Patents Assigned to State University
  • Patent number: 9770470
    Abstract: A method for isolating and processing bone marrow derived stem cells, including the steps of: (a) collecting a biological sample containing adherent bone marrow stem cells in a receptacle with interior walls coated with a cell-adherent substrate; (b) incubating the bone marrow cells on the adherent substrate so that a layer of adherent bone marrow stem cells adheres to the substrate; (c) washing any non-adherent cells from the substrate; and (d) collecting the bone marrow stem cell layer. Isolation kits and use of bone marrow cells harvested for cell therapies are also described.
    Type: Grant
    Filed: October 8, 2015
    Date of Patent: September 26, 2017
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventor: Hatem Sabaawy
  • Patent number: 9771605
    Abstract: The present invention is related to biosynthetic oil compositions and methods of making thereof. In some embodiments, the invention relates to the use of endogenous enzymes in plants capable of synthesizing oil. In preferred embodiments, said plants are algae. In further embodiments, said algae are from the family Chlamydomonas, Nannochloropsis, Dunaliella, Chiarella and Scenedesmus. In still further embodiments, said endogenous enzymes are diacylglycerol acyltransferases.
    Type: Grant
    Filed: June 22, 2015
    Date of Patent: September 26, 2017
    Assignee: Board of Trustees of Michigan State University
    Inventors: Christoph Benning, Rachel Miller, Eric R. Moellering
  • Patent number: 9770465
    Abstract: Preferred embodiments relate to compositions of inherently radiopaque, biocompatible, bioresorbable polymeric particles and methods of using them for embolizing a body lumen.
    Type: Grant
    Filed: March 5, 2014
    Date of Patent: September 26, 2017
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Don K. Brandom, Eric Schmid, Joan Zeltinger, Durgadas Bolikal, Joachim B. Kohn
  • Publication number: 20170267814
    Abstract: A catalyst is prepared in situ by reaction between an aryl halide and a Ni-ligand complex. The catalyst may be used to promote chain-growth polymerization of halogen-substituted Mg or Zn monomers. Polymers, copolymers, block copolymers, polymer thin films, and surface-confined polymer brushes may be produced using the catalyst.
    Type: Application
    Filed: April 28, 2017
    Publication date: September 21, 2017
    Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Evgueni E. Nesterov, Jinwoo Choi
  • Publication number: 20170268032
    Abstract: A solid supported branched linker assay system, including an alpha compound and a beta compounds reversibly tethered to a solid support; a branched linker coupled to the solid support that tethers the alpha and beta compounds to the solid support; the branched linker having two cleavable linkers that are chemically distinct from one another, wherein a first chemically distinct linker tethers the ? compound to the branched linker and a second chemically distinct linker tethers the ? compound to the branched linker; and at least two means for cleaving the chemically distinct linkers, wherein a first cleavage means is configured to selectively cleave a first chemically distinct linker and a second cleavage means is configured to selectively cleave a second chemically distinct linker.
    Type: Application
    Filed: March 20, 2017
    Publication date: September 21, 2017
    Applicant: Middle Tennessee State University
    Inventors: Kevin L. Bicker, Kevin J. Fisher, Ashley E. Corson
  • Publication number: 20170269001
    Abstract: A biosensing system that measures the concentration of halogenated alkenes is disclosed.
    Type: Application
    Filed: October 1, 2012
    Publication date: September 21, 2017
    Applicant: Colorado State University Research Foundation
    Inventors: Kenneth F. Reardon, Brian C. Heinze
  • Publication number: 20170268158
    Abstract: The present disclosure provides system and method for drying various materials using an air-to-air heat exchanger in sequence with a liquid-to-air heat exchanger to provide heat to a chamber to remove moisture from materials contained within the chamber in an energy efficient manner.
    Type: Application
    Filed: March 15, 2017
    Publication date: September 21, 2017
    Applicant: The Research Foundation for The State University of New York
    Inventor: Jon P. Owejan
  • Publication number: 20170272411
    Abstract: A new efficient framework based on a Constant-size Ciphertext Policy Comparative Attribute-Based Encryption (CCP-CABE) approach. CCP-CABE assists lightweight mobile devices and storing privacy-sensitive sensitive data into cloudbased storage by offloading major cryptography-computation overhead into the cloud without exposing data content to the cloud. CCP-CABE extends existing attribute-based data access control solutions by incorporating comparable attributes to incorporate more flexible security access control policies. CCP-CABE generates constant-size ciphertext regardless of the number of involved attributes, which is suitable for mobile devices considering their limited communication and storage capacities.
    Type: Application
    Filed: June 8, 2017
    Publication date: September 21, 2017
    Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Dijiang HUANG, Zhijie WANG
  • Patent number: 9768107
    Abstract: Some embodiments include a method. The method can include providing a carrier substrate, providing a release layer over the carrier substrate, and providing a device substrate over the carrier substrate and the release layer. Providing the device substrate can include bonding the device substrate to the carrier substrate, and bonding the device substrate to the release layer. Further, providing the release layer can include bonding the release layer to the carrier substrate. Meanwhile, the release layer can include polymethylmethacrylate, and the device substrate can be bonded to the carrier substrate with a first adhesion strength, the device substrate can be bonded to the release layer with a second adhesion strength less than the first adhesion strength, and the release layer can be bonded to the carrier substrate with a third adhesion strength greater than the second adhesion strength. Other embodiments of related methods and devices are also disclosed.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: September 19, 2017
    Assignee: ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Emmett Howard, Nicholas Munizza, Paul Yee
  • Patent number: 9765328
    Abstract: The present invention provides stable, nuclease-resistant TNA and TNA-DNA oligonucleotides, wherein the oligonucleotides are completely resistant to enzymatic degradation for at least 24-72 hours. Methods of synthesis and use in diagnostic and therapeutic applications are also provided. Specifically, in one embodiment, we describe the chemical and biological stability of TNA and mixed-backbone (mosaic) TNA-DNA oligonucleotides under a variety of conditions and sequence contexts.
    Type: Grant
    Filed: November 24, 2015
    Date of Patent: September 19, 2017
    Assignee: Arizona Board of Regents on Behalf of Arizona State University
    Inventor: John Chaput
  • Patent number: 9765196
    Abstract: Inorganic polymers are produced from silicate (—Si—O—) and/or phosphonate (—P—O—) bonds, commonly found in rocks and glass, to create new polymeric materials for rubbers, fibers, and plastics. These inorganic polymers have various advantages over organic counterparts including abundance on the earth's crust, and properties including nonflammability, low toxicity, recyclability, and excellent thermal and chemical resistance.
    Type: Grant
    Filed: February 20, 2015
    Date of Patent: September 19, 2017
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Masanori Hara, Richard Lehman
  • Patent number: 9765115
    Abstract: The chain of events that explains calcitonin receptor (CTR)-stimulated invasion and metastasis of prostate cancer cells was identified. The CTR-stimulated events depend on the interaction of CTR with the PDZ3 domain of ZO-1. Small peptides and small molecules were identified that inhibit this interaction. The small inhibitory peptides were synthesized and can be used to attenuate or inhibit metastasis in solid cancer tumors.
    Type: Grant
    Filed: March 30, 2012
    Date of Patent: September 19, 2017
    Assignee: Board of Supervisors of Louisiana State University acting on behalf of the University of Louisiana at Monroe
    Inventor: Girish V. Shah
  • Patent number: 9767284
    Abstract: Trustworthy systems require that code be validated as genuine. Most systems implement this requirement prior to execution by matching a cryptographic hash of the binary file against a reference hash value, leaving the code vulnerable to run time compromises, such as code injection, return and jump-oriented programming, and illegal linking of the code to compromised library functions. The Run-time Execution Validator (REV) validates, as the program executes, the control flow path and instructions executed along the control flow path. REV uses a signature cache integrated into the processor pipeline to perform live validation of executions, at basic block boundaries, and ensures that changes to the program state are not made by the instructions within a basic block until the control flow path into the basic block and the instructions within the basic block are both validated.
    Type: Grant
    Filed: June 18, 2015
    Date of Patent: September 19, 2017
    Assignee: The Research Foundation for The State University of New York
    Inventor: Kanad Ghose
  • Patent number: 9766239
    Abstract: Synbodies specific for Norovirus and coupled with a substrate provide Norovirus binding and detection platforms (FIG. 1). A Norovirus capturing platform, comprising one or more synbodies selected from the group consisting of synbodies 6-6, 92-92, 93-93, and 94-94 coupled to a substrate, has been found to found to bind with either GII.4 Minerva or both GII.4 Minerva and GII.4 Sydney# strains of norovirus.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: September 19, 2017
    Assignee: Arizona Board of Regents on Behalf of Arizona State University
    Inventors: Nidhi Gupta, Chris Diehnelt, Charles Arntzen, Stephen Johnston
  • Patent number: 9763912
    Abstract: Embodiments of the present disclosure provide for compositions including an antimicrobial agent, pharmaceutical compositions including the composition or pharmaceutical composition, methods of treating a condition or disease, methods of treatment using compositions or pharmaceutical compositions, and the like.
    Type: Grant
    Filed: October 30, 2014
    Date of Patent: September 19, 2017
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Chu Chen, Jian Zhang
  • Patent number: 9768462
    Abstract: A liquid electrolyte formed by reacting phosphoric acid (H3PO4) in the liquid state with silicon tetrachloride (SiCl4), thereby forming a fluid suspension. The fluid suspension is heated to yield a liquid electrolyte including phosphoric acid (H3PO4), pyrophosphoric acid (H4P2O7), and a particulate solid comprising a silicophosphoric acid, wherein the silicophosphoric acid is an acidic molecular compound including silicon and phosphorus. A concentrated silicophosphoric acid composition prepared by removing most of the liquid from the liquid electrolyte is dissolved in water to yield a homogeneous solution. The homogeneous solution is dried to yield a solid electrolyte. In some cases, the homogenous solution is dried on a substrate to coat at least a portion of the substrate with a proton conductive solid electrolyte. A fuel cell may include the liquid electrolyte, the solid electrolyte, or the coated substrate.
    Type: Grant
    Filed: May 4, 2017
    Date of Patent: September 19, 2017
    Assignee: ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: C. Austen Angell, Younes Ansari, Telpriore Greg Tucker
  • Patent number: 9767271
    Abstract: A pipelined processor comprising a cache memory system, fetching instructions for execution from a portion of said cache memory system, an instruction commencing processing before a digital signature of the cache line that contained the instruction is verified against a reference signature of the cache line, the verification being done at the point of decoding, dispatching, or committing execution of the instruction, the reference signature being stored in an encrypted form in the processor's memory, and the key for decrypting the said reference signature being stored in a secure storage location. The instruction processing proceeds when the two signatures exactly match and, where further instruction processing is suspended or processing modified on a mismatch of the two said signatures.
    Type: Grant
    Filed: December 28, 2015
    Date of Patent: September 19, 2017
    Assignee: The Research Foundation for The State University of New York
    Inventor: Kanad Ghose
  • Patent number: 9763968
    Abstract: Formulations of cross-linkable polymers, capable of forming non-toxic and biocompatible hydrogels in situ, containing at least one of doxycycline or minocycline. Methods of using the hydrogels for treating the skin or ocular tissues of mammals exposed to vesicant compounds such as sulfur mustard (SM), nitrogen mustard (NM) or half mustard (2-chloroethyl ethyl sulfide (CEES)) are also disclosed.
    Type: Grant
    Filed: May 31, 2016
    Date of Patent: September 19, 2017
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Patrick J. Sinko, Manjeet Deshmukh, Siva N. Priya Anumolu, Anupa R. Menjoge, Marion K. Gordon
  • Patent number: 9766248
    Abstract: Embodiments disclosed herein are directed to recognition tunneling systems, methods and devices, and more particularly, to chemical reactions for selectively labeling proteins and peptides and placing protein and/or peptides into, or onto a nanopore formed in a solid support and threading such in and/or through the nanopore, with such nanopores, in some embodiments, including a molecular motor to pull or otherwise force the protein/peptide through the nanopore.
    Type: Grant
    Filed: May 23, 2014
    Date of Patent: September 19, 2017
    Assignee: Arizona Board of Regents of behalf of Arizona State University
    Inventors: Stuart Lindsay, Peiming Zhang, Sudipta Biswas
  • Publication number: 20170258962
    Abstract: The present disclosure provides modified bone and osteochondral tissues, methods of preparing modified bone and osteochondral tissues, and methods of using the modified bone or osteochondral tissues to repair bone or osteochondral defects in a subject.
    Type: Application
    Filed: March 8, 2017
    Publication date: September 14, 2017
    Applicants: Colorado State University Research Foundation, The Regents of the University of California
    Inventors: Suzanne M. Tabbaa, David D. Frisbie, C. Wayne McIlwraith, Robert L. Sah, William D. Bugbee