Patents Assigned to Sartorius
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Patent number: 8845182Abstract: A vessel includes: a pocket capable of assuming a folded state and an expanded state, processing element including an active inner portion; protection element including a side wall, a lower portion and an upper portion defining an inner space, the lower portion being attached to the upper portion of the pocket, the active inner portion being provided in the inner space when the pocket is in the folded state, the peripheral portion of the inner space about the processing element defining a protection chamber; at least one insertion and/or draining opening. The active inner portion is provided inside the pocket adjacent to the lower end portion thereof, the processing element and the protection element are independent in terms of their movements, and the height of the protection chamber is variable and automatically adapts itself based on respectively, the flat-folded, unfolded and expanded states or any intermediate state of the pocket.Type: GrantFiled: October 1, 2008Date of Patent: September 30, 2014Assignee: Sartorius Stedim FMT SASInventors: Frederic Bernard, Eric Chevalier
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Publication number: 20140264100Abstract: A pinch valve with an axially extending tube guide, a clamping jaw (12) which displaces perpendicularly to the axial direction, and an abutment (12; 21) which is opposite the clamping jaw in the jaw displacement direction. The tube guide, the clamping jaw and the abutment are disposed relative to one another such that a flexible tube (18) laid in the tube guide (18) is pinched by the advancing clamping jaw against the abutment. The clamping jaw has a displaceable support element (14) and two claws (16a, 16b) located opposite one another and engaging around the tube guide at least in some regions. The claws are articulated on the support element (14) by the respective rear ends thereof such as to pivot about pivot pins oriented parallel to the axial direction and forming a mouth which opens as the clamping jaw advances and closes as the clamping jaw retracts.Type: ApplicationFiled: May 30, 2014Publication date: September 18, 2014Applicant: Sartorius Lab Instruments GmbH & Co. KGInventors: Swen Weitemeier, Lars Boettcher
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Patent number: 8829367Abstract: Force plate (1) having a plate-shaped carrier (2) which, when arranged vertically, has an upper carrier section (3) at the top in the vertical direction and a lower carrier section (4) at the bottom in the vertical direction. A first end carrier section (5) is connected, on the one hand, to the upper carrier section (3) via a vertical rod (7) and, on the other hand, to the lower carrier section (4) via a horizontally oriented spring element (6). That end of the lower carrier section (4) which faces away from the first end carrier section (5) is connected to the upper carrier section (3) via a horizontal rod (8). A second end carrier section (15) connects the horizontal rod (8) to the lower carrier section (4) via a vertically arranged spring element (16).Type: GrantFiled: May 10, 2011Date of Patent: September 9, 2014Assignee: Sartorius Lab Instruments GmbH & Co. KGInventors: Otto Kuhlmann, Tanja Mueck, Volker Relling, Gerald Petzold
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Publication number: 20140245809Abstract: A carrier unit for a weight switching device includes a first shift weight carrier (34-1) which moves vertically in relation to a base, for vertically mounting a first shift weight arrangement (22-1R, 22-1L) which has two spaced-apart, parallel carrier arms (30-1R, 30-1L) connected by a bridging piece (32-1). A second shift weight carrier (34-2R, 34-2L) for vertically mounting, with play, a second shift weight arrangement (22-2R, 22-2L) which likewise has two spaced-apart, parallel carrier arms (30-2R, 30-2L) connected by another bridging piece (32-2), is likewise arranged in a vertically movable manner in relation to the base. The carrier arm pair (30-1R, 30-10 of the first shift weight carrier (34-1) is arranged between and parallel to the carrier arm pair (30-2R, 30-2L) of the second shift weight carrier (34-2), and each shift weight carrier (34-1; 34-2) is articulated to a common crosspiece (12) by two parallel links (23-1R, 23-1L; 23-2R, 23-2L).Type: ApplicationFiled: May 9, 2014Publication date: September 4, 2014Applicant: Sartorius Weighing Technology GmbHInventors: Sigo Muelich, Ulrich Bajohr, Thomas Fehling
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Patent number: 8822210Abstract: An incubator (1) has an incubation chamber (2) and a shaking device (4) to shake receptacles (5) placed in the incubation chamber (2). A device chamber (3) adjoins the incubation chamber (2) and accommodates at least parts of the shaking device (4). The shaking device (4) has a base plate (8) that seals off the incubation chamber (2) from the device chamber 3. A shaking table (11) is on the inner face (9) of the base plate (8) and can be moved in a horizontal plane by a drive arm (10). A motor (34) is arranged on the outer face (37) of the base plate (8). The motor (34) drives a drive shaft (14) that is rotatably mounted in the base plate (8) and that is operatively connected to the drive arm (10).Type: GrantFiled: February 17, 2009Date of Patent: September 2, 2014Assignee: Sartorius Stedim Biotech GmbHInventors: Reinhard Baumfalk, Stefan Obermann, Rainer Sandrock
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Patent number: 8809765Abstract: A sensor protector is intended to reduce the sensitivity of the optical sensor (4) to radiation products which, for example, are formed during sterilization with gamma radiation and to ensure simple and cost-effective manufacture. The sensor protector includes an upper part (1), a lower part (3) and an optical sensor (4). The optical sensor (4) situated on the lower part is positionable in an offset manner with respect to an opening (2) situated in the upper part and movable by means of displacement toward the opening (2) of the upper part (1). The sensor protector is suitable for use in containers and laboratory products that are sterilized by gamma radiation, for example disposable bioreactors.Type: GrantFiled: November 12, 2010Date of Patent: August 19, 2014Assignee: Sartorius Stedim Biotech GmbHInventors: Stefan Weisshaar, Michael Bates, Christian Pradel, Volker Limpert
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Patent number: 8792092Abstract: An optoelectronic inclination sensor determines the inclination of a reference plane relative to the horizontal. A sensor body has a liquid layer, the free surface of which represents a horizon that can be inclined relative to the reference plane, forming an optical boundary to the adjacent medium. A light source disposed below the liquid layer emits a light beam onto the boundary. An optical sensor surface below the liquid layer detects the light beam reflected by the boundary. An analysis unit determines the inclination of the reference plane as a function of the amount of light received by the sensor surface. A deflecting element for deflecting or initially totally reflecting the beam is disposed between the source and the liquid layer. The beam is inclined as a result of said deflection or initial total reflection. A second total reflection occurs at the boundary in both the inclined and non-inclined orientation.Type: GrantFiled: March 28, 2011Date of Patent: July 29, 2014Assignee: Sartorius Lab Instruments GmbH & Co. KGInventor: Ralf Müller
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Patent number: 8779388Abstract: An optical sensor is provided with reduced sensitivity toward external light influences, fluorophores, and radiation, more particularly gamma radiation. The sensor is suitable for determining at least one parameter in a medium. The sensor has a matrix that contains a fluorescent dye. The matrix is supported by a transparent substrate and has a precious metal layer on the side facing the medium. The precious metal layer provides protection against photobleaching and radiation. The optical sensor is suitable for implementation in containers and laboratory products that are sterilized by gamma radiation, such as disposable bioreactors.Type: GrantFiled: December 3, 2009Date of Patent: July 15, 2014Assignee: Sartorius Stedim Biotech GmbHInventors: Eberhard Wuenn, Reinhard Baumfalk, Daniel Riechers, Julia Lueders
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Patent number: 8746500Abstract: A mounting assembly is provided including a first piece mounted in a fixed, detachable, and sealed manner, on a rigid, annular collar of a second piece having an end opening. The first piece includes an annular peripheral wall having an inner face configured to contact an outer face of the collar. The first piece includes a transverse wall that can enter the opening, and an annular wall forming a skirt, the inner face of the skirt including a larger diameter part, a smaller diameter part, and an intermediate part configured to contact with conjugated parts of the outer face by clamping. The transverse wall and the skirt form one component and are made of a highly flexible material enabling the first piece to be brought into an intermediate state in which the first piece is enlarged to be removed from the second piece, while retaining elastic deformation.Type: GrantFiled: March 5, 2010Date of Patent: June 10, 2014Assignee: Sartorius Stedim FMT S.A.S.Inventors: Frederic Bernard, Eric Chevalier
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Patent number: 8746515Abstract: A closure for a container has an upper part (1) that can be connected to the container. The upper part (1) has an opening (2) and an outer hollow body (3). An inner hollow body (4) is arranged coaxially in the outer hollow body (3) with an intermediate space therebetween. A lower part (7) in the form of a hollow body can be displaced longitudinally in the intermediate space. A plug (5) is held coaxially in the lower part (7) and opens or closes the opening as the lower part (7) is displaced longitudinally in the intermediate space.Type: GrantFiled: November 17, 2009Date of Patent: June 10, 2014Assignee: Sartorius Stedim Biotech GmbHInventors: Shahmir Fatherazi, Gerhard Greller, Oscar-Werner Reif, Magali Barbaroux, Michael Bates
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Publication number: 20140150924Abstract: A leaktight joining device for ensuring the aseptic transfer of a biopharmaceutical product between a chamber equipped with a removable door and a container equipped with a removable cover, includes: stationary temporary flanging elements, stationary unlocking elements capable of changing the container from an initial locking position to an intermediate unlocking position so as to ensure an aseptic communication between the container and the chamber, stationary locking element capable of changing the container from the intermediate locking position to a final locking position, an annular functional ring gear capable of actuating the stationary unlocking elements and the stationary locking elements of the container.Type: ApplicationFiled: July 12, 2012Publication date: June 5, 2014Applicant: Sartorius Stedim FMT SASInventors: Gaelle Nodin, Jeremy Gibelin
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Publication number: 20140150926Abstract: A container for ensuring the transport and the aseptic transfer of a biopharmaceutical product from or to a closed chamber provided with a leaktight joining device, includes: an annular flange delimiting an opening, a removable cover, built-in elements for locking/unlocking the removable cover and a peripheral envelope. The built-in locking/unlocking elements include a built-in functional locking/unlocking arrangement formed by a through-housing formed in the annular flange and a blind housing formed in the removable cover, and by a pin at an inner radial position and a pin at an outer radial position. The container is capable of being in an initial locking position, in an intermediate unlocking position and in a final locking position owing to the displacements of the pin at an inner radial position and the pin at an outer radial position in the blind hole of the removable cover and in the through-housing of the annular flange.Type: ApplicationFiled: July 12, 2012Publication date: June 5, 2014Applicant: Sartorius Stedim FMT SASInventor: Gaelle Nodin
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Publication number: 20140131399Abstract: The valve includes a female part having a closed, transverse, proximal end wall, and a tubular wall integral with a flange part, a lateral opening being formed on the proximal section of the tubular wall, a male part having a tubular wall forming, on the proximal side, a closing/opening part having an open, transverse, proximal end; the closing/opening part has an external shape and an external dimension that fit the internal shape and internal dimension of the proximal receiving part of the female part. The sealing elements include three ring seals separated from one another in an axial direction, supported by the upper surface of the tubular wall of the male part and engaging with the female part, a proximal seal to the fluid product, a distal seal to external contaminants, and an intermediate seal to the fluid product and to external contaminants between the proximal and distal seals.Type: ApplicationFiled: July 12, 2012Publication date: May 15, 2014Applicant: Sartorius Stedim FMT SASInventors: Florian Blake, Jeremy Gibelin
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Patent number: 8720858Abstract: Diaphragm valve having a valve body with an inlet and an outlet, a sealing membrane, and a connecting piece connecting the sealing membrane to a pressure piece of a drive. The valve body, the sealing membrane and the connecting piece are rigidly connected together to form an interchangeable, sealed valve body unit that can be connected to the drive. The connecting piece is molded on the sealing membrane, and the valve body and the sealing membrane are welded ultrasonically to one another.Type: GrantFiled: September 2, 2009Date of Patent: May 13, 2014Assignees: Sartorius StedimBioteen GmbH, Gemue Gebr. Mueller Apparatelbau GmbH & Co. KGInventors: Lars Böttcher, Jan Schäfer, Kai-Uwe Wolpert, Jürgen Mayer
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Publication number: 20140116941Abstract: The present invention relates to a method for removing biopolymer aggregates and viruses from a fluid. In a first step, the biopolymer aggregates are selectively removed by filtration through a porous, polyamide-comprising shaped body having a native surface. In a second step, the biopolymer aggregate-free fluid is filtered through at least one suitable virus-retentive membrane.Type: ApplicationFiled: April 28, 2012Publication date: May 1, 2014Applicant: Sartorius Stedim Biotech GmbHInventors: Volkmar Thorm, Bjoern Hansmann
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Patent number: 8697436Abstract: The invention relates to a transfer unit for receiving in particular a porous disc-shaped medium from a first treatment device, having an upper part, wherein the upper part comprises a fixing edge that can be connected to an edge of the medium for removing the medium from the first treatment device, wherein the upper part comprises an opening closed by a removable cover, by means of which successive treatments in a further treatment device can be performed. The invention further relates to a method wherein an upper part of a transfer unit is placed on a disc-shaped medium disposed in a first lower part of a first treatment device and exposed to the liquid sample and is connected to an edge of the medium, wherein the upper part is lifted off from the first lower part with the disc-shaped medium connected thereto, and is placed on a further lower part of a corresponding treatment device, and is further processed through an opening in the upper part.Type: GrantFiled: December 2, 2009Date of Patent: April 15, 2014Assignee: Sartorius Stedim Biotech GmbHInventors: Karl Pflanz, Andreas Graus
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Patent number: 8690129Abstract: A disposable mixing vessel comprising a flexible container, a centrally disposed shaft having first and second ends with one or more impellers thereon and a magnetic element associated with a first shaft end, a first flange adapted to rotatably engage the first shaft end and a second flange adapted to rotatably engage the second shaft end.Type: GrantFiled: March 18, 2009Date of Patent: April 8, 2014Assignee: Sartorius Stedim Biotech GmbHInventors: Jens Ludwig, Oscar-Werner Reif, Gerhard Greller, Wolfgang Kahlert, Guenther Pradel, Michael Bates, Magail Barbaroux, Stephane Baud, Isabelle Gay, Sebastian Chaussin
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Patent number: 8690418Abstract: A method of mixing including providing a flexible container which comprises at least two components, assembling the components from outside the flexible container to form a centrally disposed magnetic driven shaft with at least one impeller, whereby the integrity of the flexible container is maintained, filling the flexible container having the centrally disposed magnetic driven shaft with one or more ingredients of the contents to be mixed; engaging a magnetic element of the centrally disposed magnetic driven shaft with an external magnetic drive element; analyzing the contents of the flexible container using at least one sensor or a sampling line on the flexible container; and draining the contents of the flexible container through a drain port at the bottom of the flexible container.Type: GrantFiled: March 18, 2009Date of Patent: April 8, 2014Assignee: Sartorius Stedim Biotech GmbHInventors: Jens Ludwig, Oscar-Werner Reif, Gerhard Greller, Wolfgang Kahlert, Guenther Pradel, Michael Bates, Magail Barbaroux, Stephane Baud, Isabelle Gay, Sebastian Chaussin
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Patent number: D704078Type: GrantFiled: February 2, 2012Date of Patent: May 6, 2014Assignee: Sartorius Weighing Technology GmbHInventors: Alexander Mueller, Sebastian Maier
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Patent number: D713698Type: GrantFiled: June 5, 2013Date of Patent: September 23, 2014Assignee: Sartorius Weighing Technology GmbHInventors: Sebastian Maier, Alexander Mueller, Andreas Poser, Dirk Lamprecht, Thomas Kunz