Abstract: A chromatography column including: a tubular housing; a first end unit removably connected to a first end of the tubular housing; a second end unit removably connected to a second end of the tubular housing; an adaptor assembly movable within said tubular housing; an adaptor rod connected to said adaptor assembly, which adaptor rod is arranged to extend through an opening in the first end unit; a filter removably connected to the adaptor assembly; and a frame connected to said tubular housing for supporting the column on a floor. At least an actuating means is arranged on the frame, so that the column can be lifted and lowered in a substantially vertical direction.

Abstract: A capturing hook for engaging a cable during capture and release of an aerial vehicle may comprise a first and second gate pivotally supported at their first ends by a base portion and each being movable between a closed position and an open position, but spring-biased to the closed position. The capturing hook may further include a latch device comprising a movable locking part biased by a return spring to a locked position to lock the second gate in the closed position.

Abstract: The present application provides the compounds of formula (J), or pharmaceutically acceptable salts, isomers, tautomer, or a mixture thereof, wherein X, Y, Z, n, m?, A?, R1, R2, and R3 are described herein. The compounds are inhibitors to the activities of phosphatidylinositol 3-kinase (PI3K) and are useful for treating conditions mediated by one or more PI3K isoforms. The present application further provides pharmaceutical compositions that include a compound of formula (I), or pharmaceutically acceptable salts, isomers, tautomer, or mixture thereof, and methods of using these compounds and compositions for treating conditions mediated by one or more PI3K isoforms.

Abstract: An ICP emission spectrophotometer includes an inductively coupled plasma device, a spectroscope, and a computer. The spectroscope includes an incidence window, an incidence side slit, a diffraction grating, an emission window, an emission side slit, and a detector. Measurement conditions including diffraction condition and a measurement result are displayed on a display device. In a case where there are a plurality of diffraction conditions each including a combination of a diffraction grating and a diffraction order for measuring desired diffracted light, comparison information including at least an intensity and a resolution of emitted light in the diffraction condition is displayed on the display device. A measurer selects diffraction conditions in which resolution is higher from among the diffraction conditions, and selects a diffraction condition in which an intensity is obtained from among the selected diffraction conditions.

Abstract: Disclosed herein are methods of treating a hepatitis E viral infection comprising administering to a human subject in need thereof a therapeutically effective amount of the compound sofosbuvir, also known as (S)-isopropyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate. Some methods further comprise concomitantly administering ribavirin to the subject. In some methods, the treatment is ribavirin-free. In some methods, the subject is immunocompromised. In some methods, the subject is pregnant.

Abstract: An electrode additive comprising an electrochemically active material in a form of one-dimensional molecular chain is disclosed wherein the electrochemically active material is contained inside a nanotube-formed conductive shell material. An electrode comprising said electrode additive, and the uses of said electrode additive and said electrode are also disclosed.

Abstract: Disclosed is a ball bearing including an inner ring and an outer ring spaced apart from each other, each being rotatable, a cage part including a first cage and a second cage rotatably installed between the inner ring and the outer ring, and having ball receiving part formed along circumferential direction, ball installed in the ball receiving part, and rotating with the cage part as at least one of the inner ring and the outer ring rotates, and magnet which provides a magnetic force to the ball, wherein the first cage has a first seating part which is formed between the ball receiving parts, and on which one side of the magnet is placed, and the second cage has a second seating part which is connected to the first seating part, and on which the other side of the magnet is placed.

Abstract: Methods, systems, and media for identifying automatically refreshed advertisements are provided. In some embodiments, a method for modifying advertisement spending is provided, the method comprising: receiving advertisement delivery information associated with a plurality of advertisements displayed on a web page; generating a distribution of an amount of time that the plurality of advertisements were displayed on the web page using the advertisement delivery information; identifying a deviation in the generated distribution; determining whether the deviation correlates to an automatic refresh command performed by one or more browser applications; and providing an indication corresponding to the plurality of advertisements that were displayed on the web page in response to the automatic refresh command based on the determination.

Abstract: A method for detecting cancer in an individual comprising detecting a deletion in the nucleic acid sequence between residues 10743 and 14125 in mitochondrial DNA, obtaining a biological sample from the individual, extracting the mitochondrial DNA (mtDNA) from the sample, quantifying the amount of mtDNA in the sample having a deletion in the nucleic acid sequence between residues 10743 and 14125 of the mtDNA genome, and comparing the amount of mtDNA in the sample having the deletion to at least one known reference sample.

Abstract: A process for assessing risk that administration of a substance will suppress immune competence in a population of subjects is provided. Such a substance may be a substance related to, contained in or derived from a tobacco product or, more generally, a substance concerning which it is desired to assess risk of administration of the substance.

Abstract: A cognitive training method has a step of obtaining sensor data of a subject during a memory exercise which in turn determines whether the sensor data includes predetermined information indicative of cognitive functions used for remembering. The step of advancing the memory exercise is carried out when it is determined that the sensor data includes predetermined information indicative of cognitive functions used for remembering. The step of calculating an objective cognitive assessment of the subject is carried out when the memory exercise is completed and cognitive training is measured at least partially in response to the advancing of the memory exercise. The fact that an objective cognitive assessment is calculated provides a method of using an autodidactic cognitive training device.

Abstract: Provided is a compound that comprises the structure: where SIG is a signaling molecule and R3 is a formyl, a succinyl, a methyl succinyl, or a myristoyl. Also provided is a kit is provided that comprises the above compound, with instructions for determining the presence of the enzyme. Additionally, a method is provided for determining whether a sample has an enzyme that removes a succinyl, a methyl succinyl, a formyl, or a myristoyl moiety from an ?-amino of a lysine. Also provided is a method of determining whether a molecule inhibits an enzyme that removes a succinyl, a methyl succinyl, a formyl, or a myristoyl moiety from an ?-amino of a lysine.

Abstract: The present invention is directed to a solar-powered aircraft comprising a fixed wing panel, a motor driven propeller, a plurality of secondary wing panels, and a tail assembly having a first tail panel and a second tail panel. Each secondary wing panel being configured to rotate about a first longitudinal pivot axis extending from a distal end of the fixed wing panel through a central transverse portion of the secondary wing panel. The secondary wing panels may comprise an array of solar panels on its surface. The first tail panel comprises a second array of solar panels located on a surface of the first tail panel, the first tail panel being configured to rotate about a second longitudinal pivot axis through a central transverse portion of the first tail panel.

Abstract: The present invention concerns liquid nutritional compositions comprising at least about 20% (w/w) total protein, and wherein the total protein essentially comprises whey protein and casein. The Compositions are useful for promoting muscle growth in a subject.

Abstract: An asymmetric debris-flow discharge channel is provided. The debris-flow discharge channel has a main drainage channel for discharging a debris flow and an auxiliary channel provided outside of the main drainage channel. The side walls of the auxiliary channel are integrated with the side walls of the main drainage channel or provided outside of the side walls of the main drainage channel. The debris-flow discharge channel also has a break section integrated into a side wall of the auxiliary channel. The top width of the break section is equal to the top width of the auxiliary channel A method for designing and building the asymmetric debris-flow discharge channel is also provided, which provides a lower initial cost, higher safety performance, and a lower maintenance cost at the operating stage.

Abstract: A UV radiation detector includes: a diode including a substrate having a first side and a second side, the first side and the second side being located on opposing faces of the substrate, an active layer including rocksalt phase crystalline structure CaS disposed on the first side of the substrate, an electrical contact disposed on the second side of the substrate, and a semi-transparent conducting layer disposed on the active layer; and a circuit connecting the semi-transparent conducting layer and the electrical contact. The UV radiation detector detects radiation having a wavelength between 200 and 280 nm.

Abstract: The present invention relates to a combination of pure 5-HT6 receptor antagonist, acetylcholinesterase inhibitor and NMDA receptor antagonist. Also, the present invention provides pure 5-HT6 receptor (5-HT6R) antagonists, or the pharmaceutically acceptable salt(s) thereof in combination with or as adjunct to acetylcholinesterase inhibitor and N-Methyl-D-aspartate (NMDA) receptor antagonist and their use in the treatment of cognitive disorders. The invention further provides the pharmaceutical composition containing the said combination.

Abstract: The present invention relates to a method for preparing a metal catalyst (Ni, Co, etc.)-supported porous silicon carbide structure having meso- to macro-sized pores, high porosity and superior mechanical properties. Unlike the existing method wherein a porous silicon carbide structure is prepared and then the metal catalyst is infiltrated therein, the preparation of the porous silicon carbide structure and the supporting of the metal catalyst occur at the same time by the mixing metal catalyst material and starting materials. As a result, the metal catalyst is distributed uniformly in the porous silicon carbide structure and it is possible to locate a desired amount of the metal catalyst inside the porous silicon carbide structure.

Abstract: Disclosed in the present invention is a non-invasive detection method for screening for a well-developed blastocyst. A DNA methylation profile of a few of trophoblastic cells in a blastocyst is detected, and the average methylation level and the methylation pattern of embryos identified as having a good morphology in Gardner morphological blastocyst grading process are used as the standard for screening for well-developed blastocysts. The nearer the methylation level of the trophoblastic cells of the blastocyst to be tested approaches the methylation level or state of the good embryo, the better the embryo development is and the higher the suitability for being implanted into a maternal subject is. Furthermore, results of methylation sequencing may be analyzed to determine whether a chromosome is abnormal, so as to directly exclude chromosome-abnormal embryos.

Abstract: A meta-solid-state battery includes a first layer disposed on a first current collector, a second layer disposed on a second current collector, and third layer disposed between the first layer and the second layer. The first layer and the second layer are the cathode and anode electrodes. The third layer includes a first meta-solid-state electrolyte material. Each of the cathode and anode electrodes contain: an active material in an amount ranging from approximately 70% to 99.98% by weight, a carbon additive in an amount ranging from approximately 0.010% to 20% by weight, and a second meta-solid-state electrolyte material in an amount ranging from approximately 0.010% to 10% by weight. The first and second meta-solid-state electrolyte material include a gel polymer.