Abstract: An optical lattice clock includes a clock transition space having disposed therein an atom group trapped in an optical lattice, and a triaxial magnetic field correction coil for correcting the magnetic field of the clock transition space. Additionally, in a correction space that includes the clock transition space and is larger than the clock transition space, a photoreceiver promotes the clock transition of the atom group trapped in the optical lattice and acquires a clock transition frequency distribution for the correction space. Further, a corrector corrects the magnetic field of the triaxial magnetic field correction coil on the basis of the frequency distribution measured by the photo receiver.

Abstract: A marker for examining a diabetic complication comprising a compound represented by the following Formula (1), or a salt thereof.

Abstract: This invention is intended to suppress cell death occurring at the time of transition of adherent culture of pluripotent stem cells to suspension culture thereof. Pluripotent stem cells are subjected to adherent culture in a liquid medium comprising a PKC? inhibitor and a TNKS inhibitor and then to suspension culture.

Abstract: A superconducting coil device according to one embodiment of the present invention includes: A superconducting coil device including: a bobbin having a tubular body; superconducting wires, a part of which constitutes a wound portion where the superconducting wires are wound on the bobbin; a bobbin-side guide portion holding the superconducting wires extending from the bobbin, the bobbin-side guide portion being provided to extend in a bobbin axial direction, which is an axial direction of the body of the bobbin; a first guide portion holding the superconducting wires extending from the bobbin-side guide portion, the first guide portion being arranged on an outer side of the bobbin-side guide portion in a direction intersecting the bobbin axial direction and provided to extend in the direction intersecting the bobbin axial direction; and a second guide portion capable of holding the superconducting wires extending from the first guide portion, the second guide portion being provided to extend in a direction in

Abstract: A gel dosimeter for radiation dosimetry includes a radically polymerizable monomer, a gelator, glucose, and glucose oxidase. Although a conventional polymer gel dosimeter contains a deoxygenating agent such as tetrakis(hydroxymethyl)phosphonium chloride, such a deoxygenating agent fails to exhibit sufficient effects. Thus, a more effective deoxygenation treatment technique has been required for a gel dosimeter.

Abstract: A method includes: inputting an image of a target to each of a first model for estimating a region of an annular face of the target, a second model for estimating a region in an outer circumference of the annular face and a third model for estimating a region in an inner circumference of the annular face, and outputting a region image, as an estimated region of the annular face, the region image being obtained by synthesizing first, second, and third elements. The first element is a region outputted as a result of the first model for calculating a sum set in the synthesizing, the second element is a region outputted as a result of the second model for calculating a sum set in the synthesizing, and the third element is a region outputted as a result of the third model for calculating a difference set in the synthesizing.

Abstract: A method of producing a diffraction grating of borosilicate glass or barium borosilicate glass, the method comprising the steps of forming a grating on a surface of a silicon wafer the grating through the Bosch process; forming an oxide film on a surface of the grating by heating and exposure to water vapor of the silicon wafer; removing the oxide film using hydrofluoric acid; making the surface provided with the grating of the silicon wafer and a surface of a glass plate undergo anodic bonding; heating the silicon wafer and the glass plate bonded to each other; polishing a surface opposite to the boded surface of the silicon wafer and a surface opposite to the boded surface of the glass plate; and removing silicon from the glass plate by selective etching using xenon difluoride.

Abstract: A magnetic resonance measurement apparatus according to the present invention includes a first LC circuit that forms an oscillating magnetic field that causes an object to exhibit magnetic resonance. The first LC circuit includes a parallel connection assembly including a diode. The parallel connection assembly further includes a diode connected, in parallel and in reverse direction, to the diode, or an inductor connected in parallel to the diode. In a first state in which oscillating voltage for forming the oscillating magnetic field is applied to the first LC circuit, the diode of the parallel connection assembly functions as a short-circuit such that the resonance frequency of the first LC circuit becomes a first resonance frequency.

Abstract: A nondestructive inspection apparatus makes a neutron beam incident on an inspection target, detects a specific gamma ray deriving from a target component in the inspection target, among gamma rays generated by the neutron beam, and determines a depth at which the target component exists, based on a result of the detecting. The nondestructive inspection apparatus includes a neutron source that emits a neutron beam to a surface of the inspection target, a gamma ray detection device that detects, as detection intensities, intensities of a plurality of types of specific gamma rays whose energy differs from each other, and a ratio calculation unit that determines a ratio between the detection intensities of a plurality of types of the specific gamma rays.

Abstract: A nondestructive inspecting device (10) includes a neutron emission device (2) that emits a neutron beam to a local irradiation location on a surface (la) of an inspection target (1), a detection device (3) that detects, at each of inspection positions facing the surface (la), scattered neutrons returned from the inspection target (1) as a result of emission of the neutron beam to the irradiation location, and measures the detected number of the scattered neutrons at each of the detection positions, and a ratio calculation unit (5) that calculates, for each of the detection positions, a ratio of the detected number at the detection position to a reference value for the detection position, and outputs the ratios. The reference value is set as the detected number at each of the detection positions in an assumed case of no defects existing in the inspection target (1).

Abstract: To provide an agent that increases expression of genes contributing to hair growth in dermal papilla cells, a scalp care agent, and a hair growth agent which are topical agents that exhibit effect in terms of causing increase in hair shaft diameter and improving maximum hair shaft length and improving hair shaft elongation rate and new hair growth and increasing expression of genes contributing to hair growth in dermal papilla cells and promoting hair shaft growth at head hair, beard, eyelashes, and/or eyebrows, such agents are made to contain an active ingredient in the form of palmitoyl dipeptide-5 diaminobutyloyl hydroxythreonine.

Abstract: The present invention provides a method of obtaining aggregates containing a rostral hypothalamus tissue and a rostral head ectodermal tissue, a hypophysis precursor tissue and a hypophysis hormone producing cell, by using a serum-free medium (preferably substantially free of growth factor and insulins), forming homogeneous aggregates of stem cells from pluripotent stem cells such as ES cell and the like, which are plated at a high cell concentration, and subjecting the formed aggregates to floating-culture.

Abstract: A modified immunocyte: (1) which expresses an exogenous unmodified T cell receptor ?-chain and an exogenous T cell receptor ?-chain on the cell surface thereof; or (2) which contains a polynucleotide encoding a T cell receptor ?-chain and a polynucleotide encoding a T cell receptor ?-chain. Thus, a new tool whereby immunity can be appropriately induced in vivo is provided.

Abstract: Provided is an effective and safe method for treating or preventing a cancer using aAVC. The present invention finds suitable ranges of the dose of ?-GalCer loaded on aAVC cell surface, and the amount of ?-GalCer loaded on aAVC cell surface in a pharmaceutical composition comprising aAVC, which are preferred in terms of securing effectiveness and safety in the treatment and prevention of a cancer using aAVC, and provides an effective and safe method for treating or preventing a cancer using aAVC, aAVC for effective and safe treatment or prevention of a cancer, and a pharmaceutical composition comprising the same, etc.

Abstract: A power generation device includes a filter holder that is a container filled with water and a filter member. The filter member is composed of porous glass in a form of a plate and arranged in the filter holder between a first space upstream from the filter member and a second space downstream from the filter member. The filter member allows hydrogen ions to pass therethrough more easily than hydroxide ions. The power generation device generates electric power based on a potential difference between the first space and the second space when a water flow from the first space toward the second space is produced in the filter member. The water flow flows along a direction of thickness of the filter member.

Abstract: A vehicle knuckle (1) includes a main body portion (10) for supporting an axle, a strut connecting portion (11) for connecting a strut, and an arm portion (12) for connecting the main body portion (10) and the strut connecting portion (11) and having a space (18) inside. The arm portion (12) includes a sidewall portion (120) for connecting the main body portion (10) and the strut connecting portion (11), and has a first through hole (17a) communicating with the space (18), at a coupling portion (12a) with the main body portion (10). The sidewall portion (120) is free of a through hole communicating with the space (18).

Abstract: Strains of human-derived bacteria have been obtained from complex fecal samples and shown to induce accumulation of Th17 cells in the intestine and promote immune functions. Pharmaceutical compositions containing these bacteria can be used as anti-infectives and as adjuvants in mucosal vaccines.

Abstract: The present disclosure is a combination of a cylinder and a piston ring, the combination including a cylinder of an internal combustion engine and a piston ring sliding on an inner peripheral surface of the cylinder. The piston ring has an outer peripheral surface sliding on the inner peripheral surface of the cylinder, and the outer peripheral surface is formed of a substantially hydrogen-free amorphous carbon coating. The Vickers hardness Hd of the amorphous carbon coating and the Vickers hardness Hb of the inner peripheral surface of the cylinder satisfy Hd+Hb?2500 HV. The ratio ID/IG of the peak intensity of the D band to the peak intensity of the G band in a Raman spectrum obtained by measuring the amorphous carbon coating by Raman spectroscopy is 0.60 or more and 1.33 or less.

Abstract: To provide a pharmaceutical composition capable of enhancing the effect of an immune checkpoint inhibitor against tumor or cancer in a subject. Provided is a pharmaceutical composition that comprises bacterial cells, a culture supernatant, a metabolite, and/or a bacterial cell extract of Ruminococcaceae enterobacterium, and is administered in combination with an immune checkpoint inhibitor.

Abstract: A method for detecting a target substance in a sample includes a step of introducing the sample and a reagent that generates a fluorescent substance in a presence of the target substance into each well of a well array; a step of sealing each well of the well array with a sealing liquid such that each well forms an independent reaction space; a step of replacing the sealing liquid with a water-absorbing organic solvent, thereby dehydrating the content of the well, reducing the volume, and generating the fluorescent substance in a case where the target substance is present in the content; and a step of emitting excitation light to the fluorescent substance to detect fluorescent light generated in each well of the well array, in which detection of the fluorescent light in the well indicates the presence of the target substance in the well.