Abstract: Methods for constructing tyrosine-derived biotinylated polymers. Biotinylated polymers and polymer scaffolds constructed with the biotinylated polymers are also disclosed.
Type:
Grant
Filed:
January 17, 2012
Date of Patent:
February 24, 2015
Assignee:
Rutgers, The State University of New Jersey
Inventors:
Jared S. Bushman, Jenny E. Raynor, Joachim B. Kohn
Abstract: A method is provided for authenticating an entity having a plurality of keys in a digital form residing on a claimant computing device. The method comprises: generating a first code word by applying a hash function to a first key residing on the claimant computing device; encoding the first code word into an array of bits having a Bloom filter format; generating a second code word by applying a hash function to a second key residing on the claimant computing device; encoding the second code word into the array of bits; and broadcasting an authentication message having the array of bits therein from the claimant computing device.
Type:
Grant
Filed:
March 12, 2008
Date of Patent:
February 24, 2015
Assignee:
Board of Trustees of Michigan State University
Abstract: The present invention provides an electro-optical device comprising a cell of polymer-stabilized blue phase (PSBP) liquid crystal under an electrical field and a method of controlling the reflection and transmission of an incident electromagnetic radiation such as visible light, by way of controlling the electrical field. The invention exhibits merits such as cost-effectiveness; simpler manufacturability due to the removal of requirements of polarizer and color filter; and fast switching, among others.
Abstract: Described herein are truncated EGF receptor polypeptides, nucleic acids encoding them, and methods of using them to help select a method of treatment for an EGFR-related cancer, to predict clinical outcome, and to detect micrometastases or minimal residual disease. High EGFR expression and phosphorylated EGFR predicts poor survival in head and neck cancer patients, but does not correlate with advanced stage disease. In our studies, we determined that clinical biological correlates are likely to be more accurate when different aspects of EGFR are evaluated in combination. We analyzed EGFR phosphorylation, expression and mutations in 60 primary head and neck tumors. We not only found that head and neck tumors with either truncated or activated EGFR tend to have higher tumor and nodal stage, but also discovered three EGFR truncations.
Type:
Grant
Filed:
May 5, 2011
Date of Patent:
February 24, 2015
Assignee:
The Research Foundation for the State University of New York
Abstract: The present invention provides a device for analyzing the composition of a heteropolymer comprising a carbon nanotube through which the heteropolymer is driven by electrophoresis. The carbon nanotube also serves as one electrode in a reading circuit. One end of the carbon nanotube is held in close proximity to a second electrode, and each end of the carbon nanotube is functionalized with flexibly-tethered chemical-recognition moieties, such that one will bind one site on the emerging polymer, and the second will bind another site in close proximity, generating an electrical signal between the two electrodes when the circuit is completed by the process of chemical recognition.
Type:
Grant
Filed:
March 18, 2009
Date of Patent:
February 24, 2015
Assignees:
Arizona Board of Regents, a body corporate of the State of Arizona Acting for and on behalf of Arizona State University, The Trustees of Columbia University in the City of New York
Inventors:
Colin Nuckolls, Jinyao Tang, Stuart Lindsay, Jin He, Peiming Zhang, Kevin Reinhart
Abstract: Innovative graft polymers designed for the efficient delivery of antisense molecules into biological cells and for maintaining the biological activity of these molecules while in serum and other aqueous environments are provided. Such polymers may comprise an anionic graft polymer comprising an anionic polymer backbone with pendant carboxylic acid groups and pendant chains comprising amphipathic or hydrophilic polymers covalently bonded to a portion of said pendant carboxylic acid groups. Antisense molecule delivery vectors comprising such polymers in combination with cationic agents for delivery of antisense molecules are also disclosed.
Type:
Grant
Filed:
November 26, 2008
Date of Patent:
February 24, 2015
Assignee:
Rutgers, The State University of New Jersey
Abstract: A method is provided for extraction of chemical compounds from an organism having a cell wall that includes adding nanomaterials, which may be metallic nanofibers such as silver nanofibers, to the organism.
Type:
Grant
Filed:
October 19, 2012
Date of Patent:
February 24, 2015
Assignee:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Inventors:
Maria Teresa Gutierrez-Wing, Kelly Ann Rusch
Abstract: Thiazolidinedione compounds and pharmaceutically acceptable salts thereof are described. The compounds can be used in methods of treating cancer in a subject by administering to the subject a therapeutically effective amount of the compound. The compounds can also be used in methods of inhibiting glucose uptake in a cell by contacting the cell with the compound.
Type:
Application
Filed:
March 28, 2013
Publication date:
February 19, 2015
Applicant:
The Ohio State University Research Foundation
Inventors:
Ching-Shih Chen, Dasheng Wang, Samuel K. Kulp
Abstract: For a hot carrier injection tolerant network on chip (NoC) router architecture, a coupling module modifies couplings of connecting wires to input buffer data bits in an NoC data channel. A connection module modifies connection points of an input buffer to the connecting wires.
Type:
Application
Filed:
October 17, 2013
Publication date:
February 19, 2015
Applicant:
UTAH STATE UNIVERSITY
Inventors:
Dean Michael Ancajas, Koushik Chakraborty, Sanghamitra Roy
Abstract: Buddleja ‘Blue Chip Jr’ is a new and distinct variety of butterfly bush that has the following unique combination of desirable features that are outstanding in a new variety. 1. ‘Blue Chip Jr’ has low vigor resulting in very dwarf stature. 2. ‘Blue Chip Jr’ is asexually propagated using softwood or semi-hardwood cuttings. 3. ‘Blue Chip Jr’ demonstrates a dense, spreading growth habit. 4. ‘Blue Chip Jr’ is lacking male flower parts (anthers), resulting in male (pollen) sterility. 5. ‘Blue Chip Jr’ produces female structures that are essentially sterile, resulting in lack of seed formation. 6. ‘Blue Chip Jr’ has purple-violet flower color.
Abstract: The invention relates to the over-expression of a transcription factor selected from the group consisting of MYB46, HAM1, HAM2, MYB112, WRKY11, ERF6, and any combination thereof in a plant, which can modulate and thereby modulating the cellulose content of the plant.
Type:
Application
Filed:
February 26, 2013
Publication date:
February 19, 2015
Applicant:
Board of Trustees of Michigan State University
Inventors:
Kyung-Hwan Han, Jae-Heung Ko, Won-Chan Kim, Joo-Yeol Kim
Abstract: For dynamic memory relocation, a tracking module tracks accesses to a plurality of memory devices. Each of the plurality of memory devices is in communication with one memory controller of a plurality of memory controllers embedded in a computing device comprising a plurality of nodes. A migration module migrates first data from a first memory device in communication with a first memory controller to a second memory device in communication with a second memory controller.
Type:
Application
Filed:
October 17, 2013
Publication date:
February 19, 2015
Applicant:
UTAH STATE UNIVERSITY
Inventors:
Dean Michael Ancajas, Koushik Chakraborty, Sanghamitra Roy
Abstract: An electric power system or power grid is optimized using a computer-implemented tool the represents in computer memory the optimization function and at least one constraint, which the processor operates upon using a linear programming solver algorithm. The constraints are represented in memory as data structures that include both real and reactive power terms, corresponding to at least one of a power flow model and a transmission line model. The transmission line model is represented using a piecewise linear representation. The power flow model may also include for each node in the power system a real power loss term representing transmission line loss allocated to that node.
Type:
Application
Filed:
August 13, 2014
Publication date:
February 19, 2015
Applicant:
Board of Trustees of Michigan State University
Abstract: The disclosure generally relates to the use of a bio-barcode (BBC) method for capture and demonstrates hybridization co-polymerization amplification readout of the BBC as a method of rapid detection of single stranded DNA output with an increased sensitivity for the initial target input to the BBC assay. The BBC assay reporter ssDNA can be modified for rapid readout. Two ssDNA molecules are designed to co-polymerize and then continually hybridize into double stranded DNA. The double stranded DNA can be optically and/or electrically detected. Kits related to the two ssDNA molecules and the BBC assay also are disclosed.
Type:
Application
Filed:
July 18, 2011
Publication date:
February 19, 2015
Applicant:
BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
Inventors:
Evangelyn C. Alocilja, Michael J. Anderson
Abstract: Buddleja ‘Pink Micro Chip’ is a new and distinct variety of butterfly bush that has the following unique combination of desirable features that are outstanding in a new variety. 1. ‘Pink Micro Chip’ has low vigor resulting in very dwarf stature. 2. ‘Pink Micro Chip’ is asexually propagated using softwood or semi-hardwood cuttings. 3. ‘Pink Micro Chip’ demonstrates a dense, spreading growth habit. 4. ‘Pink Micro Chip’ is lacking male flower parts (anthers), resulting in male (pollen) sterility. 5. “Pink Micro Chip’ produces female structures that are essentially sterile, resulting in lack of seed formation. 6. ‘Pink Micro Chip’ has red-purple flower color.
Abstract: A switching power converter includes a converter input configured to receive a first electrical signal, and a converter output configured to supply a second electrical signal at a desired voltage. The switching power also converter includes a control circuit for controlling one or more switches to produce the desired voltage. The control circuit is configured to control the one or more switches using one of pulse-frequency modulation and pulse-width modulation, such that an oscillating signal is generated using a combination of random frequency-hopping and random phase-chopping.
Type:
Application
Filed:
October 30, 2014
Publication date:
February 19, 2015
Applicant:
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
Abstract: This disclosure describes the molecular cloning of a pactamycin biosynthetic gene cluster from Streptomyces pactum ATCC 27456, characterization of individual genes in the gene cluster and the proteins encoded thereby as well as uses thereof. The pactamycin gene cluster is located within an 86.35 kilobases genetic locus and includes 53 open reading frames, 26 of which are considered to be the core cluster directly involved in the biosynthesis of pactamycin. The present disclosure also relates to the use of the pactamycin biosynthetic genes located within the identified gene cluster for drug design and development purposes, including the development of pactamycin analogs that are more efficacious and less toxic. Also provided are drugs and antibiotics so produced, as well as methods of their use.
Type:
Grant
Filed:
April 18, 2008
Date of Patent:
February 17, 2015
Assignee:
State of Oregon Acting by and Through the State Board of Higher Education on Behalf of Oregon State University
Abstract: Systems and methods for depositing complex thin-film alloys on substrates are provided. In particular, systems and methods for the deposition of thin-film Cd1-xMxTe ternary alloys on substrates using a stacked-source sublimation system are provided, where M is a metal such as Mg, Zn, Mn, and Cu.
Type:
Grant
Filed:
April 7, 2014
Date of Patent:
February 17, 2015
Assignee:
Colorado State University Research Foundation
Inventors:
Walajabad S. Sampath, Pavel S. Kobyakov, Kevin E. Walters, Davis R. Hemenway
Abstract: A new variety of sweetpotato, identified as ‘LA04-175’, is disclosed having disease resistance to both fusarium wilt, Streptomyces soil rot, and southern root-knot nematode; an orange flesh and red skin, and high yield characteristics.
Type:
Grant
Filed:
April 23, 2013
Date of Patent:
February 24, 2015
Assignee:
Board of Supervisors of Louisiana State University and A&M College Through The LSU Ag Center
Inventors:
Don R. Labonte, Arthur Q. Villordon, Tara Parker Smith, Christopher A. Clark