Patents Assigned to Sciences
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Patent number: 12285007Abstract: An intelligent air-assisted spraying device for orchards includes a traction mechanism, a spaying system, a collecting system, and a processing-controlling system. The traction mechanism is provided with a spray tank. The spaying system includes a main body connected to the spray tank and multiple spraying tubes, first ends of the spraying tube are communicated with the main body, and second ends of the spraying tubes are capable of rotating. The collecting system is configured to collect a contour and a volume of the canopy, and branch and leaf density of a fruit tree. The processing-controlling system is configured to obtain multiple spraying areas, calculate an air outlet angle of each spraying tube, and control a rotation of the second end of each spraying tube according to the air outlet angle. The device can adjust the spraying direction of each spraying tube, and the quality of pesticide application can be improved.Type: GrantFiled: May 21, 2024Date of Patent: April 29, 2025Assignee: Intelligent Equipment Research Center, Beijing Academy of Agriculture and Forestry SciencesInventors: Liping Chen, Hanjie Dou, Changyuan Zhai, Fan Feng, Wei Zou, Si Li, Shuo Yang, Jian Song
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Patent number: 12287558Abstract: A nonlinear optical crystal of guanidinium tetrafluoroborate has a chemical formula of [C(NH2)3]BF4 and a molecular weight of 146.89, belongs to the trigonal crystal system, has a space group of R3m; has lattice parameters of a=7.4634(10)?, b=7.4634(10)?, c=9.1216(19) (6)?, and Z=3; has an ultraviolet cutoff edge of 200 nm; and has a frequency-multiplication response that is 4-5 times that of the commercialized nonlinear optical crystal KDP. A hydrothermal method, a room-temperature solution method, an evaporation method or a solvothermal method is used to grow the crystal in a centimeter-scaled size. The crystal can produce frequency-doubling, frequency-tripling, frequency-quadrupling, frequency-quintupling or frequency-sextupling harmonic light output from the fundamental frequency light of 1064 nm generated by a Nd:YAG laser, and/or can produce ultraviolet and deep-ultraviolet frequency-multiplication light output below 200 nm.Type: GrantFiled: December 22, 2021Date of Patent: April 29, 2025Assignee: XINJIANG TECHNICAL INSTITUTE OF PHYSICS & CHEMISTRY, CHINESE ACADEMY OF SCIENCESInventors: Shilie Pan, Miriding Mutailipu, Ming Xia, Jian Han
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Patent number: 12285421Abstract: The present invention relates to new uses of a 5-HT4 receptor agonist, specifically Isopropyl-3-{5-[1-(3-methoxypropyl)piperidin-4-yl]-[1,3,4]oxadiazol-2-yl}-1H-indazole (Compound-1) or a pharmaceutically acceptable salts thereof, for the treatment of dementia due to menopause, senile dementia, cognitive deficits associated with schizophrenia, depression, chemotherapy-induced cognitive impairment, and behavioral and psychological symptoms of dementia such as apathy/indifference, agitation, aggression, depression, anxiety, irritability/lability, dysphoria, aberrant motor behavior, delusions, hallucinations, elation/euphoria, psychosis, disinhibition, sleep and night time behavior disorders or appetite and eating disorders. The present invention further provides use of the 5-HT4 receptor agonist in the manufacture of medicament intended for the treatment of the disorders described herein.Type: GrantFiled: October 17, 2019Date of Patent: April 29, 2025Assignee: SUVEN LIFE SCIENCES LIMITEDInventors: Ramakrishna Nirogi, Abdul Rasheed Mohammed, Anil Karbhari Shinde, Venkata Ramalingayya Grandhi, Pradeep Jayarajan, Vijay Benade, Gopinadh Bhyrapuneni, Venkateswarlu Jasti
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Patent number: 12286468Abstract: The invention relates to a polypeptide, such as an Affimer polypeptide, comprising an amino acid sequence having at least 80% identity to amino acid residues 1 to 11, 13 to 15, 17 to 19, 21 to 25, 27 to 28, 35 to 37, 39, 41, 43 to 44, 46 to 47, 49 to 50, 52 to 53, 55 to 58, 63 to 64, 66, 68 to 82, 84 to 85, and 87 to 98 of SEQ ID NO: 1; characterized in that said polypeptide comprises one or mutations relative to SEQ ID NO: 1. The invention also relates to various methods and nucleic acids.Type: GrantFiled: February 8, 2024Date of Patent: April 29, 2025Assignee: Avacta Life Sciences LimitedInventors: Geoffrey William Platt, Graham Robert Pye-Smith Spence
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Patent number: 12285009Abstract: A system and method facilitates transfers of specimen containers (e.g., vials with caps) between storage cassettes and carrier cassettes. The storage cassettes are designed to be stored in cryogenic refrigerators while the carrier cassettes are designed to be temporarily stored in a portable carrier. A workstation includes a well and removable buckets positioned in the well. The buckets are sized to hold the storage cassettes and carrier cassettes. One or more arrays of antennas underlie the well to allow interrogation of wireless transponders carried by the specimen containers. Improved storage cassettes and carrier cassettes are also described.Type: GrantFiled: September 23, 2021Date of Patent: April 29, 2025Assignee: TMRW Life Sciences, Inc.Inventors: Brian Joseph Bixon, Cynthia Hudson, Alan Leroy Murray
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Patent number: 12286393Abstract: The invention provides a process for refining bio-based propylene glycol, wherein impurities having boiling points close to that of propylene glycol are separated. In this process, C5-C20 oleophilic alcohol compounds, C5-C20 alkanes and/or C4-C20 oleophilic ketone compounds are subjected to azeotropism as an azeotropic solvent together with the bio-based propylene glycol to obtain an azeotrope containing propylene glycol. Then the azeotropic solvent in the azeotrope is separated to obtain a crude propylene glycol which is further purified to obtain propylene glycol.Type: GrantFiled: January 17, 2023Date of Patent: April 29, 2025Assignee: Changchun Meihe Science and Technology Development Co., Ltd.Inventor: Yi Yuan
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Patent number: 12285469Abstract: Methods of making the M or L complex of the botulinum neurotoxin E with its associated neurotoxin binding protein(s) (NBP), and methods of using to treat pain and wrinkles by injecting locally. Methods of making and isolating the L and M complex comprise a multi-step process of: providing a bacterial cultured media comprising the complex of botulinum neurotoxin E and neurotoxin binding proteins; centrifuging and pelletizing the cultured media; stirring the pelletized culture at 0 to 10° C. over a period of 4 to 24 hours; centrifuging the stirred solution to obtain a supernatant; precipitating the supernatant and filtering to obtain the precipitate; and dissolving the precipitate, centrifuging and filtering to obtain a solution comprising M complex and/or L complex of botulinum neurotoxin E and its NBP; and passing the solution through a functionalized sephadex ion exchange column to isolate the complex.Type: GrantFiled: March 11, 2024Date of Patent: April 29, 2025Assignee: Institute of Advanced Sciences, Inc.Inventors: Bal Ram Singh, Raj Kumar
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Patent number: 12286616Abstract: Provided is an alga belonging to Cyanidiophyceae having a diploid cell and a haploid cell form. Also provided is a nutrient composition containing an alga belonging to Cyanidiophyceae or an extract thereof.Type: GrantFiled: November 28, 2018Date of Patent: April 29, 2025Assignee: JAPAN SCIENCE AND TECHNOLOGY AGENCYInventors: Shin-ya Miyagishima, Shunsuke Hirooka
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Patent number: 12288957Abstract: Embodiments of the microwave amplification system are described. In an embodiment, a microwave amplification system includes a microwave amplifier that contains a paramagnetic material with an impurity. The impurity has a plurality of nuclear spin and electron spin-based energy levels. The system includes an input to receive a pumping signal which is transmitted to the microwave amplifier to cause a population inversion in the impurity and excite it to one of the nuclear spin and electron spin-based energy levels. The system further includes another input to receive an input signal to be amplified by the microwave amplifier, the input signal having a lower power than the pumping signal. Once transmitted to the microwave amplifier, the input signal is amplified by the excited state of the impurity in the microwave amplifier thereby generating an amplified signal.Type: GrantFiled: June 12, 2023Date of Patent: April 29, 2025Assignee: Okinawa Institute of Science and Technology School CorporationInventors: Yuimaru Kubo, Jason Robert Ball, Petr Moroshkin, Denis Konstantinov
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Patent number: 12288477Abstract: A neck mechanism for a mannequin comprises three or more joint units serially connected to provide joints for three or more rotational degrees of freedom (DOF). A rotational axis of a first DOF is configured to be aligned with a lateral axis of the mannequin. A rotational axis of a second DOF is configured to be aligned with an anterior-posterior axis of the mannequin. A rotational axis of a third DOF is configured to be aligned with a cranial-caudal axis of the mannequin. A bottom one of the joint units is adapted to be connected to a torso of the mannequin, and a top one of the at least three joint units is adapted to be connected to a skull. The mannequin may also have a skull connected to the top one of the joint units, and a trunk connected to the bottom one of the joint units. A system for simulating cervical spine motions is also provided.Type: GrantFiled: May 19, 2023Date of Patent: April 29, 2025Assignee: SOCIETE DE COMMERCIALISATION DES PRODUITS DE LA RECHERCHE APPLIQUÉE SOCPRA SCIENCES ET GÉNIE S.E.C.Inventors: Patrick Boissy, Mathieu Hamel, François Cabana, Karina Lebel
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Patent number: 12285160Abstract: The present technology relates generally to devices and methods for closing percutaneous punctures, and more particularly to a multi-lumen tamper for such a device. A vascular closure device for sealing a percutaneous puncture in a wall of a body passageway is disclosed, the vascular closure device including a plug configured to engage a surface of the puncture; a suture configured coupled to the plug; a locking member configured to engage the plug; and a tamper comprising a first lumen and a second lumen.Type: GrantFiled: September 16, 2021Date of Patent: April 29, 2025Assignee: Teleflex Life Sciences LLCInventors: Greg Alan Walters, Samuel Nardone
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Patent number: 12287719Abstract: The present invention relates to an activity recognition system balanced between versatility and individuation, comprising a communication framework jointly formed by a data collecting terminal, a computing device, and a cloud computing platform, the activity recognition system uses the communication framework to conduct personnel activity recognition and model updating, and the edge computing device further comprises a model training module and an activity recognition module, and the model training module retrieves a local activity recognition model by continuously verifying user IDs, and uses the first data to train a versatile network structure and an individualized network structure of the local activity recognition model in a way that individuation features of the user and versatility features of the model are fused with each other, so that the personnel activity recognition process conducted by the activity recognition module.Type: GrantFiled: December 4, 2020Date of Patent: April 29, 2025Assignee: HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGYInventors: Jiang Xiao, Huichuwu Li, Minrui Wu, Hai Jin
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Patent number: 12287311Abstract: Disclosed is a synchronous and dynamic loading method in electro-magneto-thermo-mechanical multi-field coupling conditions. The method comprises the following steps: applying maximum pulse current to a test object by a pulse power supply to realize loading in extreme electric field and magnetic field conditions; meanwhile, generating a large amount of friction heat by the high-speed rotation of a rotating body and the friction of the test object to realize loading in an extreme-temperature field combined with a large amount of Joule heat and arc heat; synchronously applying pressure to the rotating body by a pressure device to realize loading of extreme force combined with the gravity of the rotating body and the friction force between the rotating body and the test object.Type: GrantFiled: November 21, 2022Date of Patent: April 29, 2025Assignee: Hefei Institutes of Physical Sciences, Chinese Academy of SciencesInventors: Liansheng Huang, Xiaojiao Chen, Shiying He, Xiuqing Zhang, Chuan Li
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Patent number: 12286348Abstract: An embodiment of the present invention provides a noble gas hydride having the following formula 1: NgnHm. In formula 1, Ng represents a noble gas atom, n represents an integer from 1-8, and m represents an integer from 1-46.Type: GrantFiled: July 6, 2020Date of Patent: April 29, 2025Assignee: TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventor: Kazuo Watanabe
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Patent number: 12287441Abstract: The present invention belongs to the technical field of geological exploration deep Earth. The system of the present invention is configured to: collect seismic data, and preprocess original seismic data to obtain standardized gamma ray logging parameters; extract features from the standardized gamma ray logging parameters to obtain a variance attribute curve while drilling; obtaining a formation thickness prediction model of each set based on the variance attribute curve while drilling; acquire frequency-division seismic data based on the standardized seismic data by means of a frequency-division processing method based on wavelet transform; acquire optimal seismic frequency band information based on a predicted formation thickness value of each set; establish a geological prediction model of the current formation based on the frequency-division seismic data, the optimal seismic frequency band information, historical gamma ray logging parameters and the standardized gamma ray logging parameters.Type: GrantFiled: January 14, 2024Date of Patent: April 29, 2025Assignee: Institute of Geology and Geophysics, Chinese Academy of SciencesInventors: Fei Tian, Qingyun Di, Wenhao Zheng, Yongyou Yang, Wenjing Cao
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Patent number: 12286581Abstract: The present disclosure relates to a colored radiative cooling device that includes a selective heat transfer layer between a spectral selective filter and a thermal emitter, and a method of cooling an object by using the colored radiative cooling device.Type: GrantFiled: December 23, 2021Date of Patent: April 29, 2025Assignee: Korea Advanced Institute of Science and TechnologyInventors: Jonghwa Shin, Suwan Jeon
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Patent number: 12286765Abstract: A single-hole ultrasonic detection device for continuous integrity and a rock entry depth of a concrete diaphragm wall and a method using the same are provided. the single-hole ultrasonic detection device includes an apparatus host, an ultrasonic transducer and an ultrasonic signal feedback device, and the apparatus host is respectively connected to the ultrasonic transducer and the ultrasonic signal feedback device via a corresponding one of signal lines, the apparatus host includes an ultrasonic transmitter and an ultrasonic signal collector, the ultrasonic transmitter is configured to generate ultrasonic waves and the ultrasonic waves are transmitted via the ultrasonic transducer, the ultrasonic transducer is configured to collect and recover a reflected wave of the ultrasonic waves, convert signals of the reflected wave of the ultrasonic waves into electric signals, and send the electric signals back into the apparatus host.Type: GrantFiled: January 9, 2023Date of Patent: April 29, 2025Assignee: Jiangxi Academy of Water Science and EngineeringInventors: Jianglin Gao, Da Liu, Songtao Hu, Yan Li, Fang Chen, Hongyou Guo, Liang Sun, Jianqing Zhang
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Patent number: 12286575Abstract: A phosphor having a favorable emission peak wavelength, narrow full width at half maximum, and/or high emission intensity is provided. Additionally, a light-emitting device, an illumination device, an image display device, and/or an indicator lamp for a vehicle having favorable color rendering, color reproducibility and/or favorable conversion efficiency are provided. The present invention relates to a phosphor including a crystal phase having a composition represented by a specific formula, and when, in a powder X-ray diffraction spectrum of the phosphor, the intensity of a peak that appears in a region where 2?=38-39° is designated as Ix and the intensity of a peak that appears in a region where 2?=37-38° is designated as Iy, the relative intensity Ix/Iy of Ix to Iy is 0.140 or less, and a light-emitting device comprising the phosphor.Type: GrantFiled: December 4, 2023Date of Patent: April 29, 2025Assignees: Mitsubishi Chemical Corporation, NATIONAL INSTITUTE FOR MATERIALS SCIENCEInventors: Tomoyuki Kurushima, Yuhei Inata, Naoto Hirosaki
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Patent number: 12285438Abstract: The present disclosure is broadly concerned with the field of cancer immunotherapy. For example, the present invention generally relates to an immune cell comprising a genetically engineered antigen receptor that specifically binds to a target antigen and a genetic disruption agent that reduces or is capable of reducing the expression in the immune cell of a gene that weakens the function of the immune cell.Type: GrantFiled: March 22, 2022Date of Patent: April 29, 2025Assignees: CUROCELL INC., KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Chan Hyuk Kim, Young-Ho Lee, Yujean Lee, HyeongJi Lee, Sang Hoon Lee
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Patent number: 12287229Abstract: An aspect of the present invention pertains to a method for determining the volumetric flow rate of a compressible fluid flow flowing through a volume flowmeter having a flow inlet, a wheel downstream of the flow inlet and a constriction downstream of the flow inlet and upstream of the wheel, the compressible fluid flowing through the flow inlet and actuating the wheel. The method comprises measuring the rotational speed of the wheel and determining the permanent pressure loss across the wheel based on the measured rotational speed. The method further comprises measuring the fluid pressure of the compressible fluid flow at the flow inlet and determining whether the compressible fluid flow in the volume flowmeter is in the subsonic or in the supersonic regime based on the determined permanent pressure loss and the measured fluid pressure.Type: GrantFiled: July 6, 2020Date of Patent: April 29, 2025Assignee: LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Jérôme Polesel, Mathieu Gerard