Patents Assigned to State University
  • Polymeric biomaterials derived from phenolic monomers and their medical uses
    Patent number: 12030983
    Abstract: The present invention provides new classes of phenol compounds, including those derived from tyrosol and analogues, useful as monomers for preparation of biocompatible polymers, and biocompatible polymers prepared from these monomeric phenol compounds, including novel biodegradable and/or bioresorbable polymers. These biocompatible polymers or polymer compositions with enhanced bioresorbabilty and processability are useful in a variety of medical applications, such as in medical devices and controlled-release therapeutic formulations. The invention also provides methods for preparing these monomeric phenol compounds and biocompatible polymers.
    Type: Grant
    Filed: September 15, 2021
    Date of Patent: July 9, 2024
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Joachim B. Kohn, Durgadas Bolikal
  • Catalytic upcycling of polyolefins via versatile alkylaluminums
    Patent number: 12030843
    Abstract: Disclosed herein is a process for the conversion of polymers, oligomers, or mixtures thereof into shorter alkanes, carboxylic acids, alcohols, alkyl halides or aldehydes. This process includes contacting the polymers, oligomers, or mixtures thereof with the compound of formula (I): Al(R1)3??(I) where R1 is independently selected at each occurrence thereof from the group consisting of H, aryl, C1-C8 alkyl, and C1-C8 alkoxy, as a reaction mixture, in the presence of a catalyst selected from the group consisting of a transition metal catalyst, a lanthanide series metal catalyst, or combinations thereof.
    Type: Grant
    Filed: December 17, 2021
    Date of Patent: July 9, 2024
    Assignee: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Aaron David Sadow, Uddhav Kanbur
  • Methods for targeted protein quantification by bar-coding affinity reagent with unique DNA sequences
    Patent number: 12030909
    Abstract: Provided herein are affinity reagents having affinity for particular target, each reagent having a unique DNA barcode, and methods for using the same to measure the abundance of targets in a sample. In particular, methods are provided in which unique barcodes linked to affinity reagents are contacted to a sample to bind antigens if present in said sample. In cases in which the affinity reagents are antibodies and the targets are antigens, antibodies that are bound to their target antigens can be separated from unbound antibodies and the DNA barcode associated with the affinity reagent is amplified, such as with a PCR reaction. In some cases, amplified barcode DNA is subjected to DNA sequencing as a measure of the levels of the target protein in the sample.
    Type: Grant
    Filed: March 6, 2020
    Date of Patent: July 9, 2024
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventor: Joshua LaBaer
  • Method for electronic detection and quantification of antibodies
    Patent number: 12031981
    Abstract: The present disclosure relates to a sensing device and methods for detecting, and quantifying the amount of, a target protein in a sample.
    Type: Grant
    Filed: May 8, 2019
    Date of Patent: July 9, 2024
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Stuart Lindsay, Bintian Zhang
  • METHOD OF TREATMENT FOR PREVENTION OF GLUCOCORTICOID TOXICITY AND/OR ENHANCEMENT OF MUSCLE REGENERATION VIA NEUTROPHIL ELASTASE INHIBITION
    Publication number: 20240216353
    Abstract: The present disclosure is directed to methods of treatment, including treatment of a myopathy by administering to a subject in need thereof an elastase inhibitor in combination with a glucocorticoid. The present disclosure is also directed to pharmaceutical compositions that include an elastase inhibitor that can be used in such treatment.
    Type: Application
    Filed: January 31, 2024
    Publication date: July 4, 2024
    Applicants: The Research Foundation for The State University of New York, The University of Liverpool
    Inventors: Addolorata Pisconti, Fiona Kate Jones, Kirsty Anne Johnson
  • UNIVERSAL VACCINE PLATFORM
    Publication number: 20240216502
    Abstract: The disclosure relates to vaccination compositions, for example, against human papillomavirus, Zika virus, and flu virus. The disclosure also relates to vectors for producing the virus-like particles and immune complex platforms of the vaccination compositions.
    Type: Application
    Filed: November 8, 2023
    Publication date: July 4, 2024
    Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Hugh MASON, Andrew DIAMOS, Mary PARDHE, Brandon FAVRE
  • SULFATED OLIGOSACCHARIDES HAVING ANTI-INFLAMMATORY ACTIVITY
    Publication number: 20240216419
    Abstract: Provided herein are small molecule compounds, including non-anticoagulant heparan sulfate oligosaccharide molecules, having anti-inflammatory properties and capable of interacting with high mobility group box 1 (HMGB1) proteins in a manner sufficient to affect an interaction between the HMGB1 protein and a receptor for advanced glycation end products (RAGE). Also provided herein are methods of treating Paracetamol (APAP) overdose in subjects.
    Type: Application
    Filed: January 8, 2024
    Publication date: July 4, 2024
    Applicants: The University of North Carolina at Chapel Hill, THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: Katelyn Arnold, Ding Xu, Yongmei Xu, Rafal Pawlinski, Jian Liu
  • High Sb Concentration GaAsSb/GaAs(1-x)SbxN/GaAlAs Core-Shell-Shell Nanowires
    Publication number: 20240218563
    Abstract: Compositions comprising Group V/III nanowires, and methods of making such nanowires are described. Some compositions comprise one or more core-shell nanowires comprising a core and a first shell surrounding or substantially surrounding the core. The core is formed from GaAs(1?y)Sby, where y=about 0.03-0.07 and the first shell is formed from GaAs(1?x)SbxN, where x=0.27-0.34. The nanowires have an average emission maximum of 1.4-1.7 ?m. Some nanowires further comprise a second shell surrounding or substantially surrounding the first shell. The second shell is formed from a Group V/III material such as Ga1?mAlmAs, where m=0-0.2. Some nanowires have the structure GaAs(0.93-0.97)Sb(0.03-0.07)/GaAS(0.66-0.73)Sb(0.27-0.34)N/Ga(0.8-1)Al(0-0.2)As.
    Type: Application
    Filed: January 29, 2024
    Publication date: July 4, 2024
    Applicant: North Carolina A&T State University
    Inventors: Shanthi Iyer, Jia Li, Prithviraj Deshmukh, Manish Sharma
  • Methods of forming stacked integrated circuits using selective thermal atomic layer deposition on conductive contacts and structures formed using the same
    Patent number: 12027488
    Abstract: Methods of bonding and structures with such bonding are disclosed. One such method includes providing a first substrate with a first electrical contact; providing a second substrate with a second electrical contact above the first electrical contact, wherein an upper surface of the first electrical contact is spaced apart from a lower surface of the second electrical contact by a gap; and depositing a layer of selective metal on the lower surface of the second electrical contact and on the upper surface of the first electrical contact by a thermal Atomic Layer Deposition (ALD) process until the gap is filled to create a bond between the first electrical contact and the second electrical contact.
    Type: Grant
    Filed: September 9, 2021
    Date of Patent: July 2, 2024
    Assignees: The Regents of the University of California, Wayne State University, Georgia Tech Research Corporation
    Inventors: Mike Breeden, Victor Wang, Andrew Kummel, Ming-Jui Li, Muhannad Bakir, Jonathan Hollin, Nyi Myat Khine Linn, Charles H. Winter
  • Low fiber Pennycress meal, seeds, and methods of making
    Patent number: 12022848
    Abstract: Pennycress seed, seed lots, and seed meal having reduced fiber content and improved suitability for use in producing animal feed are provided.
    Type: Grant
    Filed: March 16, 2023
    Date of Patent: July 2, 2024
    Assignees: COVERCRESS INC., BOARD OF TRUSTEES OF ILLINOIS STATE UNIVERSITY, REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Tim Ulmasov, Gary Hartnell, John C. Sedbrook, Michael David Marks, Ratan Chopra, Maliheh Esfahanian
  • Dual-screen digital radiography with asymmetric reflective screens
    Patent number: 12025757
    Abstract: Structures operable to detect radiation are described. The structure may two screens with a phosphor layer, respective. The structure may further include a photosensor array disposed between the first screen and the second screen such that the photosensor array directly contacts the first screen or is directly attached to the first screen using an optical adhesive and directly contacts the second screen or is directly attached to the second screen using an optical adhesive.
    Type: Grant
    Filed: August 23, 2022
    Date of Patent: July 2, 2024
    Assignee: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: Anthony Lubinsky, Wei Zhao, John A. Rowlands, Adrian Howansky
  • Methods of classifying response to immunotherapy for cancer
    Patent number: 12025615
    Abstract: Provided herein are methods for classifying how a subject having a cancer will respond to immunotherapeutic (IT) therapy based on the subject's immunosignature or frameshift signature. Also provided herein are methods for classifying a subject having a cancer as having a good prognosis or a poor prognosis based on the subject's immunosignature or frameshift signature.
    Type: Grant
    Filed: September 13, 2018
    Date of Patent: July 2, 2024
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventor: Stephen Johnston
  • Composition comprising self-stratifying amphiphilic Janus particles
    Patent number: 12023641
    Abstract: The disclosure relates to a composition comprising amphiphilic Janus particles and a waterborne binder, wherein the particles are self-stratified, and methods of making and using the same. The disclosure also relates to the synthesis of amphiphilic Janus particles.
    Type: Grant
    Filed: January 4, 2023
    Date of Patent: July 2, 2024
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Yifan Li, Shan Jiang
  • Methods and systems for measuring tissue impedance and monitoring PVD treatment using neuro-implants with improved ultrasound powering
    Patent number: 12023499
    Abstract: Methods and systems for measuring tissue impedance and monitoring PVD treatment using neuro-implants with improved wireless powering are disclosed. In some embodiments, an implanted device including a wireless energy receiver, a demodulation circuit, and electrodes may be configured to received modulated energy from an energy transmitter. The implanted device may convert the energy to an electrical voltage to be applied to tissue to adjust the tissue's impedance. The tissue impedance may be measured with a computing system by receiving and processing an energy signal emitted/produced in response to the electrical voltage applied by the implanted device. In some embodiments, improved microwave powering schemes may be utilized to power the implanted device. In some embodiments, improved ultrasound powering schemes may be utilized to power the implanted device.
    Type: Grant
    Filed: January 20, 2021
    Date of Patent: July 2, 2024
    Assignee: Arizona Board of Regents on Behalf of Arizona State University
    Inventor: Bruce C. Towe
  • Bronchoscopic-based microwave ablation system and method
    Patent number: 12023093
    Abstract: A novel microwave ablation applicator includes a flexible tubular shaft and a partially encapsulated antenna. The applicator is adapted to be used with an endoscope in order to access remote targets deep within an organ of a patient. Microwave power is emitted from the antenna in a desired radiation pattern by circulating an attenuating liquid through the shaft and across a portion of the antenna. Microwave ablation systems and methods are described.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: July 2, 2024
    Assignees: Broncus Medical Inc., Kansas State University Research Foundation
    Inventors: Austin Pfannenstiel, Thomas M Keast, Henky Wibowo, Punit Prakash
  • Methods and apparatus for efficiently rendering, managing, recording, and replaying interactive, multiuser, virtual reality experiences
    Patent number: 12026824
    Abstract: In some embodiments, an apparatus includes a volatile memory, a non-volatile memory, a first processor coupled to the non-volatile memory and configured to receive a data set associated with an object and user information associated with a spatial position of a user in a multi-user virtual (IMVR) environment, and a second processor coupled to the volatile memory, the second processor configured to render an instance of the portion of the object in the IMVR environment from a perspective of the user based on the spatial position of the user. The first processor is configured to generate a look-up table (LUT) based on a set of inputs received from a user. The second processor is configured to render, based on the LUT and information related to a manipulation by a user, an updated instance of the portion of the object that manifests an effect of the manipulation in the IMVR environment.
    Type: Grant
    Filed: July 15, 2022
    Date of Patent: July 2, 2024
    Assignee: Colorado State University Research Foundation
    Inventors: Tod Robert Clapp, Brendan Garbe, Chad Eitel
  • Composition and method for enhancing photosynthetic efficiency, growth and/or lipid production of microorganisms
    Patent number: 12024704
    Abstract: Compositions including metal nano- and/or micro-particles in solution with photosynthetic bioproduct producing microorganisms. These light harvesting complexes increase growth rates and photosynthetic efficiency of the constituent microorganisms, reducing the light required for a specific production level, or increases production for a specific light level. Compositions including zero-valent iron nanoparticles (nZVIs) in solution with photosynthetic bioproduct producing microorganisms. The nZVIs cause increased growth, lipid production and fatty acid production.
    Type: Grant
    Filed: December 12, 2019
    Date of Patent: July 2, 2024
    Assignee: Morgan State University
    Inventors: Viji Sitther, Somayeh Fathabad
  • Method of additively manufacturing an integrated circuit of an interconnect packaging structure
    Patent number: 12027477
    Abstract: A method of manufacturing an interconnect packaging structure is provided. In one aspect, the method includes forming a first body defining a cavity around at least one integrated circuit using an additive manufacturing machine, depositing a conductive transmission line on the first body and electrically coupling the conductive transmission line and the at least one integrated circuit with a conductive interconnect.
    Type: Grant
    Filed: May 15, 2019
    Date of Patent: July 2, 2024
    Assignee: Board of Trustees of Michigan State University
    Inventors: Ioannis Papapolymerou, Premjeet Chahal, John D. Albrecht, Michael Thomas Craton, Christopher Oakley
  • plant named ‘Cascade Jewel’
    Patent number: PP35894
    Abstract: A new Vaccinium ovatum plant distinguished by its upright and vigorous, yet compact growth habit, dense branching, and DNA content (tetraploid).
    Type: Grant
    Filed: June 26, 2023
    Date of Patent: July 2, 2024
    Assignee: Oregon State University
    Inventor: Ryan N. Contreras
  • plant named ‘ORSTPHILx1’
    Patent number: PP35914
    Abstract: A new Philadelphus variety distinguished by its upright and vigorous, yet compact growth habit, dense branching, deep green foliage late into the season, and prolific flower production.
    Type: Grant
    Filed: June 26, 2023
    Date of Patent: July 2, 2024
    Assignee: Oregon State University
    Inventor: Ryan N. Contreras