Abstract: Inadvertent or unavoidable contact of an acid with an acid-reactive substance may preclude the acid's use in another location where its reactivity is more desired. Excessive reactivity of acids toward acid-reactive substances may lead to undesired effects such as surface erosion, matrix deconsolidation, scaling, and the like. Methods for protecting an acid-reactive surface from excessive reaction may comprise: depositing a protective coating comprising an N-(phosphonoalkyl)iminodiacetic acid or any salt thereof onto an acid-reactive surface; and contacting a mineral acid or an organic acid with the protective coating without substantially reacting the acid-reactive surface.

Abstract: Disclosed is a screen packer assembly for use in filtering hydrocarbons in a wellbore at a subterranean location. The screen-packer assembly connects in a production tubing string and packs off the wellbore and provides an axial filter path for hydrocarbons through the assembly and into the productions tubing.

Abstract: The invention provides methods of treating or preventing malaria comprising administering to an animal an effective amount of a compound of formula I: Q-Y—R1—R2??(I), wherein Q, Y, R1, and R2 are as described herein. Methods of inhibiting a plasmodial surface anion channel of a parasite in an animal are also provided. The invention also provides pharmaceutical compositions comprising a compound represented by formula I in combination with any one or more compounds represented by formulas II, V, and VI. Use of the pharmaceutical compositions for treating or preventing malaria or for inhibiting a plasmodial surface anion channel in animals including humans are also provided. Also provided by the invention are clag3 amino acid sequences and related nucleic acids, vectors, host cells, populations of cells, antibodies, and pharmaceutical compositions.

Abstract: A system and method of conducting a computer-based, simultaneous, multiple round, descending clock auction for basic generation services (BGS) includes receiving bids by an application server host application for processing bids according to auction rules, for tranche units of BGS products, calculating next round prices, and sending round results to bidders, the subsequent round prices and a notice of the number of tranches bid during the previous round and/or the amount of excess supply offered. When available to a bidder, an extension request may be automatically granted extending the duration of the round and allowing all qualified bidders to submit new bids, and thereafter deducting the number of extensions available to the bidder. When the number of tranches bid are equal to or less than a certain threshold for each of the products, the auction may end and bidders are awarded an ending price for each of the products won.

Abstract: Methods and systems read a computer readable code on a printed vehicular violation using an optical sensor of a portable computing device and access a vehicular violation database to identify a registered vehicle corresponding to data in the computer readable code. The methods and systems retrieve a vehicular violation history for the registered vehicle. The vehicular violation history is a history of vehicular violations maintained by the vehicular violation database related to the registered vehicle, and includes a payment status of fines associated with the vehicular violations. The methods and systems therefore display this vehicular violation history and display an option to pay one or more of the fines on the graphic user interface. The methods and systems then receive payment information into the graphic user interface, and process the payment of one or more of the fines through the portable computing device, using the payment information provided.

Abstract: A method and a system for detecting sentiment of a human based on an analysis of human speech are disclosed. In an embodiment, one or more time instances of glottal closure are determined from a speech signal of the human. A voice source signal based on the determined one or more time instances of glottal closure is generated. A set of relative harmonic strengths is determined based on one or more harmonic contours of the voice source signal. The RHS is indicative of a deviation of the one or more harmonics of the voice source signal from a fundamental frequency of the voice source signal. A set of feature vectors is determined based on the RHS. The set of feature vectors are utilizable to detect the sentiment of the human.

Abstract: Described herein is a method of identifying a monoclonal antibody (or antigen-binding fragment thereof) that specifically binds a plurality of lyssaviruses for use in post-exposure rabies prophylaxis or in the treatment of clinical rabies. The method includes using a naïve antibody phage display library to screen for phage clones that bind whole recombinant rabies virus or cells expressing glycoprotein from multiple lyssaviruses (such as RABV, MOKV and WCBV) and/or specifically bind recombinant glycoprotein from different lyssaviruses.

Abstract: In some aspects, flow path connection conditions are generated for a flow path intersection in a one-dimensional fluid flow model. The one-dimensional fluid flow model represents a flow of well system fluid in a well system environment. The flow path connection conditions conserve fluid momentum among three or more flow path branches that meet at the flow path intersection. Fluid flow is simulated in the fracture network by operating the one-dimensional fluid flow model based on the connection condition.

Abstract: A method of hydraulically activating a mechanically operated wellbore tool in a bottom hole assembly includes: holding moveable elements of the wellbore tool in an unactivated position using a shear pin; inserting one or more drop balls into a drilling fluid; and flowing the drilling fluid with the drop balls to a flow orifice located in or below the wellbore tool. The flow orifice is at least partially plugged with the drop balls to restrict fluid flow and correspondingly increases the hydraulic pressure of the drilling fluid. The hydraulic pressure is increased to a point beyond the rating of the shear pin, thereby causing the shear pin to shear and allowing the moveable elements of the tool to move to an activated position.

Abstract: The present invention provides a CpG oligonucleotide prodrug that includes a thermolabile substituent on at least one nucleotide thereof. The present invention also provides compositions that include a carrier and a therapeutically effective amount of at least one CpG oligonucleotide prodrug. The present invention further provides therapeutic methods of using such thermolabile CpG oligonucleotide prodrugs and compositions thereof. The present invention further provides a method of inhibiting tetrad formation in a CpG oligonucleotide by functionalizing the CpG oligonucleotide with one or more thermolabile substituents.

Abstract: A formation tester for use in a subterranean well can include a probe which extends outward into contact with an earth formation, and an adjustable flow control device which limits an extension pressure applied to extend the probe. A method of testing a subterranean formation can include positioning a formation tester in a wellbore, extending a probe of the formation tester outward into contact with the formation, and limiting a force applied by the probe to the formation, the limiting being performed by variable actuation of a flow control device downhole. Another formation tester can include a probe which extends outward into contact with an earth formation, with a force applied by the probe to the formation being remotely adjustable downhole.

Abstract: One example of correlating energy to mix well cement slurry under laboratory conditions to field conditions can be implemented as a method to determine energy to mix cement slurry. Electrical power supplied to an electric mixer in mixing a specified well cement slurry is measured. An energy to mix the specified well cement slurry is determined from the measuring. The determined energy to mix the specified well cement slurry and specifications of field equipment for use in mixing the specified well cement slurry at a well site are compared. The field equipment is a different configuration than the electric mixer. Based on the comparing, it is determined whether the well cement slurry needs redesigning according to capabilities of the field equipment.

Abstract: A wheel hub removal tool is provided that allows a single technician to readily remove the hub using the vehicle steering. The tool is a generally U-shaped bracket that is seated on the ball-joint to support a pair of arms on opposite sides of the U-joint assembly. The arms carry corresponding blocks that are sized to seat between the drive axle housing and a component of the U-joint that is coupled to the wheel hub. The tool maintains a block on either side of the U-joint assembly so that pressure may be applied alternatively between the blocks to gradually dislodge the wheel hub from the axle. The tool is adjustable to accommodate different axle hub and bearing assembly configurations for different vehicles.

Abstract: A collective matrix is constructed, having a diagnostic sessions dimension and a diagnostic state descriptors dimension. The diagnostic state descriptors dimension includes a plurality of symptom fields, a plurality of root cause fields, and a plurality of solution fields. Collective matrix factorization of the collective matrix is performed to generate a factored collective matrix comprising a sessions factor matrix embedding diagnostic sessions and a descriptors factor matrix embedding diagnostic state descriptors. An in-progress diagnostic session is embedded in the factored collective matrix. A symptom or solution is recommended for evaluation in the in-progress diagnostic session based on the embedding. The diagnostic state descriptors dimension may further include at least one information field storing a representation (for example, a bag-of-words representation) of a semantic description of a problem being diagnosed by the in-progress diagnostic session.

Abstract: A computer operations center that has a number of computing systems, where each computing system issues system messages regarding such computing system. Each issued system message from each computing system is stored in a message logging database. The system messages stored in the message logging database are monitored for predetermined patterns, and upon detecting a particular pattern in the system messages, a predetermined action corresponding to the detected pattern is taken. The detected pattern anticipates an occurrence of an unwanted system event, and the corresponding action is intended to prevent or at least minimize the unwanted system event.

Abstract: A computer-implemented method for dialog state tracking employs first and second latent variable models which have been learned by reconstructing a decompositional model generated from annotated training dialogs. The decompositional model includes, for each of a plurality of dialog state transitions corresponding to a respective turn of one of the training dialogs, state descriptors for initial and final states of the transition and a respective representation of the dialog for that turn. The first latent variable model includes embeddings of the plurality of state transitions, and the second latent variable model includes embeddings of features of the state descriptors and embeddings of features of the dialog representations. Data for a new dialog state transition is received, including a state descriptor for the initial time and a respective dialog representation. A state descriptor for the final state of the new dialog state transition is predicted using the learned latent variable models.

Abstract: A system includes a tool for measuring properties of a formation. The tool includes a tool body, a neutron source to emit neutrons disposed within the tool body, a neutron detector disposed within the tool body spaced apart from the neutron source, and a neutron shield arranged in operational relationship to the neutron detector, the neutron shield defines an exterior surface and an interior volume, the neutron shield to prevent neutrons having an energy below a first predetermined threshold from traveling from the exterior surface to the interior volume. The neutron shield is movably coupled to the tool body, wherein the neutron shield defines a non-occluded position relative to the neutron detector such that the neutron detector is at least partially outside the interior volume, and the neutron shield defines an occluded position relative to the neutron detector such that the neutron detector is disposed within the interior volume.

Abstract: Embodiments of the present invention provide a folding carton designed to accept a retractable panel. The retractable panel may contain written information that should stay with or otherwise connected to the packaging, rather than on a folded leaflet inserted inside the carton that may be displaced. The panel may be pulled from its fully inserted/retracted position (within the carton) out to an extended position, where the panel displays the information. Even in the extended position, however, the panel stays secured with the carton.

Abstract: Various embodiments include apparatus and methods to detect and locate conductive bodies and/or provide steam-assisted gravity drainage (SAGD) steering operation. Tools can be configured with receiving sensors (310) arranged to cancel substantially a primary signal associated with a probe signal without rotating the receiving sensors to cancel the primary signal and to capture a secondary signal generated from a conductive body (301) below the earth's surface. Additional apparatus, systems, and methods are disclosed.