Abstract: A method for detecting movements of a plurality of points (P) of a surface (21), comprising a measuring step during which an incident ultrasonic wave is emitted into the air towards the surface and an ultrasonic wave reflected into the air by the surface (21) is detected. During the measuring step, each measuring point is illuminated by the incident ultrasonic wave at a multiplicity of angles of incidence, and the reflected ultrasonic wave is detected by a network of receiving transducers (3) comprising a plurality of ultrasonic receiving transducers (3a). The movements of the surface are determined at a measuring point by determining a delay and/or a phase shift between two beam-forming signals for said measuring point.

Abstract: The present invention relates to a fusion protein comprising a Cas9 domain and a Spo11 domain, as well as the use of this protein to induce targeted meiotic recombinations in a eukaryotic cell.

Abstract: The present invention concerns a reactor for the conversion of carbon dioxide or carbon monoxide into hydrocarbon and/or alcohol comprising a support made from an electrically and thermally conductive material, forming the wall or walls of at least one longitudinal channel that passes through the support and also acting as the cathode of the reactor, at least one wire electrode forming an anode of the reactor, and extending within each longitudinal channel, and being arranged at a distance from the wall or walls of the longitudinal channel, each wire electrode optionally being covered with an electrically insulating layer along the part of the wire electrode extending within the longitudinal channel, a catalyst capable of catalysing a conversion reaction for the conversion of carbon dioxide or carbon monoxide into hydrocarbon and/or alcohol, the catalyst being situated between the wire electrode and the wall or walls of each longitudinal channel.

Abstract: Evaluation of the perception of colors by mammals with a view to obtaining a characteristic biomarker of each tested subject takes advantage of the slow pupillary oscillatory response to generate an objective neurological signature of this perception of colors. A method based on pupil frequency tagging is used at a tagging frequency Ftag adapted to the pupil response speed. A dynamic two-color stimulus is displayed, this stimulus comprising a two-color pattern the colors of which are inverted at the frequency Ftag, one of the colors gradually varying in a range of possible values. From the pupillary response, a signal representative of the oscillation power of the pupil is generated. The minimum of this signal corresponds to the relative iso-luminance of the tested pair of colors.

Abstract: The present invention relates to a compound of the following general formula (I); or a pharmaceutically acceptable salt and/or solvate thereof, for use as drug, particularly intended for inhibiting a programmed cell death route selected from the group consisting of ferroptosis, oxytosis and cellular necroptosis. The present invention also relates to a compound of general formula (I) for use as a drug for neuroprotection as well as for preventing and/or treating disorders associated with cellular necroptosis or ferroptosis. The present invention also relates to a pharmaceutical composition comprising a compound of general formula (I), or a pharmaceutically acceptable salt and/or solvate thereof. The present invention also encompasses the use of a compound of the general formula (I) for organs preservation.

Abstract: A positive electrode active material for a sodium-ion battery has the following formula: NaxNi0.5-yCuyMn0.5-zTizO2, in which: -x varies from 0.9 to 1; -y varies from 0.05 to 0.1; -z varies from 0.1 to 0.3. When z is equal to 0.1 and x is equal to 1, then y is not equal to 0.05.

Abstract: A method for monitoring a reaction and a reaction system are provided. The reaction system includes at least one vessel for the reaction medium, which is in fluid communication with an injection tube; at least one vessel for a carrier fluid that is immiscible with the reaction medium, which is in fluid communication with a reaction tube; the injection tube being mounted so as to lead into the reaction tube such that individual drops of the reaction medium can be injected into the reaction tube and into the immiscible carrier fluid, so as to form a train of reaction chambers; at least one detector for monitoring a reaction; a means for classifying the reaction chambers; and at least one means for recirculating reaction chambers in front of at least one detector for monitoring a reaction.

Abstract: This system for real-time localization of a millimetric or submillimetric object, such as a microrobot, in a viscoelastic medium, in particular in an organ of a subject such as a brain, a liver or a pancreas, includes: at least one bubble configured to be attached to said object, the or each bubble having a hermetic envelope filled with a gas; at least one ultrasound transducer configured to emit initial ultrasound signals and to detect deflected ultrasound signals deflected at the surface of the bubble(s); a processing unit in communication with the ultrasound transducers and configured to generate localization data of the object from localization data of the bubble(s) based on the deflected ultrasound signals detected by the ultrasound transducers.

Abstract: The disclosure relates to TSP-1-derived peptides capable of inducing immunogenic cell death, in particular immunogenic cancer cell death. It further relates to uses of such peptides, in particular to prepare a pharmaceutical composition to allow or improve the efficiency of a therapy of cancer in a subject in need thereof.

Abstract: A pharmaceutical compositions includes GLP-1 and GLP-1 analogues inducing an anabolic stimulation of chondrocytes and a decreasing in chondrocyte catabolic including a decrease in cartilage matrix loss and cartilage degeneration for use in the treatment of cartilage disease. The composition induces cartilage regeneration and anabolic stimulation of chondrocytes, including chondrocyte proliferation and/or stem cell differentiation into chondrocytes.

Abstract: The present disclosure relates to the use of a homeoprotein or a recombinant vector encoding said protein for treating or preventing DNA damage and/or cellular aging. In particular, the invention concerns the use of Engrailed for the treatment of Parkinson disease.

Abstract: An acousto-optic imaging method in which light waves and unfocused acoustic waves having various directions of propagation m are emitted in a medium, by spatially modulating the amplitude of the ultrasonic transducers of an array of transducers according to several periodic spatial amplitude modulations j, and the resulting optical signal Smj(t) is captured. For each direction of propagation m, the signals Smj(t) are spatially demodulated in order to determine a signal Sm(t) used to reconstruct the image of the medium.

Abstract: A bis-urea compound of general formula (IV): The compound is useful as a thermo-thickening agent in a non-polar liquid such as engine lubricating oil or thermosetting varnish. Also, a method for preparing the thermo-thickening compound. Further, a composition comprising the thermo-thickening compound and a non-polar liquid.

Abstract: A regenerative material in the connective tissues (such as bone, dentin or pulp) regeneration field. More precisely, a connective tissue regenerative material, preferably a bone, dentin or pulp regenerative material, including: a porous polymer matrix having interconnected pores; and non-hydrated calcium silicate particles; wherein: the polymer matrix is anhydrous; the non-hydrated calcium silicate particles have a d50granulometry, preferably ranging from 0.05 ?m to less than the average diameter size of the pores of the matrix; and the non-hydrated calcium silicate particles being coated on the inside walls of the pores of the matrix. Also, a method for preparing the connective tissue regenerative material and uses of the regenerative materials, such as in the dental field; especially, for providing regenerative materials with improved biomechanical and osteoinductive properties (i.e.

Abstract: Fluorescent labeling of proteins. In particular, membrane-impermeant fluorogenic chromophores being capable of binding reversibly a functional derivative of a Photoactive Yellow Protein (PYP), or a functional fragment thereof, for fluorescently labeling biological molecules of interest, preferably proteins of interest. Especially, 4-hydroxybenzylidene-rhodanine (HBR) analogs of formula (II) as membrane-impermeant fluorogenic chromophores.

Abstract: A bituminous compositions including at least one molecule of general formula (I) or (II), alone or in a mixture. Also relates to the use of these bituminous compositions in the fields of road applications, particularly in the production of road binders and roadways in general, as well as in the fields of industrial applications. Also relates to a method for preparing said bituminous compositions. Further relates to novel molecules of formula (I) or (II), alone or in a mixture, which can be used in particular in the formulation of bituminous compositions.

Abstract: A method for the generation of a consciousness indicator for a non-communicating subject, including generating a sensory stimulation involving at least one of the five senses, the sensory stimulation having multiple consecutive stimuli including at least a first stimulus and a second stimulus relating to the same sense and different from one another, measuring an electrocardiographic signal of the subject during the generation of the sensory stimulation, extracting at least one EKG feature from the electrocardiographic signal associated to cognitive processes and generating a consciousness indicator using the EKG features as input of a classifier.

Abstract: Disclosed are agents activating CD47 and their use in the treatment of inflammation, in particular non-resolving low grade inflammation, characterized by chronic MP infiltration, such as age-related macular degeneration. Also disclosed are pharmaceutical compositions, medicaments and kits including the agents.

Abstract: The present invention improves the quality of the magnitude and phase images produced in medical imaging, in particular in the case of multi-antenna MRI. The invention proposes to generate (28) such an image (I) by summing the complex image data (pj,{tilde over (p)}j) obtained from different antennas by weighting these data using only the diagonal elements (Rj,j) of an antenna noise covariance matrix or its inverse or pseudo-inverse matrix (Rj,j?1). A reference antenna (Ref) may be determined (24), so as to be able to replace (26), in each of these datum, a phase component specific to the acquisition antenna by a reference phase component. The reference antenna is preferably a virtual antenna formed by linear combination of the antennas of the MRI system. If significant improvements are obtained in the phase image resulting from the summation, a very clear gain is also surprisingly obtained in the magnitude image.

Abstract: The bituminous compositions comprising molecules of formula (I), (II) and/or (III) used in the fields of road applications, as well as in the fields of industrial applications, a method for producing the bituminous compositions and novel molecules that can be used in the formulation of bituminous compositions.