Patents Assigned to SCIENTIFIQUE (CNRS)
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Patent number: 11512294Abstract: The disclosure pertains to the field of molecular means capable of binding to, and preferably of chelating, cGMP, appropriate for use in vitro or in vivo and preferably capable of targeting specific cellular compartments. The polypeptides of the disclosure comprise a chimeric construction derived from the N terminus part of PKG-I? and PKG-I?, and the two cGMP binding sites of the wild type PKG.Type: GrantFiled: November 2, 2018Date of Patent: November 29, 2022Assignees: SORBAOONE UNIVERSITE, CENTRE NATIONAL DE LA RECHARCHE SCIENTIFIQUE, INSTITUT NATIONAL DE LA SANTE ET LA RECHERCHE MEDICALE (INSERM)Inventors: Xavier Nicol, Oriol Ros Torres
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Patent number: 11510896Abstract: The present invention relates to a pharmaceutical or veterinary composition for its use in preventing and/or treating a MERS-CoV (Middle-East Respiratory Syndrome) coronavirus infection, characterised in that it comprises, in a suitable pharmaceutical vehicle, at least one compound chosen from apigenin and berberine.Type: GrantFiled: October 20, 2017Date of Patent: November 29, 2022Assignees: UNIVERSITE CLAUDE BERNARD LYON 1, INSTITUTE NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)Inventors: Manuel Rosa-Calatrava, Olivier Terrier, Anaïs Proust, Vincent Moules
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Patent number: 11512022Abstract: A nanoporous carbon-loaded cement composite that conducts electricity. The nanoporous carbon-loaded cement composite can be used in a variety of different fields of use, including, for example, a structural super-capacitor as an energy solution for autonomous housing and other buildings, a heated cement for pavement deicing or house basement insulation against capillary rise, a protection of concrete against freeze-thaw (FT) or alkali silica reaction (ASR) or other crystallization degradation processes, and as a conductive cable, wire or concrete trace.Type: GrantFiled: December 7, 2020Date of Patent: November 29, 2022Assignees: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE BORDEAUXInventors: Roland J. M. Pellenq, Aikaterini Ioannidou, Nicolas Chanut, Thibaut Divoux, Renal Backov, Franz-Josef Ulm
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Publication number: 20220370996Abstract: The present invention relates to a method for producing a support at least micrometric in size, photocatalytically active and at least in the visible range, containing nanocrystals each composed of from 80 to 100 mol % of TiO2 and from 0 to 20 mol % of at least one other metal or semi-metallic oxide, comprising the following steps, from an acidic aqueous reaction medium, at a heating temperature of between 20 and 60° C.Type: ApplicationFiled: June 30, 2020Publication date: November 24, 2022Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CY CERGY PARIS UNIVERSITÉ, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Nicolas PASTERNAK, Nancy LINDER
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Publication number: 20220370329Abstract: A method for the preparation of a gelled polysaccharide foam, which includes the following steps: (a) the preparation of a mixture including at least one solubilized polysaccharide chosen from alginates, pectic substances, carrageenans, and mixtures thereof, at least one solvent of the polysaccharide, at least one ionic crosslinking agent of the polysaccharide, the crosslinking agent being not available, optionally a plasticizer soluble into the solvent, optionally a surfactant, and optionally an additive, (b) foaming and gelling the mixture prepared at step (a) by incorporating a pH modifying gas, and (c) optionally drying the gelled foam obtained at step (b). Also, the gelled foam obtained from such a method as well as the uses thereof.Type: ApplicationFiled: October 27, 2020Publication date: November 24, 2022Applicants: URGO RECHERCHE INNOVATION ET DEVELOPPEMENT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS -Inventors: Sébastien ANDRIEUX, Wiebke DRENCKHAN-ANDREATTA
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Patent number: 11504049Abstract: A kit of two compositions comprising the same odorants in mixtures of different proportions is used for the measurement of olfactory discrimination capacity in subjects affected by a psychiatric disorder or disease involving mood disturbance, more particularly mood depression.Type: GrantFiled: January 21, 2020Date of Patent: November 22, 2022Assignees: INSTITUT PASTEUR, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)Inventors: Francoise Lazarini, Pierre-Marie Lledo, Eleni Siopi, Raphael Servignat D'Aout
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Patent number: 11509045Abstract: A body part for a motorized land vehicle is provided. The body part includes at least one wall made of a plastic material and including at least one housing forming a cavity for electromagnetic waves, said housing includes: at least one transceiver for transmitting and/or receiving an electromagnetic wave in said housing; at least one adaptable surface capable of reflecting the electromagnetic wave transmitted by the transceiver in a given direction (in a controlled manner) and, conversely, capable of reflecting the electromagnetic wave coming from the exterior of the housing toward the transceiver.Type: GrantFiled: August 23, 2019Date of Patent: November 22, 2022Assignees: ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, COMPAGNIE PLASTIC OMNIUM, GREENERWAVE SASInventors: Ronan Stephan, Mathieu Bancelin, Mathias Fink, Geoffroy Lerosey, Nicolas Etaix
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Patent number: 11504424Abstract: The present invention relates to an attenuated virus strain derived from a human metapneumovirus strain comprising the genome sequence represented by sequence SEQ ID NO. 1, said attenuated strain comprising one or more genetic modifications of said sequence SEQ ID NO. 1 attenuating the virulence of said strain.Type: GrantFiled: July 12, 2019Date of Patent: November 22, 2022Assignees: UNIVERSITE CLAUDE BERNARD LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ECOLE NORMALE SUPERIEURE DE LYON, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITE LAVALInventors: Manuel Rosa-Calatrava, Guy Boivin, Julia Dubois, Mario Andres Pizzorno, Olivier Terrier, Marie-Eve Hamelin, Marie-Helene Cavanagh
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Patent number: 11504094Abstract: An apparatus and a method for contrast-enhanced ultrasound (CEUS) including use of a fluid dynamics model for the analysis of dynamic contrast-enhanced ultrasound (DCEUS).Type: GrantFiled: July 27, 2018Date of Patent: November 22, 2022Assignees: (INSERM) INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE, UNIVERSITÉ DE TOURS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE BORDEAUX, INSTITUT POLYTECHNIQUE DE BORDEAUX (IPB)Inventors: Baudouin Denis de Senneville, Franck Perrotin, Jean-Michel Escoffre, Ayache Bouakaz
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Patent number: 11505508Abstract: A part includes a substrate having, adjacent to a surface of the substrate, at least a portion that is made of a material that contains silicon, and an environmental barrier formed on the surface of the substrate, the environmental barrier including a first layer including at least one first rare earth silicate and presenting grains with a mean size less than or equal to 1 ?m; and a second layer covering the first layer, the second layer including at least one rare earth silicate and presenting grains with a mean size greater than 1 ?m.Type: GrantFiled: December 29, 2017Date of Patent: November 22, 2022Assignees: SAFRAN CERAMICS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DE BORDEAUXInventors: Lisa Pin, Simon Arnal, Francis Rebillat, Fabrice Mauvy
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Publication number: 20220364981Abstract: The invention is a device and method for detecting an analyte in a medium. An exciting light source produces an exciting light wave, which propagates to the medium and heats the latter. The device comprises a transducer for detecting the heating of the medium. According to one embodiment, the transducer is a thermal transducer, configured to detect a variation in the temperature of the medium. According to another embodiment, the transducer is an acoustic transducer, configured to detect a photoacoustic wave propagating from the medium. Whatever the embodiment, the transducer employs a membrane, on which a waveguide is placed. The waveguide comprises a resonant optical cavity. Transduction is achieved by analyzing a variation in a resonant wavelength of the optical cavity.Type: ApplicationFiled: December 24, 2020Publication date: November 17, 2022Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE GRENOBLE ALPES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT POLYTECHNIQUE DE GRENOBLEInventors: Thomas LAUWERS, Skandar BASROUR, Jean-Guillaume COUTARD, Alain GLIERE, Guillaume LAFFONT
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Patent number: 11499002Abstract: A multi-epoxidized biphenyl compound has the formula (I) below wherein R, R1, R2 and R3 are as defined in the description, as well as mixtures of at least two of the compounds. These multi-epoxidized biphenyl compounds are fully suitable as main constituents of thermosetting epoxy resins, i.e. as polyepoxides precursors. They are beneficial substitutes for bisphenol A diglycidyl ether.Type: GrantFiled: November 7, 2018Date of Patent: November 15, 2022Assignees: ARIANEGROUP SAS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Etienne Savonnet, Brigitte Defoort, Henri Cramail, Stéphane Grelier, Etienne Grau
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Patent number: 11497384Abstract: An optical fibre having a functionalised distal exploration end including a sheath, and a ferrule rigidly connected to the sheath at the distal exploration end, characterised in that the distal exploration end has a functionalised head which is removably attached on the ferrule. Also, a method of assembling the optical fibre.Type: GrantFiled: May 15, 2018Date of Patent: November 15, 2022Assignees: KAMAX INNOVATIVE SYSTEM, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE LIMOGESInventors: Jérôme Desroches, Olivier Baudet, Martine Lejeune, Romain Trihan, Fabrice Lalloue
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Patent number: 11498877Abstract: A method of treating at least one silicon carbide fibre, the method including a) formation of a silica layer at the surface of a silicon carbide fibre having an oxygen content less than or equal to 1% in atomic percentage, the silica layer being formed by contacting this fibre with an oxidizing medium having a temperature greater than or equal to 50° C. and pressure greater than or equal to 1 MPa, and b) removal of the silica layer formed by hydrothermal treatment of the fibre obtained after implementation of step a) in which the fibre is treated with water at a pressure between saturating vapour pressure and 30 MPa and at a temperature less than or equal to 400° C.Type: GrantFiled: November 16, 2018Date of Patent: November 15, 2022Assignees: SAFRAN CERAMICS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Sylvie Loison, Lucile Henry, Cyril Aymonier, Chrystel Huguet
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Patent number: 11501110Abstract: The present invention relates to a method for learning class descriptors for the detection and the automatic location of objects in a video, each object belonging to a class of objects from among a set of classes, the method using: a learning base, composed from reference videos and containing annotated frames each comprising one or more labels identifying each object detected in the frames, descriptors associated with these labels and learned previously by a preprocessing neural network from the annotated frames of the learning base, an architecture of neural networks defined by parameters centralized on a plurality of parameter servers, and a plurality of computation entities working in parallel, a method in which, for each class of objects, one of the neural networks of the architecture is trained by using as input data the descriptors and the labels to define class descriptors, each computation entity using, for the computation of the class descriptors, a version of the parameters of the parameter serType: GrantFiled: June 8, 2018Date of Patent: November 15, 2022Assignees: INSTITUT MINES TELECOM, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventor: Jérémie Jakubowicz
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Patent number: 11499155Abstract: The present disclosure relates to an inhibitor of Dynamin 2 for use in the treatment of centronuclear myopathies. The present disclosure relates to pharmaceutical compositions containing Dynamin 2 inhibitor and to their use for the treatment of centronuclear myopathies. It also deals with a method for identifying or screening molecules useful in the treatment of a centronuclear myopathy.Type: GrantFiled: May 6, 2020Date of Patent: November 15, 2022Assignees: UNIVERSITE DE STRASBOURG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALEInventors: Jocelyn Laporte, Belinda Cowling, Hichem Tasfaout
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Patent number: 11499197Abstract: The invention relates to a method for in vitro predicting the outcome of an individual having a multiple myeloma, comprising the steps of: a. measuring the expression level of genes coding for kinases, b. calculating a score value for each genes; and c. classifying the individual as having a good or a bad outcome.Type: GrantFiled: October 30, 2018Date of Patent: November 15, 2022Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CENTRE HOSPITALIER UNIVERSITAIRE DE MONTPELLIER, UNIVERSITÉ DE MONTPELLIERInventors: Jerome Moreaux, Hugues De Boussac, Alboukadel Kassambara
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Patent number: 11498890Abstract: Process for the conversion of non-oxidative coupling of methane to ethylene, under non-oxidative conditions, comprising: providing a first stream containing at least 50 vol. % of methane based on the total volume of said first stream; providing a catalyst; putting in contact said first stream with said catalyst at a weight hour space velocity ranging from 0.5 to 100 h?1, a temperature ranging from 500° C. to 1100° C. and a pressure ranging from 0.1 MPa to 5 Mpa in the absence of oxygen; recovering a second stream containing unconverted methane if any, ethylene and hydrocarbons having at least 2 carbon atoms. Said process is remarkable in that said catalyst is a synthetic zeolite material, containing at least one metal M with silicon to metal M molar ratio Si/M as determined by inductively coupled plasma optical emission spectrometry ranging from 100 to 65440 and in that said metal M is incorporated inside of the zeolite tetrahedral sites.Type: GrantFiled: October 26, 2020Date of Patent: November 15, 2022Assignees: TOTALENERGIES ONETECH, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)Inventors: Florent Dubray, Svetlana Mintova, Jean-Pierre Gilson, Stanislav Konnov, Stijn Van Daele, Nikolai Nesterenko
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Patent number: 11497779Abstract: The present invention concerns novel Lactobacillus plantarum strains capable of promoting the growth of a subject, and more particularly the juvenile or prenatal growth of farm animals, and their uses as probiotics.Type: GrantFiled: August 17, 2018Date of Patent: November 15, 2022Assignees: ECOLE NORMALE SUPERIEURE DE LYON, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE CLAUDE BERNARD LYON 1Inventors: François Leulier, Maria Elena Martino
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Patent number: 11499929Abstract: An infrared-detecting device, includes an infrared detector configured to emit a signal representative of the thermal radiation of a hotspot, and a light source configured to emit an incident beam, preferably in a window of UV or visible wavelength. The infrared-detecting device furthermore comprises a synchronizing device connected to the light source and to the infrared detector or to the processing module, and configured to emit a synchronization signal, the infrared detector being configured to be activated in a preset time window depending on said synchronization signal.Type: GrantFiled: December 21, 2017Date of Patent: November 15, 2022Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Yannick De Wilde, Elodie Perros, Valentina Krachmalnicoff, Rémi Carminati, Albert-Claude Boccara