Patents Assigned to Riken
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Patent number: 11655347Abstract: In one aspect, the present invention is an organic-inorganic hybrid membrane of a cerium oxide and an organic fluorine compound, the organic-inorganic hybrid membrane satisfying the following (a), (b), and (c): (a) the visible-light transmittance is 70% or higher; (b) the UV transmittance at a wavelength of 380 nm is 60% or lower; and (c) the water contact angle of the surface of the organic-inorganic hybrid membrane is 80° or higher. In another aspect, the present invention is an organic-inorganic hybrid membrane of a cerium oxide and an organic fluorine compound, the organic-inorganic hybrid membrane satisfying the following (a), (b), and (c?): (a) the visible-light transmittance is 70% or higher; (b) the UV transmittance at a wavelength of 380 nm is 60% or lower; and (c?) the water contact angle of the surface of the organic-inorganic hybrid membrane is 90° or higher. The organic fluorine compound may include a fluorine-based resin.Type: GrantFiled: January 16, 2019Date of Patent: May 23, 2023Assignees: HYOMEN KAIMEN KOBO CORPORATION, RIKEN TECHNOS CORPORATIONInventor: Yasunori Taga
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Patent number: 11656159Abstract: The present invention relates to a clearing technique which uses a solution containing at least one of a compound having a delipidation ability, a compound having a biochrome decoloring ability, a compound having a decalcification ability, a compound having a refractive index adjusting ability, and a compound having a tissue swelling ability. The clearing technique is suitable for use in high-throughput and low-magnification imaging which involves a simple process.Type: GrantFiled: April 25, 2017Date of Patent: May 23, 2023Assignee: RIKENInventors: Hiroki Ueda, Kazuki Tainaka, Tatsuya Murakami
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Publication number: 20230152250Abstract: A concentration detector includes: a neutron source emitting neutrons to a target; a gamma ray detector detecting and determining an amount of specific gamma rays that are among gamma rays generated in the target by interactions with the neutrons; and a concentration calculator calculating a concentration of the target at selected depths in the inspection target, based on the detected amount. A relational expression expressing a relation between a plurality of concentrations of the target in a plurality of virtual layers and a detected amount of the specific gamma rays is predetermined for each type of the specific gamma rays or each detection condition. The concentration calculator applies the detected amount for each gamma ray type or each detection condition, to the relational expression for the type or the detection condition, and calculates a concentration of the target component in the layer at each depth or the specific depth.Type: ApplicationFiled: May 10, 2021Publication date: May 18, 2023Applicant: RIKENInventors: Yasuo WAKABAYASHI, Yoshie OTAKE, Yujiro IKEDA
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Patent number: 11643649Abstract: The present disclosure provides a method for screening cells, the method including a step of preparing a plurality of cells which are tagged with a first barcode nucleic acid associated with a test target and treated with the test target, a step of sorting the plurality of cells based on cellular phenotype using an imaging cell sorter, and a step of identifying the test target used to treat each cell using the first barcode nucleic acid as an indicator.Type: GrantFiled: January 12, 2021Date of Patent: May 9, 2023Assignees: ThinkCyte, Inc., The University of Tokyo, RIKENInventors: Asako Tsubouchi, Sadao Ota, Fumiko Kawasaki
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Publication number: 20230127046Abstract: A compound represented by the general formula (I) given below or a pharmacologically acceptable salt thereof has been found to have a strong G9a inhibitory effect. The compound (I) or the pharmacologically acceptable salt thereof inhibits G9a and thereby has high usefulness for the treatment, prevention or suppression of various pathological conditions (proliferative disease such as cancer, ?-globin abnormality, fibrosis, pain, neurodegenerative disease, Prader-Willi syndrome, malaria, viral infection, myopathy, autism, etc.).Type: ApplicationFiled: November 26, 2020Publication date: April 27, 2023Applicants: RIKEN, TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES, MICROBIAL CHEMISTRY RESEARCH FOUNDATIONInventors: Tatsunobu SUMIYA, Yosuke NISHIGAYA, Ryosuke NAMIE, Noriaki HASHIMOTO, Akihiro ITO, Fumiyuki SHIRAI, Ko KIKUZATO, Minoru YOSHIDA
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Patent number: 11630512Abstract: In each trial, brain electrical activity at multiple points of a target person is measured. An acquirer of a determination device acquires response matrices for n trials under a first condition and response matrices form trials under a second condition. An analyzer performs canonical correlation analysis on the acquired response matrices to obtain first canonical variable time series. A distance calculator calculates a distance between the trials from the obtained first canonical variable time series to obtain a distance matrix. A determiner obtains a possibility that the n trials and the m trials are classified into two different clusters from the distance matrix and determines whether the first condition and the second condition are substantially different. It is possible to provide to a single target person a first content in n trials and a second content in m trials so as to determine a difference in interest of the single target person.Type: GrantFiled: May 27, 2016Date of Patent: April 18, 2023Assignee: RIKENInventors: Keiichi Kitajo, Hiromichi Suetani
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Patent number: 11632334Abstract: A first node and a second node transmit packets to a third node via a switch. The packets are buffered in a Tx buffer in the switch and then transmitted to the third node. When the third node detects a sign of congestion at the Tx buffer based on the reception frequency of the packets, it is recognized, from transmitter addresses included in the received packets, that the nodes transmitting the packets to the third node are the first node and the second node, and a control packet for a transmission stop request is transmitted to the first node and the second node. On receiving the control packet for a transmission stop request, the first node stops transmission of only packets addressed to the third node. On receiving the control packet for a transmission stop request, the second node stops transmission of only packets addressed to the third node.Type: GrantFiled: September 7, 2021Date of Patent: April 18, 2023Assignees: FUJITSU LIMITED, RIKENInventors: Junichi Sugiyama, Katsuya Tsushita, Kentaro Sano, Tomohiro Ueno
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Publication number: 20230110760Abstract: The object of the invention is to provide a novel olefin-based molded product useful for various applications. An olefin-based molded product comprising a polymer including a structural unit of at least one polar olefin monomer represented by the general formula (I) CH2=CH—R2—Z(R1)n is provided. In the formula, Z is a hetero atom selected from the group consisting of nitrogen, oxygen, phosphorus, sulfur, and selenium; R1 is a substituted or unsubstituted hydrocarbyl group having 1 to 30 carbon atoms; n is an integer of 1 or 2 depending on the atomic species of Z; and R2 is a substituted or unsubstituted hydrocarbylene group having 2 to 20 carbon atoms.Type: ApplicationFiled: November 17, 2022Publication date: April 13, 2023Applicant: RIKENInventors: Haobing WANG, Yang YANG, Masayoshi NISHIURA, Zhaomin HOU
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Patent number: 11617790Abstract: [Problem to be Solved] Provided is an effective and safe method for treating or preventing a cancer using aAVC. [Solution] The present invention finds suitable ranges of the dose of ?-GalCer loaded on aAVC cell surface, and the amount of ?-GalCer loaded on aAVC cell surface in a pharmaceutical composition comprising aAVC, which are preferred in terms of securing effectiveness and safety in the treatment and prevention of a cancer using aAVC, and provides an effective and safe method for treating or preventing a cancer using aAVC, aAVC for effective and safe treatment or prevention of a cancer, and a pharmaceutical composition comprising the same, etc.Type: GrantFiled: December 1, 2020Date of Patent: April 4, 2023Assignees: Astellas Pharma Inc., RIKENInventors: Keisuke Ohsumi, Taku Yoshida, Masayuki Kanki, Shinichiro Fujii, Kanako Shimizu
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Publication number: 20230094568Abstract: Pluripotent stem cells are suspension-cultured with the undifferentiated state thereof maintained. In suspension culture of pluripotent stem cells, the undifferentiated state is maintained by the presence of a PKC inhibitor, especially, a PKC? inhibitor, and a tankyrase inhibitor (TNKS inhibitor).Type: ApplicationFiled: February 12, 2021Publication date: March 30, 2023Applicants: KANEKA CORPORATION, RIKENInventors: Kazuhiro TAKEUCHI, Masato IBUKI, Yohei HAYASHI, Mami TAKASAKI, Sho KAMBAYASHI, Yoshikazu KAWAI
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Patent number: 11614415Abstract: A non-destructive inspection system includes: a neutron emission unit 12 capable of emitting neutrons pulsed; a neutron detector capable of detecting the neutrons emitted from the neutron emission unit and penetrating through an inspection object; a storage unit storing attenuation information indicating a relationship between a material of the inspection object and attenuation of the neutrons; and a calculation unit capable of calculating distance information indicating a position of a specific portion in the inspection object in accordance with time change information which is information on a change over time in an amount of the neutrons detected by the neutron detector. The calculation unit is capable of generating information related to an amount of the specific portion from information based on the amount of the neutrons according to the time change information, using the distance information and the attenuation information.Type: GrantFiled: February 27, 2020Date of Patent: March 28, 2023Assignees: Topcon Corporation, RIKENInventors: Shigenori Nagano, Satoru Ishiguro, Yoshie Otake, Hideyuki Sunaga, Yuichi Yoshimura, Koji Ikado
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Patent number: 11608505Abstract: It was found that it is possible to construct a genome-edited plant in which no exogenous gene is incorporated in a genome by performing negative selection using morphological defects and the like as indices in a regenerated plant originated from a plant cell in which a gene that induces regeneration of the plant and a gene of the genome editing enzyme are introduced.Type: GrantFiled: November 21, 2018Date of Patent: March 21, 2023Assignee: RIKENInventors: Naoyuki Umemoto, Kazuki Saito
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Patent number: 11609194Abstract: Nuclear spins of particular atoms (14N) which distinctively exist in a crystal of an active pharmaceutical ingredient is manipulated, so that an initial magnetization (modulated magnetization) is caused in nearby hydrogen atoms which exist near the particular atoms in the crystal. The initial magnetization of the nearby hydrogen atoms is spread to peripheral hydrogen atoms which exist at a periphery of the nearby hydrogen atoms in the crystal. A magnetization which is spread in the crystal is directly or indirectly observed.Type: GrantFiled: December 10, 2020Date of Patent: March 21, 2023Assignees: JEOL Ltd., RIKENInventor: Yusuke Nishiyama
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Patent number: 11609190Abstract: The non-destructive inspection method includes: a water absorbing or drying step of changing a water-content state of a test piece; a transmission image capturing step of irradiating, with a radiation, the test piece absorbed water or dried for a predetermined time in the water absorbing or drying step and capturing a transmission image created by visualizing the radiation transmitted through the test piece; and an evaluation step of evaluating the test piece on the basis of the water-content state of the test piece determined from the transmission image captured in the transmission image capturing step.Type: GrantFiled: September 27, 2018Date of Patent: March 21, 2023Assignees: Topcon Corporation, RIKENInventors: Yuichi Yoshimura, Maki Mizuta, Hideyuki Sunaga, Yoshie Otake
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Patent number: 11603129Abstract: A vehicle knuckle 1 includes a main body 10, a strut junction 11 that is positioned at a first side in an extending direction of an axle supported by the main body and fastens a strut damper, and an arm 12 that couples the main body to the strut junction. The vehicle knuckle has a continuous space 17 formed inside the strut junction and the arm. The arm has a first through-hole 17a on a wall 12a that couples an end 10d at the first side of the main body to the strut junction. The first through-hole is formed, with being adjacent to the end at the first side, at the side of the main body with respect to the center of a coupling position of the wall and the main body and a coupling position of the wall and the strut junction and is communicated with the space.Type: GrantFiled: November 26, 2020Date of Patent: March 14, 2023Assignees: KABUSHIKI KAISHA RIKEN, HONDA MOTOR CO., LTD.Inventors: Cakrawala Anang, Tadaaki Kanbayashi, Norikazu Kurosu
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Patent number: 11603417Abstract: An object of the present invention is to provide a novel method of producing a nonpolar olefin polymer (e.g., a copolymer of a nonpolar olefin and a polar olefin). The present invention provides a method of producing a polar olefin polymer or copolymer, the method including the polymerization step of polymerizing a polar olefin monomer using, as a catalyst, a polymerization catalyst composition containing: 1) a metallocene complex represented by Formula (I), which contains a central metal M that is scandium (Sc) or yttrium (Y), a ligand Cp* containing a cyclopentadienyl derivative and being bound to the central metal, monoanionic ligands Q1 and Q2, and W neutral Lewis bases L wherein W is an integer of 0 to 3; and 2) an ionic compound composed of a non-coordinating anion and a cation.Type: GrantFiled: March 14, 2018Date of Patent: March 14, 2023Assignee: RIKENInventors: Chunxiang Wang, Haobing Wang, Yang Yang, Masayoshi Nishiura, Zhaomin Hou
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Patent number: 11600969Abstract: In order to provide a QCL element operating in the near-infrared wavelength range, the present disclosure provides a quantum cascade laser element 1000 having a semiconductor superlattice structure (QCL structure 100) sandwiched between a pair of conductive sections 20 and 30. The semiconductor superlattice structure serves as an active region that emits electromagnetic waves. The active region has a plurality of unit structures 10U that are stacked on top of each other. Each unit structure includes four well layers 10W1-10W4 of a composition of AlxGa1?xN, separated from each other by barrier layers 10B1-10B5 of a composition of AlyGa1?yN with 0?x<y?1. Both of the conductive sections in the pair of conductive sections have a refractive index lower than that of the active region in which doped TCO inserted as a key role.Type: GrantFiled: April 2, 2021Date of Patent: March 7, 2023Assignee: RIKENInventors: Li Wang, Hideki Hirayama
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Publication number: 20230068606Abstract: It has been found that wild-type ferulic acid decarboxylase derived from Saccharomyces has high catalytic activity for the production of unsaturated hydrocarbon compounds. Further, it has been found that in the ferulic acid decarboxylase, substitute of the amino acid at position 398 with glutamine, methionine, asparagine, phenylalanine, histidine, or threonine more improves the catalytic activity, making it possible to provide a method capable of producing an unsaturated hydrocarbon compound such as butadiene with high productivity, and an enzyme used in the method.Type: ApplicationFiled: September 18, 2020Publication date: March 2, 2023Applicants: RIKEN, ZEON CORPORATION, THE Yokohama Rubber Co., Ltd.Inventors: Tomokazu SHIRAI, Yutaro MORI, Kazuhiro TAKAHASHI, Yayoi AKAHORI
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Publication number: 20230064228Abstract: One aspect example is a system for photogrammetry of a building. A memory stores design data and physical material data. The design data includes virtual material information on attributes for each of virtual materials of a virtual building. The physical material data is on the attributes for each of physical materials and generated based on measured data acquired from a physical building constructed on the basis of the design data. A material associating processor is configured to generate pairs of virtual and physical materials by determining an association between the virtual materials and the physical materials based on the virtual material information and the physical material data. An attribute associating processor is configured to determine an association between the virtual material information and the physical material data in accordance with the attributes for each of the pairs.Type: ApplicationFiled: January 20, 2021Publication date: March 2, 2023Applicants: Topcon Corporation, RIKENInventors: Satoshi WADA, Atsushi SHINJO, Takayo OGAWA, Takeharu MURAKAMI, Yasufumi FUKUMA, Zaxing MAO, Satoshi YANOBE, Toshio YAMADA
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Publication number: 20230068445Abstract: A vehicle knuckle 1 includes a main body 10, a strut junction 11 that is positioned at a first side in an extending direction of an axle supported by the main body and fastens a strut damper, and an arm 12 that couples the main body to the strut junction. The vehicle knuckle has a continuous space 17 formed inside the strut junction and the arm. The arm has a first through-hole 17a on a wall 12a that couples an end 10d at the first side of the main body to the strut junction. The first through-hole is formed, with being adjacent to the end at the first side, at the side of the main body with respect to the center of a coupling position of the wall and the main body and a coupling position of the wall and the strut junction and is communicated with the space.Type: ApplicationFiled: November 26, 2020Publication date: March 2, 2023Applicants: KABUSHIKI KAISHA RIKEN, HONDA MOTOR CO., LTD.Inventors: Cakrawala ANANG, Tadaaki KANBAYASHI, Norikazu KUROSU