Patents Assigned to SCIENTIFIQUE (CNRS)
  • Publication number: 20220317028
    Abstract: A method for analysing a sample uses a resonant support having a surface on which a plurality of separated photonic crystals extends. At least two crystals are configured to capture the same analyte. A resonance wavelength associated with each crystal varies with an amount of analyte in contact with the crystal. The wavelengths define a resonance spectral band between 200-1500 nm. The transmission/reflection of the light is maximum at an associated resonance wavelength. The method includes: illuminating the support in the resonance spectral band, the intensity of the lamination being variable in band; acquiring a measurement image using an image sensor, the image having different regions-of-interest each optically coupled to a photonic crystal; using a reference image representative of an image acquired by the image sensor, when the support is illuminated in the resonance spectral band in a reference configuration; and comparing the measurement image with the reference image.
    Type: Application
    Filed: June 4, 2020
    Publication date: October 6, 2022
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CPE LYON FORMATION CONTINUE ET RECHERCHE, ECOLE CENTRALE DE LYON, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON, UNIVERSITE CLAUDE BERNARD LYON 1, AVALUN, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
    Inventors: Mathieu DUPOY, Taha BENYATTOU, Lotfi BERGUIGA, Jean-Marc FEDELI, Maryse FOURNIER, Nicolas GAIGNEBET, Cecile JAMOIS, Patrick POUTEAU
  • Publication number: 20220315539
    Abstract: A compound of formula (I), wherein R1, R2, R3 and R4 are selected from a saturated or unsaturated, branched or unbranched, cyclic or non-cyclic alkyl, or an amide, or a functional group, or a salt or a solvate thereof, or a protonated form thereof, and to the use thereof for the treatment of cancer.
    Type: Application
    Filed: September 2, 2020
    Publication date: October 6, 2022
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE D'AIX-MARSEILLE
    Inventors: Olivier SIRI, Zhongrui CHEN
  • Publication number: 20220314185
    Abstract: Method for manufacturing microcapsules enclosing a substance referred to as the active substance, in which method: there are provided an aqueous solution of a surfactant, an oily phase comprising the active substance and at least a first monomer X, and a polar phase having at least a second monomer Y; an O/W emulsion is prepared by adding the oily phase to the aqueous solution of the surfactant; the polar phase is added to the O/W emulsion in order to obtain a polymer by polymerisation of the X and Y monomers; starting from this reaction mixture, the microcapsules are isolated and comprise a wall which is formed by the polymer and which encloses the active substance; the polymer is a poly(beta-amino ester).
    Type: Application
    Filed: May 14, 2020
    Publication date: October 6, 2022
    Applicants: GEM INNOV, UNIVERSITÉ D'AIX MARSEILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Yves ORTAIS, Thierry RIBEIRO, Kaouthar OUDOUA, The Hien HO, Didier GIGMES, Catherine GUILLANEUF, Yohann GUILLANEUF
  • Publication number: 20220314686
    Abstract: Solvent transfer printing method for applying a pattern (1) made of a non-soluble material and non-dispersible (10) on the surface of an object (2), the method comprising the following steps: m1/forming a pattern (1) on a surface of a solvent-soluble substrate (3), m2/depositing the solvent-soluble substrate (3) on the surface of a solvent bath (5), on the side of the substrate opposed to the side on which the pattern is applied, in order to dissolve partially the substrate (3), m3/dipping the object (2) in the bath (5), so that the surface of the object (2) comes into contact with the pattern (1), m4/getting the object (2), on which the pattern (1) is applied, out of the bath (5), m5/drying the object (2).
    Type: Application
    Filed: May 23, 2022
    Publication date: October 6, 2022
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS -, UNIVERSITE DE RENNES 1
    Inventors: Maxime HARNOIS, Jacques EMMANUEL, Brice LE BORGNE
  • Publication number: 20220317031
    Abstract: A method for analysing a sample uses a resonant support. The sample extends on the support having a surface on which a plurality of separated photonic crystals extend. The sample extends between a light source and the crystals, wherein a resonance wavelength is associated with each crystal addressing the analyte and the wavelengths of the crystals define a resonance spectral band extending between 2 ?m and 20 ?m. The transmission or reflection of light by each crystal addressing the analyte is maximum at the associated resonance wavelength. The method includes illuminating the support by the light source, the light source emitting an illumination lightwave defining an illumination spectral band which at least partially covers the resonance spectral band, such that a plurality of crystals are simultaneously illuminated; acquiring an image of the support, and then determining the presence of the analyte in the sample from the image.
    Type: Application
    Filed: June 4, 2020
    Publication date: October 6, 2022
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CPE LYON FORMATION CONTINUE ET RECHERCHE, ECOLE CENTRALE DE LYON, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON, UNIVERSITE CLAUDE BERNARD LYON 1, COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES
    Inventors: Mathieu DUPOY, Maryse FOURNIER, Taha BENYATTOU, Cécile JAMOIS, Lotfi BERGUIGA, Nicolas GAIGNEBET, Thomas GEHIN
  • Publication number: 20220315535
    Abstract: In vitro or ex vivo methods for screening a quinoline derivative, or anyone of its pharmaceutically acceptable salt, presumed effective in treating and/or preventing an inflammatory disease, the method including: providing an eukaryotic cell, bringing into contact said cell with a quinoline derivative, measuring an expression of miR-124 in the cell, and selecting the candidate presumed effective in treating and/or preventing an inflammatory disease when the level of expression of miR-124 measured is increased relatively to a reference value.
    Type: Application
    Filed: May 17, 2022
    Publication date: October 6, 2022
    Applicants: ABIVAX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT CURIE, UNIVERSITE DE MONTPELLIER
    Inventors: Didier SCHERRER, Jamal TAZI
  • Patent number: 11457806
    Abstract: According to a first aspect, the present disclosure relates to a digital holography device (100) for full-field blood flow imaging of ocular vessels of a field of view of a layer (11) of the eye (10). The device comprises an optical source (101) configured for the generation of an illuminating beam (Eobj) and a reference beam (ELO), and a detector (135) configured to acquire a plurality of interferograms (I(x,y,t)) wherein an interferogram is defined as the signal resulting from the interference between the said reference beam (ELO) and a part of said illuminating beam (Eobj) that is backscattered from said layer (11).
    Type: Grant
    Filed: December 30, 2019
    Date of Patent: October 4, 2022
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS
    Inventors: Léo Puyo, Michael Atlan
  • Patent number: 11463020
    Abstract: A movement amplifying actuation device may include two piezoelectric beams, one beam being attached at a fixed point, and a hinge connecting a first beam and a second beam between them. Each hinge may include a first flexible portion connected to the first beam, a second flexible portion connected to the second beam, a first rigid portion connecting the first and second flexible portions, a second rigid portion capable of being positioned against a fixed point, and a third flexible portion connecting the second beam to the second rigid portion at a pivot point of the second beam such that the assembly formed by the second rigid portion and the second beam forms a lever around the pivot point. The flexible and rigid portions may form a single piece.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: October 4, 2022
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DE FRANCHE-COMTE, ECOLE NATIONALE SUPERIEURE DE MECANIQUE ET DES MICROTECHNIQUES
    Inventors: Sergio Lescano, Nicolas Andreff, Micky Rakotondrabe, Kanty Rabenorosoa, Brahim Tamadazte, Clément Bouderlique
  • Patent number: 11459460
    Abstract: Bitumen that is solid at ambient temperature in the form of granules that include a core made of a first bituminous material and a coating made of a second bituminous material, the second bituminous material having a total content of asphaltenes, extracted using n-alkane, of 30% to 50% by weight in relation to the total weight of the bitumen in the coating.
    Type: Grant
    Filed: May 22, 2017
    Date of Patent: October 4, 2022
    Assignees: TOTAL MARKETING SERVICE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Mouhamad Mouazen, Manuel Merce, Véronique Schmitt, Rénal Backov
  • Publication number: 20220305464
    Abstract: A process for preparing a catalyst material, includes the steps of: (a) providing a support material having surface hydroxyl (OH) groups, wherein the support material is ceria (CeO2), zirconia (ZrO2) or a combination of thereof; (b) reacting the support material having surface hydroxyl (OH) groups of step (a) with a precursor containing two transition metal atoms, each chosen independently from the group consisting of: W, Mo, Cr, Ta, Nb, V, Mn; (c) calcining the product obtained in step (b) in order to provide a catalyst material showing dual site surface species containing pairs of transition metal atoms derived from the precursor that are present in oxide form on the support material. Additionally, a catalyst material is obtained by the process set out above, and the catalyst material is used as an ammonia selective catalytic reduction (NH3-SCR) catalyst for nitrogen oxides (NOx) reduction.
    Type: Application
    Filed: June 4, 2019
    Publication date: September 29, 2022
    Applicants: TOYOTA MOTOR EUROPE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLAUDE BERNARD LYON 1, ECOLE SUPERIEURE DE CHIMIE PHYSIQUE ELECTRONIQUE DE LYON
    Inventors: Phuc Hai NGUYEN, Marc-Olivier CHARLIN, Cherif LARABI, Kai Chung SZETO, Mostafa TAOUFIK
  • Publication number: 20220305480
    Abstract: A process for preparing a catalyst material, includes: (a) providing a support material having surface hydroxyl (OH) groups, the support material is ceria (CeO2), zirconia (ZrO2) or a combination, and the support material contains between 0.3 and 2.0 mmol OH groups/g of the support material; (b) reacting the support material with at least one of: (b1) a compound containing at least one alkoxy or phenoxy group bound though its oxygen atom to a metal element from Group 5 (V, Nb, Ta) or Group 6 (Cr, Mo, W); (b2) a compound containing at least one hydrocarbon group bound though a carbon atom to a metal element from Group 5 or 6; (b3) a compound containing at least one hydrocarbon group bound though a carbon atom to a metal element which is copper (Cu); and (c) calcining the product obtained in step (b).
    Type: Application
    Filed: June 4, 2019
    Publication date: September 29, 2022
    Applicants: TOYOTA MOTOR EUROPE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLAUDE BERNARD LYON 1, ECOLE SUPERIEURE DE CHIMIE PHYSIQUE ELECTRONIQUE DE LYON
    Inventors: Phuc Hai NGUYEN, Nicolas MERLE, Marc-Olivier CHARLIN, Kai Chung SZETO, Mostafa TAOUFIK
  • Patent number: 11453886
    Abstract: The present invention relates to GFLV virus-like particles and the uses thereof in various fields, such as the pharmaceutical, agro, or veterinary areas.
    Type: Grant
    Filed: March 13, 2018
    Date of Patent: September 27, 2022
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE STRASBOURG, INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE, INSTITUT FRANCAIS DE LA VIGNE ET DU VIN, VRIJE UNIVERSTEIT BRUSSEL
    Inventors: Serge Muyldermans, Gérard Demangeat, Ahmed Ghannam, Léa Ackerer, Caroline Hemmer, Christophe Ritzenthaler, Vianney Poignavent
  • Patent number: 11452637
    Abstract: The present invention relates to an apparatus for cutting-out including a device for treating a L.A.S.E.R. beam generated by a femtosecond laser (1), and positioned downstream from said femtosecond laser, the treatment device comprising: a shaping system (3) positioned on the trajectory of said beam, for modulating the phase of the wave front of the L.A.S.E.R. beam according to a modulation set value calculated for distributing the energy of the L.A.S.E.R. beam in at least two impact points forming a pattern in its focal plane, an optical focusing system (5) downstream from the shaping system, the optical focusing system comprising a concentrator module for focusing the phase-modulated L.A.S.E.R.
    Type: Grant
    Filed: April 6, 2017
    Date of Patent: September 27, 2022
    Assignees: KERANOVA, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE JEAN MONNET SAINT ETIENNE
    Inventors: Fabrizio Romano, Aurelien Bernard, Cyril Mauclair, Emmanuel Baubeau
  • Publication number: 20220298024
    Abstract: A composition of general formula (1): Nax[MnaNibCrc]O2+y (1), wherein: 0.6?x?0.8; ?0.1?y?0.1; 0.55?a?0.7; 0.25?b?0.3; c?0.05; and a+b+c?1.0, an intermediate product for preparing a composition of general formula (1) and a process of synthesis, wherein the mixed sodium-transition metal oxide of general formula (1) may generally show an essentially or solely P2 structure, and may be used as a positive electrode material for a sodium ion secondary battery.
    Type: Application
    Filed: August 27, 2019
    Publication date: September 22, 2022
    Applicants: TOYOTA MOTOR EUROPE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Laurent CASTRO, Jun YOSHIDA, Claude DELMAS, Marie GUIGNARD, Elodie GUERIN
  • Patent number: 11445671
    Abstract: The present invention concerns an isolated polynucleotide responsible of haploid induction in maize plants and related processes. Additionally, the invention relates to plants that have been genetically transformed with the polynucleotide of the invention. The invention also relates to a process for screening a mutant plant population for enhanced haploid induction by using said isolated polynucleotide. The invention further relates to molecular markers associated with haploid induction in maize plants and their use in quality control for inducer lines.
    Type: Grant
    Filed: May 6, 2016
    Date of Patent: September 20, 2022
    Assignees: INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA), LIMAGRAIN EUROPE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Jean-Pierre Martinant, Jordi Comadran, Jean-Baptiste Laffaire, Peter Rogowsky, Thomas Widiez
  • Patent number: 11446626
    Abstract: The present invention relates to a method for the preparation of a colloidal aqueous suspension of stable zeolite nanocrystals having framework structures comprising at least one cation selected from Gd, Fe, Cu and Ce, said structures being loaded with a gas selected from O2, CO2 and mixtures thereof, to the colloidal aqueous suspension of zeolite nanocrystals obtained by such a process, and to the use of said suspension in therapy, more particularly in cancer therapy and hypoxia-related diseases and/or in diagnosis.
    Type: Grant
    Filed: August 7, 2018
    Date of Patent: September 20, 2022
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE CAEN NORMANDIE
    Inventors: Samuel Valable, Svetlana Mintova Lazarova, Clément Anfray, Valentin Valtchev, Omar Touzani, Myriam Bernaudin
  • Patent number: 11451722
    Abstract: The invention relates to a method for acquiring an image by an imager (20) comprising a matrix of pixels configured to generate an electric response when exposed to an incident light flux travelling through an optical path (21) in which is arranged a wavefront correction element (22), comprising the following steps: 1) initiating the exposure of the pixels to the incident light flux; 2) for a plurality of iterations during the exposure: 2.1) non-destructive reading of the electric responses of pixels of a region of interest; 2.2) determining an evolution of the spatial distribution of pixels in logarithmic mode previous iteration with respect to the previous iteration; 2.3) based on said evolution, establishing a command for the wavefront correction element (22) in order to correct the wavefront; 2.4) configuring the wavefront correction element, 3) reading the electric responses of the pixels resulting in an image.
    Type: Grant
    Filed: September 17, 2019
    Date of Patent: September 20, 2022
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SORBONNE UNIVERSITE, ECOLE NORMALE SUPERIEURE, UNIVERSITE DE PARIS, UNIVERSITE DE BOURGOGNE, OBSERVATOIRE DE PARIS
    Inventors: David Darson, Julien Dubois, Francois Colas
  • Patent number: 11446649
    Abstract: Disclosed is a nanocatalyst-type nanoscale composition including a nanoparticle semiconductor, plasmonic metal nanoparticles and an organic photosensitiser of the carbo-mer type. Also disclosed is a method for producing such a nano-catalyst. Also disclosed is use of the nanocatalyst for photoelectrolysis, in particular, for the photoelectrolysis of water, as well as to a power source including the nanocatalyst.
    Type: Grant
    Filed: October 16, 2017
    Date of Patent: September 20, 2022
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE RENNES 1, UNIVERSITÉ PAUL SABATIER TOULOUSE III
    Inventors: Jérémy Cure, Myrtil Kahn, Kévin Cocq, Gérald Casterou, Rémi Chauvin, Valérie Maraval, Hala Assi
  • Publication number: 20220289962
    Abstract: The present invention relates to electrically conductive nanocomposite particles comprising: a core consisting of a poly-C1-C6-alkyl-acrylate homopolymer or of a C1-C6 alkyl acrylate copolymer and an ?,?-unsaturated amide comonomer, a shell comprising a conductive polymer and a nonionic surfactant. The invention also relates to a process for the preparation of such particles, as well as their use for producing a print on a stretchable support.
    Type: Application
    Filed: September 2, 2020
    Publication date: September 15, 2022
    Applicants: UNIVERSITÉ DE PAU ET DES PAYS DE L'ADOUR, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Stéphanie REYNAUD, Pierre MARCASUZAA
  • Patent number: D965175
    Type: Grant
    Filed: February 24, 2021
    Date of Patent: September 27, 2022
    Assignees: UNIVERSITE DE VERSAILLES—SAINT QUENTIN EN YVELINES, CENTRE HOSPITALIER INTERCOMMUNAL DE POISSY-SAINT-GERMAIN, CENTRE HOSPITALIER UNIVERSITAIRE DE BORDEAUX, UNIVERSITE DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: François Vialard, Clément Jimenez, Christophe Geindre, Bruno Hiberty, Hugo Ducros