Abstract: The present invention provides methods of assessing an individual subject's risk of developing prostate cancer, comprising: a) analyzing a nucleic acid sample obtained from the subject and determining a genotype for the subject at a plurality of biallelic polymorphic loci, wherein each of said plurality has an associated allele and an unassociated allele, wherein the genotype is selected from the group consisting of homozygous for the associated allele, heterozygous, and homozygous for the unassociated allele; and b) calculating a cumulative relative risk (CRR) for the subject based on the genotype determined in step (a). A CRR of greater than 1.00 identifies a subject as having an increased risk of developing prostate cancer and also can identify a subject who is a candidate for early PSA screening, prostate biopsy and/or chemoprevention.

Abstract: A method for assigning a single frequency sub-channel to a plurality of MSs (Mobile Stations) in an OFDM (Orthogonal Frequency Division Multiplexing) system utilizing SDM (Spatial Division Multiplexing) with multiple transmit/receive antennas. In the method, a BS (Base Station) can effectively assign a pilot channel to estimate a downlink channel. The BS divides the single frequency sub-channel into a plurality of spatial channels, and sequentially assigns the plurality of spatial channels to the MSs having the maximum communication capacity, thereby transmitting signals of the MSs through the single frequency sub-channel.

Abstract: Aromatic farnesyl compound and application of a pharmaceutical salt thereof as an inhibitor of ?-glucosidase, dipeptidyl peptidase-4, aldose reductase, protein tyrosine phosphatase-1B or HMG-CoA reductase, or use thereof in preparing medicine and functional healthcare products having a liver protective function and/or for treating and/or preventing type II diabetes, diabetic retinopathy, diabetic foot disease, and hyperlipidemia.

Abstract: An operation method of a controller may include encoding a first data at a first code rate such that the encoded first data is decoded by a first parity check matrix included in a variable code-rate parity check matrix and encoding a second data at a second code-rate such that the encoded second data is decoded by a second parity check matrix included in a variable code-rate parity check matrix.

Abstract: The present invention relates to a novel peptide showing more excellent activities on a glucagon like peptide-1 receptor and a glucagon receptor than native oxyntomodulin, and a composition for the prevention or treatment of obesity comprising the peptide as an active ingredient. Unlike native oxyntomodulin, the novel peptide of the present invention reduces food intake, suppresses gastric emptying, and facilitates lipolysis with reduced side-effects, and also shows excellent receptor-activating effects. Thus, it can be widely used in the treatment of obesity with safety and efficacy.

Abstract: Provided herein are, inter alia, antibodies, antigen-binding antibody fragments, cells, polynucleotides, compositions, kits, and methods relating to the detection of HBV protein X (HBx), e.g., in vitro and in vivo. Included are antibodies and fragments thereof that bind HBx, as well as kits, cells, and compositions comprising such antibodies and fragments.

Abstract: The present disclosure relates generally to compounds (I) which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.

Abstract: A removable system and method for helping position and stabilize implant supported dentures during the healing process after surgery is provided, wherein a removable system comprises a soft tissue supported provisional denture structure configured to help position and stabilize the provisional denture during the transfer of the implant positions to the provisional denture. In the surgical process of providing implant-supported dentures, immediately after the implants are surgically implanted, adhesive is applied to the underside of the provisional denture, and implant connectors are seated on the implants. The provisional denture is seated in the patient's mouth wherein the soft tissue supported provisional denture structure helps stabilize and position the denture. The implant connectors adhere to the adhesive and transfer the implant positions to the provisional denture.

Abstract: The present invention relates compounds of the formula: or pharmaceutically acceptable salts thereof, useful as sodium channel blockers, as well as compositions containing the same, processes for the preparation of the same, and therapeutic methods of use therefore in promoting hydration of mucosal surfaces and the treatment of diseases including cystic fibrosis, chronic obstructive pulmonary disease, asthma, bronchiectasis, acute and chronic bronchitis, emphysema, and pneumonia.

Abstract: A method for fabricating quantum rods includes: preparing a Cd-precursor; preparing a S-precursor and CdSe seeds; preparing a Zn-precursor; mixing the S-precursor and the CdSe seeds with the Cd-precursor in a reaction mixture; adding the Zn-precursor to the reaction mixture; stopping the reaction; and performing a purification process to obtain the quantum rods.

Abstract: Provided is a radiation-tolerant 3D unit MOSFET having at least one selected from a dummy drain (DD), an N-well layer (NW), a deep N-well layer (DNW), and a P+ layer to minimize an influence by a total ionization dose effect and an influence by a single event effect.

Abstract: Systems and methods for hyperspectral imaging are described. In one implementation, a hyperspectral imaging system includes a sample holder configured to hold a sample, an illumination system, and a detection system. The illumination system includes a light source configured to emit excitation light having one or more wavelengths and a diffractive element. The illumination system is configured to structure the excitation light into a predetermined two-dimensional pattern at a conjugate plane of a focal plane in the sample, spectrally disperse the structured excitation light in a first lateral direction, and illuminate the sample in an excitation pattern with the one or more wavelengths dispersed in the first lateral direction.

Abstract: A method and a device for image inpainting on arbitrary surfaces in three-dimensional space are described for inpainting a region of a three-dimensional image utilizing a partial differential equation. The method includes obtaining a three-dimensional image on a surface S in three-dimensional space, and each point of the image includes an image point value and a position vector. The method includes locating an inpainting region D and generating an inpainting mask. The method further includes calculating image point values for points inside the inpainting region D and creating a second three-dimensional image to obtain an inpainted image. The present disclosure solves technical problems that previous methods do not work well on three-dimensional images on arbitrary surfaces and improves image inpainting technology.

Abstract: A TiO2-graphene-silver hybrid nanocomposite and a method of preparing the TiO2-graphene-silver hybrid nanocomposite is disclosed. The TiO2-graphene-silver hybrid nanocomposite at an average particle size ranging from 12-15 nanometers and having a surface area of 140.5 m2/g includes titanium oxide, graphene oxide and silver, the silver ranging from about 2 weight % to 10 weight %. The method of preparation includes introducing sol gel to a microwave irradiation to prepare an irradiated sample of TiO2-graphene oxide sample, wherein the sol gel includes TiO2 containing gel along with graphene containing sol, followed by adding AgNO3 solution to the TiO2-graphene oxide sample for preparing a TiO2-graphene-silver hybrid suspension. The TiO2-graphene-silver hybrid suspension undergoes microwave irradiation to prepare dried TiO2-graphene-silver hybrid composite.

Abstract: An image sensor and a method of manufacturing the image sensor are provided. The image sensor includes a block layer including an absorption layer and a transparent layer, a lens element located below the block layer, and a sensing element located to face the lens element.

Abstract: The invention is related to safety systems for nuclear power plants (NPP) which can be used in various operational modes, including emergency mode, and is aimed at controlling air flows inside NPP containment buildings. NPP containment building separation system dividing the NPP containment building into isolated rooms. It includes the containment building separation shutters located in the circular gap which divides the containment building rooms and the containment building walls; an air supply unit connected to a manifold ring which, in turn, is connected to the air-inflated shutters designed to ensure insulation of the airspace inside the containment building rooms when inflated and at connecting the airspace when deflated. In emergency mode the air supply to the air-inflated shutters is terminated, the shutters get deflated and fully open the circular gap which ensures convection process throughout the whole area of containment building.

Abstract: The present invention provides a method for the functionalization of a polymeric surface with a protein by physical adsorption. The method enables a membrane spanning protein to be used as an anchor for proteins and/or peptides for display. Also provided are polymeric substrates for protein or peptide display, and related kits and methods of use.

Abstract: Provided herein are keratin compositions (e.g., keratin gels, scaffolds, particulates, and the like) including a compound of interest, useful for release and/or delivery of the compound of interest (e.g., in vivo or in vitro). In some embodiments, the composition is a composition formulated for controlled release of the compound of interest.

Abstract: Methods, systems, and media for dynamically detecting mobile environment information are provided.

Abstract: Azepine derivatives acting on 5-HT7 receptors and pharmaceutically acceptable salts thereof are disclosed. The azepine derivatives and the pharmaceutically acceptable salts thereof have high binding affinities for and high antagonistic activities on 5-HT7 receptors. Due to these advantages, the azepine derivatives and the pharmaceutically acceptable salts thereof can be applied to therapeutic or prophylactic agents for central nervous system diseases, such as depression, migraine, anxiety, pain, inflammatory pain, neuropathic pain, body temperature dysregulation, biorhythm dysregulation, sleep disturbance, and smooth muscle diseases where 5-HT7 receptors antagonistic activity is required.