Abstract: Some embodiments include a method of operating a detection sensor array. The detection sensor array has multiple detection sensors. Each detection sensor of the multiple detection sensors has an enabled state and a disabled state, and each detection sensor of the multiple detection sensors is configured to detect and identify electromagnetic radiation when in the enabled state and not to detect and identify electromagnetic radiation when in the disabled state. The detection sensor array also has a test state in which all of the multiple detection sensors operate in the enabled state when the detection sensor array is in the test state. Other embodiments of related systems and methods are also disclosed.
Type:
Grant
Filed:
May 5, 2016
Date of Patent:
February 27, 2018
Assignee:
ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
Inventors:
Joseph Smith, Eric Forsythe, David Allee
Abstract: An apparatus includes an electroactive polymer member and a first electric terminal and a second electric terminal. The electroactive polymer member has a free portion configured to change position relative to a fixed portion in response to an external stimulus corresponding to at least one of a flow parameter or a fluid parameter. The first electric terminal and the second electric terminal are coupled to the electroactive polymer member. The first electric terminal and the second electric terminal provide an electrical signal in response to the change.
Type:
Grant
Filed:
April 28, 2011
Date of Patent:
February 27, 2018
Assignee:
BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
Inventors:
Guoming G Zhu, Xiaobo Tan, David Ling-Shun Hung
Abstract: An osseointegratable prosthetic device suitable for implantation via a one-step surgical process includes a threaded insertion end, an externally accessible tool interface end, and an intermediately arranged scaffold portion defining recesses that permit ingrowth of skeletal tissue. Such recesses may include multiple longitudinal fins as well as transverse ribs, which may embody or be coated with porous material to promote bone ingrowth. A split flange portion includes discontinuous portions and may permit pretensioning of the device. The device may be fabricated as a unitary body structure from thermoplastic materials using techniques such as fused filament fabrication (a form of 3D printing). The osseointegratable prosthetic device enables one-step surgical implantation without requiring separately implantable fixture/sleeve and abutment portions according to conventional osseointegratable prosthetics. Methods for fabricating an osseointegratable prosthetic device are further provided.
Type:
Application
Filed:
August 16, 2017
Publication date:
February 22, 2018
Applicant:
Arizona Board of Regents on behalf of Arizona State University
Abstract: A method for separating a homogeneous catalyst from a solution includes forming a host-guest compound between a first isomer of the catalyst and inclusion compound in the solution and isolating the host-guest compound from the solution. The catalyst may be released from the inclusion compound by converting the first isomer of the catalyst to a second isomer of the catalyst.
Type:
Application
Filed:
August 22, 2017
Publication date:
February 22, 2018
Applicant:
Florida State University Research Foundation, Inc.
Abstract: The orthogonal space random walk (OSRW) algorithm is generalized to be the orthogonal space tempering (OST) method via the introduction of the orthogonal space sampling temperature. A double-integration recursion method enables practically efficient and robust OST free energy calculations, augmented by a ?-dynamics approach. The double-integration OST method performs alchemical free energy simulations, to calculate the free energy difference between benzyl phosphonate and difluorobenzyl phosphonate in aqueous solution, to estimate the solvation free energy of the octanol molecule, and to predict the nontrivial Barnase-Barstar binding affinity change induced by the Barnase N58A mutation. The DI-OST method robustly enables practically efficient free energy predictions, particularly when strongly coupled slow environmental transitions are involved. A classical set of p38? MAP Kinase inhibitors are also employed as a test bed for evaluating relative binding affinity calculation methods.
Type:
Application
Filed:
December 12, 2013
Publication date:
February 22, 2018
Applicant:
FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
Abstract: This describes homogeneous catalysts that are recoverable from solution by being phase selective and through host-guest interactions. An example of a method includes separating a water soluble N-heterocyclic carbene homogeneous catalyst from a solution by: (a) forming a host-guest compound between the catalyst and an inclusion compound in the solution; and (b) isolating the host-guest compound from the solution.
Type:
Application
Filed:
August 22, 2017
Publication date:
February 22, 2018
Applicant:
Florida State University Research Foundation, Inc.
Abstract: Provided herein is a thermoplastic elastomer hydrogel and methods of making such. The hydrogel comprises a glass formed from poly(styrene)-b-poly(ethylene oxide) in which the coronal chain end has been functionalized with photodimerizable groups (AB-photo) and a liquid medium at a concentration between about 32:1 and about 2:1 liquid medium/AB-photo by weight. The hydrogel has a fatigue resistance to at least 500,000 compression cycles.
Type:
Application
Filed:
June 2, 2017
Publication date:
February 22, 2018
Applicant:
Colorado State University Research Foundation
Inventors:
Travis S. Bailey, Nabila Asem Huq, Vincent F. Scalfani, John R. Ekblad, Alexander T. Leonard
Abstract: Multidentate metal complexes useful as phosphorescent emitters in display and lighting applications have the structures as described herein. Multidentate metal complexes and compositions including one or more of the complexes described herein can be useful as emitters in organic light emitting diodes (OLEDs), displays and lighting applications, and photovoltaic devices. Generally, a chemical structural change will affect the electronic structure of the compounds, which thereby affects the optical properties of the compounds (e.g., emission and absorption spectra). Thus, the compounds described herein can be tailored or tuned to a particular emission or absorption energy. In some aspects, the optical properties of the compounds disclosed herein can be tuned by varying the structure of the ligand surrounding the metal center.
Type:
Grant
Filed:
August 21, 2014
Date of Patent:
February 20, 2018
Assignees:
Arizona Board of Regents on behalf of Arizona State University, Universal Display Corporation
Abstract: The invention relates to the development of chimeric OspA molecules for use in a new Lyme vaccine. More specifically, the chimeric OspA molecules comprise the proximal portion from one OspA serotype, together with the distal portion from another OspA serotype, while retaining antigenic properties of both of the parent polypeptides. The chimeric OspA molecules are delivered alone or in combination to provide protection against a variety of Borrelia genospecies. The invention also provides methods for administering the chimeric OspA molecules to a subject in the prevention and treatment of Lyme disease or borreliosis.
Type:
Grant
Filed:
February 22, 2016
Date of Patent:
February 20, 2018
Assignees:
Research Foundation of the State University of New York, Brookhaven Science Associates, LLC
Inventors:
Brian A. Crowe, Ian Livey, Maria O'Rourke, Michael Schwendinger, John J. Dunn, Benjamin J. Luft
Abstract: To address the inefficiency and unfairness issues in channel bonding, a dynamic channel bonding protocol is presented in which a node is allowed to start a transmission as long as a narrow channel is available and gradually increase channel width during transmission whenever a new narrow channel becomes available. The protocol aggregates all available narrow channels as one wide channel, removing the need of setting guard bands between contiguous narrow channels. A challenge in dynamic channel bonding is the communication over uncertain channels. To enable fast spectrum agreement between transmitter and receiver, a partial spectrum correlation method is introduced. When new channels become available, multiple nodes may contend for them. A compound preamble is designed to make collisions detectable in the frequency domain and a parallel bitwise arbitration mechanism is used to quickly resolve the collisions in the time domain.
Type:
Grant
Filed:
July 9, 2014
Date of Patent:
February 20, 2018
Assignee:
Board Of Trustees Of Michigan State University
Abstract: The present disclosure relates to biosensing systems and biosensing elements having increased storage capability and increased functional lifetimes through using compositions and methods for recycling cofactors.
Type:
Grant
Filed:
October 6, 2015
Date of Patent:
February 20, 2018
Assignee:
Colorado State University Research Foundation
Abstract: A method for probing a target sequence of messenger ribonucleic acid molecules (mRNA's) in a fixed, permeabilized cell, said target sequence including at least 30 non-overlapping probe binding regions of 15-100 nucleotides, comprising immersing said cell in an excess of at least 30 nucleic acid hybridization probes, each singly labeled with the same fluorescent label and each containing a nucleic acid sequence that is complementary to a different probe binding region of said target sequence; washing said fixed cell to remove unbound probes; and detecting fluorescence from said probes.
Type:
Grant
Filed:
September 10, 2009
Date of Patent:
February 20, 2018
Assignee:
Rutgers, The State University of New Jersey
Abstract: A dialysis system includes a filtration system capable of filtering a water stream, a water purification system capable of purifying said water stream in a non-batch process, a mixing system capable of producing a stream of dialysate from mixing one or more dialysate components with the water stream in a non-batch process, and a dialyzer system. The dialyzer may be a microfluidic dialyzer capable of being fluidly coupled to the stream of dialysate and a blood stream.
Type:
Grant
Filed:
June 19, 2014
Date of Patent:
February 20, 2018
Assignees:
Oregon State University, Outset Medical, Inc.
Inventors:
Julie S. Wrazel, James R. Curtis, Ladislaus Nonn, Richard B. Peterson, Hailei Wang, Robbie Ingram-Goble, Luke W. Fisher, Anna E. Garrison, M. Kevin Drost, Goran Jovanovic, Richard Todd Miller, Bruce W. Johnson, Alana Anderson, Eric K. Anderson
Abstract: Materials and methods for treating and preventing an infection or disease, and for directly killing microorganisms, using carboxy-terminal C5a analogs, are provided.
Type:
Grant
Filed:
June 29, 2011
Date of Patent:
February 20, 2018
Assignees:
SAN DIEGO STATE UNIVERSITY RESEARCH FOUNDATION, BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
Inventors:
Sam D. Sanderson, Joy Arlene Phillips, Edward Leroy Morgan, Marilyn Louise Thoman, Tamsin Sheen, Kelly S. Doran, Elizabeth Louise Virts, Tammy Kielian, Mark Hanke
Abstract: Provided is a method for inhibiting the growth of tumor cells comprising administering to an individual in need of treatment, a composition comprising a therapeutically effective amount of Lappaol F. Also provided are compositions comprising Lappaol F and a pharmaceutically acceptable carrier.
Type:
Grant
Filed:
May 6, 2014
Date of Patent:
February 20, 2018
Assignees:
The Research Foundation for the State University of New York, Guangzhou University of Chinese Medicine
Abstract: Implementation of high performance controllable damping devices can ameliorate cost-effectiveness of structural systems for mitigation of natural hazards relative to structures such as building, wind turbines, and off-shore structures. However, the applications of these damping systems are limited due to a lack of 1) mechanical robustness; 2) electrical reliability; and 3) large resisting force capability. To broaden the implementation of modern damping systems, a semi-active damping device is proposed. The device, in one form termed Banded Rotary Friction Device (BRFD), has enhanced applicability compared to other proposed damping systems due to its cost-effectiveness, high damping performance, mechanical robustness, and technological simplicity. Its mechanical principle is based on a band brake, which results in a high amplification of the input force while enabling a variable control force.
Type:
Grant
Filed:
November 9, 2015
Date of Patent:
February 20, 2018
Assignee:
Iowa State University Research Foundation, Inc.
Inventors:
Austin Downey, Simon Laflamme, Douglas P. Taylor
Abstract: The present invention presents methods to alter the genetic composition of crop plants susceptible to nematode infection to improve tolerance to the same. Methods and compositions for modulating key pathways involved in the syncytial event of nematode infection and for preventing the cascade of differential gene expression caused by the same as disclosed. Applicants have found that the microRNA miR396 acts as a master switch of syncytial gene expression changes in plants after infection, and further that miR396 and certain growth regulating transcription factors (GRF) are connected through feedback interaction in syncytium initiation and maintenance.
Type:
Grant
Filed:
July 8, 2015
Date of Patent:
February 20, 2018
Assignee:
Iowa State University Research Foundation, Inc.
Abstract: A method for forming a graphene-reinforced polymer matrix composite is disclosed. The method includes distributing graphite microparticles into a molten thermoplastic polymer phase; and applying a succession of shear strain events to the molten polymer phase so that the molten polymer phase exfoliates the graphite successively with each event until at least 50% of the graphite is exfoliated to form a distribution in the molten polymer phase of single- and multi-layer graphene nanoparticles less than 50 nanometers thick along the c-axis direction.
Type:
Grant
Filed:
March 14, 2013
Date of Patent:
February 20, 2018
Assignee:
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
Inventors:
Thomas Nosker, Jennifer Lynch, Justin Hendrix, Bernard Kear, Gordon Chiu, Stephen Tse
Abstract: Provided herein are metal halide perovskites that may have a 0D crystal structure, and may be lead free. Also provided are methods for making the metal halide perovskites, including methods for making bulk crystals or micro crystals. Devices, such as optoelectronic devices, also are provided that include one or more of the metal halide perovskites. A metal halide perovskite may be a light emitting material in the devices.
Type:
Grant
Filed:
September 20, 2016
Date of Patent:
February 20, 2018
Assignee:
Florida State University Research Foundation, Inc.
Abstract: A radiography apparatus includes a radiation source, a radiation detector, and processing circuitry. The processing circuitry is configured to obtain an X-ray image of an object, obtain a focal spot size of a radiation source used to generate the obtained X-ray image, and estimate a magnification of the obtained X-ray image. The processing circuitry is also configured to obtain, using a look-up table and the obtained focal spot size, a deconvolution kernel. The processing circuitry is also configured to generate a corrected X-ray image by performing a deconvolution operation on the obtained X-ray image using the obtained deconvolution kernel and the estimated magnification.
Type:
Application
Filed:
August 15, 2016
Publication date:
February 15, 2018
Applicants:
The Research Foundation for the State University of New York, Toshiba Medical Systems Corporation
Inventors:
Stephen RUDIN, Daniel R. BEDNAREK, Amit JAIN, Joseph MANAK