Abstract: Well tools utilizing swellable materials. Actuators for well tools may incorporate swellable materials as force generating devices. A well tool includes an actuator which actuates the well tool in response to contact between a swellable material and a well fluid. A method of actuating a well tool includes the steps of: installing a well tool including an actuator; contacting a swellable material of the actuator with a well fluid; and actuating the well tool in response to the contacting step. A well system includes a well tool with a flow control device and a swellable material. The well tool is operative to control flow through a passage of a tubular string in response to contact between the swellable material and well fluid.

Abstract: Metal chelators of Formula I and Formula II are disclosed: or a pharmaceutically acceptable salt thereof. Also disclosed are metal chelator-targeting moiety complexes, metal chelator-targeting moiety-metal conjugates, kits, and methods of their preparation and use in diagnosis and/or treatment of diseases and conditions, including, inter alia, cancer and thrombosis.

Abstract: The present disclosure provides compositions for eliciting an immune response, including a prophylactic immune response, against human immunodeficiency virus. The composition includes nucleic acid constructs encoding HIV antigenic polypeptides of multiple clades or strains. Methods for eliciting an immune response by administering the composition to a subject are also provided.

Abstract: Inhibitors of the soluble epoxide hydrolase (sEH) are provided that incorporate multiple pharmacophores and are useful in the treatment of diseases.

Abstract: A patient support apparatus includes a base, a frame coupled to the base, a deck supported by the frame and capable of moving relative to the frame, and a siderail assembly movable between a raised position above the deck and a first lowered position below the deck. The patient support apparatus further includes a siderail mover coupled to the deck to move the siderail assembly from the first lowered position to a second lowered position in response to movement of the deck relative to the frame.

Abstract: An ultrahigh-resolution fiber-optic confocal microscope has an illumination system; three single-mode optical fibers, each optically coupled to a fiber coupler; a sample support stage arranged to receive illumination radiation from an end of one of the single-mode optical fibers; a detector arranged to receive output radiation from one of the single-mode optical fibers; and a lock-in amplifier electrically connected to the detector and the illumination system. The illumination system is adapted to provide illumination radiation that has a time-varying strength that is correlated with the detector by the lock-in amplifier.

Abstract: An inhibitive water-based polymer mud system and method for using the system in drilling and in stabilizing wellbores is disclosed for use in water sensitive formations as an alternative to oil-based muds. The system comprises a fresh water or salt water base thinned or dispersed with a water soluble, biodegradable polyamide-based copolymer having at least one grafted side chain formed from ethylenic unsaturated compounds. This system is effective and has stable rheology over a broad pH range, even at a near neutral pH of 8.0. The drilling fluids do not contain heavy metals and are rheologically tolerant to contaminants such as cement, anhydrite and sodium and temperatures as high as about 400° F.

Abstract: A display structure has a base with non-rotatable sides and rotatable sides containing a first part with and a second part, the parts fastened by a rotatable fastener; a post containing a first and second face, the two non-rotatable sides fastened to the lower end of the posts, and the rotatable sides fastened to the lower end of the posts, a rotatable fastener specially located so as to allow rotation of the parts in regards to the post; and a top with non-rotatable and rotatable sides, the non-rotatable sides of the top fastened to the top of the post, the rotatable side of the top fastened to the non-rotatable sides of the top with rotatable fastener, said rotatable fastener of the top are specially located to allow rotation of the parts in regards to the non-rotatable side.

Abstract: A computer-implemented method, a computer system, and a computer program product for synchronizing output of media data across a plurality of devices is provided. The computer-implemented method for synchronizing output of media data across a plurality of output devices may include providing a communication network between a media server and a plurality of output devices; and synchronously outputting media data files on the plurality of output devices, wherein the media data files are transmitted to the output devices from the media server in form of a data stream over different delivery networks.

Abstract: Systems and methods are described that provide for targeted distribution of messages through communication networks, such as the Internet, in private and confidential environments. Messages, such as advertisements, can be stored in a message database. In a secure environment, consumer profiles, such as medical records, can be mined to identify target consumers for a given message. Messages can be retrieved from the message database, encrypted, and conveyed to the identified target consumers without inappropriately revealing or disclosing private or confidential consumer data.

Abstract: Changes to spot blocks to be broadcast via terrestrial stations can cause paid spots to be removed from corresponding spot blocks on a streaming station. If the streaming station has other spot blocks that are under-filled, the bumped spots can be automatically placed in under-filled spot blocks, allowing the bumped to be placed in an under-filled spot block faster than if human intervention was required. A media traffic system can keep track of the bumped spots, and in response to a request by a media automation system, provide a list of potential spots available for inclusion in the under-filled spot blocks. The automation system selects desired spots for placement in under-filled spot blocks, and notifies the traffic system about which potential spots have been placed. The traffic system removes the spots from its list of available spots to prevent selected spots from being included in future responses.

Abstract: A substantially pure or isolated oligodeoxynucleotide of at least 10 nucleotides is disclosed, wherein the oligodeoxynucleotide comprised a sequence represented by either formula: 5? N1N2N3T-CpG-WN4N5N6 3? wherein the CpG motif is unmethylated, W is A or T, and N1, N2, N3, N4, N5, and N6 are nucleotides, or the formula: 5? RY-CpG-RY 3? wherein the central CpG motif is unmethylated, R is A or G, and Y is C or T, as well as an oligodeoxynucleotide delivery complex and a pharmacological composition comprising the present inventive oligodeoxynucleotide, and a method of inducing an immune response by administering the present inventive oligodeoxynucleotide to a host. In some embodiments, the oligodeoxynucleotide includes the nucleic acid sequences set forth as SEQ ID NO: 137.

Abstract: A hard composite composition comprises a binder, and a polymodal blend of matrix powder In an embodiment, the polymodal blend of matrix powder has at least one local maxima at a particle size of 30 ?m or less, at least one local maxima at a particle size of 200 ?m or more, and at least one local minima between a particle size of about 30 ?m to about 200 ?m that has a value that is less than the local maxima at a particle size of 30 ?m or less.

Abstract: An equalization valve that allows for continuous equalization of pressure above and below a sealing element is disclosed. The equalization valve includes a housing having a fluid passageway therethrough. The fluid passageway is fluidically continuous across a sealing element disposed on a mandrel. The mandrel is part of a sealing assembly that contains the sealing element. The equalization valve includes a valve plug moveable from an open position in which the valve plug is not engaged with the sealing mandrel to a seated position in which the valve plug is seated against the sealing mandrel. The valve plug defines a conduit, the conduit that provides for a minimal fluid flow across the sealing element, when the valve plug is seated against the sealing mandrel. The sealing element remains sealingly engaged against the wellbore while the plug is in the seated position and while minimal fluid flow is occurring.

Abstract: A combination of H5N1 influenza peptides that provide for H5N1 diagnosis with a high level of sensitivity and specificity is described.

Abstract: Methods for detecting one or more target bacteria in a test sample are provided. It is shown herein that photosensitizers combined with intense light exposure reduce fluorescing background due to non-bacterial particles. This permits detection of subsequently labeled target bacterial cells (e.g., using a fluorescently labeled antibody) against a largely black background. In particular examples, the methods include incubating the test sample in a growth medium that permits growth of bacteria present in the sample, contacting the sample with a photo-sensitizer; exposing the sample to light under conditions sufficient for the photo-sensitizer to photobleach contaminating non-bacterial particulates present in the sample. The bacteria can then be substantially separated from the sample, thereby generating an isolated bacterial sample. The method can also include contacting the isolated bacterial sample with a binding agent specific for the one or more target bacteria, and detecting the one or more target bacteria.

Abstract: A downhole tool system includes a first downhole tool and a second downhole tool. The first downhole tool includes a first controller operable to receive an actuation signal including a tone. The first controller actuates the first downhole tool if the tone is a first specified frequency and changes the first downhole tool to communicate the actuation signal to the second downhole tool if first downhole tool is not actuated in response to the actuation signal. A second downhole tool includes a second controller operable to receive the actuation signal. The second controller actuates the second downhole tool if the tone is a second specified frequency. The second frequency is different from the first frequency.

Abstract: The invention relates to a method for the acquisition of seismic data that uses sources operable to produce, when they are in a shooting station, seismic vibrations according to a sweep type shooting sequence, of predetermined duration and variable frequency. According to this method, the source and recording device clocks are synchronized, shooting is authorized for each of the sources at a series of predetermined shooting times tk,n, with k being an order number for a given source and n a source order number, between 1 and the number of sources Ns, and carried out on condition that the source is in a state to produce vibrations at such time tk,n, and the signals produced by the receivers are continuously recorded. The invention also relates to a system for seismic acquisition that implements this method.

Abstract: A die set for forming explosive charge liners from powdered material is provided. The die set comprises a die block defining a basin and a punch shaped to interact with the basin. The die block and the punch are configured to exclude powdered material from a center axis of the basin.

Abstract: A system is described for relative positioning of access points in a real time locating system. The system may include a memory, interface, and processor. The memory may store layout information for a work area which includes architectural and infrastructure attributes. The processor may determine a number of access points to position in the work area based on the architectural attributes. The processor may determine a placement of a test tag in the work area based on the infrastructure attributes. The processor may determine a positioning of the access points in the work area which substantially maximizes coverage and accuracy of locating the test tag in the work area. The processor may determine a repositioning of one of the access points when the coverage and accuracy do not satisfy a threshold. The processor may provide a graphical representation of the positioning of the access points, when the threshold is satisfied.