Patents Assigned to SCIENTIFIQUE (CNRS)
  • Modulation device comprising a nanodiode
    Patent number: 10340371
    Abstract: The invention relates to a modulation device created on a substrate (1), comprising at least one nanodiode in the form of a T fitted into a U, the channel (31) of said nanodiode being the leg of the T that is inserted into the U. The device is characterized in that it comprises at least one electrically conductive line (37) that passes over at least part of said channel (31).
    Type: Grant
    Filed: December 15, 2015
    Date of Patent: July 2, 2019
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE LILLE 1—SCIENCES ET TECHNOLOGIES
    Inventors: Christophe Pierre Paul Gaquiere, Guillaume Ducournau, Marc Faucher
  • Methods for in vitro investigating mitochondrial replication dysfunction in a biological sample, kits and uses thereof, therapeutic methods against progeroid-like syndromes or symptomes and screening method for identifying particular protease inhibitor(s) and/or nitroso-redox stress scavenger compound(s)
    Patent number: 10338082
    Abstract: The invention relates to a method for in vitro investigating mitochondrial replication dysfunction in a biological sample removed from a subject susceptible of suffering from physiological ageing or physiopathological conditions related to physiological ageing, or physiopathological ageing or associated symptoms or conditions, in particular premature ageing or accelerated ageing, or of a progeroid syndrome, such as Cockayne syndrome (CS), or neurodegenerative disorders or symptoms thereof, in which the levels of at least one species selected in the group of: POLG1 protein, POLG1 RNA, POLG2 protein, protease(s) which have POLG as a target, in particular serine protease(s) such as HTRA3 protein, HTRA2 protein and, HTRA3 RNA or HTRA2 RNA, or any combination of these species, are investigated.
    Type: Grant
    Filed: February 13, 2015
    Date of Patent: July 2, 2019
    Assignees: INSTITUT PASTEUR, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, COMMISSARIAT À L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
    Inventors: Laurent Arnaud Chatre, Miria Ricchetti, Alain Sarasin, Denis Biard
  • Methods and pharmaceutical compositions for the treatment and the prevention of cardiomyopathy due to Friedreich ataxia
    Patent number: 10337027
    Abstract: A method for preventing or treating cardiomyopathy due to energy failure in a subject in need thereof is provided. The method comprises administering to the subject a therapeutically effective amount of a vector which comprises a nucleic acid sequence encoding a gene that can reverse energy failure. An exemplary cardiomyopathy is that which is associated with Friedreich ataxia and an exemplary nucleic acid sequence comprises a nucleic acid that encodes frataxin (FXN).
    Type: Grant
    Filed: May 21, 2015
    Date of Patent: July 2, 2019
    Assignees: APHP (ASSISTANCE PUBLIQUE—HÔPITAUX DE PARIS), CORNELL UNIVERSITY, INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE M, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS, UNIVERSITÉ DE STRASBOURG
    Inventors: Helene Monique Puccio, Patrick Aubourg, Ronald G. Crystal, Pierre Bougneres
  • METHOD FOR PRODUCING POLYESTER POLYOLS AND USE THEREOF IN POLYURETHANE
    Publication number: 20190194380
    Abstract: A polyester polyol of formula produced by a first polycondensation (a) of a sugar alcohol Z in C3 to C8 and two diacids Y and Y? which are the same or different in C4 to C36, and a second polycondensation (b) of the product produced in (a) with two diols X and X? which are the same or different in C2 to C12, the polymer including such a polyester polyol. Also, a method for producing the polyester polyols and the use thereof in foams, adhesives, coatings or elastomers of polyurethane or polyisocyanurate.
    Type: Application
    Filed: August 24, 2017
    Publication date: June 27, 2019
    Applicants: TEREOS STARCH & SWEETENERS BELGIUM, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SOCIÉTÉ SOPREMA SAS, UNIVERSITÉ DE STRASBOURG
    Inventors: Pierre Etienne BINDSCHEDLER, Alexandru SARBU, Stephanie LAURICHESSE, Remi PERRIN, Pierre FURTWENGLER, Luc AVÉROUS, Andreas REDL
  • RIGID FOAM COMPRISING A POLYESTER POLYOL
    Publication number: 20190194379
    Abstract: A rigid foam or a composition allowing a rigid foam to be obtained, including a polyester polyol or a polymer including a polyester polyol, the polyester polyol being obtained by a first polycondensation (a) of a C3 to C8 sugar alcohol Z and two identical or different C4 to C36 diacids Y and Y? and a second polycondensation (b) of the product obtained in (a) with two identical or different C2 to C12 diols X and X?.
    Type: Application
    Filed: August 24, 2017
    Publication date: June 27, 2019
    Applicants: TEREOS STARCH & SWEETENERS BELGIUM, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SOCIÉTÉ SOPREMA SAS, UNIVERSITÉ DE STRASBOURG
    Inventors: Pierre Etienne BINDSCHEDLER, Alexandru SARBU, Stephanie LAURICHESSE, Remi PERRIN, Pierre FURTWENGLER, Luc AVÉROUS, Andreas REDL
  • FLEXIBLE OR SEMI-FLEXIBLE FOAM COMPRISING A POLYESTER POLYOL
    Publication number: 20190194378
    Abstract: A flexible or semi-flexible foam, or a composition making it possible to obtain a flexible or semi-flexible foam, including a polyester polyol or a polymer comprising a polyester polyol. The polyester polyol is obtained by a first polycondensation (a) of an alcohol sugar Z in C3 to C8 and of two identical or different diacids Y and Y? in C4 to C36 and a second polycondensation (b) of the product obtained in (a) with two identical or different diols X and X? in C2 to C12.
    Type: Application
    Filed: August 24, 2017
    Publication date: June 27, 2019
    Applicants: TEREOS STARCH & SWEETENERS BELGIUM, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SOCIÉTÉ SOPREMA SAS, UNIVERSITÉ DE STRASBOURG
    Inventors: Pierre Etienne BINDSCHEDLER, Alexandru SARBU, Stephanie LAURICHESSE, Remi PERRIN, Pierre FURTWENGLER, Luc AVÉROUS, Andreas REDL
  • Boronic polymer crosslinking
    Patent number: 10329414
    Abstract: The object of the invention is polymer compositions comprising cross-linked polymer comprising boronic ester functions enabling exchange reactions, as well as free monofunctional boronic esters. The compositions are obtained from the modification of a polymer by a functionalized boronic ester additive. This polymer can be pre-functionalized boronic ester or functionalized on addition of the said additive. In particular, the invention relates to a process enabling the behavior of a polymer to be modified by addition of a functional additive, enabling a cross-linked network containing exchangeable boronic ester links to be formed.
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: June 25, 2019
    Assignees: ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Ludwik Leibler, Renaud Nicolay, Max Rottger
  • Method for controlling a plurality of functional modules including a multi-wavelength imaging device, and corresponding control system
    Patent number: 10330911
    Abstract: A method is proposed for driving a plurality of functional modules included in a multi-wavelength microscopy imaging device. The device includes at least one first functional module and a second functional module, adapted respectively to performing a first function and a second function. The method includes at least one iteration of the acts of: sending a first driving signal to the second functional module when the first functional module has performed said first function; the second functional module triggers the function upon reception of the first driving signal; sending a second driving signal to the first functional module when the second functional module has performed said second function; the first functional module triggers said first function upon reception of the second driving signal.
    Type: Grant
    Filed: March 23, 2015
    Date of Patent: June 25, 2019
    Assignees: CNRS—CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE RENNES 1
    Inventors: Julien Roul, Marc Tramier, Jacques Pecreaux
  • Method for adjusting the level of inhibitors in an oil or gas well
    Patent number: 10329879
    Abstract: A method for adjusting, to a pre-determined value, the level of a mineral deposition or corrosion inhibitor injected into a gas or oil well. Using of the time-resolved fluorescence method for detecting and quantifying a mineral deposition or corrosion inhibitor in a fluid from an oil or gas production well.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: June 25, 2019
    Assignees: TOTAL SA, UNIVERSITE LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS
    Inventors: Christian Hurtevent, Salima Baraka-Lokmane, John-Richard Ordonez-Varela, Olivier Tillement, Thomas Brichart, Matteo Martini
  • Quinoline derivative for use in the treatment and prevention of viral infections
    Patent number: 10329317
    Abstract: The present invention relates to a quinoline derivative of formula (1) or one of its pharmaceutically acceptable salts. The present invention further relates to said quinoline derivative for medicament and for use in the treatment or prevention of a viral or retroviral infection and in particular AIDS or an AIDS-related condition or Human Immunodeficiency virus (HIV). The present invention also relates to a pharmaceutical composition comprising said quinoline derivative and to the process for preparing it as to a novel intermediate compound.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: June 25, 2019
    Assignees: ABIV AX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT CURIE, UNIVERSITE DE MONTPELLIER
    Inventors: Didier Scherrer, Aude Garcel, Noelie Campos, Jamal Tazi, Audrey Vautrin, Florence Mahuteau, Romain Najman, Pauline Fornarelli
  • Terahertz laser, terahertz source and use of such a terahertz laser
    Patent number: 10333267
    Abstract: A terahertz laser suitable for emitting at least one first electromagnetic radiation, a first emission frequency of which is between 700 and 1200 GHz. The laser comprises an infrared laser source and a resonant cavity arranged to be optically pumped by the infrared laser source, the resonant cavity containing ammonia gas as an amplifier medium and having at least one configuration in which the resonant cavity is a resonant cavity at the first emission frequency. The infrared laser source is a continuous semiconductor laser source capable of exciting molecules of the amplifier medium from an initial energy level to at least one first excited energy level, the molecules of the amplifier medium placed in the first energy level being able to relax through a pure inversion transition for which the relaxation energy corresponds to the first emission frequency.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: June 25, 2019
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE LILLE
    Inventors: Jean-François Lampin, Antoine Pagies
  • Materials coated with calixarenes
    Patent number: 10329232
    Abstract: A calixarene directly grafted onto the surface of a material, a related grafting process, and certain calixarene intermediates useful for carrying out the grafting process.
    Type: Grant
    Filed: March 28, 2013
    Date of Patent: June 25, 2019
    Assignees: UNIVERSITE LIBRE DE BRUXELLES (ULB), CENTER NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS, UNIVERSITE DE RENNES 1, UNIVERSITE PARIS DESCARTES
    Inventors: Ivan Jabin, Alice Mattiuzzi, Corlnne Lagrost, Philippe Hapiot, Olivia Reinaud
  • Transparent autophotorechargeable electrochemical device
    Patent number: 10333181
    Abstract: A transparent photorechargeable electrochemical device is provided. An n-type semiconductor may be used as a positive-electrode active material in the transparent photorechargeable electrochemical device. A method for photorecharging the device is also provided.
    Type: Grant
    Filed: November 27, 2014
    Date of Patent: June 25, 2019
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE PICARDIE JULES VERNE, SORBONNE UNIVERSITE
    Inventors: Frederic Sauvage, Christian Andriamiadamanana, Christel Laberty
  • SYSTEM AND METHOD FOR PRODUCING AN OPTICAL MASK FOR SURFACE TREATMENT, AND SURFACE TREATMENT PLANT AND METHOD
    Publication number: 20190187554
    Abstract: The invention relates to a system (2) for producing an optical mask (35) for surface treatment, in particular surface microtexturing, said system (2) comprising: a layer of material (20) which has an outer surface (21) that is exposed to the outside environment; and a generating and depositing device for generating and depositing droplets (30) on the outer surface (21) of the layer of material (20) in which a specific arrangement (31), forming the optical mask (35) on the outer surface (21) of the layer of material (20). The invention also relates to a treatment plant comprising a system (2) of said type. The invention further relates to a method for producing a mask as well as to a method for surface treatment.
    Type: Application
    Filed: June 21, 2017
    Publication date: June 20, 2019
    Applicants: H.E.F., UNIVERSITE JEAN MONNET SAINT ETIENNE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Maxime BICHOTTE, Yves JOURLIN, Laurent DUBOST
  • SYSTEM AND METHOD FOR PRODUCING AN OPTICAL MASK FOR SURFACE MICROTEXTURING, AND SURFACE MICROTEXTURING PLANT AND METHOD
    Publication number: 20190187567
    Abstract: The invention relates to a system (2) for producing an optical mask (35) for surface microtexturing, said system (2) comprising: a substrate (10) having a surface (11) that is to be textured; a layer of material (20) which covers the surface (11) of the substrate (10) and has an outer surface (21) that is exposed to the outside environment; and a generating and depositing device for generating and depositing droplets (30) on the outer surface (21) of the layer of material (20), in a specific arrangement (31) under condensation, forming the optical mask (35) on the outer surface (21) of the layer of material (20). The invention also relates to a treatment plant comprising a system (2) of said type. The invention further relates to a method for producing a mask as well as to a surface microtexturing method.
    Type: Application
    Filed: June 21, 2017
    Publication date: June 20, 2019
    Applicants: H.E.F., UNIVERSITE JEAN MONNET SAINT ETIENNE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Maxime BICHOTTE, Yves JOURLIN, Laurent DUBOST
  • AMPHIPHILIC MOLECULES LAYERS
    Publication number: 20190183799
    Abstract: The disclosure relates to a layer comprising at least one hydrophilic part and at least one hydrophobic part, the layer comprising self-assembled amphiphilic molecules polymerized with each other on both the hydrophilic part and the hydrophobic part of the layer; a detecting device comprising a substrate and the above-mentioned layer; and a liposome, a micelle, transport system for a substance and a biomimetic system comprising the above-mentioned layer. The disclosure also relates to a process for producing a layer, the process comprising: providing amphiphilic molecules; allowing sufficient time for the amphiphilic molecules to self-assemble and form at least one hydrophilic part and at least one hydrophobic part of the layer; polymerizing the self-assembled amphiphilic molecules with each other on both the hydrophilic part and the hydrophobic part of the layer.
    Type: Application
    Filed: October 13, 2016
    Publication date: June 20, 2019
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNR S, Université d'Aix-Marseille
    Inventors: Ahmad Kenaan, Anne Magali Charrier, Sébastien Lavandier, Jean-Manuel Raimundo
  • Methods and pharmaceutical compositions for the treatment of ischemic conditions
    Patent number: 10322162
    Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of ischemic conditions. In particular, the present invention relates to a method of treating an ischemic condition in a subject in need thereof comprising administering the subject with a polypeptide comprising an amino acid sequence having at least 70% of identity with the amino acid sequence ranging from the amino acid residue at position 186 to the amino acid residue at position 406 in SEQ ID NO: 1.
    Type: Grant
    Filed: January 6, 2016
    Date of Patent: June 18, 2019
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), COLLEGE DE FRANCE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE PARIS-EST CRETEIL VAL DE MARNE, ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS (APHP), ECOLE NATIONALE VETERINAIRE D'ALFORT (ENVA)
    Inventors: Stéphane Germain, Alain Berdeaux, Renaud Tissier, Bijan Ghaleh-Marzban, Catherine Monnot, Ariane Galaup
  • Use of novel compounds as negative electrode active material in a sodium-ion battery
    Patent number: 10326130
    Abstract: Precursor compounds of sodium alloy(s), for use as negative electrode active material in a sodium-ion battery, as well as to a negative electrode have the precursor compound of sodium alloy(s), as well as a sodium-ion battery having a negative electrode of this kind.
    Type: Grant
    Filed: June 16, 2014
    Date of Patent: June 18, 2019
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE MONTPELLIER
    Inventors: Laure Monconduit, Ali Darwiche, Julien Fullenwarth, Lorenzo Stievano, Moulay Tahar Sougrati
  • Biotechnological manufacture of vetiveryl esters
    Patent number: 10323210
    Abstract: The invention relates to a vetiveryl ester comprising at least 0.5 weight percent of secondary alcohol compounds with respect to the total weight of the vetiveryl ester and to a process for the preparation a vetiveryl ester, the process comprising: providing a vetiver oil, at least one enzyme preparation and at least one acylating compound; and allowing sufficient time for the enzyme preparation to esterify the alcohol compounds of the vetiver oil with the acylating compound. The invention also relates to a vetiveryl ester obtainable by the above process, a fragrance composition comprising an above-mentioned vetiveryl ester and the use of an above-mentioned vetiveryl ester for the preparation of a perfumed product.
    Type: Grant
    Filed: May 30, 2016
    Date of Patent: June 18, 2019
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS, UNIVERSITÉ DE NICE-SOPHIA ANTIPOLIS
    Inventors: Sylvain Antoniotti, Jean-Jacques Filippi, Irene Notar Francesco, Jade Ramilijaona
  • Method of diagnosis, prognostic or treatment of neurodegenerative disease
    Patent number: 10324096
    Abstract: Methods for the diagnosis and prognosis of neurodegenerative diseases, such as Alzheimer's disease, are described. Compositions and method for the treatment of neurodegenerative diseases are also described.
    Type: Grant
    Filed: June 29, 2016
    Date of Patent: June 18, 2019
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PARIS-EST CRETEIL VAL DE MARNE, SORBONNE UNIVERSITÉ, ICM-INSTITUT DU CERVEAU ET DE LA MOELLE EPINIERE, OTR3, ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS
    Inventors: Dulce Papy-Garcia, Minh Bao Huynh, Nadia Soussi-Yanicostas, Rita Vozari, Fernando Sineriz, Constantin Yanicostas