Patents Assigned to State University
  • Core-shell nanoparticles with multiple cores and a method for fabricating them
    Patent number: 9327314
    Abstract: The present invention is directed toward core-shell nanoparticles, each comprising a ligand-capped metal shell surrounding a plurality of discrete, nonconcentric, metal-containing cores. Methods of making and using these nanoparticles are also disclosed.
    Type: Grant
    Filed: November 19, 2012
    Date of Patent: May 3, 2016
    Assignee: The Research Foundation for the State University of New York
    Inventors: Chuan-Jian Zhong, Hye-Young Park
  • IN VITRO DETECTION OF PRIONS IN BLOOD
    Publication number: 20160116487
    Abstract: A method of screening a blood sample for the presence of prions. The method includes the steps of collecting the blood sample in heparin, contacting the sample with a solution comprising recombinant prion protein (rPrP) and Thioflavin T (ThT), and measuring the resulting ThT fluorescence in the sample. The method can further include the step of freezing and thawing the sample prior to contacting the sample with a solution comprising recombinant prion protein (rPrP) and Thioflavin T (ThT). The method can also include the step of precipitating the prions in sodium phosphotungstic acid (NaPTA) prior to contacting the sample with a solution comprising recombinant prion protein (rPrP) and Thioflavin T (ThT).
    Type: Application
    Filed: October 22, 2015
    Publication date: April 28, 2016
    Applicant: Colorado State University Research Foundation
    Inventors: Edward A. Hoover, Candace K. Mathiason
  • METHOD AND APPARATUS FOR ANALYZING DATA RELATED TO VEHICLE RANGE ESTIMATION
    Publication number: 20160114698
    Abstract: A method of analyzing data related to a driving range estimation of a vehicle includes collecting attribute data related to the driving range estimation of the vehicle, analyzing a correlation between the attribute data and a driving range of the vehicle, generating a vehicle driving range estimation model based on the analyzed correlation, and analyzing a sensitivity between the vehicle driving range estimation model and the attribute data.
    Type: Application
    Filed: October 27, 2015
    Publication date: April 28, 2016
    Applicants: NORTH CAROLINA STATE UNIVERSITY, SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Mo-Yuen Chow, Paul Barom Jeon, Habiballah Rahimi Eichi, Taejung Yeo
  • Myeloid derived suppressor cell inhibiting agents
    Patent number: 9320735
    Abstract: Myeloid derived suppressor cell (MDSC) inhibitory agents and vaccine and/or adjuvant enhancers are provided. Improved vaccine treatment regimens employing these agents are also provided. Cancer vaccines and methods for inhibiting tumor growth and cancer metastases are also presented. The myeloid derived suppressor cell (MDSC) inhibiting agents are described as bisphosphonates (such as liposomal clodronate) and CCR2 inhibitors and/or CCR2 antagonists. Methods for enhancing antibody titer levels in response to an antigen of interest are also provided.
    Type: Grant
    Filed: June 22, 2011
    Date of Patent: April 26, 2016
    Assignee: Colorado State University Research Foundation
    Inventors: Steven W. Dow, Angela J Henderson, Leah Mitchell
  • Separation apparatus and processes
    Patent number: 9321057
    Abstract: An apparatus may include a separator and/or a discharger. A separator may include a separator channel, an influent portion configured to allow the passage of a first fluid into a separator channel, an effluent portion disposed above an influent portion and/or a fluid-lift portion between an influent portion and an effluent portion. A discharger may be disposed below a fluid-lift portion and/or may include a portion external to a separator channel, which may include a downward angle relative to an effluent portion and/or may be configured to minimize the passage of a second fluid into a discharger as the second fluid buoyantly travels in a separator channel from an influent portion to an effluent portion. A second fluid may have a density that is less than the density of a first and/or may be configured to lift a first fluid to a fluid-lift portion.
    Type: Grant
    Filed: November 21, 2011
    Date of Patent: April 26, 2016
    Assignee: Savannah State University
    Inventors: Christopher Hintz, Amber Wilkinson
  • Tunable electro-optic liquid crystal lenses having resistive bridges and methods for forming the lenses
    Patent number: 9323113
    Abstract: Electro-optic lenses, including liquid crystals, wherein the power of the lenses can be modified by application of an electric field. In one embodiment, the liquid crystal-based lenses include ring electrodes having a resistive bridge located between adjacent electrodes, and in a preferred embodiment, input connections for several electrode rings are spaced on the lens. In a further embodiment, liquid crystal-based lenses are provided that can increase optical power through the use of phase resets, wherein in one embodiment, a lens includes ring electrodes on surfaces of the substrates on opposite sides of the liquid crystal cell such that a fixed phase term can be added to each set of electrodes that allows for phase change across each group of electrodes to be the same and also be matched with respect to a previous group.
    Type: Grant
    Filed: May 23, 2013
    Date of Patent: April 26, 2016
    Assignee: KENT STATE UNIVERSITY
    Inventors: Philip Bos, Douglas Bryant, Lei Shi, Bentley Wall
  • Nanoparticles and nanoparticle compositions
    Patent number: 9320713
    Abstract: The invention provides multivalent surface-crosslinked micelle (SCM) particles, crosslinked reverse micelle (CRM) particles, and methods of making and using them. The SCM particles can be used, for example, to inhibit a virus or bacteria from binding to a host cell. The inhibition can be used in therapy for the flu, cancer, or AIDS. The CRM particles can be used, for example, to prepare metal nanoparticles or metal alloy nanoparticles, or they can be used in catalytic reactions.
    Type: Grant
    Filed: June 26, 2014
    Date of Patent: April 26, 2016
    Assignee: Iowa State University Research Foundation, Inc.
    Inventor: Yan Zhao
  • Simultaneous saccharification and fermentation(SSF) of lignocellulosic biomass for single cell oil production by oleaginous microorganisms
    Patent number: 9322038
    Abstract: Methods for producing lipids from lignocellulosic biomass are provided. Sugars produced by pretreatment of lignocellulosic biomass are utilized by heterotrophic oleaginous fungi or yeast to increase their biomass and to produce lipids without prior detoxification of the pretreated biomass. After the fungi/yeast are cultured with the sugars, solid residues from the pretreated biomass are combined with the fungi/yeast under conditions which allow simultaneous 1) enzymatic degradation of cellulose and/or hemicellulose to produce sugars and 2) fermentation of the sugars for further increases in biomass and lipid production.
    Type: Grant
    Filed: July 6, 2012
    Date of Patent: April 26, 2016
    Assignee: Washington State University
    Inventors: Xiaochen Yu, Jijiao Zeng, Yubin Zheng, Mahesh Bule, Shulin Chen
  • Nanoferrite flakes
    Patent number: 9324484
    Abstract: A ferrite layer having a columnar structure is formed, and ferrite flakes are separated from the ferrite layer. The ferrite flakes include a metal oxide having a spinel cubic crystal structure with a stoichiometry represented by AB2O4, where A and B represent different lattice sites occupied by cationic species, and O represents oxygen in its own sublattice.
    Type: Grant
    Filed: February 6, 2014
    Date of Patent: April 26, 2016
    Assignee: Arizona Board of Regents for and on behalf of Arizona State University
    Inventors: Nicole M. Ray, William T. Petuskey
  • Branched nanostructures for battery electrodes
    Patent number: 9325014
    Abstract: The invention relates to electrochemical electrodes containing branched nanostructures having increased surface area and flexibility. These branched nanostructures allow for higher anode density, resulting in the creation of smaller, longer-lasting, more efficient batteries which require less area for the same charging capacity. Also disclosed are methods for creating said branched nanostructures and electrodes.
    Type: Grant
    Filed: August 23, 2011
    Date of Patent: April 26, 2016
    Assignee: THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK
    Inventors: Jae Ho Lee, Isaac Lund
  • Methods of and devices for capturing circulating tumor cells
    Patent number: 9322047
    Abstract: A device and methods are provided for efficient and quick capture of target cells through a main microchannel having capture elements immobilized thereon and manipulating a velocity profile of a sample as it passes through the main microchannel. The cell capture device may have a main microchannel with a depth slightly larger than the diameter of the target cells and a plurality of side microchannels. The side microchannels may have a depth smaller than the diameter of the target cells. The device and methods may be used for early cancer detection.
    Type: Grant
    Filed: October 19, 2012
    Date of Patent: April 26, 2016
    Assignee: BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
    Inventors: Taehyun Park, Daniel Sang-Won Park, Sudheer D Rani, Michael C Murphy, Dimitris E Nikitopoulos
  • Methods and systems for screening and treatment of infants demonstrating deficits in auditory processing
    Patent number: 9320458
    Abstract: The present invention provides a method and apparatus for screening infants at high risk for central auditory processing deficits and then remediating less efficient processing behaviorally using an adaptive training algorithm that gradually increases sensitivity to rapidly occurring stimuli streams.
    Type: Grant
    Filed: February 2, 2015
    Date of Patent: April 26, 2016
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: April A. Benasich, Teresa Realpe-Bonilla, Naseem Choudhury, Cynthia P. Roesler, Jason Nawyn
  • Nanoparticle composition, a device and a method thereof
    Patent number: 9324473
    Abstract: A nanoparticle composition, a device including the nanoparticle composition, and a method thereof are provided. The composition comprises nanoparticles such as Gold nanorods (NR) and electrically charged self-assembled molecular aggregates such as disodium chromoglycate (DSCG) in a common solvent such as water. The nanoparticles are assembled as, for example, side-by-side and end-to-end assemblies of nanorods, through a non-covalent interaction such as anisotropic electrostatic interaction with the electrically charged self-assembled molecular aggregates.
    Type: Grant
    Filed: August 25, 2009
    Date of Patent: April 26, 2016
    Assignee: KENT STATE UNIVERSITY
    Inventors: Oleg D. Lavrentovich, Heung-Shik Park
  • Synthesis of four coordinated gold complexes and their applications in light emitting devices thereof
    Patent number: 9324957
    Abstract: Synthesis of four coordinated gold complexes and their applications in light emitting devices thereof.
    Type: Grant
    Filed: May 2, 2011
    Date of Patent: April 26, 2016
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Jian Li, Eric Tumer
  • Compositions and methods for detecting and modulating cell death by a translation regulated gene expression system
    Patent number: 9322034
    Abstract: The technology relates to a nucleic acid expression cassette comprising a TR element encoding an mRNA molecule that is translated in stressed and/or dying cells, and a nucleotide sequence operably linked to the TR element, that is a first open reading frame (ORF) sequence and encodes a polypeptide or a fragment thereof and is co-translated with the TR element. The technology further relates to mammalian cells and a transgenic animal comprising such expression cassette. Further included are kits comprising the expression cassette, and methods for determining toxicity, and killing a target cell.
    Type: Grant
    Filed: August 7, 2008
    Date of Patent: April 26, 2016
    Assignee: Wayne State University
    Inventors: Leon Carlock, Maria Cypher
  • Expression systems and methods of producing spider silk proteins
    Patent number: 9321816
    Abstract: An expression system, including a host cell, a synthetic spider silk polypeptide-encoding nucleotide sequence, at least one synthetic tRNA molecule-encoding nucleotide sequence or a synthetic serine hydroxymethyl transferase (SHMT)-encoding nucleotide sequence.
    Type: Grant
    Filed: September 30, 2013
    Date of Patent: April 26, 2016
    Assignee: Utah State University
    Inventors: Randolph V. Lewis, Charles D. Miller, Asif Rahman, Cody Tramp, Michael Hinman
  • Topoisomerase inhibitors
    Patent number: 9321781
    Abstract: The invention provides compounds of formula I: (I) wherein A, B, W, Y, Z, R1, R3 and R4 have any of the meanings defined in the specification and their salts as well as additional compounds and their salts. The invention also provides pharmaceutical compositions comprising a compound of the invention, processes for preparing compounds of the invention, intermediates useful for preparing compounds of the invention, and therapeutic methods for treating cancer, a bacterial infection or a fungal infection using compounds of the invention.
    Type: Grant
    Filed: November 4, 2010
    Date of Patent: April 26, 2016
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Edmond J. Lavoie, Ajit K. Parhi
  • NEAR INFRARED LABEL AND METHODS OF USE THEREOF
    Publication number: 20160106867
    Abstract: The present invention provides compounds useful as novel near-infrared labels, compositions containing these compounds, and methods of using the near-infrared labels to identify targets in vitro, in situ and in vivo. The invention also provides small or large molecule conjugates between targeting agents and NIR labels, as well as methods and kits thereof, that can be used in diagnostics and treatment of diseases related to microbes in mammalian animals.
    Type: Application
    Filed: May 8, 2014
    Publication date: April 21, 2016
    Applicants: Rutgers, The State University of New Jersey, New Jersey Institute of Technology
    Inventors: Arkady Mustaev, David S. Perlin, Laura Wirpsza
  • Pedicle Screw Assembly and Dynamic Spinal Stabilization Devices Incorporating the Pedicle Screw Assembly
    Publication number: 20160106476
    Abstract: A dynamic spinal stabilization device for the treatment of high-grade spinal disorders is disclosed herein. The dynamic spinal stabilization device includes two or more screw assemblies, each of which include a pedicle screw and a head socket containing a curved internal track that limits the range of motion and center of rotation of the spinal segments stabilized using the device to the physiological levels of a nondegraded spinal segment.
    Type: Application
    Filed: December 21, 2015
    Publication date: April 21, 2016
    Applicant: Colorado State University Research Foundation
    Inventors: Christian M. Puttlitz, Benjamin C. Gadomski
  • Real-time small-signal stability assessment of power electronic-based components in contemporary power systems
    Patent number: 9316701
    Abstract: A novel method for real-time small-signal stability analysis for power electronic-based components in a power system. The method is based on impedance measurement techniques and Generalized Nyquist Criterion. The method is capable of real-time application. The method may be used to monitor a system in real-time by perturbing the system persistently and utilizing the system's responses to calculate source/load impedance in time-domain and based on d-q impedance measurement theory. Time-domain results may be transferred to frequency-domain results by taking advantage of a fast Fourier transform algorithm (or optionally discrete Fourier transformer for discrete systems) and monitoring the system's stability by obtaining a Nyquist contour and employing Generalized Nyquist Criterion or unit circle criterion.
    Type: Grant
    Filed: May 1, 2015
    Date of Patent: April 19, 2016
    Assignee: The Florida State University Research Foundation, Inc.
    Inventors: Mohamadamin Salmani, Chris S. Edrington