Abstract: Disclosed herein are compounds useful as two-photon tracers. Also, methods are provided for visualizing intracellular glucose uptake, screening anticancer agents, and diagnosing cancer using the compounds. They exhibit preferential uptake by cancer cells, penetrability sufficient to allow bright section images, high water solubility, high pH resistance and low toxicity in addition to applicability to living cells in deep tissues over a long period of time.
Type:
Grant
Filed:
September 7, 2010
Date of Patent:
January 21, 2014
Assignee:
SNU R&DB Foundation
Inventors:
Seung Bum Park, Bong Rae Cho, Hyang Yeon Lee, Jong Min Park
Abstract: The present invention relates to a nano-scale MOS device having a saddle structure. Particularly, the invention relates to a high-density, high-performance MOS device having a novel structure capable of improving the scaling-down characteristic and performance of the MOS device, in which a channel and gate structure is formed in the shape of a saddle. The inventive MOS device is mainly characterized in that a channel region is recessed, a gate insulating film and a gate electrode are formed on the surface and sides of the recessed channel, and the gate electrode is self-aligned with the recessed channel. Namely, in the disclosed MOS device, a portion of the insulating film around the recessed channel is selectively removed to expose the surface and sides of the recessed channel.
Abstract: The present invention relates to an optical film comprising a substrate on which an array of structures is formed, wherein a material having a different refractive index, absorbancy or reflectivity from that of a surface of the structures is partially coated on the surface of the structures, and a manufacturing method thereof. Specifically, the optical film according to one embodiment of the present invention may have a different transparency depending on the direction or can transmit light asymmetrically. Further, the optical film may be applicable to image devices, which need to change brightness or images depending on the angle of view or to display three-dimensional images.
Abstract: Provided are a white-emitting monomolecular compound using excited-state intramolecular proton transfer (ESIPT) characteristics, and an organic electroluminescence device and a laser device comprising same. The white-emitting monomolecular compound according to the present invention is prepared by covalently bonding at least two types of molecules which produce different colors and have excited-state intramolecular proton transfer (ESIPT) characteristics. The white-emitting monomolecular compound according to the present invention achieves white luminescence irrespective of the concentration thereof and of the state of the materials thereof, and therefore can be used in a variety of fields including an organic electroluminescence device and a laser device.
Abstract: The present disclosure relates to a probe capable of electrochemical and Raman spectroscopic monitoring wherein a Raman-active gold microshell having conductivity is attached to the tip of a glass microcapillary tube in which a conductive material is coated on an inner wall thereof by electroless plating. By coupling the probe with a system capable of moving the probe, the activities of various catalyst materials can be detected quickly and information of intermediate products moving from and adsorbed on the surface can be provided.
Abstract: Disclosed herein is a method of preparing a ternary oxide semiconductor compound, including the steps of: dissolving an inorganic salt source including Sn and an inorganic salt source including at least one selected from the alkali earth metal group consisting of Ba, Sr and Ca in a mixed solvent of water and hydrogen peroxide to form a mixed solution; precipitating the mixed solution by changing the PH thereof to obtain a precipitate and then aging the precipitate; and drying and then annealing the aged precipitate to prepare MSnO3 powder (here, M includes at least one selected from the group consisting of Ba, Sr and Ca). The method is advantageous in that a nanosized ternary oxide semiconductor compound having a uniform particle size distribution can be prepared.
Type:
Application
Filed:
July 11, 2012
Publication date:
January 16, 2014
Applicant:
SNU R&DB FOUNDATION
Inventors:
Kug Sun Hong, Seong Sik Shin, Jae Ho Suk, Sang Baek Park, Jong Hoon Park, In Sun Cho, Dong Wook Kim
Abstract: Disclosed is a method for producing ethanol from xylose using a recombinant Saccharomyces cerevisiae strain transformed to express a xylose reductase that uses NADH as a cofactor and a xylitol dehydrogenase that uses NAD+ as a cofactor, which are coupled with each other. The method provides an increase in ethanol yield and production efficiency, as compared to a control group, and enables production of ethanol at higher yield and high production efficiency by further eliminating acetaldehyde dehydrogenase which mediates production of acetic acid (by-product).
Abstract: The present invention relates to a network management system for analyzing Internet application traffic. An apparatus for Internet application traffic classification benchmark according to the present invention configures two or more Internet application traffic classifications in plug-in scheme to perform a benchmarking function for the performance of each Internet application traffic classification. The apparatus can provide an objective and accurate evaluation for each classification technology by aggregating various Internet application traffic classification technologies by the plug-in scheme.
Type:
Grant
Filed:
September 30, 2010
Date of Patent:
January 14, 2014
Assignee:
SNU R&DB Foundation
Inventors:
Su Chul Lee, Sung Ryoul Lee, Hyun Chul Kim, Chong Kwon Kim
Abstract: Provided are a white-emitting monomolecular compound using excited-state intramolecular proton transfer (ESIPT) characteristics, and an organic electroluminescence device and a laser device comprising same. The white-emitting monomolecular compound according to the present invention is prepared by covalently bonding at least two types of molecules which produce different colors and have excited-state intramolecular proton transfer (ESIPT) characteristics. The white-emitting monomolecular compound according to the present invention achieves white luminescence irrespective of the concentration thereof and of the state of the materials thereof, and therefore can be used in a variety of fields including an organic electroluminescence device and a laser device.
Abstract: Provided are a white-emitting monomolecular compound using excited-state intramolecular proton transfer (ESIPT) characteristics, and an organic electroluminescence device and a laser device comprising same. The white-emitting monomolecular compound according to the present invention is prepared by covalently bonding at least two types of molecules which produce different colors and have excited-state intramolecular proton transfer (ESIPT) characteristics. The white-emitting monomolecular compound according to the present invention achieves white luminescence irrespective of the concentration thereof and of the state of the materials thereof, and therefore can be used in a variety of fields including an organic electroluminescence device and a laser device.
Abstract: A changeable liquid lens array and a method of manufacturing the same. The changeable liquid lens array includes a substrate, a plurality of partition walls arrayed on the substrate and having a fluid travel path, cells defined by the plurality of partition walls, a first fluid comprised in the cells, a second fluid arranged on the first fluid, a first electrode arranged on at least one side surface of each of the partition walls, and a second electrode disposed to be separate from the partition walls. A shape of shape of an interface between the first fluid and the second fluid changes based on a voltage that is applied to the first electrode and the second electrode.
Abstract: A method for preparing [18F]fallypride is disclosed, which comprises a first step for trapping a fluorine-18 to a polymer ion exchange cartridge; a second step for extraction of fluorine-18 by inputting low base concentrations: 5.0˜25 ?L of 40% TBAHCO3 or K2.2.2./K2CO3 (5˜25 mg/0.5˜3.0 mg) as a phase-transfer catalyst in a mixture of alcohol/water (1.0/0.2 (v/v)) or alcohol as a solvent into the polymer ion exchange cartridge trapped by the fluorine-18; a third step for preparing a [18F]fallypride product by removing the solvent from the trapped fluorine-18, by inputting tosylate precursor in CH3CN as a solvent into a reactor and by reacting the same for 5˜35 minutes at 50˜120° C.; and a fourth step for preparing a pure [18F]fallypride by purifying the prepared [18F]fallypride product.
Type:
Grant
Filed:
March 4, 2010
Date of Patent:
January 7, 2014
Assignee:
SNU R&DB Foundation
Inventors:
Sang Eun Kim, Byung Chul Lee, Byung Seok Moon, Yu Kyeong Kim
Abstract: One aspect of the present invention relates to a drug delivery system comprising a layered structure where a drug layer and a biodegradable polymer layer for controlling the release of drugs are alternately laminated. The drug delivery system can easily control an in-vivo drug release rate and a release amount.
Type:
Application
Filed:
September 20, 2012
Publication date:
January 2, 2014
Applicant:
SNU R&DB FOUNDATION
Inventors:
Dong-Il Cho, Seok Jun Hong, Sang Min Lee, Jae Hyun Ahn, Hyoung Jung Yoo
Abstract: The present invention relates to a composition comprising a Ninjurin1 expression or activity inhibitor for the prevention and treatment of inflammatory disease. Ninjurin1 protein is specifically expressed in macrophages around blood vessels, increases cell-cell adhesion and cell-matrix adhesion, increases expressions of Wnt7b (Wingless-type MMTV integration site family, member 7B) and Ang2 (angiopoietin-2), but reduces expression of Ang1 to induce apoptosis of vascular endothelial cells. In addition, Ninjurin1 protein is up-regulated when inflammation is induced and induces iNOS expression as well as increased NO generation. Therefore, the Ninjurin1 protein expression or activation inhibitor can be effectively used as an active ingredient of a composition for the prevention and treatment of inflammatory disease.
Abstract: A titanium oxide nano tube material is configured so that crystal grains of a nano tube has a crystal structure oriented with the [001] direction of a tetragonal crystal system as a preferred direction. FWHM (Full Width at Half Maximum) of a rocking curve with respect to the (004) plane peak is 11.1 degrees to 20.3 degrees. The titanium oxide nano tube material has excellent photoelectric characteristics since the crystal grains of the nano tube are oriented with the (004) plane or the [001] direction of a tetragonal crystal system as a preferred direction.
Type:
Grant
Filed:
August 4, 2011
Date of Patent:
December 24, 2013
Assignee:
SNU R&DB Foundation
Inventors:
Sang-Wook Lee, Ik-Jae Park, Dong-Hoe Kim, Kug-Sun Hong, Gil-Sang Han, Hyun-Suk Jung
Abstract: The present invention is to provide a nanoparticle, which can be used effectively for Raman analysis based on very high amplification effect of electromagnetic signal by plasomonic coupling of nanogap formation inside thereof and high reproducibility, and which includes core and surrounding shell with nanogap formation between the same and the method of synthesis thereof. The present invention is also to provide the method for detecting the analyte using the above nanoparticle and the analyte detection kit including the above nanoparticle.
Type:
Application
Filed:
November 24, 2011
Publication date:
December 12, 2013
Applicants:
SNU R&DB FOUNDATION, KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Inventors:
Yung Doug Suh, Jwa Min Nam, Dong Kwon Lim, Ki Seok Jeon
Abstract: The invention includes a pharmaceutical composition comprising an expression or activity regulator of AKAP12 (A-kinase anchoring protein 12) as the active ingredient. The compositions of the invention are useful for treating central nervous system diseases. The invention further includes a method of treating central nervous system diseases using a pharmaceutical composition of the invention. The central nervous system diseases contemplated within the invention include post-traumatic stress syndrome, stroke, and spinal injury.
Abstract: The present invention relates to a method for calculating a thermal protection factor, wherein the method comprises the steps of: applying heat to a first area coated with a thermal protection material, and a second area not coated with the thermal protection material; measuring the respective saturation temperatures of the first area and second area; calculating a first energy by dividing the energy corresponding to the heat applied to the first area by the saturation temperature of the first area; calculating a second energy by dividing the energy corresponding to the heat applied to the second area by the saturation temperature of the second area; and calculating the thermal protection factor of a thermal protection material by dividing the first energy by the second energy or dividing the difference between the first energy and the second energy by the first energy.
Abstract: The present invention relates to a multiferroic material capable of freely controlling magnetic field size at room temperature, and to a method of manufacturing the same. Said multiferroic material includes hexaferrites containing magnetic iron ions partially substituted by non-magnetic ions. Said non-magnetic ions act to change the magnetic anisotropy of said hexaferrites.
Type:
Grant
Filed:
October 1, 2009
Date of Patent:
December 3, 2013
Assignee:
SNU R&DB Foundation
Inventors:
Kee-Hoon Kim, Yisheng Chai, Sae-Hwan Chun
Abstract: In the wireless mesh network including a sender, a receiver, and a plurality of access points disposed between the sender and the receiver, available transmission paths between the sender and the receiver are determined; transmission expected values are calculated for the transmission paths; and a transmission path having a minimum transmission expected value is set as an actual transmission path. The transmission expected value is a sum of expected transmission counts, which is a reciprocal of multiplication of forward transmission success rate and backward transmission success rate of a communication link between the nodes disposed on the transmission paths. When an access point can transmit a packet concurrently with another access point, the expected transmitted count is reduced by half.
Type:
Grant
Filed:
September 23, 2011
Date of Patent:
December 3, 2013
Assignee:
SNU R&DB Foundation
Inventors:
Young Myoung Kang, Chong Kwon Kim, Joon Soo Lee