Patents Assigned to Sciences
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Patent number: 10532983Abstract: Disclosed are derivative compounds of ELQ-300 that include an ester at position 4. These compounds have enhanced properties relative to ELQ-300. Also disclosed are pharmaceutical compositions comprising the compounds and methods of treating and preventing malaria infections involving administering the pharmaceutical compositions to the subject.Type: GrantFiled: July 20, 2016Date of Patent: January 14, 2020Assignee: Oregon Health & Science UniversityInventors: Michael Riscoe, Aaron Nilsen, Galen Miley, Rolf Winter, Sovitj Pou, Jane Xu Kelly, Rozalia Dodean
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Patent number: 10532854Abstract: Disclosed is a drum stacking assembly 100. The assembly 100 comprises a first set of plurality of drums 108a and a second set of plurality of drums 108b, positioned relative amongst each other via a first connector 101 and a second connector respectively. Further, said assembly 100 comprises a pallet 109, wherein a top surface of the pallet 109 comprises a plurality of support shells 601 further comprising at least a plurality of ribs 602 adapted to support the first set of drums 108a. An outer reinforcing ring of the bottom surface of the first set of drums 108a is guided in the plurality of ribs 602. Further, a bottom surface of the pallet 109 comprises a plurality of grooves 202 further comprising at least a plurality of indentations 603 adapted to engage an outer reinforcing ring 301 of the upper surface of the second set of drums 108b.Type: GrantFiled: October 3, 2017Date of Patent: January 14, 2020Assignee: Genex Science and Technologies Pvt. Ltd.Inventor: Anil Jain
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Patent number: 10532043Abstract: Human therapeutic treatment compositions comprise at least two of a curcumin component, a harmine component, and an isovanillin component, and preferably all three in combination. The agents are effective for the treatment of human conditions, especially human cancers.Type: GrantFiled: August 15, 2019Date of Patent: January 14, 2020Assignee: Ankh Life Sciences LimitedInventors: Gene H. Zaid, Thomas W. Burgoyne
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Patent number: 10535514Abstract: Provided are methods of sealing open pores of a surface of a porous dielectric material using an initiated chemical vapor deposition (iCVD) process. In one example method of sealing open pores, since the polymer thin film having a significantly thin thickness may be formed by a solvent-free vapor deposition method without plasma treatment, it is possible to minimize deterioration of characteristics of the dielectric material vulnerable to plasma and a chemical solution.Type: GrantFiled: August 25, 2016Date of Patent: January 14, 2020Assignees: Korea Advanced Institute of Science and Technology, Lam Research CorporationInventors: Byung Jin Cho, Sung Gap Im, Seong Jun Yoon, Kwanyong Pak, Hyungsuk Alexander Yoon
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Patent number: 10535444Abstract: Provided is a composite carbon material including a substrate and a graphene oxide. The graphene oxide accounts for about 5 wt % to 60 wt % based on a total weight of the substrate and the graphene oxide. A method of preparing a composite carbon material is further provided. The prepared composite carbon material has excellent hydrophilic property, flexibility, electrical conductivity and dispersity.Type: GrantFiled: December 10, 2015Date of Patent: January 14, 2020Assignee: National Taiwan University of Science and TechnologyInventors: Wei-Hung Chiang, Yen-Sheng Li
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Patent number: 10533183Abstract: The invention relates to a method for producing eicosapentanoic acid, docosapentanoic acid and/or docohexanoic acid in transgenic plants. According to said method, the plant is provided with at least one nucleic acid sequence coding for a polypeptide with a ?6 desaturase activity, at least one nucleic acid sequence coding for a polypeptide with a ?6 elongase activity, at least one nucleic acid sequence coding for a polypeptide with a ?5 desaturase activity, and at least one nucleic acid sequence coding for a polypeptide with a ?5 elongase activity, the nucleic acid sequence coding for a polypeptide with a ?5 elongase activity being modified in relation to the nucleic acid sequence in the organism from which the sequence originates, such that it is adapted to the codon use in at least one type of plant. For the production of docosahexanoic acid, at least one nucleic acid sequence coding for a polypeptide with a ?4 desaturase activity is also introduced into the plant.Type: GrantFiled: April 1, 2019Date of Patent: January 14, 2020Assignee: BASF Plant Science GmbHInventors: Petra Cirpus, Jörg Bauer, Xiao Qiu, Guohai Wu, Bifang Cheng, Martin Truksa, Tom Wetjen
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Patent number: 10533231Abstract: The invention relates to establishment of a series of artificial luciferases based on artificial amino acid sequences extracted by amino acid alignment of copepod-derived luciferase sequences in a database based on amino acid similarity. The invention provides high luminescence intensity, high luminescence stability, and a spectrum with increased wavelength as luminescence characteristics. A series of artificial luciferases (ALuc) was established. The group of ALucs has superior luminescence characteristics, such as an increase in luminescence intensity, an increase in luminescence stability, or an increase in wavelength of the luminescence spectrum, which were not obtained before. Further, by using the artificial luciferases (ALuc) of the invention, it is possible to provide a novel, superior bioassay system, such as a bioluminescent probe, two-hybrid assay, a luminescent capsule, or the like having improved measurement function.Type: GrantFiled: September 18, 2013Date of Patent: January 14, 2020Assignee: National Institute of Advanced Industrial Science and TechnologyInventors: Sung Bae Kim, Masaki Torimura, Hiroaki Tao, Tetsuya Nakazato
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Patent number: 10532596Abstract: A plasmonic structure having an identifier pattern indicating a genuine product for preventing counterfeiting, falsification or reuse, includes a metal layer; a photoconversion pattern layer including a plurality of photoconverting nanoparticles disposed in a pattern on and in direct contact with the metal layer; a metal pattern layer including a plurality of metal particles disposed in a pattern on and in direct contact with the photoconversion pattern layer; and an adhesive film disposed on the metal pattern layer. An identifier pattern indicating a genuine product is easily identified even by visual inspection after irradiation with infrared light irradiation. The plasmonic structure is fundamentally impossible to re-assemble after deformation of the plasmonic structure caused by disassembly of a product or packaging container, thereby preventing counterfeiting, falsification or reuse.Type: GrantFiled: September 8, 2017Date of Patent: January 14, 2020Assignee: Korea Institute of Science and TechnologyInventors: Hyungduk Ko, Kisun Park, Ho Seong Jang, Il Ki Han
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Patent number: 10532090Abstract: The present invention provides a vaccine composition comprising: (i) an adjuvant; and (ii) at least one fusion peptide conjugated to a carrier protein, wherein the carrier protein is the diphtheria toxin variant CRM-197 (GenBank Accession No. 1007216A) and wherein the at least one fusion peptide comprises two or more non-contiguous B cell epitopes of Her2/neu selected from the group consisting of SEQ ID Nos:1-7 and 15-60 and amino acid sequences that have at least 85% identity to any of the foregoing. The present invention also extends to pharmaceutical compositions and methods of using the vaccine and/or pharmaceutical compositions, as herein described, for the treatment or prevention of a cancer characterised by the expression or over-expression of Her2/neu in a patient in need thereof.Type: GrantFiled: April 15, 2016Date of Patent: January 14, 2020Assignee: Biolife Science QLD LimitedInventor: Ursula Wiedermann
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Patent number: 10532465Abstract: A handheld tool includes a handle for holding by a user, an attachment arm extending from the handle that is configured to connect to a user-assistive device, a first inertial measurement unit (“IMU”) mounted to the attachment arm to acquire measurements of one or more of a motion or an orientation of the user-assistive device and to generate feedback data indicative of the measurements, an actuator assembly coupled to manipulate the user-assistive device via the attachment arm in at least two orthogonal dimensions, and a motion control system coupled to receive the feedback data from the first IMU and coupled to provide commands to the actuator assembly to provide auto-leveling of the user-assistive device to a frame of reference while the user manipulates the handheld tool.Type: GrantFiled: February 16, 2017Date of Patent: January 14, 2020Assignee: Verily Life Sciences LLCInventors: Anupam J. Pathak, Michael M. Allen
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Patent number: 10532972Abstract: Dibasic esters (diesters) and their use in plasticizer compositions are generally disclosed. In some embodiments, the diesters are branched-chain esters of long-chain alkanedioic acids, such as octadecanedioic acid. In some embodiments, such plasticizer compositions are used to increase the plasticity of a polymer resin, such as a vinyl chloride resin or poly vinyl butyral. In some other embodiments, such plasticizer compositions are used to lower the glass transition temperature of a polymer resin. In some embodiments, at least a portion of the plasticizer is derived from a renewable source, such as a natural oil.Type: GrantFiled: April 28, 2017Date of Patent: January 14, 2020Assignee: Elevance Renewable Sciences, Inc.Inventors: Tessa Pals, Steven A. Cohen, Thomas E. Snead, Allyson Beuhler, Paul A. Bertin
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Patent number: 10534660Abstract: The present invention provides a response message processing method, apparatus, and system, and relates to the communications field. The method includes: sending, according to a device identifier sent by a request device, a query request to a destination device corresponding to the device identifier, so that the destination device returns a response message according to the query request; generating substitution data when an error occurs in the response message, where the substitution data is associated with resource data requested by the query request and is used to substitute for the resource data requested by the query request; and sending response substitution information to the request device, where the response substitution information includes the substitution data and the device identifier.Type: GrantFiled: July 7, 2017Date of Patent: January 14, 2020Assignees: Huawei Technologies Co., Ltd., University of Electronic Science and Technology of ChinaInventors: Yang Xu, Yarui Wang, Yan Li
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Publication number: 20200010846Abstract: The present invention provides the specific expression promoters in rice and the application. The present invention applies the promoter in the plant genetic engineering. The sequence of the promoter provided in the present invention is composed of the nucleotide sequence shown in SEQ ID No. 11; the nucleotide sequence shown in SEQ ID No. 2; Or the nucleotide sequence shown in SEQ ID No. 3.Type: ApplicationFiled: March 14, 2019Publication date: January 9, 2020Applicant: Rice Research Institute, Anhui Academy of Agricultural SciencesInventors: Pengcheng Wei, Juan Li, Jianbo Yang, Hao Li, Ruiying Qin, Rongfang Xu
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Publication number: 20200011295Abstract: Provided are a method and a system for controlling wind turbine shutdown. The method includes: obtaining, according to a preset sampling period, a grid voltage for a wind turbine, and sending the obtained grid voltage to an converter controller; determining, by the converter controller and based on the grid voltage, an operating condition of a power grid is power outage of power grid; sending, in a case that the power outage of power grid is determined, a signal indicating power outage of power grid to a main controller of a main control system of the wind turbine; and controlling, by the main controller in a case that the signal indicating power outage of power grid is received, a pitch system to perform a variable-rate feathering.Type: ApplicationFiled: April 10, 2018Publication date: January 9, 2020Applicant: Xinjiang Goldwind Science & Technology Co., Ltd.Inventors: Lei ZHANG, Zhiqiang YANG, Lei MA
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Publication number: 20200009324Abstract: Systems and methods for triggering a drug injection device are disclosed. One disclosed system for injecting a substance into a patient includes: a chamber comprising a propellant; a light source mechanically coupled to the chamber, wherein energy from the light source ignites the propellant; and a power source electrically coupled to the light source via a control circuit, wherein the control circuit applies power to activate the light source.Type: ApplicationFiled: June 24, 2019Publication date: January 9, 2020Applicant: Verily Life Sciences LLCInventors: Daniel Barrows, Grant Smith
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Publication number: 20200011839Abstract: In a method of inspecting a structure, a first ultrasonic signal generated from a target structure by a first laser beam is received. The first ultrasonic signal is generated by providing the first laser beam generated from a first excitation unit to the target structure. A second ultrasonic signal generated from the target structure by a second laser beam different from the first laser beam is received. The second ultrasonic signal is generated by providing the second laser beam generated from a second excitation unit to the target structure. A third ultrasonic signal generated from the target structure by the first and second laser beams is received. The third ultrasonic signal is generated by simultaneously providing the first and second laser beams to the target structure. It is determined whether the target structure is damaged based on first, second and third ultrasonic frequency spectra that are obtained by converting the first, second and third ultrasonic signals, respectively.Type: ApplicationFiled: May 31, 2019Publication date: January 9, 2020Applicant: Korea Advanced Institute of Science and TechnologyInventors: Hoon Sohn, Peipei Liu, Jinho Jang
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Publication number: 20200010792Abstract: A storage assembly for storing a plurality of specimens includes a frame, a plurality of modular storage units for perfusion and/or incubation of one or more specimens removably coupled to the frame, a sample transfer apparatus configured to retrieve a specimen holder from a chosen modular storage unit of the plurality of modular storage units, and a control unit communicatively coupled to the sample transfer apparatus. The control unit is configured to cause the sample transfer apparatus to retrieve a specimen from a modular storage unit of the plurality of modular storage units and deliver the specimen to a delivery position.Type: ApplicationFiled: July 3, 2019Publication date: January 9, 2020Applicant: Advanced Solutions Life Sciences, LLCInventors: Michael W. Golway, Scott Douglas Cambron
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Publication number: 20200010496Abstract: The invention provides a method for preparing a technetium-99m tricarbonyl intermediate. The method comprises reacting a manganese carbonyl compound used as a carbon monoxide source with pertechnetate and water to obtain the technetium-99m tricarbonyl intermediate. The method for preparing a technetium-99m tricarbonyl intermediate in an embodiment of the invention can complete the preparation of the intermediate at atmospheric pressure and room temperature. The method is easy to operate, uses easily obtained raw materials, has a high labeling yield, and can be used to prepare various types of technetium tricarbonyl labeled probes.Type: ApplicationFiled: December 28, 2016Publication date: January 9, 2020Applicant: Institute of High Energy Physics, Chinese Academy of SciencesInventors: Wenjiang Yang, Yu Liu, Jingquan Xue, Yanhua Zhang
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Publication number: 20200009272Abstract: Provided are photoacoustic imaging contrast agents that include at least one radiation-absorbing component comprising a bacteriochlorin, a metallobacteriochlorin, a derivative thereof, or a combination thereof. Also provided are methods for using the disclosed photoacoustic imaging contrast agents either singly or in combination for generating an image of a volume, optionally a subject or a body part, cell, tissue, or organ thereof. Further provided are compositions and methods for multiplex photoacoustic imaging of a volume, optionally a subject or a body part, cell, tissue, or organ thereof using photoacoustic imaging contrast agents that include a plurality of the presently disclosed bacteriochlorins, metallobacteriochlorins, and/or derivatives thereof simultaneously.Type: ApplicationFiled: February 2, 2018Publication date: January 9, 2020Applicant: NIRvana Sciences Inc.Inventors: James Bruce Pitner, Rajalekha Manjakuppam Rajamahendiran, Russell D. Thomas
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Patent number: D872659Type: GrantFiled: May 22, 2017Date of Patent: January 14, 2020Assignees: Warner Science Applications Corp., Paramount Automotive Restyling Inc.Inventor: Mingfa Yang