Patents Assigned to State University
  • RECOMBINANT BACTERIUM FOR INDUCTION OF CELLULAR IMMUNE RESPONSE
    Publication number: 20150056232
    Abstract: The present invention provides a recombinant bacterium and methods of using the recombinant bacterium to induce a cellular immune response.
    Type: Application
    Filed: March 14, 2013
    Publication date: February 26, 2015
    Applicant: The Arizona Board of Regents for and on behalf of Arizona State University
    Inventor: Roy Curtiss, III
  • Methods of extracting chemical compounds from organisms with resistant cell walls
    Patent number: 8962812
    Abstract: A method is provided for extraction of chemical compounds from an organism having a cell wall that includes adding nanomaterials, which may be metallic nanofibers such as silver nanofibers, to the organism.
    Type: Grant
    Filed: October 19, 2012
    Date of Patent: February 24, 2015
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Maria Teresa Gutierrez-Wing, Kelly Ann Rusch
  • Fibroblast growth factor mutants having improved functional half-life and methods of their use
    Patent number: 8962557
    Abstract: Mutant fibroblast growth factor (FGF) proteins having a polypeptide sequence with a high sequence identity to proteins encoded by members of the Fgf-1 subfamily of genes from a mammalian species, such as human, and with a specific amino acid substitution of an alanine at a position corresponding to amino acid position 66 of human FGF-1 with a cysteine and/or a specific amino acid substitution of a phenylalanine at a position corresponding to amino acid position 132 of human FGF-1 with a tryptophan (based on the 140 amino acid numbering scheme of human FGF-1) are provided. Other amino acid mutations or substitutions may be combined. Polynucleotide sequences encoding the mutant FGF proteins and host cells containing such polynucleotide sequences are provided. Methods of administering a mutant FGF protein to an individual to treat an ischemic condition or disease or a wound or tissue injury are also provided.
    Type: Grant
    Filed: November 6, 2012
    Date of Patent: February 24, 2015
    Assignee: Florida State University Research Foundation
    Inventors: Michael Blaber, Jihun Lee
  • Electro-optical device and method for controlling color with polymer stabilized liquid crystal
    Patent number: 8964161
    Abstract: The present invention provides an electro-optical device comprising a cell of polymer-stabilized blue phase (PSBP) liquid crystal under an electrical field and a method of controlling the reflection and transmission of an incident electromagnetic radiation such as visible light, by way of controlling the electrical field. The invention exhibits merits such as cost-effectiveness; simpler manufacturability due to the removal of requirements of polarizer and color filter; and fast switching, among others.
    Type: Grant
    Filed: June 16, 2010
    Date of Patent: February 24, 2015
    Assignee: Kent State University
    Inventors: Liang-Chy Chien, Shin-Ying Lu
  • Molecular surface design of tyrosine-derived polycarbonates for attachment of biomolecules
    Patent number: 8961948
    Abstract: Methods for constructing tyrosine-derived biotinylated polymers. Biotinylated polymers and polymer scaffolds constructed with the biotinylated polymers are also disclosed.
    Type: Grant
    Filed: January 17, 2012
    Date of Patent: February 24, 2015
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Jared S. Bushman, Jenny E. Raynor, Joachim B. Kohn
  • Private entity authentication for pervasive computing environments
    Patent number: 8966252
    Abstract: A method is provided for authenticating an entity having a plurality of keys in a digital form residing on a claimant computing device. The method comprises: generating a first code word by applying a hash function to a first key residing on the claimant computing device; encoding the first code word into an array of bits having a Bloom filter format; generating a second code word by applying a hash function to a second key residing on the claimant computing device; encoding the second code word into the array of bits; and broadcasting an authentication message having the array of bits therein from the claimant computing device.
    Type: Grant
    Filed: March 12, 2008
    Date of Patent: February 24, 2015
    Assignee: Board of Trustees of Michigan State University
    Inventors: Matt W. Mutka, Feng Zhu, Lionel Ni
  • Device for collection and preservation of tissue or stool samples
    Patent number: 8961429
    Abstract: An arrangement for collecting a tissue or stool sample has a sample vial and a source of preservative fluid. A fluid valve controls a flow of the preservative fluid from the source of preservative fluid to the sample vial. An air equalization vent tube is coupled to the source of preservative fluid and an air valve controls a flow of air through the air equalization vent tube, the air valve and the fluid valve being actuated simultaneously. A scoop for collecting the sample is coupled to the sample vial coupler and extends into the sample vial. The preservative fluid flows from the source of preservative fluid to the sample vial by force of gravity upon actuation of the fluid valve. The air equalization vent tube transfers air from the sample vial to the source of preservative fluid upon actuation of the air valve.
    Type: Grant
    Filed: September 19, 2008
    Date of Patent: February 24, 2015
    Assignee: Wayne State University
    Inventors: Jeffrey L. Ram, Jordan Nechvatal, Ikuko Kato
  • Reagents and methods for cyanobacterial production of bioplastics and biomaterials
    Patent number: 8962300
    Abstract: The present invention provides reagents and methods for biomaterial production from cyanobacteria.
    Type: Grant
    Filed: June 6, 2013
    Date of Patent: February 24, 2015
    Assignee: Arizona Board of Regents, a Body Corporate Acting for and on Behalf of Arizona State University
    Inventors: Hatem Mohammed, Wim Vermaas
  • Thermally stable volatile film precursors
    Patent number: 8962876
    Abstract: A precursor for the deposition of a thin film by atomic layer deposition is provided. The compound has the formula MxLy where M is a metal and L is an amidrazone-derived ligand or an amidate-derived ligand. A process of forming a thin film using the precursors is also provided.
    Type: Grant
    Filed: May 17, 2010
    Date of Patent: February 24, 2015
    Assignee: Wayne State University
    Inventors: Charles H. Winter, Thomas Joseph Knisley, Panditha Koralalage Don Mahesh Chinthaka Karunarathne
  • EGFR-related polypeptides and methods of use
    Patent number: 8962808
    Abstract: Described herein are truncated EGF receptor polypeptides, nucleic acids encoding them, and methods of using them to help select a method of treatment for an EGFR-related cancer, to predict clinical outcome, and to detect micrometastases or minimal residual disease. High EGFR expression and phosphorylated EGFR predicts poor survival in head and neck cancer patients, but does not correlate with advanced stage disease. In our studies, we determined that clinical biological correlates are likely to be more accurate when different aspects of EGFR are evaluated in combination. We analyzed EGFR phosphorylation, expression and mutations in 60 primary head and neck tumors. We not only found that head and neck tumors with either truncated or activated EGFR tend to have higher tumor and nodal stage, but also discovered three EGFR truncations.
    Type: Grant
    Filed: May 5, 2011
    Date of Patent: February 24, 2015
    Assignee: The Research Foundation for the State University of New York
    Inventors: Edward L. Chan, James Keller
  • Artificial compound eye with adaptive microlenses
    Patent number: 8964019
    Abstract: An artificial compound eye formed of three layers of membrane bonded to one another in a stacked relationship. A field chamber is located intermediate the two bottommost membranes. A plurality of focus chambers is located intermediate the two topmost membranes, and an image sensor is located below each focus chamber. The field chamber and each focus chamber contain a pressurized fluid medium. The ceilings of the focus chambers function as lenses though which light must pass to reach the sensors. The fluid pressure in the field chamber can be varied to expand or contract the eye between a planer and a domed configuration, thereby allowing the field of view of the eye to be varied. The fluid pressure in each focus chamber can be varied to expand or contract each lens between a planar and a domed configuration for independently varying the focal length of each lens.
    Type: Grant
    Filed: December 23, 2011
    Date of Patent: February 24, 2015
    Assignee: The Ohio State University
    Inventors: Yi Zhao, Hansong Zeng
  • Fast parallel test of SRAM arrays
    Patent number: 8966329
    Abstract: In general, each parallel test operation on Static Random Access Memory (SRAM) cells is a test operation performed on a block of the SRAM cells in parallel, or simultaneously. In one embodiment, the SRAM cells are arranged into multiple rows and multiple columns where the columns are further arranged into one or more column groups. The block of the SRAM cells for each parallel test operation includes SRAM cells in two or more of the rows, SRAM cells in two or more columns in the same column group, or both SRAM cells in two or more rows and SRAM cells in two or more columns in the same column group.
    Type: Grant
    Filed: July 19, 2011
    Date of Patent: February 24, 2015
    Assignee: Arizona Board of Regents for and on behalf of Arizona State University
    Inventors: Lawrence T. Clark, Yu Cao
  • Self-assembly of coatings utilizing surface charge
    Patent number: 8961767
    Abstract: An apparatus and method for measuring the isoelectric pH for materials deposited on or otherwise affixed onto and in contact with an electrode surface, and a method for utilizing the isoelectric pH to form nanometer thickness, self-assembled layers on the material, are described. Forming such layers utilizing information obtained about the isoelectric pH values of the substrate and the coating is advantageous since the growth of the coating is self-limiting because once the surface charge has been neutralized there is no longer a driving force for the solid electrolyte coating thickness to increase, and uniform coatings without pinhole defects will be produced because a local driving force for assembly will exist if any bare electrode material is exposed to the solution. The present self-assembly procedure, when combined with electrodeposition, may be used to increase the coating thickness.
    Type: Grant
    Filed: March 28, 2011
    Date of Patent: February 24, 2015
    Assignee: Colorado State University Research Foundation
    Inventors: Amy L. Prieto, Derek C. Johnson, James M. Mosby
  • Self-powered timer apparatus
    Patent number: 8963647
    Abstract: A method is provided for implementing a timer using a floating-gate transistor. The method includes: injecting a charge into a floating-gate transistor at an initial time, where a gate terminal of the floating-gate transistor is comprised of polysilicon encased by an insulating material; creating lattice imperfections at boundary of the polysilicon to cause leakage from the floating-gate transistor; measuring current read out from the floating-gate transistor at a time subsequent to the initial time; and determining an amount of time between the initial time and the subsequent time using the measured current.
    Type: Grant
    Filed: February 20, 2013
    Date of Patent: February 24, 2015
    Assignee: Board of Trustees of Michigan State University
    Inventor: Shantanu Chakrabartty
  • Graft polymers for enhanced intracellular delivery of antisense molecules
    Patent number: 8962757
    Abstract: Innovative graft polymers designed for the efficient delivery of antisense molecules into biological cells and for maintaining the biological activity of these molecules while in serum and other aqueous environments are provided. Such polymers may comprise an anionic graft polymer comprising an anionic polymer backbone with pendant carboxylic acid groups and pendant chains comprising amphipathic or hydrophilic polymers covalently bonded to a portion of said pendant carboxylic acid groups. Antisense molecule delivery vectors comprising such polymers in combination with cationic agents for delivery of antisense molecules are also disclosed.
    Type: Grant
    Filed: November 26, 2008
    Date of Patent: February 24, 2015
    Assignee: Rutgers, The State University of New Jersey
    Inventors: David I. Devore, Charles Roth
  • Nanopore and carbon nanotube based DNA sequencer
    Patent number: 8961757
    Abstract: The present invention provides a device for analyzing the composition of a heteropolymer comprising a carbon nanotube through which the heteropolymer is driven by electrophoresis. The carbon nanotube also serves as one electrode in a reading circuit. One end of the carbon nanotube is held in close proximity to a second electrode, and each end of the carbon nanotube is functionalized with flexibly-tethered chemical-recognition moieties, such that one will bind one site on the emerging polymer, and the second will bind another site in close proximity, generating an electrical signal between the two electrodes when the circuit is completed by the process of chemical recognition.
    Type: Grant
    Filed: March 18, 2009
    Date of Patent: February 24, 2015
    Assignees: Arizona Board of Regents, a body corporate of the State of Arizona Acting for and on behalf of Arizona State University, The Trustees of Columbia University in the City of New York
    Inventors: Colin Nuckolls, Jinyao Tang, Stuart Lindsay, Jin He, Peiming Zhang, Kevin Reinhart
  • Buddleja plant named 'Blue Chip Jr'
    Publication number: 20150052650
    Abstract: Buddleja ‘Blue Chip Jr’ is a new and distinct variety of butterfly bush that has the following unique combination of desirable features that are outstanding in a new variety. 1. ‘Blue Chip Jr’ has low vigor resulting in very dwarf stature. 2. ‘Blue Chip Jr’ is asexually propagated using softwood or semi-hardwood cuttings. 3. ‘Blue Chip Jr’ demonstrates a dense, spreading growth habit. 4. ‘Blue Chip Jr’ is lacking male flower parts (anthers), resulting in male (pollen) sterility. 5. ‘Blue Chip Jr’ produces female structures that are essentially sterile, resulting in lack of seed formation. 6. ‘Blue Chip Jr’ has purple-violet flower color.
    Type: Application
    Filed: March 21, 2014
    Publication date: February 19, 2015
    Applicant: North Carolina State University
    Inventor: Dennis James Werner
  • GLUCOSE TRANSPORTER INHIBITORS
    Publication number: 20150051255
    Abstract: Thiazolidinedione compounds and pharmaceutically acceptable salts thereof are described. The compounds can be used in methods of treating cancer in a subject by administering to the subject a therapeutically effective amount of the compound. The compounds can also be used in methods of inhibiting glucose uptake in a cell by contacting the cell with the compound.
    Type: Application
    Filed: March 28, 2013
    Publication date: February 19, 2015
    Applicant: The Ohio State University Research Foundation
    Inventors: Ching-Shih Chen, Dasheng Wang, Samuel K. Kulp
  • CONTROL OF CELLULOSE BIOSYNTHESIS BY OVEREXPRESSION OF A TRANSCRIPTION FACTOR
    Publication number: 20150052641
    Abstract: The invention relates to the over-expression of a transcription factor selected from the group consisting of MYB46, HAM1, HAM2, MYB112, WRKY11, ERF6, and any combination thereof in a plant, which can modulate and thereby modulating the cellulose content of the plant.
    Type: Application
    Filed: February 26, 2013
    Publication date: February 19, 2015
    Applicant: Board of Trustees of Michigan State University
    Inventors: Kyung-Hwan Han, Jae-Heung Ko, Won-Chan Kim, Joo-Yeol Kim
  • Sweetpotato plant named ‘LA04-175’
    Patent number: PP25308
    Abstract: A new variety of sweetpotato, identified as ‘LA04-175’, is disclosed having disease resistance to both fusarium wilt, Streptomyces soil rot, and southern root-knot nematode; an orange flesh and red skin, and high yield characteristics.
    Type: Grant
    Filed: April 23, 2013
    Date of Patent: February 24, 2015
    Assignee: Board of Supervisors of Louisiana State University and A&M College Through The LSU Ag Center
    Inventors: Don R. Labonte, Arthur Q. Villordon, Tara Parker Smith, Christopher A. Clark