Abstract: An electron gun for an electron microscope or similar device includes a field emitter cathode having a field emitter protrusion extending from the output surface of a monocrystalline silicon substrate, and electrodes configured to enhance the emission of electrons from a tip portion of the field emitter protrusion to generate a primary electron beam. A contiguous TiN layer is disposed directly on at least the tip portion of the field emitter protrusion using a process that minimizes oxidation and defects in the TiN layer.

Abstract: The present disclosure relates to a nonlinearity compensation circuit for a memristive device. The circuit according to an embodiment includes at least one power source unit to apply an input pulse; a modulation unit connected to the at least one power source unit to adjust a pulse width of an update pulse to be applied to the memristive device; and the memristive device to which the modulated update pulse is applied.

Abstract: Provided herein are enantioselective organocatalytic methods for preparing chiral tetraaryl methanes.

Abstract: A content delivery network processing method includes: obtaining response data from at least one CDN node in response to a network request from a detection end, the response data including information indicating that the network request is successful or failed; calculating the quantity of detection successes and the quantity of detection failures of the detection end corresponding to the at least one CDN node in accordance with the response data; calculating a detection failure rate of the detection end in accordance with the quantity of detection successes and the quantity of detection failures; and comparing at least one of the detection failure rate or the quantity of detection failures with a target threshold, and determining whether the detection end is faulty in accordance with a comparison result.

Abstract: A short-offset transient electromagnetic transmission system, including: an electromagnetic transmitter with transmission power supplies P1, P2, P3, P4, grounding electrodes A, B, C, D, F, and transmission wires LA, LB1, LB2, LC1, LC2, LD1, LD2, LE. The electrodes A and B are connected to the transmission power supply P1 via the wires LA and LB1. The electrodes B and C are connected to the transmission power supply P2 via the wires LB2 and LC1. The electrodes C and D are connected to the transmission power supply P3 via the wires LC2 and LD1. The electrodes D and E are connected to the transmission power supply P4 via the wires LD2 and LE. The wires LA and LB1 are pulled from the electromagnetic transmitter to the electrode B and the wires LD2 and LE are pulled from the electromagnetic transmitter to the electrode D in a twisted-pair manner.

Abstract: Methods for treating a subject with cancer, including administering to the subject an effective amount of an inhibitor of DNAse1L3 and an effective amount of radiation therapy are provided. In some examples, the methods involve enhancing or inducing response of tumor-associated immune cells in the subject, including administering to the subject an effective amount of radiation therapy, and administering to the subject an effective amount of an inhibitor of DNAse1L3, thereby enhancing or inducing the response of tumor-associated immune cells in the subject. In some examples, the tumor-associated immune cells comprise dendritic cells or macrophages.

Abstract: An impeller, for example, a Rushton impeller for a bioreactor system is disclosed. The impeller includes a hub, optionally including a slot, a plurality of blades, and one or more turbulators. The plurality of blades is disposed along a circumferential direction of the hub and spaced apart from each other. Each of the plurality of blades is coupled to at least a portion of a circumference and/or a top surface of the hub. Each blade of the plurality of blades includes a pressure face and a suction face. The one or more turbulators is disposed on at least a portion of the suction face, the pressure face, or both, of a blade of the plurality of blades.

Abstract: The present invention pertains to a projector device for projecting a light beam onto a retina of a human eye, comprising a projector for projecting a light beam from the exterior of a human eye through a pupil of the eye, wherein the projector is configured such that an exit pupil diameter of the light beam is set smaller than an eye pupil diameter of the eye, a corresponding method, and a device comprising such a projector device.

Abstract: The present disclosure provides a method of processing triple data, a method of training a triple data processing model, an electronic device, and a storage medium. A specific implementation solution includes: performing a triple data extraction on text data to obtain a plurality of field data; normalizing the plurality of field data to determine target triple data, wherein the target triple data contains entity data, entity relationship data, and association entity data; and verifying a confidence level of the target triple data to obtain a verification result.

Abstract: A laser light profile measuring device of the present disclosure includes a reflection attenuation part reflecting and attenuating at least part of laser light incident from a first direction in a direction different from the first direction to generate measurement target laser light traveling in the first direction, a capture unit placed on one side of the reflection attenuation part in the first direction and which captures the measurement target laser light, a cooling body covering at least part of the reflection attenuation part and the capture unit in a circumferential direction with respect to the first direction, a refrigerant supply unit forcibly feeding a refrigerant toward the cooling body, and a rotation support part supporting the reflection attenuation part, the cooling body, and the refrigerant supply unit to be rotatable around a rotation axis extending in a horizontal direction.

Abstract: A nitrogen-containing polycyclic fused ring compound of formula I, a pharmaceutical composition thereof, a preparation method therefor and use thereof are related to the field of medicinal chemistry. The compound can be used as a selective and effective RET inhibitor. It has strong inhibitory effect on the RET gatekeeper residue mutant RET V804M, RET solvent-front residue mutant RET G810R and other clinically relevant RET mutants, as well as RET wt. The compound can also inhibit the growth of TT cell line derived from thyroid cancer and Ba/F3 cells transformed with various RET mutants, and induce the death of TT cells.

Abstract: Antibodies that bind to HIV gp120 and neutralize HIV are disclosed. Also disclosed are methods of using such antibodies alone or in combination with other therapeutic agents to treat or prevent HIV infection.

Abstract: An intraocular micro-display (IOMD) system includes an auxiliary head unit. The auxiliary head unit includes a frame for mounting to a head of a user, a scene camera module mounted in or on the frame in a forward-facing orientation, a gaze tracking module disposed in or on the frame and configured to monitor an eye of the user, and an auxiliary controller. The auxiliary controller includes for: acquiring a scene image with the scene camera module, determining a gazing direction of the eye based upon gaze direction data from the gaze tracking module, identifying a sub-portion of the scene image based upon the gazing direction, and wirelessly relaying the sub-portion of the scene image to an IOMD implant within the eye for displaying to a retina of the eye.

Abstract: A reversible stress-responsive material, a preparation method, and a use thereof are provided. The reversible stress-responsive material has the property of real-time reversible force response at room temperature. When used with crosslinked plastic (high Tg) and rubber (low Tg) polymer materials, the reversible stress-responsive material can significantly enhance the mechanical strength and ductility of covalently cross-linked polymers. the triazolinedione (TAD)-indole click chemistry with the force-induced reversible property is used to construct a force-reversible crosslinked polymer material, and such a force-induced reversible crosslinking method can achieve the breakage and re-forming of covalent crosslinking points at room temperature in a solid state without any external stimuli other than the ambient temperature. This room-temperature force-induced reversible C—N covalent crosslinking can be regarded as an innovative approach to designing a high-toughness polymer material.

Abstract: Example biosensor devices having wake-up batteries and associated methods are disclosed. One example device includes a biosensor that has a first electrode for insertion into a subcutaneous layer beneath a patient's skin, and a second electrode coupled to the first electrode for insertion into the subcutaneous layer, and a first battery to apply a voltage across the first and second electrodes, the first battery at least partially electrically decoupled from the electrodes. The device also includes a second battery having an anode material coupled to the first electrode for insertion into the subcutaneous layer, and a portion of the second electrode. The second battery is activatable upon immersion in an electrolytic fluid. The device also includes a wake-up circuit to receive a signal from the second battery and, in response, to electrically couple the first battery to the first and second electrodes to activate the biosensor.

Abstract: The present invention relates to gene isolation and plant improvement, particularly to spotted wilt disease resistance gene RTSW from tobacco and use thereof. Provided are nucleic acid molecules for conferring or enhancing resistance to orthotospoviruses to a plant, and expression cassettes, vectors, host cells, plants and seeds comprising the nucleic acid molecules. The nucleic acid molecules encode RTSW gene products or variants thereof. Additionally provided are methods for conferring or enhancing resistance to orthotospoviruses to a plant, the method comprising introducing the nucleic acid molecules into plant cells.

Abstract: A split gate carrier stored trench bipolar transistor (CSTBT) with current clamping PMOS include a P-type buried layer and a split gate electrode with equal potential to an emitter metal on the basis of the traditional CSTBT, which effectively eliminates the influence of an N-type carrier stored layer on breakdown characteristics of the device through the charge compensation effect, and helps to improve the trade-off relationship between the on-state voltage drop and the turn-off loss. Moreover, the introduction of a parasitic PMOS structure can reduce the saturation current and improve short-circuit safe operating area of the device, reduce the Miller capacitance, and improve the switching speed of the device and reduce the switching loss of the device. In addition, the split gate CSTBT integrating the split gate electrode and gate electrode in the same trench can shorten the distance between PMOS and NMOS channels.

Abstract: A broadband super-Rayleigh speckle correlated imaging spectral camera based on dispersion compensation is provided. The imaging scheme comprises, but is not limited to, a pre-compensation scheme, a post-compensation scheme, or a pre-post joint compensation scheme. The device comprises components such as a pre-imaging module, a light filter, a phase modulation module, a relay imaging module, an area array detector, and a computer. According to the present invention, the super-Rayleigh speckle modulation in a broadband is realized by matchining the dispersion characteristic of the pre-imaging module or the relay imaging module with the phase modulation module, which is applied to the correlated imaging spectral camera, so that the imaging quality of the correlated imaging spectral camera at a low signal-to-noise ratio is improved.

Abstract: Dry eye treatment apparatus and methods which include one or more patches or strips affixed to the skin of the upper and/or lower eyelids to deliver heat or other forms of energy, pressure, drugs, moisture, etc. (alone or in combination) to the one or more meibomian glands contained within the underlying skin. The one or more patches or strips may allow for the subject to blink naturally without restriction from the one or more patches or strips. The one or more patches or strips may be shaped to follow a location of one or more meibomiam glands contained within the underlying region of skin.