Abstract: The present invention relates to anti-metabotropic glutamate receptor subtype 2 (mGluR2) conformational single domain antibodies and uses thereof in particular in the therapeutic and diagnostic field.

Abstract: Heterojunction structure, also referred to as a heterostructure, of semiconductor material, in particular for a high electron mobility transistor (HEMT), includes a substrate, a stack of at least three buffer layers of a same semiconductor material with a wide bandgap EG1 based on a column-III nitride, namely an unintentionally doped first buffer layer, a second buffer layer, an unintentionally doped third buffer layer, an unintentionally doped intermediate layer, and a barrier layer arranged on the intermediate layer, said barrier layer being of a semiconductor material with a wide bandgap EG2 based on a column-III nitride; the second buffer layer has constant P+ doping throughout some or all of its thickness; and the third buffer layer includes a first region which is unintentionally doped throughout its entire thickness and at least one second region adjacent to said first region with N+ doping surrounding the first region.

Abstract: The present invention relates to a process for hydroxylation of a compound of formula (I) by reacting the compound of formula (I) with an oxidizing agent, in the presence of a titanium silicalite zeolite prepared by crystallization preceded by a maturing step. The present invention also relates to a titanium silicalite zeolite and to the process for preparing same.

Abstract: The invention concerns an aerosol charger having electrical discharge comprising: a body (2); an ion source (3) comprising two electrodes (31, 32); the charger being characterized in that the body (2) and at least a first electrode (32) of the ion source (3) are aligned along a same axis of longitudinal symmetry (AA?) of the charger, the body (2) surrounding the first electrode (32) in such a way as to define an area (5) for an aerosol to flow between a space defined between the body (2) and the first electrode (32); and in that the first electrode (32) comprises a hole (321) in communication with the area (5) for the aerosol (Ae) to flow, the hole (321) being designed to allow ions formed at the ion source (3) to pass therethrough in order for them to mix with an aerosol (Ae) flowing in the area (5) for the aerosol (Ae) to flow.

Abstract: An anode compartment for rechargeable lithium or sodium batteries, including: a solid electrolyte; a collector deposited on the solid electrolyte; and an active material made of lithium metal or sodium metal which has been grown between the solid electrolyte and the collector in order to form an electrode made of lithium metal or sodium metal with the collector, in which the collector is made of an amorphous alloy. A method for manufacturing such an anode compartment and a battery including said anode compartment is also presented.

Abstract: The present invention relates to anti-HER2 single domain antibodies, polypeptides comprising thereof and their use for treating cancer.

Abstract: The invention concerns a device for controlling the charge of an aerosol comprising: —an aerosol inlet area; —a discharge area having dielectric barriers, in which charged species are generated, the discharge area and the aerosol inlet area being arranged relative to one another in such a way that the aerosol introduced in this way does not flow via the discharge area; —a mixing area for mixing the aerosol with a portion of the charged species from the discharge area; —a post-discharge area linked to the discharge area, the aerosol inlet area and the mixing area being arranged in such a way that at least a portion of a stream flowing in the post-discharge area drives at least a portion of the charged species formed in the discharge area and expelled from the discharge area by electrostatic repulsion towards said mixing area.

Abstract: The present invention relates to an animal model of myasthenia gravis, and to uses thereof.

Abstract: A method for preparing a solid bitumen material at ambient temperature, the method comprising at least the steps of: a) preparing a stabilized emulsion of bitumen drops in a water phase that has a pH of 2 to 4; b) preparing a silica sol or silica gel from a first silicon oxide precursor that has a pH of 2 to 4; c) mineralizing the emulsion of bitumen drops from step a) with the silica sol or gel from step b); d) mineralizing the emulsion of bitumen drops from step c) having a maximum pH of 1 with a second silicon oxide precursor; e) separating the material from the water phase.

Abstract: The present invention relates to novel neurosteroids, especially derivatives of allopregnanolone and of epiallopregnanolone of formula (I) and the uses thereof as medicament for the treatment of neuropathologies, in particular neuropathies induced by the chemotherapy of a cancer. These molecules according to the invention have both preventative and curative effects. The neurosteroids according to the invention may also be of use in the treatment of neurodegenerative disorders, in particular for preventing neuronal cell death. They may thus be used as neuroprotectants and/or as an agent that stimulates neuronal proliferation.

Abstract: The invention relates to a method for recovering organic fibers from a composite material comprising a polymer matrix and organic fibers, wherein the method comprises the following steps: providing a solution comprising a mixture of water and alcohol; placing the composite material inside a reactor; contacting the mixture and the composite material in order to perform a solvolysis reaction of the composite material; and recovering the organic fibers; wherein the pressure and the temperature in the reactor are adjusted such as to fall within the homogeneous sub-critical range of the phase diagram, within the super-critical range or near the critical point; and wherein the temperature is lower than the melting temperature of the organic fibers.

Abstract: A method and device for electrodeposition in cylindrical geometry. A method for electrochemically depositing a thin layer on a flexible substrate, comprising: providing, in an electrolysis bath, a first closed cylinder in a second hollow cylinder, applying the flexible substrate to one of the surfaces chosen from the outer surface of the first cylinder and the inner surface of the second, the flexible substrate forming a first electrode, providing, in the electrolysis bath, a second electrode, and applying a potential difference between the first electrode and the second electrode in order to electrodeposit the thin layer on the flexible substrate.

Abstract: Disclosed is a method for reducing organic compounds using catalysts containing nickel (0) from metal hyperaccumulator plants. The method can be implemented in a green manner and is advantageous compared to methods using the known catalysts.

Abstract: The present invention relates to the field of medicine, in particular of research and diagnosis. It relates more particularly to a novel tool for detecting antibodies in a biological sample originating from a mammal. This tool, which is in the form of a protein chip, can be used in screening for new targets of interest involved in the occurrence of an autoimmune disease, in particular of a disease affecting the nervous system of a mammal, and also in the diagnosis or the monitoring of the progression of such an autoimmune disease. The invention also relates to a method for producing such a tool and also to kits comprising it and enabling its use.

Abstract: The present invention relates to a method for preparing commercial scale quantities of human functional Betacells and to the establishment of cell lines. It also relates to a method of diagnosis using Beta cell tumors or cells derived thereof. The method comprises sub-transplantation procedure to enrich the graft in proliferating Betacells, allowing to generate human Betacell lines. Such lines express little amount of insulin and have a gene expression profile that resembles to adult Betacells. In addition, the human Betacell lines are able to normalize glycemia of diabetic mice when transplanted, demonstrating their insulin secretion capabilities.

Abstract: Optical fiber (1) made of a photosensitive glass and with a rectangular cross section, wherein the radius of curvature of a corner of the rectangular cross section is smaller than 100 microns.

Abstract: The present disclosure relates to the use of a biopolymer as a sensitive material in a dielectric gas sensor for water vapor, carbon dioxide, and/or ethanol.

Abstract: A proton-conductive electrochemical device. The device comprising a positive electrode able to reduce an oxidizing species, a negative electrode able to oxidize a reducing species, and a proton-conductive electrolyte, in contact with the positive electrode and the negative electrode. In addition, the device further comprises a layer able to diffuse protons and electrons, said layer forming a protective barrier against contaminants for the proton-conductive electrolyte. The layer is in contact with the proton-conductive electrolyte on the one hand and the negative electrode on the other hand. A method for manufacturing such device is also provided.

Abstract: The invention relates to a surface treatment method for treating the inner walls of a microchannel made from a polymeric material that is at least partially photocured or thermoset. Said treatment is carried out via irradiation in the air at a wavelength of less than or equal to 300 nm. The invention also relates to a method for manufacturing a microfluidic device including such a surface treatment step.

Abstract: A system of control of interconnected signal emitters comprises controller modules, microcontrollers, electronic drivers and signal emitters. The connection input of each electronic driver is connected to the output of another electronic driver or to the output of a microcontroller, and the single output of each electronic driver is connected to the single connection input of another electronic driver or to the output of a microcontroller; each electronic driver being part of a driver chain between controller modules. Described developments comprise the use of Light-Emitting Diodes (LEDs), LED strips, sensors (e.g. ambient light, distance, motion, proximity, imaging, audio, temperature, pressure, etc), wired and/or wireless communication interfaces, power supply configurations and different topological arrangements (e.g. 2D, 3D, unidirectional or bidirectional arrangements, root or bridge vertices, interactive mesh, k-cyclic graphs, etc). Associated method steps (e.g.