxymethyltyrosine and pharmaceutically acceptable salts thereof useful in lowering blood pressure and compositions thereof.

Abstract: The present invention concerns derivatives of androst-4-en-19-one which are useful in the enhancement of libido and related psychic attitudes.

Abstract: Novel 7-[.alpha.-amino-.omega.-(3,4-methylenedioxyphenyl)acylamido]cephalosporan ic acid derivatives are prepared which are useful as antibacterial agents.

Abstract: The compounds are 7-substituted-2-indolinones which are useful as anticonvulsant agents. Representative of the compounds are 7-chloro-3-hydroxy-3-phenyl-indolin-2-one, 7-bromo-3-hydroxy-3-phenyl-2-indolinone, and 7-chloro-3-hydroxy-3-methyl-2-indolinone.

Abstract: The method comprises administering to an animal a novel pharmaceutical composition containing a substituted-1-oxo-1H-2-benzothiopyran-3-carboxylic acid to inhibit antigen-antibody reaction in said animal. Representative of the compounds that can be used in the method are:1-Oxo-1H-2-benzothiopyran-3-carboxylic acid, andSodium 6-methoxy-1-oxo-1H-2-benzothiopyran-3-carboxylate.

Abstract: Substituted thiophenecarboxylic acids and esters and pharmaceutically acceptable salts thereof of the following general structure are useful as hypolipidemic agents: ##STR1## wherein R is selected from a straight or branched saturated hydrocarbon chain containing from 10 to 20 carbon atoms and a straight or branched unsaturated hydrocarbon chain containing from 10 to 20 carbon atoms and from 1 to 4 double bonds; R.sub.1 is selected from hydrogen, a straight or branched lower alkyl chain of from 1 to 6 carbon atoms, benzyl, phenethyl, pyridyl-methyl, alkane-poly-yl containing from 3 to 6 carbon atoms, 1,2,3,4,5,6-cyclohexanehexayl, and Z; Z is selected from ##STR2## wherein n is the integer 2 or 3; R.sub.2 is selected from a straight or branched lower alkyl chain of from 1 to 4 carbon atoms, and alkylcarbonyl wherein the alkyl moiety contains from 1 to 4 carbon atoms and may be straight or branched; R.sub.

Abstract: A method of promoting the growth of ruminants and poultry without concommitant adrogenizing effects using the following compound: ##STR1## wherein R is --CHO or --CH.sub.2 OR.sub.1 ; each of R.sub.1 and R.sub.2 is hydrogen, alkylcarbonyl wherein the alkyl moiety has from 1 to 20 carbon atoms and is straight or branched, benzoyl, phenylalkylcarbonyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched or cycloalkylcarbonyl wherein the cycloalkyl moiety has from 5 to 10 carbon atoms; R.sub.3 is hydrogen; or R.sub.2 and R.sub.3 together form a double bond between the 17- position carbon atom and the oxygen atom.

Abstract: Substituted thiophenecarboxylic acid and esters and pharmaceutically acceptable salts thereof of the following general structure are useful as hypolipidemic agents: ##STR1## wherein Y is selected from oxygen and divalent sulfur; R is selected from a straight or branched saturated hydrocarbon chain of from 10 to 20 carbon atoms and a straight or branched unsaturated hydrocarbon chain containing from 10 to 20 carbon atoms and from 1 to 4 double bonds; R.sub.1 is selected from hydrogen, a straight or branched lower alkyl group of from 1 to 6 carbon atoms, benzyl, phenethyl, alkane-poly-yl containing from 3 to 6 carbon atoms, and 1,2,3,4,5,6-cyclohexanehexayl; X is an integer of from 1 to 6 with the proviso that when R.sub.1 is alkane-poly-yl or 1,2,3,4,5,6-cyclohexanehexayl, X is equal to from 2 to 6, and when R.sub.1 is other than alkane-poly-yl or 1,2,3,4,5,6-cyclohexanehexayl, X is equal to 1.

Abstract: Substituted thiophene and furan carboxaldehydes of the following general Structure are useful as hypolipidemic agents: ##STR1## wherein Y is selected from oxygen and divalent sulfur; R is selected from a straight or branched saturated hydrocarbon chain having from 10 to 20 carbon atoms and a straight or branched unsaturated hydrocarbon chain having from 10 to 20 carbon atoms and from 1 to 4 double bonds; X is selected from oxygen and divalent sulfur.

Abstract: Novel [substituted(2,4-dioxo-1-pyrimidinyl)acetylamino]penicillin and cephalosporin derivatives are prepared which are useful antibacterial agents.

Abstract: Novel 2,7-bis basic alkanol derivatives of xanthene and thioxanthene, their preparation and use for the prevention and inhibition of viral infections are disclosed.

Abstract: Pyrazole derivatives of the general formula: ##STR1## wherein R.sub.1 and R.sub.2 are each hydrogen, methyl, ethyl, n-propyl, isopropyl, or n-butyl and X is hydrogen, hydroxy, methyl, methoxy, chlorine, or bromine, and their acid addition salts have antiviral activity against both RNA and DNA viruses such as myxoviruses, adenoviruses, rhinoviruses, and various viruses of the Herpes group. The compounds are active when administered orally or topically. They may be prepared by heating hydrazine hydrate or an alkyl hydrazine with a 3-benzofuryl ketone.

Abstract: 7.alpha.-Methylestr-4-ene-3.alpha.,17.beta.-diol and derivatives thereof useful as antifertility agents.

Abstract: Substituted furoylacetic acids and esters, and pharmaceutically acceptable salts thereof of the following general structure are useful as hypolipidemic agents: ##STR1## wherein Y represents oxygen or divalent sulfur; R represents a straight or branched alkyl chain containing from 10 to 20 carbon atoms and may be saturated or may be unsaturated containing from 1 to 4 double bonds; R.sup.1 represents hydrogen, or an ester group.

Abstract: The compounds are N-substituted-dihydroxyphenethylamines which are cardiotonic agents, central nervous system depressants and analgetic agents. Representative of the compounds disclosed is N-(3,4-dihydroxyphenisobutyl)-.beta.-isopropyl-3,4-dihydroxyphenethylamine .

Abstract: A cervical tissue cell-gathering device is provided which can be self-administered, and which is so arranged as to protect the sample from contamination as it is inserted and withdrawn from the vagina. An improved method for the preparation of Pap smear slides using such a device is described.

Abstract: A hinged box which has two hinges protruding from the back of the box, each hinge member composed of five ball elements which are interlocked. Two balls of each group of the five elements have grooves extending across opposite faces of the ball members, at least halfway but not entirely across, which provide pockets for the three other ball members whereby the five ball members are locked securely in a rotatable position to form a hinge. Each of the two parts of the box has at the back two ball elements on one side of the box and three at the other side of the back. A further improvement in the hinged box comprises longitudinal cylindrical bar-like members protruding from the back of each section of the box and resting in grooves on the other section of the box. This construction adds strength and stiffness to the hinge without impairing the smooth action of the hinge when opening and closing the lid on the box.

Abstract: Novel [substituted(2-oxo-1-pyridinyl)acetylamino] penicillin and cephalosporin derivatives are prepared which are useful antibacterial agents.

Abstract: Novel 6-[.alpha.-amino-.omega.-(3,4-methylenedioxyphenyl)acylamido] penicillanic acid derivatives are prepared which are useful as antibacterial agents.