Patents Assigned to Sanofi
  • Patent number: 12083325
    Abstract: Described is a medicament delivery device (1), comprising a body (2), a container carrier (7) for retaining a medicament container within the body (2) and being slidably disposed in the body (2), a sleeve (6) slidably coupled to body (2), and a piston rod (11) coupled to the body (2) and the container carrier (7). The piston rod (11) and the container carrier (7) provide a feedback as the container carrier (7) moves from a first position (P1) to a second position (P2) relative to the body (2).
    Type: Grant
    Filed: January 10, 2023
    Date of Patent: September 10, 2024
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Winfried Huthmacher, Peter Nober
  • Patent number: 12076534
    Abstract: The disclosure relates to a medicament delivery device including an activating mechanism, wherein the activating mechanism includes a hollow injection needle, a cartridge containing a dosage of a medicament, a cartridge carrier including at least one resilient arm for holding the cartridge, a removable needle cap for covering the injection needle, and a drive element adapted to couple with the cartridge, wherein the cartridge is retained in a position spaced apart from the injection needle in a proximal direction (P) by the at least one resilient arm when the medicament delivery device is in an initial position (P1), and wherein by removing the needle cap, the cartridge is releasable to be pushed into a distal direction (D) by the drive element with respect to the cartridge carrier.
    Type: Grant
    Filed: December 26, 2019
    Date of Patent: September 3, 2024
    Assignee: Sanofi
    Inventor: Michael Helmer
  • Patent number: 12076540
    Abstract: An autoinjector includes a case adapted to hold a medicament container having a needle, a needle shroud slidably disposed in the case and translatable between an extended position relative to the case in which the needle is covered and a retracted position relative to the case in which the needle is exposed, and a plunger slidably disposed in the case. The case includes a rib. The plunger includes a plunger boss adapted to abut the rib and the needle shroud when the needle shroud is in the extended position and disengage the rib when the needle shroud is in the retracted position to allow the plunger to translate axially relative to the case.
    Type: Grant
    Filed: January 27, 2022
    Date of Patent: September 3, 2024
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventor: Thomas Kemp
  • Patent number: 12076537
    Abstract: The disclosure relates to an injection device for setting and injecting pre-set or user-selectable doses of a medicament, the injection device comprising an elongated housing defining a longitudinal direction and configured to accommodate a cartridge containing the medicament, and a detector arrangement operable to detect a relative movement between a first element and a second element. The first element is subject to a first movement relative to the second element along a first longitudinal direction for setting of a dose, the first element is subject to a second movement relative to the second element along a second longitudinal direction for dispensing of the dose, one of the first movement and the second movement is a helical movement, and the other one of the first movement and the second movement is a sliding movement in the longitudinal direction. The second element comprises at least one reference element fixed to the second element.
    Type: Grant
    Filed: December 16, 2019
    Date of Patent: September 3, 2024
    Assignee: Sanofi
    Inventors: Oliver Charles Gazeley, Gavin Newman, Aidan Michael O'Hare, David Aubrey Plumptre, Robert Veasey, Craig Ashley Mason, Anthony Paul Morris
  • Patent number: 12076539
    Abstract: An injector device is configurable between a safe state and an operable state and comprises a housing having a distal end and a proximal end; a medicament cartridge disposed within the housing; a needle unit comprising a needle and being disposed in the distal end of the housing; a sleeve displaceable along a longitudinal axis of the device between a first position in which the sleeve conceals the needle and a second position in which the needle is exposed from an end of the sleeve; a locking mechanism configured to prevent displacement of the sleeve when the device is in the safe state; and a button disposed in the proximal end of the housing, the button being configured to switch the device between the safe state and the operable state by releasing the locking mechanism when the button is pressed from an initial position into a depressed position during use.
    Type: Grant
    Filed: February 8, 2019
    Date of Patent: September 3, 2024
    Assignee: Sanofi
    Inventors: Beate Franke, Sean Phillips, Edward Liscio, Nie Weiyan, Marc Anderson, Tim Glässer, Matthias Rau
  • Patent number: 12076535
    Abstract: Described is an autoinjector comprising a case, a door hingedly coupled to the case and having an open position and a closed position, a plunger slidably disposed in the case, and at least one drive spring applying a biasing force on the plunger relative to the case, wherein the door is operably coupled to the plunger, and wherein rotation of the door from the closed position to the open position moves the plunger from a distal position in the case to a proximal position in the case and compresses the at least one drive spring.
    Type: Grant
    Filed: April 21, 2022
    Date of Patent: September 3, 2024
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Charley Henderson, David Cross, Douglas Ivan Jennings, Ryan Anthony McGinley
  • Patent number: 12076541
    Abstract: Described is an autoinjector comprising a case, a chassis slidably arranged in the case, a syringe carrier operably coupled to the chassis, an outer plunger selectively engaged to the chassis, an inner plunger selectively engaged to the outer plunger, and a drive spring applying a biasing force to the outer plunger. The biasing force is applied to the inner plunger when the inner plunger is engaged to the outer plunger. Rotation of the chassis causes the inner plunger to rotate relative to the outer plunger and disengage the outer plunger to remove the biasing force from the drive spring on the inner plunger. When the inner plunger disengages the outer plunger, the biasing force of the drive spring pushes the chassis to retract the syringe carrier relative to the case.
    Type: Grant
    Filed: April 14, 2020
    Date of Patent: September 3, 2024
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Yannick Hourmand, Simon Brereton, Thomas Mark Kemp, Rosie Burnell, Matthew Ekman
  • Patent number: 12076538
    Abstract: An injection device for setting and injecting of a dose of a medicament includes: an acoustic feedback arrangement comprising: a first feedback element having a first engaging section and having a free end section located at a predetermined distance from the first engaging section, a second feedback element having a second engaging section configured to engage with the first engaging section, wherein the first feedback element is movable, pivotable or resiliently deformable along a first direction (d1) relative to the second feedback element from an initial state (i) towards a biased state (b), and a sound generator formed by the first engaging section or audibly engageable with the free end section of the first feedback element.
    Type: Grant
    Filed: October 3, 2022
    Date of Patent: September 3, 2024
    Assignee: Sanofi
    Inventors: Axel Teucher, Michael Jugl, Stefan Blancke
  • Patent number: 12070584
    Abstract: A data collection device for attachment to an injection device, such as an injector pen, includes a sensor arrangement to detect movement of a movable component of the injection device relative to the data collection device during delivery of a medicament by the injection device, and a processor arrangement configured to, based on said detected movement, determine a medicament dosage administered by the injection device. The processor arrangement may monitor the time that has elapsed since the medicament dosage was administered, and control a display to show the mediacament dosage and elapsed time to provide a memory aid to the user. In an example embodiment, the sensor arrangement includes an optical encoder and the movable component includes a plurality of light barrier formations. The movable component may be a number sleeve that provides a visual indication of a dose programmed into the injection device.
    Type: Grant
    Filed: January 12, 2022
    Date of Patent: August 27, 2024
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Frank Erbstein, Paul Richard Draper, Robert Frederick Veasey, David Aubrey Plumptre, Joseph Butler
  • Patent number: 12070590
    Abstract: The present disclosure relates to an injection device including: a housing; a carrier disposed within the housing for holding a syringe that has a needle at one end; a needle sleeve located within the housing and being axially moveable with respect to the housing between an extended position and a retracted position; a biasing element configured to bias the needle sleeve towards the extended position; and a locking mechanism configured to lock the needle sleeve in the extended position after use of the injection device, the locking mechanism comprising; a first locking member provided on and projecting from the carrier; and a second locking member comprising a deflectable arm provided on the needle sleeve and moveable between a relaxed position and a deflected position.
    Type: Grant
    Filed: August 13, 2019
    Date of Patent: August 27, 2024
    Assignee: Sanofi
    Inventors: Uwe Dasbach, Thomas Kemp, Hugo Revellat, Jim Bradford
  • Patent number: 12070589
    Abstract: An autoinjector includes a case adapted to hold a medicament container, a needle shroud telescopically coupled to the case, and a plunger slidably disposed in the case. The needle shroud is movable between a first extended position, a retracted position, and a second extended position relative to the case. The plunger is movable between a proximal position, an intermediate position, and a distal position relative to the case. When the plunger is in the intermediate position and the needle shroud is in the retracted position, the plunger abuts the case to prevent the needle shroud from returning to the extended position. When the plunger is in the distal position and the needle shroud is in the second extended position, the plunger abuts the case to prevent the needle shroud from returning to the retracted position.
    Type: Grant
    Filed: June 24, 2022
    Date of Patent: August 27, 2024
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Stefan Taal, Thomas Kemp
  • Patent number: 12073333
    Abstract: Systems, methods, and computer products can predict rates of hypoglycemia in patients. One of the methods includes receiving data representing medical records of a patient, the patient having been diagnosed with diabetes mellitus. The method includes determine an predicted rate of hypoglycemic events using a machine learning system, the machine being trained using data representing the medical records of a plurality of patients and the corresponding rate of hypoglycemic events for the respective patients. The methods also includes producing the predicted rate for the patient.
    Type: Grant
    Filed: June 21, 2019
    Date of Patent: August 27, 2024
    Assignee: Sanofi
    Inventors: Francisco Javier Jimenez Jimenez, Hsiaohui Wu, Fang Liz Zhou
  • Patent number: 12071454
    Abstract: Antigenic respiratory syncytial virus (RSV) polypeptides for use in eliciting antibodies against RSV are provided. Also provided are antigenic polypeptides comprising an RSV polypeptide and a ferritin protein.
    Type: Grant
    Filed: October 1, 2020
    Date of Patent: August 27, 2024
    Assignee: SANOFI
    Inventors: Gary J. Nabel, Chih-Jen Wei, Kurt Swanson, Pradeep Dhal, Ram Dharanipragada, Magnus Besev
  • Patent number: 12064607
    Abstract: The present invention relates to a drive mechanism of a drug delivery device for setting and dispensing of a dose of a medicament, the drive mechanism comprising: a housing, a piston rod to operably engage with a piston of a cartridge to displace the piston in a distal direction, a rotatable member arranged on an axially extending axis of rotation in the housing, said rotatable member being rotatable in a dose incrementing direction against an action of a spring element and being operably engageable with the piston rod during the dispensing of the dose, and a clutch element comprising at least one radially displaceable clutch element to engage with a rim of the rotatable member with a variably adjustable strength.
    Type: Grant
    Filed: March 1, 2022
    Date of Patent: August 20, 2024
    Assignee: Sanofi
    Inventors: Stefan Bayer, Daniel Berning, Philippe Blank, Wolfgang Pelzer, Björn Wilden
  • Patent number: 12064606
    Abstract: A data collection device including an attachment assembly for attaching the data collection device to a dose setting dial of a medicament administration device, a light source configured to illuminate a portion of a surface of an internal component of the medicament administration device including a pattern of relatively reflective and non-reflecting regions formed on the surface of the internal component, and an optical sensor configured to receive light reflected by at least the relatively reflective regions.
    Type: Grant
    Filed: December 23, 2020
    Date of Patent: August 20, 2024
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Christian Rehbein, Sven Hagebusch, Chris Knorr, Maurice Toporek, Matthias Felber, Alexander Heinrich
  • Publication number: 20240269270
    Abstract: Provided are novel vaccines for prophylactic treatment of SARS-COV-2 infections and COVID-19 and methods of making the vaccines, wherein the vaccines contain an oil-in-water emulsion comprising tocopherol and squalene.
    Type: Application
    Filed: August 23, 2021
    Publication date: August 15, 2024
    Applicants: SANOFI PASTEUR INC., GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Natalie ANOSOVA, Salvador Fernando AUSAR, Catherine BERRY, Florence BOUDET, Thomas BREUER, Danilo CASIMIRO, Roman M. CHICZ, Gustavo DAYAN, Guy DE BRUYN, Carlos DIAZGRANADOS, Tong-Ming FU, Marie GARINOT, Lorry GRADY, Sanjay GURUNATHAN, Kirill KALNIN, Nikolai KHRAMTSOV, Valérie LECOUTURIER, Nausheen RAHMAN, Sophie RUIZ, Stephen SAVARINO, Saranya SRIDHAR, Indresh K. SRIVASTAVA, James TARTAGLIA, Timothy TIBBITTS
  • Patent number: 12059554
    Abstract: The disclosure relates to a drug delivery device including at least a housing, a drug container with a needle, and a cap, wherein the housing has an inner surface forming a cavity configured to retain the drug container, wherein the cap is configured to be releasably connected to the housing, and wherein a back end of the device opposite to a front end of the device directed to the cap includes a gripping lug axially protruding from the back end of the device. The disclosure further relates to an emergency pack including such a drug delivery device.
    Type: Grant
    Filed: January 18, 2018
    Date of Patent: August 13, 2024
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Michael Schabbach, Wolfgang Obermeier
  • Patent number: 12059556
    Abstract: A data collection device comprises an attachment assembly for attaching the data collection device to a dose setting dial of a medicament administration device and a sensor configured to detected an identifier provided on a surface of an internal component of the medicament administration device, the sensor comprising an ultrasound sensor configured to detect a geometric identifier formed on the surface of the internal component of the medicament administration device. A system comprises the data collection device and the medicament administration device.
    Type: Grant
    Filed: September 16, 2022
    Date of Patent: August 13, 2024
    Assignee: Sanofi
    Inventors: Michael Jugl, Michael Schabbach
  • Patent number: 12053503
    Abstract: This disclosure relates to antigenic EBV polypeptides and their use in eliciting antibodies against EBV. Also disclosed are antigenic polypeptides comprising an EBV polypeptide and a ferritin protein.
    Type: Grant
    Filed: June 15, 2023
    Date of Patent: August 6, 2024
    Assignee: SANOFI
    Inventors: Gary J. Nabel, Chih-Jen Wei, Laura Nguyen, Kurt Swanson, Te-Hui Chou
  • Patent number: 12054552
    Abstract: An antibody that specifically binds to IL-1R3, comprising an antibody heavy chain amino acid sequence of SEQ ID NO: 1 and a light chain amino acid sequence of SEQ ID NO: 2. A pharmaceutical composition is provided comprising the said antibody and a pharmaceutically acceptable diluent, carrier or excipient. Also said antibody for use in treating a disease or disorder in a subject in need thereof. The disease or disorder may be an autoimmune or autoinflammatory disease or disorder.
    Type: Grant
    Filed: September 21, 2023
    Date of Patent: August 6, 2024
    Assignee: SANOFI BIOTECHNOLOGY
    Inventors: Christian Lange, Ziyu Li, Björn Steinmann, Hanno Sjuts, Sandra Weil