Abstract: The device for electrochemically synthesizing intermediate species of a chemical entity which comprises an electrochemical oxidation cell including a first working electrode and a first counter electrode, capable, when these first electrodes are subject to an electric potential, of generating the intermediate species by oxidation of a solution introduced into the electrochemical oxidation cell and comprising the chemical entity, and an electrochemical stabilization cell including a second working electrode and a second counter electrode respectively distinct from the first working electrode and counter electrode, capable, when these second electrodes are subject to an electric potential, of achieving reduction of a solution. The stabilization cell is connected in series to the oxidation cell so as to allow continuous reduction of the intermediate species generated in the oxidation cell. Applications can be in the pharmaceutical, agri-food and environment fields.

Abstract: A device is provided for controlling a piezoelectric actuator able to combine two types of piezoelectric actuator control, namely voltage control and charge control. Switching between charge control and voltage control takes place automatically, without added switching elements, according to the nature of the voltage applied to the input of the setup.

Abstract: The invention concerns a device forming a robotic finger comprising a base (100) forming a palm, at least one knuckle (500, 700, 900) articulated on the base (100) about two separate joints (200, 400) non-parallel to each other, at least two actuators (110, 120, 130, 140) and cable-linking means (112, 122) respectively linking the two actuators (110, 120) to drive elements of said two joints (200, 400), characterized in that the device comprises guide means (150, 151, 152) designed to guide the cables involved in the control of each joint (400, 600, 800) located after the first joint (200) on the base (100), in a common plane passing through the axis (202) of said first joint (200).

Abstract: The present invention relates to the use of a homeoprotein or a recombinant vector encoding said protein for treating or preventing DNA damage and/or cellular aging. In particular, the invention concerns the use of Engrailed for the treatment of Parkinson disease.

Abstract: A magnetic memory element includes a contact with a magnetic layer portion between a conductive layer portion and a non-magnetic layer portion. The magnetic layer has a magnetization perpendicular to the plane of the layers, and an angled conductive track-having a central portion extended by two arms, the contact being entirely arranged on the track. For each arm, a current flowing towards the contact along the median axis of the arm encounters the portion of the contact nearest to the arm primarily on the left thereof for one of the arms, and primarily on the right thereof for the other arm.

Abstract: Polymer network composition having a semi-crystalline covalently crosslinked polymer network including exchangeable covalent bonds and crosslinking bonds and at least an exchange reaction catalyst, wherein the number of crosslinking bonds is sufficient for the polymer network to be beyond the gel point and the number of exchangeable bonds is sufficient for the network to relax stresses and/or flow when conditioned at an appropriate temperature. Such compositions are characterized by the fact that the network is able to reorganize by exchange reactions that allow it to relax stresses and/or flow while maintaining network connectivity.

Abstract: The present invention relates to the fields of medicine and cancer treatment. The invention more specifically relates to the use of a panicein or a derivative thereof, to decrease or inhibit, in vitro or ex vivo, the Patched receptor drug efflux activity, in particular the chemotherapeutic drug efflux activity and chemotherapy resistance. The present disclosure further relates to uses of such compounds, in particular to prepare a pharmaceutical composition to allow or improve the efficiency of a therapy of cancer in a subject in need thereof. The compound of the invention can indeed be advantageously used, in combination with at least one chemotherapeutic drug, for treating cancer, for preventing cancer metastasis and/or for preventing cancer recurrence in a subject.

Abstract: The present invention relates to the use of interleukin-2 (IL-2) for treating a food allergy, either by inducing non-specific tolerance against food allergens, or in a desensitization protocol in combination with a food allergen.

Abstract: A material, especially a glassy material of pyrophosphate type, corresponding to the general formula (I): {[(M2+)1?x(R+)2x]2[(P2O74?)1?y(PO43?)4y/3]} n(H2O) in which x and y are positive rational numbers each between 0 and 0.8, and n is such that the weight percentage of water in the material is greater than 0 and less than or equal to 95. M2+ represents a bivalent ion of a metal chosen from calcium, magnesium, strontium, copper, zinc, cobalt, manganese and nickel, or any mixture of such bivalent ions. R+ represents a monovalent ion of a metal selected from potassium, lithium, sodium, and silver, or any mixture of such monovalent ions. This material in particular can be used in manufacturing of bone replacements or prosthesis coatings.

Abstract: The present disclosure relates to 2,6-diaminopurine (DAP) for use in the treatment of a disease caused by a nonsense mutation in a gene, leading to the premature insertion of a UGA stop codon.

Abstract: A prosthetic implant includes a cavity that opens at an outer face of the prosthetic implant, the cavity forming a housing for receiving: a printed circuit including a radio tag; and a cover which closes the cavity at least partially when positioned on the implant in a so-called closed position, the radio tag and printed circuit being removably housed in the cavity.

Abstract: A method for controlling an insulin injection device and a system for delivering insulin in a patient in need thereof. The method includes the steps of defining a time interval; receiving the level of blood glucose; computing an insulin dose to be injected in the next time interval, and transmitting the computed insulin dose to be injected to the insulin injection device.

Abstract: A process for obtaining borazane (NH3—BH3) includes introducing anhydrous liquid ammonia (NH3(l)) into a reactor thermostatically regulated to between a temperature ?1 and 40° C.; introducing, with stirring, into the reactor an amine borane complex (Am.BH3), the corresponding amine (Am) of which is soluble in anhydrous liquid ammonia only to a proportion of less than 10 g in 100 g of ammonia at 20° C., being introduced in an amount such that the mole ratio R=(NH3(l))/(Am.BH3) is greater than or equal to 5; stirring the mixture; stopping the stirring to obtain two demixed phases: a light phase constituted essentially of a solution of anhydrous liquid ammonia (NH3(l)) containing borazane; and a heavy phase constituted essentially of the amine corresponding to the amine borane complex introduced; isolating the borazane and drying under vacuum thereof; the temperature ?1 being greater than or equal to the melting point of the amine borane complex.

Abstract: A passive resonant optical gyroscope comprising a cavity and operating with three frequencies comprises: a first injecting laser to inject a first optical beam into the cavity in a first direction; a second injecting laser to inject a second optical beam into the cavity in an opposite direction; a third injecting laser to inject a third optical beam into the cavity in one of the aforementioned directions, one laser amongst the injecting lasers having a master frequency, the two other injecting lasers, called the first and second slave lasers, respectively having a first slave frequency and a second slave frequency; a master servocontrol device; a first servocontrol stage comprising first and second slave devices; and a second servocontrol stage comprising first and second optical phase-locking devices respectively comprising a first and second slave oscillator to generate a first radiofrequency offset signal and a second radiofrequency offset signal.

Abstract: The present invention relates to the use of haloapatites as catalysts of the dehydration reaction of ?-hydroxylated carboxylic acids or acid esters, in particular of lactic acid or of methyl lactate, and also to a process for producing unsaturated carboxylic acids or acid esters, in particular acrylic acid or methyl acrylate, in the gas phase in a stainless steel reactor, in the presence of such a catalyst.

Abstract: This invention relates to the direct grafting of a calixarene mostly onto the surface of a material, as well as to a grafting process, and certain calixarene intermediates useful for carrying the grafting process.

Abstract: The present invention relates to a cooling mixture comprising a fluorinated compound and a non-fluorinated compound, wherein the fluorinated compound is a hydrofluoroether and the non-fluorinated compound includes a carbonyl function, which has a flash point no lower than 23° C. and which is characterised by having low relative volatility. The present invention likewise relates to the use of such a mixture as a coolant in a heat-exchange device.

Abstract: The present invention relates to an optimized in vivo delivery system with endosomolytic agents for nucleic acid of therapeutic interest conjugated to molecules facilitating endocytosis, in particular for use in the treatment of cancer.

Abstract: A method for producing a propulsion nozzle, wherein the nozzle is produced from an ablative resin, the method including a step of pre-polymerization wherein an innovative aldehyde compound is used.

Abstract: The invention relates to a supercapacitor comprising: an electrolyte having a first end and a second end opposite the first end, a first electrode in contact with the first end of the electrolyte, and a second electrode in contact with the second end of the electrolyte. In particular, the electrolyte is made of a solid material that is ion-conductive and electronically insulating.