Abstract: A separation sampling module for use within a bucket of a centrifuge for monitoring separation of a sample in a container includes a housing operable for supporting the container for containing the sample and removably positionable within the bucket of the centrifuge, at least one light source for illuminating the sample, at least one light detector for detecting light from the sample, and at least one of a power source and a connector operably connectable to a power source for use in powering the at least one light source. Light from the at least one light source passing through the sample defines a light path disposed in a direction across the direction of a centrifugal force when the separation sampling module is disposed in the bucket and rotated in the centrifuge.

Abstract: Compositions and methods for reducing the level of nornicotine and N?-nitrosonornicotine (NNN) in tobacco plants and plant parts thereof are provided. The compositions comprise isolated polynucleotides and polypeptides for a root-specific nicotine demethylases, CYP82E10, and variants thereof, that are involved in the metabolic conversion of nicotine to nornicotine in these plants. Compositions of the invention also include tobacco plants, or plant parts thereof, comprising a mutation in a gene encoding a CYP82E10 nicotine demethylase, wherein the mutation results in reduced expression or function of the CYP82E10 nicotine demethylase. Seed of these tobacco plants, or progeny thereof, and tobacco products prepared from the tobacco plants of the invention, or from plant parts or progeny thereof, are also provided. Methods for reducing the level of nornicotine, or reducing the rate of conversion of nicotine to nornicotine, in a tobacco plant, or plant part thereof are also provided.

Abstract: Embodiments of the present invention include apparatuses and methods for performing remote experiments in real-time. The method includes sending requests to perform remote experiments for a desired configuration to a first and second facility. The desired configuration may include a first and second configuration. The method includes running a first remote experiment in real-time at the first facility to obtain a first output variable. The first facility may include the first configuration with a first input variable. The method includes simultaneously running a second remote experiment in real-time at a second facility to obtain a second output variable. The second facility may include the second configuration with a second input variable. The first output variable may be set as the second input variable to mimic the desired configuration. The method includes obtaining experimental results of the desired configuration via the first and second input and output variables.

Abstract: Described herein are methods for diagnosing ovarian cancer. In particular, certain microRNAs are useful to the response to chemotherapy of ovarian cancer patients.

Abstract: Embodiments of hydrogels for electrochemical sensing, electrodes comprising the hydrogels, and methods of making and using the hydrogels are disclosed. The disclosed hydrogel electrodes comprise a cross-linked poly(acrylic acid-co-2-acrylamido-2-methyl-1-propanesulfonic acid (poly(AA-AMPS)) hydrogel and an electrical contact.

Abstract: Example devices and methods of MRI scanning are disclosed herein. In an example, an MRI scanning system may include a structure defining a bore within which a subject is to be positioned for scanning. The system may also include a magnet to generate a primary magnetic field within the bore parallel to a longitudinal axis of the bore, and a helical-antenna radio-frequency (RF) coil oriented along the longitudinal axis to surround the subject. In addition, the system may include an RF signal generator to drive the helical-antenna RF coil to generate a circularly polarized (CP) RF magnetic field perpendicular to the longitudinal axis, as well as an RF detector to detect a response signal generated by tissues of the subject in response to the CP RF magnetic field. Also included may be a computing system to create an image of the tissues of the subject based on the detected response signal.

Abstract: Systems, methods, and media for on-line boosting of a classifier are provided, comprising: receiving a training sample; for each of a plurality of features, determining a feature value for the training sample and the feature, using the feature value to update a histogram, and determining a threshold for a classifier of the feature; for each of the plurality of features, classifying the training sample using the threshold for the classifier of the feature and calculating an error associated with the classifier; selecting a plurality of best classifiers from the classifiers; and, for each of the plurality of best classifiers, assigning a voting weight to the one of the plurality of best classifiers.

Abstract: Embodiments for a tubular ceramic-carbonate dual-phase membrane and methods for manufacturing the tubular ceramic-carbonate dual-phase membrane are disclosed.

Abstract: Disclosed herein is a set of E. coli single-protein production (SPP) technologies with protein NMR (SPP-NMR) for (i) using isotope-enriched membrane proteins produced with the SPP system in screening detergent conditions suitable for purification and/or three-dimensional structure analysis without the requirement for protein purification, (ii) producing 2H, 13C, 15N enriched proteins suitable for high throughput and membrane protein NMR studies, and (iii) labeling with 13C-15N specific peptide bonds in proteins (referred to herein as SPP-PBL).

Abstract: Platinum nanocatalysts on multi-walled carbon nanotubes (MWCNTs) functionalized with citric acid (CA) are disclosed, along with methods for the synthesis thereof.

Abstract: Compounds of the formulae, (I), wherein each variable is as defined herein are provided which are useful in (i) diagnostic methods for detecting and/or identifying cells presenting PSMA; (2) compositions comprising a compound of the invention together with a pharmaceutically acceptable carrier, excipient, and/or diluent; (3) methods for inhibiting or treating prostrate cancer; and (4) methods for blocking or destabilizing neovasculature of a tumor.

Abstract: Methods of applying dicyclopropene compounds and compositions thereof to block ethylene receptors in plants are disclosed. Methods include applying to the plant an effective ethylene response-inhibiting amount of a dicyclopropene compound or composition thereof. Dicyclopropene compounds, enantiomers, stereoisomers or salts thereof are also provided.

Abstract: Provided are devices for bone tissue engineering, comprising a metal or metal-based composite member comprising an interior macroporous structure with porosity varying from 0-90% (v), the member comprising a surface region having a surface pore size, porosity, and composition designed to encourage cell growth and adhesion thereon, to provide a device engineered for a particular recipient subject. Engineered devices may further comprises a gradient of pore size, porosity, and material composition extending from the surface region throughout the interior of the device, wherein the gradient transition is continuous, discontinuous or seamless to promote cell in-growth.

Abstract: Methods are provided for modulating the activity of multimeric ubiquitin-protein E3 ligases including, but not limited to, E6AP ligase activities. The methods reduce the level of oligomer formation such as homotrimeric E6AP ligase to reduce the enzyme activity. Alternatively, agents are provided that can promote the association of the ligase monomers, thereby increasing the ligase activity. Accordingly, novel therapeutic strategies are provided that are useful for the treatment of pathologies resulting from mutations in the genes encoding the ligases and which adversely increase or decrease a ubiquitination reaction.

Abstract: The present invention relates to novel diacylglycerol acyltransferase genes and proteins, and methods of their use. In particular, the invention describes genes encoding proteins having diacylglycerol acetyltransferase activity, specifically for transferring an acetyl group to a diacylglycerol substrate to form acetyl-Triacylglycerols (ac-TAGS), for example, a 3-acetyl-1,2-diacyl-sn-glycerol. The present invention encompasses both native and recombinant wild-type forms of the transferase, as well as mutants and variant forms. The present invention also relates to methods of using novel diacylglycerol acyltransferase genes and proteins, including their expression in transgenic organisms at commercially viable levels, for increasing production of 3-acetyl-1,2-diacyl-sn-glycerols in plant oils and altering the composition of oils produced by microorganisms, such as yeast, by increasing ac-TAG production.

Abstract: A luminescent device including an emission layer having luminescent nanoclusters is provided. The luminescent nanoclusters can be phosphorescent metal halides. The luminescent device can emit IR, NIR, colored, or white light and be pumped electrically or optically. A method for manufacturing a luminescent device including an emission layer having luminescent nanoclusters is also provided.

Abstract: A linear hot-electron injection technique is provided for a non-volatile memory arrangement. The non-volatile memory is comprised of: a floating gate transistor; a capacitor with a first terminal electrically coupled to the gate node of the floating gate transistor; a current reference circuit electrically coupled to the source node of the floating gate transistor; and a feedback circuit electrically coupled between the source node of the floating gate transistor and a second terminal of the capacitor. The feedback circuit operates to adjust a voltage at the gate node of the floating gate transistor in accordance with a source-to-drain voltage across the floating gate transistor.

Abstract: Static synchronous compensator (STATCOM) systems and methods are disclosed. An example STATCOM system includes a reactive component configured for electrical connection to a power network. For example, the reactive component may be a capacitor bank. The system also includes an inductor electrically connected in series with the reactive component. Further, the system includes a converter electrically connected in series with the reactive component and the inductor. A method may include using the static synchronous compensator system to provide one of reactive power and active power to the power network.

Abstract: A system includes a shear member and an energy absorber. The shear member is configured to couple a seat portion to a base structure of a vehicle. The shear member is configured to sustain a first load without fracture and configured to inelastically deform under a second load. The second load is greater than the first load. The energy absorber is coupled to the seat portion and coupled to the base structure. The energy absorber is configured to absorb the energy following deformation of the shear member.

Abstract: The present invention relates to in situ formation of a single-layered electrochemical cell comprising a full tri-layer battery structure containing a discrete positive electrode, solid state electrolyte, and negative electrode from self-assembled nanocomposites. The single layered cell makes it possible to fabricate cells in three dimensions resulting in a very high energy density power source within very small and/or complex dimensions.