Patents Assigned to Riken
  • Publication number: 20240226278
    Abstract: The present disclosure provides an artificial adjuvant vector cell inducing an immune response to a spike protein of a coronavirus, a pharmaceutical composition containing the cell, and use of the cell and the composition. According to the present disclosure, the cell can be an artificial adjuvant vector cell (aAVC) expressing a spike protein of a coronavirus.
    Type: Application
    Filed: April 28, 2022
    Publication date: July 11, 2024
    Applicant: RIKEN
    Inventors: Shin-ichiro FUJII, Kanako SHIMIZU
  • Patent number: 12035456
    Abstract: A magneto-optical trap method including applying a magnetic field to an atom encapsulated in a vacuum vessel and having a nuclear spin of not less than 3/2 by using an anti-Helmholtz coil. Then generating a laser beam including a first laser beam detuned from a first resonance frequency when the atom transits from a total angular momentum quantum number F in a ground state to a total angular momentum quantum number F?=F+1 in an excited state, and a second laser beam detuned from a second resonance frequency when the atom transits from the total angular momentum quantum number F in the ground state to a total angular momentum quantum number F?=F?1 in the excited state.
    Type: Grant
    Filed: September 5, 2023
    Date of Patent: July 9, 2024
    Assignees: NIPPON TELEGRAPH AND TELEPHONE CORPORATION, RIKEN
    Inventors: Hiromitsu Imai, Tomoya Akatsuka, Katsuya Oguri, Atsushi Ishizawa, Hideki Gotoh, Hidetoshi Katori, Masao Takamoto
  • Patent number: 12031281
    Abstract: A vision guide with a light guiding rod including rope member formed by twisting plural strands; light guiding rod of circumferentially light emitting type being adheringly wound around spiral indentations formed between strands on outer circumference of rope member with core layer made of acrylic-based resin and clad layer made of fluorine-based resin; and light source attached to end portion of light guiding rod, wherein amount of change luminance of light guiding rod in test time over duration of 1000 hours by accelerated weathering tester is contained within range of ±10%; amount of change in each numerical value of chromaticity [x, y] is contained within range of ±0.02; flexural modulus of elasticity of light guiding rod under atmosphere of ?20 degrees Centigrade is contained at range of 0.5-5.0×103 MPa; rope member is formed by twisting strands at twisting angle from 10°-20°; and spiral indentations are uniformly formed with pitch from 100 mm-200 mm.
    Type: Grant
    Filed: April 15, 2019
    Date of Patent: July 9, 2024
    Assignees: FUKUVI CHEMICAL INDUSTRY CO., LTD., RIKEN KOGYO INC.
    Inventors: Yuto Usui, Kodai Hatakeyama, Tatsuya Yamazaki, Yukihiro Shibao
  • Publication number: 20240215588
    Abstract: A spider mite repellent comprises at least one oil selected from the group consisting of olive oils, olive pomace oils, and partially hydrogenated high-oleic rapeseed oils as an active ingredient.
    Type: Application
    Filed: January 24, 2022
    Publication date: July 4, 2024
    Applicant: RIKEN
    Inventor: Yutaka ARIMOTO
  • Publication number: 20240216440
    Abstract: The present invention provides a transplant material of a retinal pigment epithelial cell that can be prepared in a short time at a low cost, and that can be easily controlled at the site of transplantation even though the transplantation method is non-invasive, and a method for producing such transplant material.
    Type: Application
    Filed: April 28, 2022
    Publication date: July 4, 2024
    Applicant: RIKEN
    Inventors: Masayo TAKAHASHI, Yuji TANAKA, Yo TANAKA, Nobuyuki TANAKA, Satoshi AMAYA, Mitsuhiro NISHIDA, Michiko MANDAI
  • Patent number: 12029126
    Abstract: A compound containing Sn, Te and Mg, and further containing either one or both of Sb and Bi.
    Type: Grant
    Filed: December 2, 2019
    Date of Patent: July 2, 2024
    Assignees: SUMITOMO CHEMICAL COMPANY, LIMITED, RIKEN
    Inventors: Atsunori Doi, Satoshi Shimano, Yasujiro Taguchi, Yoshinori Tokura
  • Publication number: 20240207483
    Abstract: The present invention relates to a therapeutic drug for a disease accompanied by a disorder in retinal cells or a retinal tissue, the drug including a retinal tissue, the retinal tissue being of an allogeneic origin and having a three-dimensional structure, wherein an intended patient to be given the therapeutic drug is a patient affected by a disease accompanied by a disorder of retinal cells or a retinal tissue, to be given systemically, for 1 month or more after the administration of the therapeutic drug, no immunosuppressive agent aimed at preventing graft rejection.
    Type: Application
    Filed: December 27, 2019
    Publication date: June 27, 2024
    Applicants: Riken, Sumitomo Pharma Co., Ltd., Sumitomo Chemical Company, Limited
    Inventors: Sunao Sugita, Michiko Mandai, Masayo Takahashi, Suguru Yamasaki
  • Publication number: 20240206703
    Abstract: A tomographic image processing device generates a pseudo tomographic image from a moving image in which a cross section is captured via a light-receiving surface of a puncture member that punctures a living body. Herein, an acquirer acquires the moving image in which the cross section is captured via the light-receiving surface of the puncture member that punctures the living body. A corrector performs image correction of each frame of the moving image, based on a shape of the light-receiving surface. A tracker tracks a candidate for a picture of tissue of the living body that satisfies a desired tracking condition. An estimator estimates a representative vector, based on a movement vector of the candidate. An extractor extracts a candidate in which the movement vector is similar to the representative vector.
    Type: Application
    Filed: March 30, 2022
    Publication date: June 27, 2024
    Applicant: RIKEN
    Inventors: Yosky Kataoka, Sally Danno, Toshiyuki Goto, Kazuo FUNABIKI, Ichiro NAKAHARA, Akira MIZOGUCHI
  • Publication number: 20240194701
    Abstract: A light-receiving element according to an embodiment of the present disclosure includes: a semiconductor substrate including a photoelectric conversion region; a first first electrically-conductive region provided at an interface of a first surface of the semiconductor substrate and coupled to a first electrode; a second first electrically-conductive region provided at the interface of the first surface and around the first first electrically-conductive region and coupled to a second electrode; a third first electrically-conductive region provided at the interface of the first surface and around the second first electrically-conductive region and being in an electrically floating state; and an electrically-conductive film provided above the first surface at least between the first first electrically-conductive region and the second first electrically-conductive region.
    Type: Application
    Filed: March 25, 2022
    Publication date: June 13, 2024
    Applicants: SONY SEMICONDUCTOR SOLUTIONS CORPORATION, RIKEN
    Inventors: Takaki HATSUI, Takahiro KAWAMURA, Hiroki TOJINBARA, Kazunobu OTA, Toru SHIRAKATA, Hikaru IWATA, Atsuhiro ANDO
  • Publication number: 20240190818
    Abstract: The present invention relates to a compound represented by the following formula (I): and an antimalarial drug comprising the compound.
    Type: Application
    Filed: March 3, 2022
    Publication date: June 13, 2024
    Applicant: RIKEN
    Inventors: Hiroyuki OSADA, Takayuki MOTOYAMA, Islam Adel ABDELHAKIM, Yushi FUTAMURA
  • Publication number: 20240192153
    Abstract: A nondestructive inspection system 1 is provided with: a neutron radiation unit 10 capable of radiating a first neutron dose of neutrons; a neutron detection unit 20 capable of detecting a second neutron dose of neutrons scattered inside an inspection object A upon radiation of neutrons from the neutron radiation unit 10; a gamma ray detection unit 30 capable of detecting a gamma ray dose released from the inspection object A upon radiation of neutrons from the neutron radiation unit 10; and an analysis unit 50 that calculates the contained amount of a predetermined substance on the basis of the gamma ray dose and corrects the contained amount of the predetermined substance on the basis of the first neutron dose and the second neutron dose.
    Type: Application
    Filed: March 31, 2022
    Publication date: June 13, 2024
    Applicants: TOPCON CORPORATION, RIKEN
    Inventors: Shigenori NAGANO, Satoshi YANOBE, Akira YAJIMA, Hanako AIKOH, Satoru ISHIGURO, Yoshie OTAKE, Yasuo WAKABAYASHI, Masato TAKAMURA
  • Publication number: 20240180485
    Abstract: The present invention provides a method for inducing a hibernation-like state and an apparatus therefor. According to the present invention, provided is a method for decreasing a theoretical setpoint temperature of body temperature and a feedback gain of heat generation in a subject or a method for inducing a hibernation-like state in a subject, the method being a chemical and/or physical method including providing an excitatory stimulus to a pyroglutamylated RFamide peptide (QRFP)-producing neuron. According to the present invention, an apparatus used to practice this method is also provided.
    Type: Application
    Filed: March 30, 2022
    Publication date: June 6, 2024
    Applicants: University of Tsukuba, RIKEN
    Inventors: Takeshi SAKURAI, Genshiro SUNAGAWA
  • Publication number: 20240185438
    Abstract: A computer-implemented method for detecting objects in the field of view of an optical detection device is provided that includes (i) acquiring, through the optical detection device, a plurality of subsequent frames of a portion of an observed space in a time interval, wherein each frame is acquired in a corresponding time instant of the time interval; (ii) selecting a subset of frames from the plurality of frames; (iii) for each set of values of shifting parameters of a plurality of sets of values of shifting parameters that are indicative corresponding predetermined motions of an object with respect to the optical detection device, determining a corresponding first stacked frame on the basis of the subset of frames and as a function of the set of values of the shifting parameters; (iv) for each first stacked frame, determining whether the first stacked frame belongs to a first or a second class, wherein the first and the second class are respectively indicative of the presence or absence of an image of an o
    Type: Application
    Filed: April 15, 2022
    Publication date: June 6, 2024
    Applicants: Universita' Degli Studi Di Torino, RIKEN
    Inventors: Antonio Montanaro, Mario Edoardo Bertaina, Toshikazu Ebisuzaki
  • Publication number: 20240183801
    Abstract: A nondestructive inspecting device 1 is provided with: a neutron beam emitting unit 10 capable of emitting a neutron beam in a prescribed emission direction D1; a gamma ray detecting unit 20 capable of detecting a gamma ray incident from a prescribed detection direction D2 intersecting the emission direction D1; a device housing 30 which covers the neutron beam emitting unit 10 and the gamma ray detecting unit 20, and in which an opening portion 30a is formed in the emission direction D1 and the detection direction D2; an outer shutter 31 for opening and closing the opening portion 30a of the device housing 30; an external dose monitor 41 for detecting a radiation dose inside the device housing 30; an internal dose monitor 42 for detecting a radiation dose outside the device housing 30; and a control unit 40 for prohibiting opening of the outer shutter 31 if the radiation dose detected by at least either of the dose monitors 41, 42 exceeds a predetermined threshold.
    Type: Application
    Filed: March 31, 2022
    Publication date: June 6, 2024
    Applicants: TOPCON CORPORATION, RIKEN
    Inventors: Shigenori NAGANO, Satoshi YANOBE, Akira YAJIMA, Hanako AIKOH, Satoru ISHIGURO, Yoshie OTAKE, Yasuo WAKABAYASHI, Masato TAKAMURA
  • Patent number: 12000699
    Abstract: Provided is an optical interference measuring apparatus including a measuring unit for acquiring an interferogram of an interference wave obtained by irradiating a measuring target and a reference surface with electromagnetic waves and causing reflected waves from a reflecting surface of the measurement target and reflected waves from the reference surface to interfere and a signal processing unit for configuring an intensity profile in the depth direction by performing Fourier transform of the interferogram. The signal processing unit is configured to estimate a parameter for a model formula for an assumed surface count, based on the model formula of an interferogram when it is assumed that the measurement target has a predetermined structure, to select an optimal model by a statistical technique from the model formula to which a parameter estimated for the assumed surface count is applied, and to reconfigure an intensity profile based on the optimal model.
    Type: Grant
    Filed: May 25, 2020
    Date of Patent: June 4, 2024
    Assignees: TOPCON CORPORATION, RIKEN
    Inventors: Homare Momiyama, Yoshiaki Sasaki, Isao Yoshimine, Chiko Otani, Tetsuya Yuasa
  • Patent number: 12002376
    Abstract: Provided is a system that enables training for catheter surgery without using radiation. The system offering training for catheter surgery includes: a light source; a blood vessel model to which a catheter having a fluorescent agent applied thereto is inserted; a tank in which the blood vessel model is placed; a filter for rejecting white light that is not transmitted through the blood vessel model, of illuminating light from the light source; a camera for imaging fluorescence transmitted through the filter; a driver for changing the attitude of the light source; and a computer that performs a process of reversing black and white of an image signal output from the camera.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: June 4, 2024
    Assignees: RIKEN, UNIVERSITY OF THE RYUKYUS
    Inventors: Hideo Yokota, Yusuke Ohya, Masashi Iwabuchi
  • Patent number: 11987692
    Abstract: Provided is a thermoplastic resin composition or an adhesive coating material capable of adhering a cyclic polyolefin-based polymer with a metal or metal compound such as aluminum foil or an ethylene-vinyl alcohol copolymer with sufficient strength. The thermoplastic resin composition contains (A) 100 parts by mass of thermoplastic resin; (B) 0.05 to 5 parts by mass of one or more kinds selected from the group consisting of an unsaturated carboxylic acid and an unsaturated carboxylic acid derivative; and (C) 0.01 to 3 parts by mass of organic peroxide; which component (A) contains (a1) 10 to 90% by mass cyclic polyolefin-based polymer; and (a2) 90 to 10% by mass a hydrogenated product of a block copolymer comprising a polymer block composed mainly of an aromatic vinyl compound and a random copolymer block of a conjugated diene compound and an aromatic vinyl compound (with the proviso that the total of the component (a1) and the component (a2) is 100% by mass).
    Type: Grant
    Filed: February 29, 2016
    Date of Patent: May 21, 2024
    Assignee: RIKEN TECHNOS CORPORATION
    Inventors: Ryota Nakanishi, Kosuke Sugiya
  • Publication number: 20240158742
    Abstract: The present invention provides low immunogenic retinal pigment epithelial cells and methods of producing the cells. The present invention contains a step of obtaining a pluripotent stem cell that does not express major histocompatibility complex (MHC) class II protein or lacks the function thereof (step 1), and a step of inducing a retinal pigment epithelial cell from the pluripotent stem cell obtained in step 1 (step 2).
    Type: Application
    Filed: March 8, 2022
    Publication date: May 16, 2024
    Applicant: RIKEN
    Inventors: Sunao SUGITA, Masayo TAKAHASHI, Tomohiro MASUDA
  • Patent number: 11985755
    Abstract: A target structure includes a target and a cooling portion. The target generates neutrons by being irradiated with a charged particle beam. The cooling portion includes a front surface and a back surface that face to sides opposite to each other. The target is joined directly or indirectly to the front surface. A flow path for flowing of cooling liquid including hydrogen elements is formed in the cooling portion. When viewed in a thickness direction of the cooling portion from the front surface to the back surface, the flow path is positioned off a center portion of the target.
    Type: Grant
    Filed: August 1, 2019
    Date of Patent: May 14, 2024
    Assignee: RIKEN
    Inventors: Tomohiro Kobayashi, Yoshie Otake, Hideyuki Sunaga, Xiaobo Li
  • Publication number: 20240154387
    Abstract: A microcavity may include a top layer having a tuned photon energy, a bottom layer, and a quantum well layer in between the top layer and the bottom layer and having a tuned exciton energy independent of the tuned photon energy.
    Type: Application
    Filed: November 3, 2023
    Publication date: May 9, 2024
    Applicants: NTT RESEARCH, INC., RIKEN, The Australian National University
    Inventors: Michael D. Fraser, H. Hoe Tan