Patents Assigned to State University
  • Antisense antibacterial compounds and methods
    Patent number: 11142764
    Abstract: Provided are antisense oligomers targeted against bacterial mRNAs and other macromolecules associated with a biochemical pathway and/or cellular process, and related compositions and methods of using the oligomers and compositions to treat an infected mammalian subject, for example, as primary antimicrobials or as adjunctive therapies with classic antimicrobials.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: October 12, 2021
    Assignees: Board of Regents, The University of Texas System, Oregon State University
    Inventors: David Greenberg, Bruce L. Geller
  • Systems and methods for improved vehicular safety
    Patent number: 11142071
    Abstract: Embodiments of a system for improving automobile safety are disclosed.
    Type: Grant
    Filed: September 20, 2019
    Date of Patent: October 12, 2021
    Assignee: Arizona Board of Regents on Behalf of Arizona State University
    Inventor: Ashraf Gaffar
  • Metal-assisted delayed fluorescent emitters containing tridentate ligands
    Patent number: 11145830
    Abstract: Tridentate platinum, palladium, and gold complexes of Formulas A-I and A-II and tridentate iridium and rhodium compounds of Formulas B-I, B-II, and B-III suitable for delayed fluorescent and phosphorescent or phosphorescent emitters in display and lighting applications.
    Type: Grant
    Filed: August 14, 2020
    Date of Patent: October 12, 2021
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Jian Li, Guijie Li
  • Wireless multichannel neurostimulators and methods for using the same
    Patent number: 11141596
    Abstract: A micro-scale implantable bioelectronic medical device system that allows multichannel neurostimulation of peripheral nerve bundles so to affect a more localized and specific control over neuromodulation of body tissues and organs. Such systems can be used in medical therapeutic applications for the treatment of a wide variety of disorders of the human body and may be applied in the growing field of medical neuromodulation. Systems and processes may also provide a way of interfacing to nerve and muscle for purposes of the control of advanced robotic prosthetics as well as man-machine interfaces. Apparatus, systems and processes may be adapted in various embodiments to the stimulation of brain and other bioelectrically excitable tissues in the human body as well.
    Type: Grant
    Filed: February 13, 2019
    Date of Patent: October 12, 2021
    Assignee: Arizona Board of Regents on Behalf of Arizona State University
    Inventors: Bruce C. Towe, Jitendran Muthuswamy
  • Insect toxin delivery mediated by a densovirus coat protein
    Patent number: 11140902
    Abstract: A coat protein of Junonia coenia densovirus (JcDNV) is used to deliver attached peptide insect toxin across the gut epithelium of a fall armyworm, Spodoptera frugiperda. A fusion protein comprising VP4 attached to an insect toxin via a peptide linker is developed. A composition comprising a JcDNV coat protein attached to an insect toxin via a peptide linker can be used for insect pest control.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: October 12, 2021
    Assignees: University of Florida Research Foundation, Inc., Iowa State University Research Foundation, Inc.
    Inventors: Bryony C. Bonning, Mariah Kemmerer
  • High efficiency solid oxide fuel cell—internal combustion engine hybrid power system
    Patent number: 11145880
    Abstract: A hybrid stationary power generator is provided. The system is fueled from natural gas and based on SOFCs and high efficiency, internal combustion (IC) engine technologies is conceived to generate electric power at 100-kW scale with an efficiency of 71% and a capital cost of <900 $/kW. This novel system integrates a solid oxide fuel cell (SOFC) stack with a high efficiency stationary engine and balance-of-plant (BOP) equipment to create a hybrid power system.
    Type: Grant
    Filed: December 26, 2018
    Date of Patent: October 12, 2021
    Assignees: Colorado School of Mines, Colorado State University Research Foundaton
    Inventors: Robert Braun, Todd Bandhauer, Daniel Olsen, Bret Windom
  • MACHINE-LEARNING METHOD AND APPARATUS TO ISOLATE CHEMICAL SIGNATURES
    Publication number: 20210313016
    Abstract: A processing workflow centered on machine-learning algorithms that identifies a number of chemical features that can best distinguish the presence or absence of a chemical source. These chemical features are a chemical fingerprint that is unique to each source. The analysis workflow is rapid (e.g., fingerprints can be generated in minutes). The analysis workflow has wide-ranging applications such as detecting markers of pollution sources in rivers and fish tissues, forest pathogen outbreaks, and hard-to-diagnose diseases.
    Type: Application
    Filed: March 29, 2021
    Publication date: October 7, 2021
    Applicant: Oregon State University
    Inventor: Gerrad Jones
  • A METAL-REDUCING ENZYMATIC TAG FOR OPTICAL AND ELECTRON MICROSCOPY
    Publication number: 20210311066
    Abstract: Enzymes that reduce specific metal or metalloid ions to insoluble form are important to science. Peptides isolated from yeast- and phage-display libraries can affect the size and morphology of inorganic materials during their synthesis. Herein, an Se binding peptide was fused to an enzyme capable of reducing selenite (SeO32?) to a Se0 nanoparticle (SeNP). The fusion of the Se binding peptide to the metalloid reductase provided size control of the resulting SeNP. The SeNP product also remains associated to the enzyme fusion. The Se binding peptide fusion to the enzyme increases the enzyme's SeO32? reductase activity. Modification of enzyme activity was absent, and the size control of particles was diminished when the Se binding peptide was added exogenously to the reaction mixture. Binding of the peptide is attributed to His based ligation that results in a conformational change to the peptide.
    Type: Application
    Filed: August 9, 2019
    Publication date: October 7, 2021
    Applicant: Colorado State University Research Foundation
    Inventors: Christopher J. ACKERSON, Zachary BUTZ, Richard NEMETH, Ryan RISKOWSKI, Kanda BORGOGNONI
  • SYSTEMS AND METHODS FOR A POWER-GENERATING THERMOGALVANIC BRICK
    Publication number: 20210310244
    Abstract: Various embodiments of systems and methods for a thermogalvanic brick are disclosed.
    Type: Application
    Filed: October 18, 2019
    Publication date: October 7, 2021
    Applicants: Arizona Board of Regents on Behalf of Arizona State University, Kings College London, Newsouth Innovations PTY Limited
    Inventors: Patrick Phelan, Leigh Aldous, Robert Taylor, Benjamin Obeng
  • Nondestructive imaging using a split-ring resonator sensing apparatus
    Patent number: 11137359
    Abstract: A defect sensing apparatus is configured to identify defects or targets in materials. A further aspect of the defect sensing apparatus includes a reference split-ring resonator coupled to the microstrip. The defect sensing apparatus includes a reference split-ring resonator located on a reference side of the microstrip and a first sensing split-ring resonator located on a sensing side of the microstrip.
    Type: Grant
    Filed: February 26, 2020
    Date of Patent: October 5, 2021
    Assignee: Board of Trustees of Michigan State University
    Inventors: Lalita Udpa, Satish Udpa, Saptarshi Mukherjee
  • Minimally invasive microwave ablation device
    Patent number: 11135010
    Abstract: An electrosurgical device (10) is provided that is operable to deliver microwave energy within a controlled angular expanse to cause targeted tissue ablation. The device (10) comprises a blocking or reflecting material such as cylindrical members (34) that are laterally spaced from the antenna (20) that is operable to emit the microwave energy. The reflecting material creates regions in and/or surrounding the device into which sensors (51), such as thermocouple wires, may be placed to monitor a condition associated with the device or the patient's body.
    Type: Grant
    Filed: May 22, 2020
    Date of Patent: October 5, 2021
    Assignees: Precision Microwave Inc., Kansas State University Research Foundation
    Inventors: Austin Pfannenstiel, Hojjatollah Fallahi, Punit Prakash
  • Peptide hydrogel properties and its applications
    Patent number: 11135163
    Abstract: Peptide hydrogels having a self-assembling, 3-dimensional nanofiber matrix are described. The nanofiber matrix comprises an amphiphilic peptide and optionally albumin. The peptide comprises (consists of) a terminal hydrophobic region, a central turning region, and a terminal hydrophilic region. Methods of making such hydrogels are also described, along with methods of using the hydrogels as scaffolding for tissue engineering, hemostatic agents, as well as 3-dimensional cell cultures, and for drug delivery, encapsulation of active agents (therapeutic cells, molecules, drugs, compounds), cell transplantation, cell storage, virus culture and storage.
    Type: Grant
    Filed: August 22, 2018
    Date of Patent: October 5, 2021
    Assignee: Kansas State University Research Foundation
    Inventors: Xiuzhi S. Sun, Hongzhou Huang, Tiffany L. Carter, Mark L. Weiss
  • Live-cell seeding method for microarrays
    Patent number: 11136614
    Abstract: Methods for seeding live cells onto spatially defined regions of a substrate including multiple features (e.g., microwells or other microenvironments) utilize a stencil embodied in a hole-defining sacrificial film. A sacrificial film devoid of holes may be applied over features of a substrate, and a hole generating mechanism (e.g., hot needle or laser) aligned with features may be used to define holes in the film. Alternatively, holes may be predefined in a sacrificial film to form a stencil, and the stencil may be assembled to the substrate with the holes registered with features thereof. Thereafter, cells are seeded through holes in the film. Seeded cells are subject to incubation, further processing, and/or performance of one or more assays, and the hole-defining sacrificial film (stencil) may be removed.
    Type: Grant
    Filed: October 7, 2016
    Date of Patent: October 5, 2021
    Assignee: Arizona Board of Regents on Behalf of Arizona State University
    Inventors: Jacob Messner, Clifford Anderson, Honor Glenn, Kristen Lee, Mark Richards, Laimonas Kelbauskas, Kimberly Bussey, Deirdre Meldrum
  • IGA FC-folate conjugates, pharmaceutical compositions and methods to treat cancer
    Patent number: 11135302
    Abstract: IgA-based Fc-folate conjugates as a treatment for cancer are provided. The conjugates utilize only the Fc portion of IgA to target its receptor on neutrophils (Fc?R1) to elicit antibody-dependent cellular-cytotoxicity (ADCC).
    Type: Grant
    Filed: May 10, 2019
    Date of Patent: October 5, 2021
    Assignee: Wayne State University
    Inventor: Cecilia Speyer
  • Air cooled condensing heat exchanger system with acid condensate neutralizer
    Patent number: 11135547
    Abstract: An air-cooled condensing heat exchanger system (“ACHX”) installed in a fossil power plant flue gas treatment system recovers water and low temperature waste heat from boiler flue gas for advanced coal fired power plant applications. More particularly, the ACHX system recovers water from combustion flue gas by phase change. To recover water from flue gas, the ACHX system uses ambient air from an air intake installed on the stack to cool down the flue gas in the ACHX.
    Type: Grant
    Filed: September 30, 2017
    Date of Patent: October 5, 2021
    Assignee: Arkansas State University—Jonesboro
    Inventor: Kwangkook Jeong
  • Cyclopentene monomers and methods of polymerization
    Patent number: 11136426
    Abstract: Cyclopentene monomers and methods of polymerization, including the polymerization of the cyclopentene monomers. The cyclopentene monomers include allylic substituted cyclopentene monomers that may be racemic or enantiopure. The methods of polymerization may permit the resulting polymers to have one or more desirable structural features.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: October 5, 2021
    Assignee: Florida State University Research Foundation, Inc.
    Inventor: Justin G. Kennemur
  • Methods and compositions for prevention and treatment of Apicomplexan infections
    Patent number: 11135231
    Abstract: Methods and compositions for preventing and/or treating diseases and conditions caused by certain apicomplexan infections are provided. The methods involve administering/providing to a subject one or more of tartrolon D and E, including isomers thereof. Exemplary apicomplexan infections that are prevented/treated by the compounds of the invention include those caused by Cryptosporidium, Babesia, Cyclospora, Isospora, Plasmodium, Sarcocystis, Besnoitia, Hammondia, Neospora, Theileria and Toxoplasma.
    Type: Grant
    Filed: December 7, 2017
    Date of Patent: October 5, 2021
    Assignees: Washington State University, Tufts Medical Center, Inc., University of Utah
    Inventors: Roberta O'Connor, Eric W. Schmidt
  • Infra-sound array system for use in determining gun shots
    Patent number: 11137473
    Abstract: An acoustic goniometer device may include at least four microphones coupled to a collapsible structure. The device may further include a processor configured to receive at least four sound signals from the at least four microphones and to determine a direction of arrival of a sound event within three dimensions based on a time shift between the at least four sound signals. A method may include receiving at least four sound signals from at least four microphones coupled to a collapsible structure and determining a direction of arrival of a sound event within three dimensions based on a time shift between the at least four sound signals.
    Type: Grant
    Filed: March 16, 2020
    Date of Patent: October 5, 2021
    Assignee: Boise State University
    Inventors: Sin Ming Loo, Mark Laverty
  • Medication bottle with anti-tampering features
    Patent number: 11135131
    Abstract: A medication bottle includes an outer container wall, an inner container wall and a fluid, such as an aversive liquid, located between the walls. In another aspect, the fluid is located within separate compartments or channels located between the walls where the walls contact or are secured to each other. A further aspect provides a removeable cap including multiple sensors, at least one of which is a biometric sensor.
    Type: Grant
    Filed: September 13, 2019
    Date of Patent: October 5, 2021
    Assignees: Board of Trustees of Michigan State University, Board of Regents of the University of Nebraska
    Inventors: Bahar Aliakbarian, Muhammad Rabnawaz, Susan E. Selke, Krystal Cheng, Arun Ross, Austin Cozzo, Anurag Chowdhury, Ali Tamayol, Carina Russell, Prem Chahal
  • ULTRA-FAST OPTICAL MODULATION AND ULTRA-SHORT PULSE GENERATION BASED ON TUNABLE GRAPHENE-PLASMONIC HYBRID METASURFACES
    Publication number: 20210302763
    Abstract: An optical device is disclosed. The optical device includes a silicon substrate, an aluminum oxide layer, an aluminum layer between the silicon substrate and the aluminum oxide layer, and a metasurface nanostructure. The metasurface nanostructure may include a graphene monolayer on the aluminum oxide layer and an electrically conductive nanoantenna array in direct contact with the graphene monolayer, where each nanoantenna in the nanoantenna array may include multiple segments, each segment having one or more parameters selected to achieve simultaneous resonance in the mid-infrared and the near infrared spectral regions when the graphene monolayer is irradiated with a near infrared pump pulse and a continuous mid-infrared probe. The optical device generates mid-infrared pulses via ultrafast modulation of hot carriers in the monolayer graphene.
    Type: Application
    Filed: March 31, 2021
    Publication date: September 30, 2021
    Applicant: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Yu Yao, Ali Basiri