Patents Assigned to State University
  • Apparatus and methods for synthesizing biopolymers
    Patent number: 12017195
    Abstract: The present disclosure provides an apparatus for synthesizing a biopolymer, a method for preparing an apparatus for synthesizing a biopolymer, and a method of synthesizing a biopolymer. The apparatus comprises (a) a substrate comprising atop surface and a plurality of wells, wherein each of the plurality of wells comprises a first electrode disposed on the bottom of the well and a linker attached to the sides of the well; and (b) a fluidic chamber system disposed on the top surface of the substrate.
    Type: Grant
    Filed: July 1, 2019
    Date of Patent: June 25, 2024
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Quan Qing, Ching-wei Tsao, Peiming Zhang
  • Methods of modifying cellulose crystallinity
    Patent number: 12018099
    Abstract: The present disclosure provides methods of controlling the size of cellulose crystals by mixing a first composition comprising cellulose and coagulating this mixture with varying concentrations of hydrogen peroxide.
    Type: Grant
    Filed: March 31, 2021
    Date of Patent: June 25, 2024
    Assignees: Rutgers, The State University of New Jersey, Rowan University
    Inventors: David Salas de la Cruz, Xiao Hu, Stacy Love, David Verrill
  • Methods and compositions for identifying neoantigens for use in treating cancer
    Patent number: 12018252
    Abstract: Provided herein, are methods of identifying neoantigens for treating and preventing cancer. Also disclosed are methods and compositions for administering identified neoantigens for the treatment and prevention of cancer.
    Type: Grant
    Filed: April 1, 2022
    Date of Patent: June 25, 2024
    Assignee: Arizona Board of Regents on Behalf of Arizona State University
    Inventors: Stephen Albert Johnston, Luhui Shen
  • Laser system for blood or tissue assessment
    Patent number: 12019011
    Abstract: A laser system for blood assessment is provided. Another aspect of a laser system includes a container within which is blood, a laser operable to emit a laser beam at the container to vibrate the blood, a detector operable to detect a vibrational characteristic of the blood, a controller connected to the detector operable to automatically determine a characteristic of the blood based at least in part on the vibrational characteristic detected by the detector, and a display operable to indicate a determination result from the controller. Another aspect of the present blood or tissue assessment laser system includes a laser, a power supply, a detector, a controller and an electronic display, all contained within or coupled to a handheld and portable housing.
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: June 25, 2024
    Assignee: Board of Trustees of Michigan State University
    Inventor: Marcos Dantus
  • Process for producing a glucuronide and genetically modified microorganisms useful in this process
    Patent number: 12018307
    Abstract: The present invention relates to an in vitro or in vivo process for producing a glucuronide comprising a glucuronic acid moiety bound to a phenolic hydroxyl group or a phenolic carboxyl group. Also provided are expression vectors, nucleic acids, polypeptides, and recombinant microbial cells useful in carrying out the process and prodrugs produced by the process.
    Type: Grant
    Filed: August 26, 2022
    Date of Patent: June 25, 2024
    Assignee: UTAH STATE UNIVERSITY
    Inventor: Jixun Zhan
  • Controlled wetting and spreading of metals on substrates using porous interlayers and related articles
    Patent number: 12022610
    Abstract: The disclosure generally relates to a method of creating patterned metallic circuits (e.g., silver circuits) on a substrate (e.g., a ceramic substrate). A porous metal interlayer (e.g., porous nickel) is applied to the substrate to improve wetting and adhesion of the patterned metal circuit material to the substrate. The substrate is heated to a temperature sufficient to melt the patterned metal circuit material but not the porous metal interlayer. Spreading of molten metal circuit material on the substrate is controlled by the porous metal interlayer, which can itself be patterned, such as having a defined circuit pattern. Thick-film silver or other metal circuits can be custom designed in complicated shapes for high temperature/high power applications. The materials designated for the circuit design allows for a low-cost method of generating silver circuits other metal circuits on a ceramic substrate.
    Type: Grant
    Filed: February 10, 2022
    Date of Patent: June 25, 2024
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Jason Dale Nicholas, Quan Zhou, Thomas Rector Bieler
  • Warp knit fabric for textile and medical applications and methods of manufacturing the same
    Patent number: 12018414
    Abstract: A warp knitted fabric formed by a warp knitting machine includes a first knitted portion formed using a first knitting sequence in a machine direction, the first knitted portion formed of a set of continuous textile strands, and a second knitted portion formed of the set of continuous textile strands using a second knitting sequence in the machine direction, the second knitted portion comprising at least two strips extending lengthwise in the machine direction and detached from one another along their lengthwise edges. The first knitted portion and the second knitted portion alternate sequentially in the machine direction. The second knitting sequence differs from the first knitting sequence in that at least one cross connecting stitch is dropped to form the at least two strips.
    Type: Grant
    Filed: April 14, 2021
    Date of Patent: June 25, 2024
    Assignees: Duke University, North Carolina State University
    Inventors: Howard Levinson, James Brian Davis, Don Ward, Jon Rust
  • Pinched tubes for reconfigurable robots
    Patent number: 12017347
    Abstract: A device includes a tube and a sleeve configured to at least partially encircle a portion the tube along its length. The tube is flexible and airtight and defines a longitudinal axis along a center of the tube, and is configured to bend along the longitudinal axis upon at least partial evacuation of the tube to form a joint. The joint defines a joint angle relative to the longitudinal axis, thereby approximating a revolute joint with torsional stiffness. Actuating a joint includes partially evacuating a flexible tube defining a longitudinal axis, thereby forming a bend in the tube at an angle with respect to the longitudinal axis at a perimeter of a rigid sleeve at least partially encircling the tube, and restoring a neutral pressure to the tube, thereby removing the bend in the tube.
    Type: Grant
    Filed: October 21, 2022
    Date of Patent: June 25, 2024
    Assignees: Arizona Board of Regents on behalf of Arizona State University, The Regents of the University of California
    Inventors: Daniel Aukes, Mohammad Sharifzadeh, Yuhao Jiang, Nicholas Gravish, Mingsong Jiang
  • Organic-inorganic hybrid bulk assemblies and methods
    Patent number: 12018193
    Abstract: Bulk assemblies are provided, which may have desirable photoluminescence quantum efficiencies. The bulk assemblies may include two or more metal halides, and a wide band gap organic network. The wide band gap organic network may include organic cations. The metal halides may be disposed in the wide band gap organic network. Light emitting composite materials also are provided.
    Type: Grant
    Filed: March 8, 2023
    Date of Patent: June 25, 2024
    Assignee: Florida State University Research Foundation, Inc.
    Inventors: Biwu Ma, Chenkun Zhou, Haoran Lin, Yu Tian
  • SYSTEMS AND METHODS FOR IMPLANTABLE SELF-MONITORING SYSTEMS TO DETECT PRESSURE AND FLOW CHARACTERISTICS
    Publication number: 20240198064
    Abstract: A valve device monitoring system for at-home human-in-the-loop hydrocephalus shunt monitoring detects degradation and imminent failure of implantable devices for the treatment of hydrocephalus. Potential mechanisms for failure are presented and associated with observable parameters. The valve device monitoring system enables at-home testing using a non-invasive monitoring methodology. Development of a behavioral model of the valve device monitoring system involves a tightly-coupled valve design and behavioral characterization process aimed at reducing unnecessary monetary, material, animal welfare, and computational costs.
    Type: Application
    Filed: December 15, 2023
    Publication date: June 20, 2024
    Applicant: Arizona Board of Regents on Behalf of Arizona State University
    Inventors: Jennifer Blain Christen, Daniel Gulick, Sule Ozev
  • THIENYL-DIBENZOAZEPINES AND THEIR DERIVATIVES AS DONORS FOR XANTHENE-BASED SHORT-WAVE INFRARED (SWIR) DYES
    Publication number: 20240199882
    Abstract: A near infrared dye comprising a counterion and a structure of Formula I wherein the at least one of R1 and R2 are selected from dibenzazepinyl, thienyldibenzazepine, bithienyldibenzazepine, thienodibenzazepine, dihydrodibenzazepinyl, thienyldihydrodibenzazepine, bithienyldihydrodibenzazepine, and thienodihydrodibenzazepine, and X, R, R3-R4, R19, R20 and R22-R29 are as disclosed herein. Materials and compositions comprising the SWIR dye can absorb light at a wavelength of 800 nm to 1400 nm and release the energy in the form of light (fluorescence) or heat (non-radiative). The dyes can also convert the absorbed light to heat and ultrasound waves via the photoacoustic effect. The photoacoustic effect can be used in photoacoustic tomography to image biological materials or processes. Methods for synthesizing the SWIR dyes and materials comprising the same are also disclosed.
    Type: Application
    Filed: November 30, 2023
    Publication date: June 20, 2024
    Applicant: Mississippi State University
    Inventors: Colleen N. Scott, Chathuranga S. L. Rathnamalala
  • Anomaly Detection on MIL-STD-1553 Dataset Using Machine Learning
    Publication number: 20240202326
    Abstract: The ability of several machine learning models to detect attacks that emulate normal non-periodical messages in the MIL-STD-1553 communication traffic were evaluated and the technical problems were identified, such as, for example, that the MIL-STD-1553 dataset is highly imbalanced and most models simply fail or produce poor results when classifying the data. Different machine learning algorithms were trained and then used to classify the MIL-STD-1553 dataset. A unique metric was advantageously identified to judge the performance of the machine learning models applied to highly imbalanced datasets.
    Type: Application
    Filed: December 15, 2022
    Publication date: June 20, 2024
    Applicant: Bowie State University
    Inventors: Darsana Josyula, Francis Onodueze
  • Rice Cultivar Designated 'Addi Jo'
    Publication number: 20240196827
    Abstract: The rice cultivar designated ‘Addi Jo’ and its hybrids and derivatives are disclosed.
    Type: Application
    Filed: December 16, 2022
    Publication date: June 20, 2024
    Applicant: Board of Supervisors of Louisiana State University
    Inventor: Adam Famoso
  • Instrumented trail making task (iTMT)
    Patent number: 12011282
    Abstract: An instrumented trail-making task (iTMT) platform includes a wearable sensor and interactive interface technology configured to identify cognitive-cognitive impairment in individuals such as older adults. The iTMT platform may be programmed with neuropsychological tests for assessing individuals. The iTMT may provide information on visual search, scanning, speed of processing, mental flexibility, and/or executive functions as well as physical biomarkers of motor performance including slowness, weakness, exclusion, and/or motor planning error. Results of tests administered by the iTMT system may be reported to a patient or caregiver and used in identifying cogni-tive-motor impairment among individuals suffering from cognitive impairment, dementia, and/or those with frailty status, and/or cognitive frailty, and/or high risk of falling, and/or high likelihood of decline in cognitive-motor over time.
    Type: Grant
    Filed: September 18, 2017
    Date of Patent: June 18, 2024
    Assignees: Baylor College of Medicine, Arizona Board of Regents on behalf of Arizona State University, The United States of America as represented by the Department of Veterans Affairs
    Inventors: Bijan Najafi, Javad Razjouyan, He Zhou, Mark Kunik
  • Conductive graphene matrix-encapsulated cells
    Patent number: 12012609
    Abstract: Various embodiments disclosed relate to conductive graphene matrix-encapsulated cells. A matrix-encapsulated cell includes an encapsulating polymer matrix including a biopolymer and graphene. The matrix-encapsulated cell also includes one or more of the cells encapsulated within the encapsulating polymer, wherein the graphene directly contacts at least some of the cells. The matrix encapsulating the one or more cells is electrically conductive.
    Type: Grant
    Filed: May 9, 2023
    Date of Patent: June 18, 2024
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Nicole Nastaran Hashemi, Reza Montazami, Marilyn Christine McNamara, Jasmin Okuzono
  • Methods and devices for reducing vascular smooth muscle cell proliferation
    Patent number: 12011508
    Abstract: In one aspect, the disclosure relates to compositions, methods, and devices pertaining to polymeric nanoparticle compositions (pNP), pNP compositions comprising a therapeutic agent, devices comprising a drug-coated balloon comprising a disclosed pNP comprising a therapeutic agent, and methods for treating peripheral artery disease using the disclosed compositions and devices. In further aspects, the pNP comprises a poly (lactic-co-glycolic) acid possessing a positive charge for firm attachment to the balloon matrix, followed by adhesion to the negatively charged bilayer of the vascular wall. In still further aspects, the therapeutic agent comprises a resveratrol or derivative thereof, a quercetin or derivative thereof, or combinations thereof. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
    Type: Grant
    Filed: February 1, 2019
    Date of Patent: June 18, 2024
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Tammy Renee Dugas, Cristina Sabliov, Carlos Astete
  • System and method for determining position of a steerable assembly within tissue of an animal body
    Patent number: 12011233
    Abstract: A system and method for determining position of a steerable assembly within tissue of an animal body utilizes an elongated body structure with an implement arranged at a distal end thereof, and a premagnetized material proximate to the distal end. A signal indicative of a length of insertion of the elongated body structure into the tissue is used with a signal indicative of (i) force, strain, shape of a sensor associated with the elongated body structure and/or (ii) directionality of magnetic field applied to the premagnetized material, to determine a three-dimensional (3D) trajectory of the steerable assembly. The 3D trajectory is superimposed on a 3D model of the tissue to determine position of the steerable assembly within the tissue.
    Type: Grant
    Filed: November 25, 2020
    Date of Patent: June 18, 2024
    Assignee: Arizona Board of Regents on Behalf of Arizona State University
    Inventors: Hamidreza Marvi, Mahdi Ilami
  • Antibacterial and protective bacteriophage formulations and methods for making and using them
    Patent number: 12012617
    Abstract: Provided are compositions and methods for treating, ameliorating and preventing infections, disorders and conditions in mammals, including genetically-predisposed and chronic disorders, where a microbial or bacterial flora is at least one causative or symptom-producing factor. Provided are compositions and methods used to treat, prevent or ameliorate an infection, for example, an infection in the gastrointestinal tract, or bowel.
    Type: Grant
    Filed: November 23, 2021
    Date of Patent: June 18, 2024
    Assignee: San Diego State University (SDSU) Foundation
    Inventors: Forest Rohwer, Jeremy J. Barr
  • plant named ‘NCXC1’
    Patent number: PP35880
    Abstract: A new and distinct cultivar of x Chitalpa plant named ‘NCXC1’ is disclosed, characterized by large inflorescences with vibrant purple flowers, and small tree habits. The new variety is an x Chitalpa, typically produced as an outdoor ornamental plant.
    Type: Grant
    Filed: June 6, 2023
    Date of Patent: June 25, 2024
    Assignee: North Carolina State University
    Inventors: Thomas Green Ranney, Richard Olsen, Andra Windorf Nus, Irene Palmer, Nathan P. Lynch
  • plant named ‘NCLJ1’
    Patent number: PP35881
    Abstract: A new and distinct cultivar of Ligustrum plant named ‘NCLJ1’ is disclosed, characterized rounded upright habit, white flowers, glossy evergreen foliage, and no apparent female fertility. The new variety is a Ligustrum, typically produced as an outdoor ornamental plant.
    Type: Grant
    Filed: June 6, 2023
    Date of Patent: June 25, 2024
    Assignee: North Carolina State University
    Inventors: Thomas Green Ranney, Andra Windorf Nus, Irene Palmer, Nathan P. Lynch