Patents Assigned to Sciences
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Patent number: 10298906Abstract: A camera attachment apparatus for attaching to a mobile computing device having an integrated camera includes a house, a slide plate, an aperture, and an illumination system. The housing has a shape to mount on the mobile computing device. The slide plate is disposed within the housing and has a stowed position and a deployed position. The aperture is disposed in the slide plate. The illumination system is disposed on the slide plate. The slide plate is configured to align the aperture over the integrated camera when moved to the deployed position and does not obstruct the integrated camera in the stowed position.Type: GrantFiled: September 7, 2016Date of Patent: May 21, 2019Assignee: Verily Life Sciences LLCInventors: Peter Smith, Eric Peeters, Benjamin Krasnow
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Patent number: 10294419Abstract: [Problem] To provide highly heat-resistant and radiation-resistant radiation measuring equipment. [Solution] Provided are a charged particle radiation measuring method and a charged particle radiation measuring device using a scintillator comprising a phosphor in which the main component is a SiAlON phosphor.Type: GrantFiled: August 25, 2016Date of Patent: May 21, 2019Assignees: Denka Company Limited, National University Corporation Gunma University, National Institutes For Quantum And Radiological Science And TechnologyInventors: Wataru Kada, Kenta Miura, Osamu Hanaizumi, Tomihiro Kamiya, Takahiro Satoh, Junichi Susaki, Suzuya Yamada
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Patent number: 10294210Abstract: This invention relates to malienated derivatives made from maleic anhydride, functionalized monomers, and one or more additional reagents, e.g., an oxygen-containing reagent (e.g., alcohol, polyol), a nitrogen-containing reagent (e.g., amine, polyamine, aminoalcohol), a metal and/or a metal compound. The invention relates to lubricants, functional fluids, fuels, dispersants, detergents and functional compositions (e.g., cleaning solutions, food compositions, etc.).Type: GrantFiled: August 17, 2017Date of Patent: May 21, 2019Assignee: Elevance Renewable Sciences, Inc.Inventors: Stephen A. Di Biase, Syed Q. A. Rizvi, Georgeta Hategan
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Patent number: 10294234Abstract: The invention provides a compound of Formula I: or a pharmaceutically acceptable salt thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of Formula I, processes for preparing compounds of Formula I, therapeutic methods for treating the proliferation of the HIV virus, treating AIDS or delaying the onset of AIDS symptoms in a mammal using compounds of Formula I.Type: GrantFiled: February 5, 2018Date of Patent: May 21, 2019Assignee: Gilead Sciences, Inc.Inventors: Elizabeth M. Bacon, Elbert Chin, Jeromy J. Cottell, Ashley Anne Katana, Darryl Kato, John O. Link, Nathan Shapiro, Teresa Alejandra Trejo Martin, Zheng-Yu Yang
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Patent number: 10296912Abstract: Systems and methods include: implementing a first machine learning model to generate an output of a global digital threat score for an online activity based on an input of the collected digital event data; implementing a second machine learning model that generates a category inference of a category of digital fraud or a category of digital abuse from a plurality of digital fraud or digital abuse categories; selecting a third machine learning model from an ensemble of digital fraud or digital abuse machine learning models based on the category inference generated by the second machine learning model, wherein the ensemble of digital fraud or digital abuse machine learning models comprise a plurality of disparate digital fraud or digital abuse category-specific machine learning models; and implementing the selected third machine learning model to generate a digital fraud or digital abuse category-specific threat score based on the digital event data.Type: GrantFiled: September 21, 2018Date of Patent: May 21, 2019Assignee: Sift Science, Inc.Inventors: Fred Sadaghiani, Alex Paino, Jacob Burnim, Keren Gu, Gary Lee, Noah Grant, Eugenia Ho, Doug Beeferman
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Patent number: 10296999Abstract: A method embeds a watermark image into a host image with adaptive rectangular partition and Lower Upper (LU) decomposition such that a watermarked image is generated with improved computational complexity. The method divides a host image into an Red (R) component, a Green (G) component, and a Blue (B) component, and divides each component of the R, G, and B components into a plurality of M×M size blocks, and partitions each of the plurality of M×M size blocks into a plurality of non-overlapping blocks with adaptive rectangular partition. The method selects a plurality of embedding blocks from the plurality of M×M size blocks for each component of the R, G, and B components of the host image to embed watermark information such that the watermarked image is generated.Type: GrantFiled: February 13, 2017Date of Patent: May 21, 2019Assignee: Macau University of Science and TechnologyInventor: Zhanchuan Cai
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Patent number: 10293083Abstract: The present invention relates to hydrogels comprising a plurality of amphiphilic peptides and/or peptoids capable of self-assembling into three-dimensional macromolecular nanofibrous networks, which entrap water and form said hydrogels, wherein at least a portion of said plurality of amphiphilic peptides is chemically cross-linked. The present invention further relates to methods for preparing such hydrogels and to various uses of such hydrogels, e.g. as cell culture substrates, for drug and gene delivery, as wound dressing, as an implant, as an injectable agent that gels in situ, in pharmaceutical or cosmetic compositions, in regenerative medicine, in tissue engineering and tissue regeneration, or in electronic devices. It also relates to a method of tissue regeneration or tissue replacement using a hydrogel in accordance with the present invention.Type: GrantFiled: January 4, 2017Date of Patent: May 21, 2019Assignee: Agency for Science, Technology and ResearchInventors: Charlotte Hauser, Wei Yang Seow
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Patent number: 10294217Abstract: The present invention relates to compound of formula (I), or stereoisomers and pharmaceutically acceptable salts as muscarinic M1 receptor positive allosteric modulators. This invention also relates to methods of making such compounds and pharmaceutical compositions comprising such compounds. The compounds of this invention are useful in the treatment of various disorders that are related to muscarinic M1 receptor.Type: GrantFiled: July 19, 2016Date of Patent: May 21, 2019Assignee: Suven Life Sciences LimitedInventors: Ramakrishna Nirogi, Anil Karbhari Shinde, Abdul Rasheed Mohammed, Ramkumar Subramanian, Vijay Sidram Benade, Gopinadh Bhyrapuneni, Venkateswarlu Jasti
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Patent number: 10292608Abstract: Disclosed methods and systems may be operable to obtain non-contact diagnostic information about movements of scattering objects such as fluids in subsurface vasculature in tissue. As an example, a method may include causing a light source to illuminate the tissue with at least a first portion of the emitted light and illuminate an optical modulator with at least a second portion of the emitted light. The second portion of the emitted light may be modulated by the optical modulator. An offset source is configured to provide an offset frequency signal. An image sensor may receive optical information from the sample. A heterodyne signal based on the reference frequency signal and the offset frequency signal may be used as a gain input of each detector element of the image sensor. Based on the received information, a movement of a portion of the sample may be determined.Type: GrantFiled: November 24, 2015Date of Patent: May 21, 2019Assignee: Verily Life Sciences LLCInventor: Andrew Homyk
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Patent number: 10294529Abstract: The present application relates to the field of cancer, particularly to mismatch repair (MMR?) deficient tumors. New markers are presented herein that have a high sensitivity to detect whether a tumor is mismatch repair deficient or not. The markers are particularly mutations in microsatellite regions. Accordingly, methods are provided for diagnosing microsatellite instability of a tumor, comprising determining the presence of these markers. Further, kits are provided to detect the presence of these markers (or subsets thereof) in a sample.Type: GrantFiled: April 10, 2013Date of Patent: May 21, 2019Assignees: Life Sciences Research Partners VZW, VIB VZWInventor: Diether Lambrechts
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Patent number: 10294257Abstract: Methods of preparing ruthenium carbene complex precursors are disclosed herein. In some embodiments, the methods include reacting a ruthenium refinery salt with an L-type ligand and a reducing agent to form the ruthenium carbene complex precursor. Methods of preparing a ruthenium vinylcarbene complex are also disclosed. In some embodiments, preparing a ruthenium carbene complex includes converting a ruthenium carbene complex precursor into a ruthenium carbene complex having a structure (PR1R2R3)2Cl2Ru?CH—R4, wherein R1, R2, R3, and R4 are defined herein.Type: GrantFiled: October 26, 2016Date of Patent: May 21, 2019Assignee: Elevance Renewable Sciences, Inc.Inventors: Linda A. Kunz, Steven A. Cohen
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Patent number: 10295497Abstract: A disposable screen-printed microchip based on an organic membrane sensitive layer is presented. The microchip is highly responsive for the determination of Lead(II). The microchip is composed of a composite sensitive material which comprises carbon nano-tubes “CNTs” and titanium (IV) oxide nano-particles embedded in a PVC membrane which was deposited on the surface of a plastic screen printed micro-electrode using a new methodology. The prepared disposable microchip provides a linear response for Pb2+ ions covering the concentration range of 1×10?6 to 1×10?1 mole L?1 with high sensitivity (49 mV), a long life span (>4 months) and short response time (10 s). The merits offered by the micro-sensor or microchip include small size, simple fabrication, mass production, integration feasibility and cost effectiveness and automation.Type: GrantFiled: June 28, 2016Date of Patent: May 21, 2019Assignee: King Abdulaziz City for Science and Technology (KACST)Inventors: Hassan Abdou Arida, Mohammad Ateeq AlDosari
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Patent number: 10292734Abstract: Systems and methods are described that may provide an efficient way to retrieve microneedles from tissue. For example, magnetic material may be incorporated into one or more microneedles. The microneedles may be delivered to a region of tissue via a backing material, such as a transdermal patch. The microneedles may provide therapeutic drug delivery and/or diagnostic information about the tissue or, more generally, the body containing the tissue. To retrieve the microneedles, a retrieval magnet may apply a magnetic field to the region of tissue where the microneedles were delivered. The magnetic field may attract the microneedles to aid in extraction of the microneedles from the tissue. In some embodiments, an excitation light source and light sensor may be included in the system and method to determine whether the microneedles were retrieved from the tissue.Type: GrantFiled: April 14, 2015Date of Patent: May 21, 2019Assignee: Verily Life Sciences LLCInventor: Timothy Ruckh
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Patent number: 10292892Abstract: A pneumatic lower extremity gait rehabilitation training system includes a support device for reducing the burden of supporting a user's body weight by lower extremity in a walking therapy, an exoskeleton rehabilitation device for adjusting the user's walking coordination at a treadmill, a center-of-gravity adjusting device for adjusting a change of upper and lower centers of gravity, and a remote monitoring device for receiving and capturing a signal of an angle displacement of a joint mechanism in a walking cycle. The user may support her/his body weight by the support device and the center-of-gravity adjusting device to reduce the gravity exerted onto the user's legs. The exoskeleton rehabilitation device improves the flexibility, safety and lightweight of walking and requires fewer driving elements. The remote monitoring device sends analyzed signals to the treadmill to adjust the user's walking speed, so as to improve the rehabilitation effect.Type: GrantFiled: September 12, 2016Date of Patent: May 21, 2019Assignee: Lunghwa University of Science and TechnologyInventors: Ching-Sheng Lee, I-Hsun Li, Hsin-Han Chiang, Lian-Wang Lee, Fu-Chen Hong, Rui-Peng Chen, Wei-Gan Chen
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Patent number: 10298319Abstract: It is an object to monitor signal flow (optically switched state) in an optical node without using a monitor light. In each of output ports of the optical node, a part of output signals is turned back, and the output signal light is subjected to intensity modulation or phase modulation, assigned port identification information, and allowed to reverse in the optical node. From an input port corresponding to the reversed output signal, a plurality of signals turned back are output. The plurality of signals are appropriately converted into intensity modulation from phase modulation and separated by a device having a spectroscopic function, and identification information is read out based on an intensity of a signal light for each signal, thereby determining an optically switched state to an output port corresponding to the input port.Type: GrantFiled: November 10, 2016Date of Patent: May 21, 2019Assignee: National Institute of Advanced Industrial Science and TechnologyInventors: Takayuki Kurosu, Kiyo Ishii, Satoshi Suda, Shu Namiki
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Patent number: 10292630Abstract: A flexible, body-mountable analyte sensing device includes a flexible substrate configured for mounting to skin of a living body. The sensing device additionally includes optical fiber attached to the flexible substrate and configured to penetrate the skin such that an analyte-sensitive substance disposed on the end of the optical fiber can detect an analyte in interstitial fluid. A color, fluorescence intensity, or other optical property of the analyte-sensitive substance is related to the concentration or other property of the analyte. Light reflected, scattered, fluorescently emitted, or otherwise emitted from the analyte-sensitive substance is transmitted via the optical fiber and detected by a light sensor on the flexible substrate. Such emitted light can be emitted in response to illumination of the analyte-sensitive substance via the optical fiber. The sensing device is configured to wirelessly indicate detected concentrations or other information about the analyte in the interstitial fluid.Type: GrantFiled: June 1, 2015Date of Patent: May 21, 2019Assignee: Verily Life Sciences LLCInventors: Jaclyn Leverett Wasson, William James Biederman, Zenghe Liu, Brian Otis
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Patent number: 10292810Abstract: Embodiments of an intraocular lens are described. The intraocular lens includes a lens having a center and having positive or negative optical power and a pinhole mask formed on the lens. The pinhole mask includes one or more annular sections whose centers substantially coincide with the center of the lens, each of the one or more concentric annular sections having variable opacity, and a central section that is permanently transparent, the radius of the central section being adapted to allow the central section to act as a pinhole when the one or more concentric annular sections are made opaque.Type: GrantFiled: February 26, 2016Date of Patent: May 21, 2019Assignee: Verily Life Sciences LLCInventors: Joshua N. Haddock, Dimitri T. Azar
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Patent number: 10295885Abstract: A wideband ultra-high refractive index mesoscopic crystal structure including: a first layer with high-conductivity unit bodies arranged in a matrix form, and a low-conductivity material disposed between the high-conductivity unit bodies; a second layer with high-conductivity unit bodies arranged in a matrix form, and a low-conductivity material disposed between the high-conductivity unit bodies; a first shield layer existing between the first and second layers and made of a low-conductivity material; and a second shield layer made of a low-conductivity material disposed on a side of the second layer such that the second layer is disposed between the first shield layer and the second shield layer, wherein the high-conductivity unit bodies in the first layer overlap the high-conductivity unit bodies arranged in the second layer, and wherein the first layer, the first shield layer, the second layer, and the second shield layer are sequentially stacked one or more times.Type: GrantFiled: March 21, 2018Date of Patent: May 21, 2019Assignee: Korea Advanced Institute of Science and TechnologyInventors: Jonghwa Shin, Yong-Hee Lee, Tae Yong Chang
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Patent number: D849144Type: GrantFiled: February 6, 2018Date of Patent: May 21, 2019Assignee: Shenzhen Tianyuwei Science and Technology Co., Ltd.Inventor: Hui Xiao
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Patent number: D849266Type: GrantFiled: February 22, 2016Date of Patent: May 21, 2019Assignee: Exact Sciences CorporationInventor: Timothy E. Higgins