Patents Assigned to State University
  • MicroRNA fingerprints during human megakaryocytopoiesis
    Patent number: 8865885
    Abstract: Described herein is a pharmaceutical composition for treating a subject having a cancer and/or myeloproliferative disorder associated with overexpression of a HOXA1 gene product where an effective amount of at least one miR-10a gene product or an isolated variant or biologically-active fragment thereof is administered to the subject sufficient to decrease expression of the HOXA1 gene product in the subject.
    Type: Grant
    Filed: June 25, 2013
    Date of Patent: October 21, 2014
    Assignee: The Ohio State University Research Foundation
    Inventors: Carlo M. Croce, Ramiro Garzon, George A. Calin
  • Systems and methods for training an active random field for real-time image denoising
    Patent number: 8866936
    Abstract: An Active Random Field is presented, in which a Markov Random Field (MRF) or a Conditional Random Field (CRF) is trained together with a fast inference algorithm using pairs of input and desired output and a benchmark error measure.
    Type: Grant
    Filed: July 23, 2009
    Date of Patent: October 21, 2014
    Assignee: Florida State University of Research Foundation
    Inventor: Adrian Gheorghe Barbu
  • Aminoglycosides: synthesis and use as antifungals
    Patent number: 8865665
    Abstract: The present invention relates to novel aminoglycoside analogs having certain substituents at the 6 position of ring III which exhibit improved antifungal activity but possess minimal antibacterial properties. The compounds of the present invention are analogues of kanamycin A. Also provided are methods of synthesizing and methods of using the compounds of the present invention. The compounds of the present invention are useful in treating or preventing fungal disease.
    Type: Grant
    Filed: December 12, 2011
    Date of Patent: October 21, 2014
    Assignee: Utah State University
    Inventors: Cheng-Wei T. Chang, Jon Takemoto
  • System and method for controlling a file system
    Patent number: 8868626
    Abstract: According to various embodiments of the invention, a system and method for controlling a file system. In some embodiments, a control plane interposes between a data plane user and a data plane, intercepts file system operations, and performs control plane operations upon the file system operations. In one such embodiment, the system and method is implemented between a data plane user that is a local file system user and a data plane that is a local file system. In another such embodiment, the system and method is implemented between a data plane user that is a client and a data plane that is a file server. Furthermore, for an embodiment where the control plane that interposes between a client and a file server, the control plane can be implemented as a file system proxy. Control plane operations include, but are not limited to, observation, verification, and transformation of a file system operation.
    Type: Grant
    Filed: April 14, 2008
    Date of Patent: October 21, 2014
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Liviu Iftode, Stephen Smaldone, Aniruddha Bohra
  • Analyte sensors, methods for preparing and using such sensors, and methods of detecting analyte activity
    Patent number: 8865416
    Abstract: Analyte sensors, methods for producing and using analyte sensors, methods of detecting and/or measuring analyte activity, detecting pH change, and/or, controlling the concentration of an analyte in a system, are disclosed. Embodiments of the analyte sensors according to the disclosure can provide an accurate and convenient method for characterizing analyte activity, detecting pH change, controlling the concentration of an analyte in a system, and the like, in both in vivo and in vitro environments, in particular in living cell imaging.
    Type: Grant
    Filed: October 19, 2011
    Date of Patent: October 21, 2014
    Assignee: Georgia State University Research Foundation, Inc.
    Inventors: Jenny Jie Yang, Shen Tang
  • Methods and apparatus for controlling dispersions of nanoparticles
    Patent number: 8867121
    Abstract: Electrically reconfigurable metamaterial with spatially varied refractive index is proposed for applications such as optical devices and lenses. The apparatus and method comprises a metamaterial in which the refractive indices are modified in space and time by applying one or more electric fields. The metamaterials are electrically controllable and reconfigurable, and consist of metal (gold, silver, etc.) particles of different shapes, such as rods, with dimension much smaller than the wavelength of light, dispersed in a dielectric medium. The metamaterial is controlled by applying a non-uniform electric field that causes two effects: (1) It aligns the metallic anisometric particles with respect to the direction of the applied electric field and (2) It redistributes particles in space, making their local concentration position dependent.
    Type: Grant
    Filed: October 13, 2009
    Date of Patent: October 21, 2014
    Assignee: Kent State University
    Inventors: Oleg D. Lavrentovich, Andrii B. Golovin
  • Method of Forming Non-Immunogenic Hydrophobic Protein Nanoparticles, and Uses Therefor
    Publication number: 20140308351
    Abstract: Methods are described for producing non-immunogenic nanoparticles from protein sources by controlling the pH in a nanoprecipitation process. The nanoparticles that are produced by the disclosed methods range in diameter size from about 100 ran to about 400 nm, with a preferred diameter size of from approximately 100 nm to approximately 300 nm, thereby rendering them non-immunogenic. The invention further discloses methods for producing nanoconjugates that are suitable for a variety of therapeutic, diagnostic and other uses.
    Type: Application
    Filed: March 10, 2014
    Publication date: October 16, 2014
    Applicant: South Dakota State University
    Inventors: Omathanu P. Perumal, Satheesh K. Podaralla, Radhey S Kaushik
  • REACTION-BASED FLUORESCENT PROBES FOR SULFANE SULFUR AND THE APPLICATION IN BIOIMAGING
    Publication number: 20140308696
    Abstract: Reaction-based fluorscent probes are provided which detect, for example, biologically important sulfane sulfur species (persulfide, polysulfide, and elemental sulfur) in, for example, complex and living systems. The probes are high in selectivity and sensitivity to sulfane sulfurs. Moreover, probes are suitable for bioimaging sulfane sulfurs in living cells.
    Type: Application
    Filed: April 11, 2014
    Publication date: October 16, 2014
    Applicant: Washington State University
    Inventors: Ming Xian, Wei Chen
  • SYSTEMS AND METHODS FOR CAPTURE AND SEQUESTRATION OF GASES AND COMPOSITIONS DERIVED THEREFROM
    Publication number: 20140308507
    Abstract: A composition is produced by a hydrothermal liquid phase sintering process, and the process includes providing a porous matrix, the porous matrix having a shape, and allowing a component of the porous matrix to undergo a reaction with an infiltrating medium to form a first product, the infiltrating medium including a greenhouse gas, a remainder of the porous matrix acting as a scaffold for facilitating the formation of the first product. The composition includes the first product and the reminder of the porous matrix. The composition has a microstructure that resembles a net-like interconnecting network. The composition maintains the shape of the porous matrix. The composition is free of hydraulic bonds.
    Type: Application
    Filed: May 12, 2014
    Publication date: October 16, 2014
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Richard E. RIMAN, Vahit ATAKAN
  • Graduation Mortarboard Display Holder
    Publication number: 20140305014
    Abstract: A mortar board display holder comprises a board clip portion, a display supporter portion, and a connecting portion joining the board clip portion and the display supporter portion. The board clip portion has a flat upper prong having a first plane, a flat lower prong having a second plane, and a spacing member that holds the upper prong fixably spaced from the lower prong such that the second plane is substantially parallel to the first plane. The display supporter portion has a flat first leg having a third plane, a flat second leg having a fourth plane, and a holding member that holds the first leg and the second leg such that the third plane is substantially parallel to the fourth plane. The display supporter portion may further comprise a neck adjacent to and connected to the holding member, and an elongated arm adjacent to and connected to the neck. The neck may be straight or curved.
    Type: Application
    Filed: April 12, 2013
    Publication date: October 16, 2014
    Applicant: California State University Fresno
    Inventors: Ramakrishna Nunna, Walter Mizuno
  • Inhibitors of influenza endonuclease activity and tools for their discovery
    Patent number: 8859290
    Abstract: The invention provides inhibitors of influenza endonuclease activity and tools for their discovery.
    Type: Grant
    Filed: July 20, 2012
    Date of Patent: October 14, 2014
    Assignee: Rutgers, the State University of New Jersey
    Inventors: Joseph D. Bauman, Kalyan Das, Disha Patel, Eddy Arnold
  • Integrated circuits secure from invasion and methods of manufacturing the same
    Patent number: 8860197
    Abstract: An integrated circuit device that is secure from invasion and related methods are disclosed herein. Other embodiments are also disclosed herein.
    Type: Grant
    Filed: December 29, 2009
    Date of Patent: October 14, 2014
    Assignee: Arizona Board of Regents, a Body Corporate of the State of Arizona Acting for and on Behalf of Arizona State University
    Inventors: Lawrence T. Clark, David R. Allee
  • Isolated soft-switch single-stage AC-DC converter
    Patent number: 8861238
    Abstract: An alternating current-to-direct current (AC-DC) converter is provided. The converter may include a transformer having a primary side and a secondary side. A first bi-directional switch and a first inductor may be connected in series between a positive terminal of an AC source and a first terminal of the primary side of the transformer. A second bi-directional switch and a second inductor may be connected between the positive terminal of the AC source and a second terminal of the primary side of the transformer and connected in parallel with the first bi-directional switch.
    Type: Grant
    Filed: August 27, 2012
    Date of Patent: October 14, 2014
    Assignee: North Carolina State University
    Inventors: Qin Huang, Yu Du, Wenxi Yao
  • Methods and devices for modulating cellular activity using ultrasound
    Patent number: 8858440
    Abstract: The present invention comprises methods and devices for modulating the activity or activities of living cells, such as cells found in or derived from humans, animals, plants, insects, microorganisms and other organisms. Methods of the present invention comprise use of the application of ultrasound, such as low intensity, low frequency ultrasound, to living cells to affect the cells and modulate the cells' activities. Devices of the present invention comprise one or more components for generating ultrasound waves, such as ultrasonic emitters, transducers or piezoelectric transducers, composite transducers, CMUTs, and which may be provided as single or multiple transducers or in an array configurations. The ultrasound waves may be of any shape, and may be focused or unfocused.
    Type: Grant
    Filed: September 12, 2013
    Date of Patent: October 14, 2014
    Assignee: Arizona Board of Regents for and on Behalf of Arizona State University
    Inventor: William James P. Tyler
  • Brush with structure for hair removal
    Patent number: 8857005
    Abstract: A hair brush that permits quick and easy removal of hair has a handle attached to a head. The head is made up of at least two frames that are mounted to the handle through cantilevers that permit movement of the frames relative to one another. The bristles are mounted to the frames, preferably in single rows. A force applied to one frame moves that frame relative to the other frame and the handle, thereby permitting the user to reach between the frames to remove any hair that is caught in the bristles. The brush allows a gap between the bristles to be enlarged, thereby making removal using human fingers much easier. Repeated movement and return of the frames to their resting position can cause the hair fibers to work away from the bristle bases and make removal much easier.
    Type: Grant
    Filed: February 9, 2012
    Date of Patent: October 14, 2014
    Assignee: The Ohio State University
    Inventors: Scott Shim, Wonmo Koo
  • Flexible identification systems and related methods
    Patent number: 8860575
    Abstract: Embodiments of flexible identification systems are described herein. Other embodiments and related methods are also disclosed herein.
    Type: Grant
    Filed: November 29, 2011
    Date of Patent: October 14, 2014
    Assignee: Arizona Board of Regents, a body corporate of the State of Arizona, Acting for and on behalf of Arizona, State University
    Inventors: David R. Allee, Lawrence T. Clark, Terry L. Alford, Constantine A. Balanis, James T. Aberle, Kevin Baugh
  • Breast cancer biomarker signatures for invasiveness and prognosis
    Patent number: 8859202
    Abstract: MicroRNA profiles transition from normal breast to ductal carcinoma in situ and transition to invasive ductal carcinoma (IDC) and methods of use thereof are described. Methods of diagnosis and prognosis using microRNA signatures to differentiate invasive from in situ carcinoma are described. Also described is the use of microRNA expression for predicting overall survival and time to metastasis.
    Type: Grant
    Filed: January 22, 2013
    Date of Patent: October 14, 2014
    Assignee: The Ohio State University
    Inventors: Carlo M. Croce, Stefano Volinia
  • Isothiocyanate compounds, pharmaceutical compositions, and uses thereof
    Patent number: 8859798
    Abstract: Provided herein are compositions of matter and pharmaceutical compositions thereof, for use in inhibiting the growth of various microbial pathogens, including bacteria, fungi, protozoa, and viral pathogens. Also provided herein are methods of treating microbial diseases/infections and cancer with the compositions. The compositions are additionally useful in wood preservation and food preservation by inhibition of microbial growth.
    Type: Grant
    Filed: July 6, 2007
    Date of Patent: October 14, 2014
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Arkady Mustaev, Natalia Kurepina
  • Negative stiffness device and method
    Patent number: 8857110
    Abstract: A negative stiffness device and method for seismic protection of a structure is described. In one embodiment, the device has an anchor frame and a movement frame laterally translatable relative to the anchor frame. The anchor frame and movement frame have respective extension portions. A linkage is pivotably connected to the extension portion of the anchor frame. A compressed spring has a first end is attached to the extension portion of the movement frame and a second end attached to the linkage. The compressed spring has a spring force. In a rest state, the compressed spring does not apply a lateral force to the movement frame. In an engaged state, the compressed spring is configured to apply a lateral force to displace the movement frame in a lateral direction of a seismic load. The spring force is amplified by the linkage when the movement frame is laterally displaced to an amplification point.
    Type: Grant
    Filed: November 9, 2012
    Date of Patent: October 14, 2014
    Assignees: The Research Foundation for The State University of New York, William Marsh Rice University, Taylor Devices, Inc.
    Inventors: Michael C. Constantinou, Andrei M. Reinhorn, Apostolos A. Sarlis, Douglas Taylor, David A. Lee, Satish Nagarajaiah, Dharma Theja R. Pasala
  • Crapemyrtle plant named ‘CREC-0077’
    Patent number: PP24978
    Abstract: A new and distinct cultivar of Lagerstroemia crapemyrtle plant named ‘CREC-0077’, characterized by its clear red color flowers and medium to large growth habit.
    Type: Grant
    Filed: September 27, 2012
    Date of Patent: October 21, 2014
    Assignee: Mississippi State University
    Inventors: Patricia R. Knight, Wayne J. McLaurin