Abstract: Device for measuring the endogenous deformations of a structure of materials, during the transition of said structure from a liquid phase to a solid phase, comprising: a uniaxial test body suitable for being embedded in the structure; a deformation measurement fiber attached to the interior of the test body; a system connected to the measurement fiber and suitable for detecting signals representative of the deformations of the measurement fiber and for determining the endogenous deformations from these signals and from known mechanical properties of the materials of the test body, the test body having a rigidity comprised between 2 and 5 gigapascals.

Abstract: A process for selective partial hydrogenation of conjugated diene compounds includes at least one, preferably terminal, diene function and at least one additional carbon-carbon double bond, the process including reacting the conjugated diene compounds with hydrogen in the presence of an iridium-NHC based catalyst. The disclosure also relates to a reaction mixture that can be obtained at the end of the process. The disclosure also relates to the use of the reaction mixture.

Abstract: The present invention relates to the field of cancer and inflammatory diseases. More particularly, it aims to provide, for these purposes, novel conjugated forms of active ingredients belonging to the dolastatin family and having the formula as follows: It is also directed towards prodrug forms of these conjugates.

Abstract: The invention relates to a load-balancing device for an articulated arm capable of receiving a load having a weight, the balancing device being characterized in that it comprising a support system able to be fastened to a stationary element of the articulated arm, and an actuator element capable of being attached to a movable input element of the articulated arm, the balancing device also including a lever arm able to exert a force on the actuator element in order to apply said force on the input element of the articulated arm, the lever arm having an adjustable length as a function of the weight of the load.

Abstract: A device for quantifying a useful thermal energy available in a tank for storing a heated or cooled fluid or solid includes: a plurality of thermoelectric converters configured to be distributed in plural locations of the storage tank; an electric circuit interconnecting the thermoelectric converters; a device measuring a single electrical variable of the electric circuit; and a converter converting a single measurement of the single electrical variable into a value for quantification of the useful thermal energy available in the storage tank.

Abstract: A method for producing a contrast-amplifying support comprising an absorbing substrate carrying at least one absorbing layer comprises a design step for the support and the following steps: i) choosing an illumination wavelength ?; ii) choosing a material constituting the substrate and exhibiting, at illumination wavelength ?, a complex refractive index N0=n0?jk0 with k0?0.01; iii) choosing an ambient medium in contact with the layer on the side opposite to the substrate and exhibiting, at illumination wavelength ?, a complex refractive index N3=n3?jk3 with k3?0; iv) determining a nominal complex refractive index N1=n1?jk1 and a nominal thickness e1 of the layer wherein it behaves in the guize of antireflection layer when illuminated under normal incidence at illumination wavelength ?; and v) choosing a material constituting the layer and exhibiting, at illumination wavelength ?, a complex refractive index whose real and imaginary parts coincide with the nominal complex refractive index.

Abstract: The present invention relates to a metal-metal interdigitated photoconductive antenna that generates and/or detects terahertz waves, the photoconductive antenna comprising at least one substrate (1) and at least one electrode (2) on the front face of the substrate (1), wherein said photoconductive antenna comprises at least one layer (4) formed of a material reflective to terahertz waves, said layer (4) extending below the front face of the substrate (1) at a distance lower than the wavelength; and it comprises an interdigitated geometry on said front face of the substrate (1) comprising a first metallization layer of 5 nm Cr and 150 nm Au for the interdigitated electrodes (2), equally spaced by a distance ?, is made on said front face of the substrate (1); a 500 nm-thick layer of SiO2 (5) deposited over the first metallization layer; and a second metallic layer composed of metallic fingers (6) covering gaps with a periodicity double that of the distance ?.

Abstract: The present invention relates to methods and reagents for the treatment of melanoma and/or of metastatic melanoma that directly or indirectly target TYRP1 RNA transcript. The invention also relates to methods for predicting if a melanoma patient will be therapeutically responsive to such methods of treatment and reagents, and to methods for assessing the effectiveness of such methods of treatment and reagents. The invention further relates to a combination of biological markers that allows the prediction of melanoma patients' survival irrespective of the treatment administered.

Abstract: The present invention relates to novel amphiphilic dendrimers, hereafter denoted Dendri-TAC. The present invention also relates to perfluorocarbon nanoemulsions stabilized by these amphiphilic dendrimers and their uses for in vivo diagnostic and/or for therapy, notably as theranostic tools, for detection and/or treatment of cancer.

Abstract: The present invention relates to a new isolated polypeptide comprising an amino acid sequence having at least 94%, 95%, 99% or 100% identity to the full length amino acid sequence set forth in SEQ ID NO: 1, and having a polyester degrading activity, and uses thereof.

Abstract: A nucleic acid for the controlled expression of a nucleic acid encoding a pro-apoptotic protein in an individual, including: a regulatory polynucleotide including a minimal promoter and at least one AARE (amino acid response element) nucleic acid, the regulatory polynucleotide being activated in an individual upon consumption of a diet deficient in at least one essential amino acid; and a nucleic acid encoding a pro-apoptotic protein, which is placed under the control of the regulatory polynucleotide.

Abstract: A method for producing an MRI image includes the steps of acquiring lines of a volume under analysis using a steady-state gradient echo sequence in successive repetition times (TR); and applying an inhomogeneous magnetization transfer (ihMT) pre-saturation module (TMT) in each repetition time. The duration of the repetition times is greater than 20 milliseconds.

Abstract: The invention relates to a silicone composition comprising (a) crosslinked polymers comprising consecutive —Si—O— units containing exchangeable pendant bonds and exchangeable crosslinking points, that are exchangeable by aldehyde-imine exchange reactions and/or by imine-imine exchange reactions and/or by imine-primary amine exchange reactions, obtained by crosslinking linear or branched polymers comprising consecutive —Si—O— units and (b) monofunctional free aldehydes and/or monofunctional free imines and/or monofunctional free primary amines.

Abstract: An artificial neuron including: a membrane capacitor; an input of an external synaptic excitation in current, the membrane capacitor integrating the input current; a negative-feedback impulse circuit, supplied by a power supply at a negative voltage between ?200 mV and 0 mV and at a positive voltage between 0 mV and +200 mV, including: a bridge based on pMOS and nMOS transistors in series and linked by a midpoint to the membrane capacitor, the midpoint defining the output of the artificial neuron, at least one delay capacitor between the gate and the source of one of the transistors of the bridge, at least two CMOS inverters between the membrane capacitor and the gates of the transistors of the bridge.

Abstract: Method for visual tracking of at least one object represented by a cluster of points with which information is associated, characterised in that it includes steps to: receive (E1) data representing a set of space-time events, determine (E2) the probability that an event in the set belongs to the cluster of points representing the at least one object, for each event in the received set, determine (E3) whether or not an event belongs to the cluster of points as a function of the determined probability for the event considered, for each event in the received set, update (E4) information associated with the cluster of points for at least one object, for each event for which it was determined in the previous step that it belongs to the cluster of points, calculate (E4, E5) the position, size and orientation of the at least one object as a function of the updated information.

Abstract: A process for preparing a porous solid with an outer surface modified by at least one polymer; the polymer being simultaneously synthetized in solution and grafted on the outer surface of the solid, includes contacting: a porous solid; and a polymer-precursor solution comprising an adhesion primer, and at least one polymerizable monomer; under conditions enabling the formation of radical entities.

Abstract: The present invention relates to a novel process for preparing 3,5-bis substituted pyrazoles containing haloalkoxy- and haloalkylthio groups.

Abstract: The invention provides an assay-ready frozen eukaryotic cell (stored frozen) in a composition that includes a cryopreservative and an inhibitor of xanthine oxidase, a kit containing a plurality of the assay-ready frozen eukaryotic cell, and a method of preparation thereof to minimize the variability in the performance of the cell, particularly in terms of undesirable intra- and inter-assay variability.

Abstract: The present invention relates to multimeric mannosides, a process for preparing the same and their uses in medicine for treating Escherichia coli infections.

Abstract: The present invention provides nucleic acid, vectors, viruses, and recombinant cells comprising triple-stranded structures, such as those resulting from central initiation and termination of HIV-1 reverse transcription at the center of HIV-1 linear DNA genomes. These triplex structures can act as a cis-determinant of HIV-1 DNA nuclear import, allowing infection of non-dividing target cells. In one aspect, the presence of the DNA triplex sequence in an HIV vector strongly stimulates gene transfer in hematopoietic stem cells. The invention also provides methods of using these triplex structures for making recombinant cells, as well as methods of using the recombinant cells to express proteins of interest both in vitro and in vivo.