Patents Assigned to State University
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Patent number: 9346835Abstract: A compound includes the structure of general Formula (II), pharmaceutically acceptable salts thereof, and/or solvates thereof: wherein R1, R2, R3, are independently selected from the group consisting of null, hydroxy, alkoxy, and halo, or R1 and R2 taken together form a cyclic boronate ester and R3 is null; wherein when four bonds to boron are present, boron bears a formal negative charge and the structure further comprises a countercation that is potassium or sodium, X1, X2, X3, and X4 are independently selected from the group consisting of O, CH, and N, with the proviso that no more than two of combined O and N are selected, and Z is selected from the group consisting of hydrogen, alkyl, aryl, heteroaryl, and halogen, any of which may be optionally substituted. Such compounds can increase glucose uptake by cells and preferably do not substantially increase adipogenesis.Type: GrantFiled: October 16, 2013Date of Patent: May 24, 2016Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical CollegeInventors: Nikhil V. Dhurandhar, Bhaskar C. Das
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Patent number: 9345662Abstract: This invention concerns an in situ biodegradable hydrogel drug delivery system in which the components are assembled in a manner that provides a mechanism for the timed cleavage of a particular amide bond in a covalently linked active agent or of the hydrogel structure.Type: GrantFiled: November 20, 2009Date of Patent: May 24, 2016Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEYInventors: Patrick J. Sinko, Manjeet Deshmukh, Yashveer Singh, Simi Gunaseelan
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Patent number: 9345688Abstract: The present disclosure relates to methods and compositions for modulating the activity of KCNQ channels as a means for reducing the effects of aberrant KCNQ channel function associated with epilepsy, deafness and arrhythmias including but not limited to, Long-QT syndrome (“LQTS”), and atrial fibrillation. The present disclosure also relates to the discovery of certain regions of KCNQ channels that interact with various channel stimulating molecules such as, ATP, and PIP2, as well as KCNQ channel domains that effect voltage dependant channel activation. The disclosure is also directed to the use of small molecules to modulate KCNQ channel activity in a cell. Moreover, the present disclosure relates to the therapeutic effects of treating a subject with modulators of KCNQ channel activity.Type: GrantFiled: March 14, 2014Date of Patent: May 24, 2016Assignees: Washington University, The Research Foundation for The State University of New York, Curators of the University of MissouriInventors: Jianmin Cui, Ira S. Cohen, Xiaoqin Zou
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Patent number: 9345232Abstract: Electronic components, including a transceiver (220) for two-way wireless communications, are carried by a freely roaming animal (190) such as a rat. Electrodes are implanted in the brain of the animal to provide cues and rewards to the animal to achieved desired behaviors, including controlling the direction and speed of movement of the animal, and training the animal to recognize odors. Network interface components (265) allow a network of the animals to work together. Sensors (225, 230, 235, 245, 255, 260) carried by the animal provide information to a remote base station regarding, e.g., heading and location. Chemical or gas sensors, along with a video camera and a microphone provide information regarding an environment of the animal. The animal can search for people buried in rubble piles, and detect explosives, chemicals or other dangerous materials. A vehicle (500) for deploying the animal is also provided.Type: GrantFiled: November 2, 2012Date of Patent: May 24, 2016Assignee: The Research Foundation for The State University of New YorkInventors: John K. Chapin, Timothy L. Hanson, Linda Hermer, Raymond Vazquez
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Patent number: 9345746Abstract: The present invention relates to methods and compositions for the treatment and prevention of diarrhea and diarrheal related diseases and disorders in both animals and humans. In some embodiments, the invention relates to the treatment of said diarrhea and diarrheal related diseases and disorders with a vaccine. In still further embodiments, the invention relates to the treatment of constipation using the disclosed methods and compositions.Type: GrantFiled: February 21, 2014Date of Patent: May 24, 2016Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITYInventor: A. Mahdi Saeed
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Publication number: 20160135435Abstract: Many types of artificial reefs have been deployed in the world's oceans, bays and estuaries. These range from sinking ships to dispersing old building debris. In most approaches, the material placed in the marine environment lacks any nutrients needed for growth or concern regarding proper chemical conditions necessary to start and sustain life. In this discovery, concrete is made from both inorganic and organic components. The inorganic components are selected to include species that will be used to create a receptive surface to start and sustain life. Moreover, other conditions such as pH, chemical toxicity, nutrient levels and biodegradability are considered in the formulation. Additionally, there is an organic component that is part of the concentration mixture which provides trace nutrients and serves to weaken the structures so it will biodegrade over time. The biodegradable concrete slowly releases small quantities of resources (over months and years) providing a steady flux of essential nutrients.Type: ApplicationFiled: November 13, 2014Publication date: May 19, 2016Applicant: Valdosta State University, University System of GeorgiaInventors: Thomas Manning, Brittany Butler, Mehulkumar Patel, Sydney Plummer, Tess Baker
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Publication number: 20160140865Abstract: Device for training people to a preferred posture during normal gait comprising of: at least a base for stabilizing at least one rail or post coupled to said base at least one gait regulating component, which will be arranged perpendicularly with respect to said rod or post and parallel to the floor surface, with said gait regulating component provided for defining an obstacle during the normal gait of a user to impose on the latter a predetermined movement of the foot, knee, and hip, facilitating the maintenance of the user's bust erected in a position of equilibrium, with the consequent lengthening of the pushing leg, the gradual transition of the weight of the user's body by the supporting foot posterior to that of the advancing leg, and the oscillation of the arm forward opposite to the lower limb that moves, with a final effect of a steady pace.Type: ApplicationFiled: November 12, 2015Publication date: May 19, 2016Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITYInventors: Sandro Marzetti, Caterina Germani, Marco Santello
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Publication number: 20160135452Abstract: A method of converting lignin to phenolic compounds and dicarboxylates in high yield is described. The method involves the use of peroxy acids to react with lignin at a moderated treatment conditions. The peroxy acids can be used along or in combination of other catalysts that have the capability to lower the molecular weight of lignin. A phenolic compounds yield is achieved (>60%) and these phenolic compounds represents high value precursors for various applications include but not limited to antioxidants, health improvement agents, anticorrosive agents, liquid fuel components and performance enhancing agents, resin and adhesives. Dicarboxylic acids can be used for polymer applications or hydrodeoxygenation to hydrocarbon fuel.Type: ApplicationFiled: June 14, 2013Publication date: May 19, 2016Applicant: WASHINGTON STATE UNIVERSITYInventor: Xiao ZHANG
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Publication number: 20160140706Abstract: The system and method of the invention utilizes computer software to determine an estimation of the age of an animal by measuring, analyzing, comparing, calculating, and presenting age features and the age of animals such as deer, moose, elk, bovids, pronghorns and the like from digital data and/or photographs of the animals.Type: ApplicationFiled: September 30, 2015Publication date: May 19, 2016Applicant: Mississippi State UniversityInventors: Stephen Demarais, Bronson K. Strickland, Jeremy Flinn
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Publication number: 20160141481Abstract: Thermoelectric materials based on tetrahedrite structures for thermoelectric devices and methods for producing thermoelectric materials and devices are disclosed. The thermoelectric device has a pair of conductors and a p-type thermoelectric material disposed between the conductors. The thermoelectric material is at least partially formed of a hot pressed high energy milled tetrahedrite formed of tetrahedrite ore and pure elements to form a tetrahedrite powder of Cu12-xMxSb4S13 disposed between the conductors, where M is at least one of Zn and Fe.Type: ApplicationFiled: July 3, 2014Publication date: May 19, 2016Applicant: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITYInventors: Donald T. MORELLI, Xu LU
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Patent number: 9339559Abstract: A contrast agent having a contrast protein have contrast properties and at least one targeting moiety, wherein the at least one targeting moiety is operatively linked to or incorporated within the contrast protein. Methods for targeting contrast agents and for preparing such agents are included.Type: GrantFiled: September 8, 2006Date of Patent: May 17, 2016Assignee: Georgia State University Research Foundation, Inc.Inventors: Jenny J. Yang, Zhi-Ren Liu
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Patent number: 9340426Abstract: The present disclosure relates to reactive modified lignin, methods of preparing such modified lignin, and materials, such as polymer systems, incorporating the modified lignin. More specifically, the lignin can be modified by selectively masking reactive functional groups such that the material has a modulated reactivity and is thus better suited for incorporation into and/or formation of further materials, such as carbon fibers.Type: GrantFiled: February 20, 2013Date of Patent: May 17, 2016Assignee: North Carolina State UniversityInventor: Dimitris S. Argyropoulos
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Patent number: 9340792Abstract: Methods and compositions for treating or preventing inflammatory disorders are provided. The compositions of the invention comprise a recombinant bacterium genetically modified to decrease the display of lipoteichoic acid on the cell surface. Methods of the invention comprise administering to a subject a recombinant bacterium modified to decrease the display of lipoteichoic acid on the cell surface. Administration of the recombinant bacterium promotes a desired therapeutic response. The recombinant bacterium may be administered in a single dose or series of doses. Methods of the invention find use in treating or preventing a variety of inflammatory disorders including, for example, treating or preventing inflammatory bowel disease, colitis, or Crohn's disease.Type: GrantFiled: June 16, 2011Date of Patent: May 17, 2016Assignees: North Carolina State University, Northwestern UniversityInventors: Todd R. Klaenhammer, Erika Pfeiler, Mansour Mohamadzadeh
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Patent number: 9343533Abstract: The invention generally related to a method for preparing a layer of graphene directly on the surface of a semiconductor substrate. The method includes forming a carbon-containing layer on a front surface of a semiconductor substrate and depositing a metal film on the carbon layer. A thermal cycle degrades the carbon-containing layer, which forms graphene directly upon the semiconductor substrate upon cooling. In some embodiments, the carbon source is a carbon-containing gas, and the thermal cycle causes diffusion of carbon atoms into the metal film, which, upon cooling, segregate and precipitate into a layer of graphene directly on the semiconductor substrate.Type: GrantFiled: October 8, 2014Date of Patent: May 17, 2016Assignees: SunEdison Semiconductor Limited (UEN201334164H), Kansas State University Research FoundationInventors: Michael R. Seacrist, Vikas Berry
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Patent number: 9344358Abstract: For aging-aware routing, an aging module calculates an aging score for links and routers in a Network-on-Chip for a previous epoch. A routing module dynamically routes a flow through the links and the routers to satisfy routing criteria including a least total aging score for the links and the routers of the flow.Type: GrantFiled: March 11, 2013Date of Patent: May 17, 2016Assignee: Utah State UniversityInventors: Kshitij Bhardwaj, Koushik Chakraborty, Sanghamitra Roy
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Patent number: 9341609Abstract: A monitoring assembly (201) with an intake (213) has at least one pump (210) featuring at least one pump channel mounted in the monitoring assembly (201). A plurality of fluid lines are coupled to the at least one pump (210). At least one filter cartridge (315) is also mounted in the assembly. Each filter cartridge (315) is separately coupled by one of the plurality of fluid lines to one of the pump channels, where each filter cartridge (315) contains material for extracting an analyte, and where the at least one pump operates to separately push fluid through the at least one filter cartridge (315). The filter cartridge (315) operates to separate fluid into constituent parts.Type: GrantFiled: May 4, 2011Date of Patent: May 17, 2016Assignee: ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITYInventor: Rolf U. Halden
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Patent number: 9340678Abstract: One disclosed embodiment concerns an aqueous inorganic coating precursor solution comprising a mixture of water, polynuclear aluminum hydroxide cations, and polyatomic ligands selected from nitrate (NO3?), nitrite (NO2?), or combinations thereof. In certain embodiments, the composition has a molar concentration ratio of polyatomic ligands to aluminum of less than 3; an aluminum cation concentration of from about 0.01 M to about 3.5 M; and/or a polyatomic anion concentration of from about 0.1 to about 2.5 times the aluminum cation concentration. Embodiments of a method for forming the precursor solution also are disclosed. For example, certain embodiments comprise adding a metal having a sufficient reduction potential to reduce nitric acid to an aqueous solution comprising aluminum nitrate (Al(NO3)3).Type: GrantFiled: June 14, 2011Date of Patent: May 17, 2016Assignee: State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State UniversityInventors: Douglas A. Keszler, Wei Wang
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Patent number: 9341835Abstract: The virtual telemicroscope system (VTS) of the present invention captures an entire image of a specimen on a test slide as an original high power image, signal processes the original high power image to generate a low power background image, generates an initial virtual slide based on the low power background image and posts and/or transmits the initial virtual slide to a remote user enabling the remote user to view the low power background image on a remote user's computer screen. While viewing the initial virtual slide, the remote user may identify (i.e., select) one or more specific areas on the background image and request the service provider to provide detailed images (e.g., higher magnified image than the background image) at the defined locations. In response, the VTS provides the remote user with the requested partial high power image by simply signal processing the original high power image and generating a secondary virtual slide based on the newly processed image.Type: GrantFiled: July 16, 2009Date of Patent: May 17, 2016Assignee: The Research Foundation of State University of New YorkInventors: Jiang Gu, Virginia M. Anderson
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Patent number: 9339760Abstract: Methods, systems and apparatuses herein provide a unique and novel process to remove H2S from biogas. Methods, systems and apparatuses herein provide a unique and novel process to remove H2S from biogas with ease of operation and reduced operating and capital costs. Methods, systems and apparatuses herein provide a unique and novel process to remove H2S over CO2 from biogas.Type: GrantFiled: March 15, 2013Date of Patent: May 17, 2016Assignees: DVO, Inc., Washington State UniversityInventors: Nicholas Kennedy, Quan-Bao Zhao, Anping Jiang, Craig Frear, Stephen W. Dvorak
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Patent number: PP26735Abstract: A new variety of sweetpotato identified as ‘LA06-52’ is disclosed having disease resistance to Fusarium wilt, Rhizopus soft rot (intermediate), southern root-knot nematode, and Streptomyces soil rot, an orange flesh, copper skin and high yield characteristics.Type: GrantFiled: March 11, 2014Date of Patent: May 17, 2016Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College Through The LSU AgCenterInventors: Don R. Labonte, Arthur Q. Villordon, Tara P. Smith, Christopher A. Clark