Patents Assigned to State University
  • Methods and compositions for determining the purity of chemically synthesized nucleic acids
    Patent number: 9273149
    Abstract: This application describes an antibody that specifically binds to a synthetic oligomer (e.g., an oligonucleotide or oligopeptide) having a organic protecting group covalently bound thereto, which antibody does not bind to that synthetic oligomer when the organic protecting group is not covalently bound thereto. Methods of making and using such antibodies are also disclosed, along with cells for making such antibodies and articles carrying immobilized oligomers that can be used in assay procedures with such antibodies.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: March 1, 2016
    Assignees: Veri-Q, Inc., North Carolina State University
    Inventors: Paul F. Agris, Christopher D. J. Pearce, Lloyd G. Mitchell
  • Use of genes and proteins for peptide production
    Patent number: 9273100
    Abstract: The present invention relates to compositions and methods comprising genes and peptides associated with cyclic peptides and cyclic peptide production in mushrooms. In particular, the present invention relates to using genes and proteins from Galerina species encoding peptides specifically relating to amatoxins in addition to proteins involved with processing cyclic peptide toxins. In a preferred embodiment, the present invention also relates to methods for making small peptides and small cyclic peptides including peptides similar to amanitin. Further, the present inventions relate to providing kits for making small peptides.
    Type: Grant
    Filed: January 31, 2012
    Date of Patent: March 1, 2016
    Assignee: Board of Trustees of Michigan State University
    Inventors: Heather E. Hallen-Adams, John S. Scott-Craig, Jonathan D. Walton, Hong Luo
  • Ginger metabolites and uses thereof
    Patent number: 9272994
    Abstract: The present application generally relates to the use of metabolites of ginger and analogs thereof for the treatment and prevention of diseases, including but not limited to, cancer.
    Type: Grant
    Filed: December 19, 2013
    Date of Patent: March 1, 2016
    Assignee: North Carolina A&T State University
    Inventors: Shengmin Sang, Huadong Chen, Yingdong Zhu
  • Method of inhibiting nonsense-mediated mRNA decay
    Patent number: 9271998
    Abstract: Provided are methods for treating a NAD comprising administering to a patient suffering from a NAD a composition comprising an eIF5A inhibitor compound in an amount effective to prevent intracellular hypusination of eIF5A, whereby gene expression of NMD-susceptible mRNA is increased.
    Type: Grant
    Filed: November 18, 2013
    Date of Patent: March 1, 2016
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Tsafi Pe'ery, Michael B. Mathews, Mainul Hoque, Hartmut M. Hanauske-Abel
  • Liquid-gas interface plasma device
    Patent number: 9272359
    Abstract: A plasma system for treating a workpiece is disclosed. The plasma system includes: a plasma device including an electrode formed from a metal alloy and a dielectric layer covering the electrode, the dielectric layer including a distal portion extending distally past a distal end of the electrode by a predetermined distance; a liquid source configured to supply a liquid to a workpiece; an ionizable media source coupled to the plasma device and configured to supply ionizable media thereto; and a power source coupled to the electrode and configured to ignite the ionizable media at the plasma device to form a plasma effluent in the presence of the liquid, whereby the plasma effluent reacts with the liquid to form at least one reactive species that interacts with the workpiece.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: March 1, 2016
    Assignee: Colorado State University Research Foundation
    Inventors: Il-Gyo Koo, George J. Collins
  • Polyols from biomass and polymeric products produced therefrom
    Patent number: 9273180
    Abstract: Polyol compositions containing methane linkages derived from amino acids. The polyols are obtained from the reaction of the carbonate with the cadres in the amino acids. Individual amino acids or mixtures of amino acids that are prepared from the hydrolysis of the proteins can be used.
    Type: Grant
    Filed: September 24, 2013
    Date of Patent: March 1, 2016
    Assignee: Board of Trustees of Michigan State University and Vahid Sendijarevice, joint ownership
    Inventors: Ramani Narayan, Daniel Graiver, Elodie Hablot, Vahid Sendijarevic, Siva Rama Krishna Chalasani
  • Composite structure and method of making a composite structure
    Patent number: 9273933
    Abstract: In accordance with the present teachings, a method of producing composite having a 3A Q3D reinforcement phase is disclosed. The method of producing the composite provides producing a three-dimensionally woven configuration where a first fiber from a first sheet of reinforcement phase is interwoven or mechanically linked with at least one of an adjacent second layer and then back into the first sheet. The linking fibers are passed between layers at an acute angle generally less than about 10 degrees. The method includes impregnating the woven construction with a curable polymer such as epoxy.
    Type: Grant
    Filed: May 20, 2013
    Date of Patent: March 1, 2016
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Dahsin Liu, Chun-Ying Lee, Chian-Fong Yen, Corey Anderson, Guojing Li
  • Insecticidal compositions and uses thereof
    Patent number: 9271504
    Abstract: The present invention provides compositions and methods for controlling plant pests. In particular, the present invention provides plant extracts with insecticidal activity.
    Type: Grant
    Filed: March 26, 2015
    Date of Patent: March 1, 2016
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Ayhan Gokce, Mark Whalon, Ibrahim Demirtas, Nezhun Goren
  • NMR RF probe coil exhibiting double resonance
    Patent number: 9274199
    Abstract: NMR probe coils designed to operate at two different frequencies, producing a strong and homogenous magnetic field at both the frequencies. This single coil, placed close to the sample, provides a method to optimize the NMR detection sensitivity of two different channels. In addition, the present invention describes a coil that generates a magnetic field that is parallel to the substrate of the coil as opposed to perpendicular as seen in the prior art. The present invention isolates coils from each other even when placed in close proximity to each other. A method to reduce the presence of electric field within the sample region is also considered. Further, the invention describes a method to adjust the radio-frequency tuning and coupling of the NMR probe coils.
    Type: Grant
    Filed: July 10, 2014
    Date of Patent: March 1, 2016
    Assignees: The Florida State University Research Foundation, Inc, University of Florida Research Foundation, Incorporated
    Inventors: William W. Brey, Arthur S. Edison, Vijaykumar Ramaswamy, Jerris Hooker
  • Voltage profile based fault location identification system and method of use
    Patent number: 9274161
    Abstract: The present invention provides a method to ensure that distributed resources of a power distribution system remain connected to the circuitry of the power distribution system when a fault occurs at a distributed resource node to assist in identifying the location of the fault by continuing to inject current from the distributed resources into the distribution system. The system contains multiple power electronics based converters which convert the local direct current (DC) distributed sources (DRs) to the alternating current (AC) of the grid. The converters also provide the capability of limiting the current in the system when a fault occurs. The converters also protect the power distribution system equipment against high fault currents.
    Type: Grant
    Filed: January 28, 2014
    Date of Patent: March 1, 2016
    Assignee: The Florida State University Research Foundation, Inc.
    Inventors: Passinam Tatcho, Mischa Steurer, Hui Li
  • Graft copolymer polyelectrolyte complexes for drug delivery
    Patent number: 9271933
    Abstract: Graft copolymer polyelectrolyte complexes are disclosed for the efficient delivery of anionic, cationic or polyelectrolyte therapeutic agents into biological cells, and for maintaining the biological activity of these molecules while in serum and other aqueous environments are provided. Such complexes comprise (1) an anionic graft copolymer containing an anionic polymer backbone, with pendent carboxylic acid groups and pendant chains containing amphipathic or hydrophilic polymers covalently bonded to a portion of the pendant carboxylic acid groups, (2) one or more anionic, cationic or polyelectrolyte therapeutic agents, and (3) optionally a liposome optionally containing an additional therapeutic agent. Also disclosed are functional nanoparticles containing the complexes.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: March 1, 2016
    Assignees: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, US ARMY, SECRETARY OF THE ARMY
    Inventors: David Devore, Charles Roth
  • Systems and devices for molecule sensing and method of manufacturing thereof
    Patent number: 9274430
    Abstract: Embodiments of the disclosure are directed to a device for molecule sensing. In some embodiments, the device includes a first electrode separated from a second electrode by a dielectric layer. The first electrode comprises a large area electrode and the second electrode comprises a small area electrode. At least one opening (e.g., trench) cut or otherwise created into the dielectric layer exposes a tunnel junction therebetween whereby target molecules in solution can bind across the tunnel junction.
    Type: Grant
    Filed: October 10, 2013
    Date of Patent: March 1, 2016
    Assignee: ARIZONA BOARD OF REGENTS on behalf of ARIZONA STATE UNIVERSITY
    Inventors: Brett Gyarfas, Stuart Lindsay, Pei Pang
  • Product and processes from an integrated forest biorefinery
    Patent number: 9273431
    Abstract: An omnibus process of pulping and bleaching lignocellulosic materials in which a charge of a lignocellulosic material is biopulped and/or water extracted prior to pulping and bleaching. The lignocellulosic material may be mechanically pulped and bleached in the presence of an enzyme that breaks lignin-carbohydrate complexes. The aqueous extract in embodiments including a water extract step is separated into acetic acid and hemicellulose sugar aqueous solutions.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: March 1, 2016
    Assignee: The Research Foundation for The State University of New York
    Inventors: Thomas E. Amidon, Raymond Francis, Gary M. Scott, Jeremy Bartholomew, Bandaru V. Ramarao, Christopher D. Wood
  • MULTISTAGE DELIVERY OF ACTIVE AGENTS
    Publication number: 20160051481
    Abstract: Multistage delivery vehicles are disclosed which include a first stage particle and a second stage particle. The first stage particle is a micro or nanoparticle that contains the second stage particle. The second stage particle includes an active agent, such as a therapeutic agent or an imaging agent. The multistage delivery vehicle allows sequential overcoming or bypassing of biological barriers. The multistage delivery vehicle is administered as a part of a composition that includes a plurality of the vehicles. Methods of making the multistage delivery vehicles are also provided.
    Type: Application
    Filed: May 29, 2015
    Publication date: February 25, 2016
    Applicants: Board of Regents of the University of Texas System, The Ohio State University Research Foundation
    Inventors: Mauro Ferrari, Ennio Tasciotti, Jason Sakamoto
  • CONTINUOUS LOCAL SLOW-RELEASE OF THERAPEUTICS FOR HEAD AND NECK PROBLEMS AND UPPER AERODIGESTIVE DISORDERS
    Publication number: 20160051492
    Abstract: The invention features formulations for the local delivery of therapeutically effective doses of curcumin to treat head and neck disorders and upper aerodigestive disorders. Also disclosed are use of the formulations for delivery of other phytochemicals, or the combination of phytochemicals for the treatment of said disorders. Furthermore, these formulations can be used to deliver the recommended daily allowance of vitamins and/or minerals to children or adults.
    Type: Application
    Filed: July 10, 2015
    Publication date: February 25, 2016
    Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Cherie Ann NATHAN, James Douglas BOURDREAUX
  • FOUR BAR APPARATUS AND METHOD FOR LIFTING, LOWERING, EXERCISE AND SELF-PROPELLED TRANSIT
    Publication number: 20160051427
    Abstract: Disclosed is a four bar apparatus and method for lifting, lowering, providing exercise and facilitating self-propelled transit. The apparatus includes an actuator and interconnected four-bar lifting mechanism, which includes a crank, a coupler, a rocker, and a frame. Each of the crank, coupler, rocker and frame are rotatably interconnected, and operation of the actuator moves a lift point of the coupler, with the lift point connectable to a vest-type garment or belt worn by a user of the apparatus, with the lift point following a J shape path or an S shape path to lift the user from a shoulder or hip area, respectively.
    Type: Application
    Filed: April 21, 2014
    Publication date: February 25, 2016
    Applicant: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: Anurag PURWAR, Bipin BIRARI
  • Multi-bandgap semiconductor structures and methods for using them
    Patent number: 9267076
    Abstract: Described herein are multi-segmented nanowires, nanosheets and nanobelts, and devices and methods using them for the generation of multicolor and white light.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: February 23, 2016
    Assignee: ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Cun-Zheng Ning, Zhicheng Liu, Leijun Yin, Fan Fan, Hao Ning, Sunay Turkdogan, Patricia L. Nichols
  • Precursors and transport methods for hydrothermal liquid phase sintering (HLPS)
    Patent number: 9266147
    Abstract: A method of producing a monolithic ceramic body from a porous matrix includes providing a porous matrix having interstitial spaces, providing an infiltrating medium comprising a solvent and at least one reactive species, and infiltrating at least a portion of the interstitial space of the porous matrix with the infiltrating medium. The solvent is an inert medium that is not chemically reactive with the porous matrix, and is in a liquid phase when in the portion of the interstitial space of the porous matrix. The infiltrating medium is mechanically convected through the porous matrix. The at least one reactive species, when in a portion of the interstitial space of the porous matrix, reacts with a portion of the porous matrix to form a product, and the product fills at least a portion of the interstitial space.
    Type: Grant
    Filed: September 30, 2013
    Date of Patent: February 23, 2016
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Richard E. Riman, Vahit Atakan, John P. Kuppler, Kenneth M. Smith
  • Extended active disturbance rejection controller
    Patent number: 9268315
    Abstract: Multiple designs, systems, methods and processes for controlling a system or plant using an extended active disturbance rejection control (ADRC) based controller are presented. The extended ADRC controller accepts sensor information from the plant. The sensor information is used in conjunction with an extended state observer in combination with a predictor that estimates and predicts the current state of the plant and a co-joined estimate of the system disturbances and system dynamics. The extended state observer estimates and predictions are used in conjunction with a control law that generates an input to the system based in part on the extended state observer estimates and predictions as well as a desired trajectory for the plant to follow.
    Type: Grant
    Filed: December 5, 2013
    Date of Patent: February 23, 2016
    Assignee: CLEVELAND STATE UNIVERSITY
    Inventors: Zhiqiang Gao, Gang Tian
  • System and method for treatment of biofilms
    Patent number: 9269544
    Abstract: A plasma system is disclosed. The system includes a plasma device including an inner electrode and an outer electrode coaxially disposed around the inner electrode, wherein at least one of the inner electrode and the outer electrode is temperature controlled; an ionizable media source coupled to the plasma device and configured to supply ionizable media thereto; and a power source coupled to the inner and outer electrodes and configured to ignite the ionizable media at the plasma device to form a plasma effluent.
    Type: Grant
    Filed: January 15, 2014
    Date of Patent: February 23, 2016
    Assignee: COLORADO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Il-Gyo Koo, Myeong Yeol Choi, Doreene Hyatt, Amber Zagrodzki, Dean A. Hendrickson, George J. Collins