Patents Assigned to State University
  • Mini-cell, on-orbit, temperature re-calibration apparatus and method
    Patent number: 8657487
    Abstract: A method for on-orbit calibration of the temperature sensors of a simulated blackbody is disclosed. The method may include selecting a simulated blackbody traveling in a micro-gravity environment and comprising a sensor, a container positioned proximate the senor and containing a material, and a heat transfer device positioned proximate the at least one container. The heat transfer device may transition the material through a phase change. The temperature sensor may monitor the temperature of the material during the phase change. A correction may be calculated to correct any disparity between the temperature reported by the temperature sensor during the phase change and the known plateau temperature corresponding to that phase change. The correction may be applied to subsequent temperature readings obtained using the temperature sensor.
    Type: Grant
    Filed: June 11, 2009
    Date of Patent: February 25, 2014
    Assignee: Utah State University Research Foundation
    Inventors: Gail Bingham, Troy Shane Topham, Alan Thurgood
  • Downdraft gasifier with internal cyclonic combustion chamber
    Patent number: 8657892
    Abstract: A downdraft gasifier is disclosed. The gasifier includes a biomass section that accepts and stirs raw biomass materials, a pyrolysis and tar cracking section having an inner cylinder for receiving biomass and an outer surrounding cylinder for gases from the biomass, and a char gasification section for receiving biomass and gases from the pyrolysis and tar cracking section. The char gasification section provides a grating and scraper for passing gases and ash and retaining biomass for char gasification on the grate.
    Type: Grant
    Filed: June 29, 2009
    Date of Patent: February 25, 2014
    Assignee: The Board of Regents for Oklahoma State University
    Inventors: Krushna N. Patil, Raymond L. Huhnke, Danielle D. Bellmer
  • Integrin-linked kinase inhibitors
    Patent number: 8658647
    Abstract: A number of compounds and use of the compounds in a method for treating or preventing cancer in a subject by administering to the subject a pharmaceutical composition including a compound of formula I or a pharmaceutically acceptable salt thereof are described. The compounds can also be used to inhibit integrin-linked kinase in a cell, which has an effect on the Akt signaling pathway.
    Type: Grant
    Filed: November 21, 2011
    Date of Patent: February 25, 2014
    Assignee: The Ohio State University Research Foundation
    Inventors: Ching-Shih Chen, Su-Lin Lee, Samuel K. Kulp
  • Methods for diagnosing colon cancer using MicroRNAs
    Patent number: 8658362
    Abstract: The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provides methods of identifying inhibitors of tumorigenesis.
    Type: Grant
    Filed: February 28, 2012
    Date of Patent: February 25, 2014
    Assignee: The Ohio State University
    Inventors: Carlo M. Croce, George A. Calin, Stefano Volinia
  • Process for the synthesis of methacrylate-derivatized type-1 collagen and derivatives thereof
    Patent number: 8658711
    Abstract: Methods for synthesizing a methacrylate-derivatized type-I collagen in which methacrylic acid is reacted with a carboxylic acid activating reagent in the presence of a carbodiimide to form a methacrylic acid with an activated carboxylic acid group, which is then reacted with free amino groups on type-I collagen to form a collagen methacrylamide. Methacrylate-derivatized collagen, cross-linked collagens formed therefrom and products containing the cross-linked collagen are also disclosed.
    Type: Grant
    Filed: September 29, 2011
    Date of Patent: February 25, 2014
    Assignee: Rutgers, The State University of New Jersey
    Inventors: David Shreiber, Ian Gaudet
  • Development of a high strength high toughness steel
    Patent number: 8657972
    Abstract: A bainitic steel with simultaneous high yield strength and high fracture toughness includes at least 5 volume percent austenite as well as iron, carbon, and silicon. The silicon is present in an amount of at least 1.5 weight percent of total weight of the bainitic steel. A method of forming the steel by austempering is also provided.
    Type: Grant
    Filed: December 24, 2008
    Date of Patent: February 25, 2014
    Assignee: Wayne State University
    Inventor: Susil K. Putatunda
  • Modified chloroquines with single ring moiety or fused ring moiety
    Patent number: 8658648
    Abstract: The disclosure provides modified chloroquine compounds having single ring or fused ring moieties. Also provided are pharmaceutical compositions comprising such compounds, methods of using such compounds to inhibit or treat diseases or conditions caused by chloroquine-resistant (CQR) and chloroquine-sensitive (CqS) malaria parasites and other CQ-susceptible microorganisms, and processes and intermediates useful for preparing such compounds.
    Type: Grant
    Filed: December 4, 2009
    Date of Patent: February 25, 2014
    Assignees: DesignMedix, Inc., Portland State University
    Inventors: David H. Peyton, Steven J. Burgess, Katherine M. Liebman, Bornface Gunsaru
  • Effect of natural and synthetic antioxidants on the oxidative stability of biodiesel
    Patent number: 8657890
    Abstract: Disclosed are biodiesel fuels with improved oxidative stability. Disclosed are biodiesel fuels which comprise two or more antioxidants which increase the oxidative stability of the biodiesel fuel.
    Type: Grant
    Filed: February 26, 2009
    Date of Patent: February 25, 2014
    Assignee: Wayne State University
    Inventors: K.Y. Simon Ng, Haiying Tang, Steven O. Salley
  • Depth-optimal mapping of logic chains in reconfigurable fabrics
    Patent number: 8661394
    Abstract: A method of creating logic chains in a Boolean network of a reconfigurable fabric is provided. The method includes creating a plurality of logic chains in the reconfigurable fabric. The plurality of logic chains include at least one arithmetic logic chain and at least one non-arithmetic logic chain. A method of creating logic chains in a Boolean network of a look-up table based FPGA includes: applying a labeling method by (a) finding a depth increasing node, (b) isolating the depth increasing node, and (c) finding minimum height cuts; mapping to generate a mapping solution using the minimum height cuts; applying a duplication method to implement an exclusivity constraint; and arranging connections in the look-up table based FPGA using the logic chains.
    Type: Grant
    Filed: September 24, 2008
    Date of Patent: February 25, 2014
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Michael T. Frederick, Arun K. Somani
  • MicroRNA-based methods and compositions for the diagnosis, prognosis and treatment of breast cancer
    Patent number: 8658370
    Abstract: The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of breast cancer. The invention also provides methods of identifying anti-breast cancer agents.
    Type: Grant
    Filed: January 31, 2008
    Date of Patent: February 25, 2014
    Assignee: The Ohio State University Research Foundation
    Inventors: Carlo M. Croce, George A. Calin
  • Variable frequency patch antenna
    Patent number: 8659498
    Abstract: A patch antenna system comprises a patch antenna having a patch spatially separated from a ground plane; a plurality of pins interposed between the patch and the ground plane selectively connecting the patch to the ground plane; and a control module operably coupled to the plurality of pins and operable to set an operating frequency characteristic of the patch antenna by selectively connecting the patch to the ground plane with one or more of the plurality of pins.
    Type: Grant
    Filed: April 15, 2010
    Date of Patent: February 25, 2014
    Assignee: Board of Trustees Operating Michigan State University
    Inventors: Edward J. Rothwell, Lynn Greetis
  • POLYESTERS AND METHODS OF USE THEREOF
    Publication number: 20140050692
    Abstract: The invention provides polymers and methods for the treatment of pain and inflammation.
    Type: Application
    Filed: August 19, 2013
    Publication date: February 20, 2014
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Kathryn E. Uhrich, Roselin Rosario-Melendez
  • Hepatocyte Growth Factor Mimics as Therapeutic Agents
    Publication number: 20140051633
    Abstract: Small molecule, peptidic hepatocyte growth factors mimics, which act as both mimetics and antagonists, have been generated. These molecules have been shown or predicted to have therapeutic potential for numerous pathologies including dementia (e.g. Alzheimer's) and Parkinson's disease.
    Type: Application
    Filed: September 27, 2013
    Publication date: February 20, 2014
    Applicant: Washington State University
    Inventors: Joseph W. Harding, John W. Wright, Caroline C. Benoist, Leen H. Kawas, Gary A. Wayman
  • Inhibition of bacterial biofilms with imidazole derivatives
    Patent number: 8653124
    Abstract: Disclosure is provided for imidazole derivative compounds that prevent, remove and/or inhibit the formation of biofilms, compositions comprising these compounds, devices comprising these compounds, and methods of using the same.
    Type: Grant
    Filed: February 2, 2011
    Date of Patent: February 18, 2014
    Assignee: North Carolina State University
    Inventors: Christian Melander, John Cavanagh, Robert W. Huigens, III, T. Eric Ballard, Justin J. Richards
  • Aminated materials for assays
    Patent number: 8652564
    Abstract: Protein binding onto a polymeric surface is enhanced by treating the surface with an amine-bearing polymer like poly(ethylene imine). When used in ELISA, the treated surface improves the performance of the assay.
    Type: Grant
    Filed: May 7, 2007
    Date of Patent: February 18, 2014
    Assignee: The Ohio State University Research Foundation
    Inventors: Shang-Tian Yang, Yunling Bai
  • Semantic translation of time-driven simulink diagrams using input/output extended finite automata
    Patent number: 8655636
    Abstract: A method of semantic translation of a class of diagrams to input/output-extended finite automata is provided. The method includes receiving a data representation of a diagram, said diagram comprising a plurality of blocks and said diagram being associated with a graphical modeling environment which defines semantics for executing the diagram, and processing, using a computing device, the data representation of the diagram to translate the diagram to an input/output-extended finite automata model.
    Type: Grant
    Filed: June 22, 2011
    Date of Patent: February 18, 2014
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Ratnesh Kumar, Changyan Zhou
  • Dual beneficial effect of dopamine enhancing and neuroprotective actions of PKC delta inhibitors for treatment of Parkinson's disease
    Patent number: 8653023
    Abstract: The present invention describes novel pharmaceutical compositions and methods for treatment of diseases, disorders, or conditions characterized by dopamine deficiency, including Alzheimer's disease, Parkinson's disease, Tourette's syndrome, schizophrenia, Huntington's disease, symptoms of attention deficit hyperactivity disorder, drug abuse and clinical depression. The treatment of the present invention utilizes PKCd inhibitors that have the dual benefit of increasing the levels of dopamine in the central nervous system while also protecting neuronal cells from neurodegeneration.
    Type: Grant
    Filed: June 30, 2006
    Date of Patent: February 18, 2014
    Assignee: Iowa State University Research Foundation, Inc.
    Inventor: Anumantha G. Kanthasamy
  • Probabilistic decision making system and methods of use
    Patent number: 8655822
    Abstract: Embodiments of this invention comprise modeling a subject's state and the influence of training scenarios, or actions, on that state to create a training policy. Both state and effects of actions are modeled as probabilistic using Partially Observable Markov Decision Process (POMDP) techniques. The POMDP is well suited to decision-theoretic planning under uncertainty. Utilizing this model and the resulting training policy with real world subjects creates a surprisingly effective decision aid for instructors to improve learning relative to a traditional scenario selection strategy. POMDP provides a more valid representation of trainee state and training effects, thus it is capable of producing more valid recommendations concerning how to structure training to subjects.
    Type: Grant
    Filed: March 11, 2009
    Date of Patent: February 18, 2014
    Assignees: Aptima, Inc., Wright State University
    Inventors: Georgiy Levchuk, Jared Freeman, Wayne Shebilske
  • System, apparatus, and method for simultaneous single molecule atomic force microscopy and fluorescence measurements
    Patent number: 8656510
    Abstract: An apparatus, system, and method of integrating atomic force microscopy (AFM) and fluorescence microscopy (FM). One particular application is to simultaneous single molecular fluorescence with AFM force spectroscopy. Included is a methodology to align the AFM tip and a molecule or other nanoscale object with high accuracy.
    Type: Grant
    Filed: August 8, 2012
    Date of Patent: February 18, 2014
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Sanjeevi Sivasankar, Hui Li
  • ‘Latitude 36 Turf Bermudagrass’
    Patent number: PP24271
    Abstract: ‘Latitude 36 Turf Bermudagrass’ is a clonally propagated F I hybrid from a cross of Cynodon dactylon accession A 12198 (2n=4x=36)×C. transvaalensis OSU selection ‘2747’ (2n=2x=18).
    Type: Grant
    Filed: October 31, 2011
    Date of Patent: February 25, 2014
    Assignee: The Board of Regents for Oklahoma State University
    Inventors: Yanqi Wu, Dennis Loren Martin, Charles M. Taliaferro, Jeffrey A. Anderson, Justin Q. Moss