Patents Assigned to State University
  • BIOCOMPATIBLE GRAPHENE SENSOR
    Publication number: 20150038378
    Abstract: A graphene biosensor is formed on an electrically insulating substrate with a single-layer graphene sheet arranged between two metallic electrodes. The graphene sheet is in electrical contact with the metallic electrodes. The graphene sheet has perforations creating edges in the graphene sheet. The perforations may be holes on a micrometer scale or in a nanometer scale. The biosensor can be configured as an ISFET. The graphene sheet may comprise affinity probes immobilized on the edges for attaching specific molecules to the graphene sheet. Several graphene sheets may be arranged in a microarray with different affinity probes on different graphene sheets. The sensor may also be arranged on the distal end of a catheter for in situ measurements in a body vessel.
    Type: Application
    Filed: February 16, 2012
    Publication date: February 5, 2015
    Applicant: Wayne State University
    Inventors: Mark Ming-Cheng Cheng, Zhixian Zhou
  • BIMETAL CATALYSTS
    Publication number: 20150038751
    Abstract: The present disclosure discloses bimetal catalysts.
    Type: Application
    Filed: March 28, 2013
    Publication date: February 5, 2015
    Applicant: Wayne State University
    Inventors: K.Y. Simon Ng, Steve O. Salley, Huali Wang
  • PLANTS WITH ENHANCED TOLERANCE TO MULTIPLE ABIOTIC STRESSES
    Publication number: 20150040272
    Abstract: The present disclosure describes genetically-modified plants having enhanced tolerance to multiple abiotic stressors, such as extreme temperatures (heat or cold) and/or drought. Abiotic stress tolerance is enhanced by ectopic expression of a heterologous glutaredoxin. Abiotic stress tolerance (particularly drought) is also enhanced by inhibited function, activity, or expression of an endogenous glutaredoxin. Methods of producing such genetically-modified plants are also disclosed.
    Type: Application
    Filed: August 31, 2012
    Publication date: February 5, 2015
    Applicants: BAYLOR COLLEGE OF MEDICINE, KANSAS STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Sunghun Park, Frank White, Jungeun Park, Kendal Hirschi, Ning-Hui Cheng
  • Transcription Factor Inhibitors and Related Compositions, Formulations and Methods
    Publication number: 20150038443
    Abstract: The present invention provides small molecules useful to affect cancer cells, along with related methods. The present compounds, formulations, kits and methods are useful for a variety of research, diagnostic and therapeutic purposes. STAT3 inhibitors, particularly LLL12, are disclosed. The STAT3 inhibitors are useful to treat breast cancer in general and breast cancer initiating cells in particular.
    Type: Application
    Filed: October 16, 2014
    Publication date: February 5, 2015
    Applicants: NATIONWIDE CHILDREN'S HOSPITAL, INC., THE OHIO STATE UNIVERSITY
    Inventors: Pui-Kai Li, Chenglong Li, Jiayuh Lin
  • Methods of hydrolyzing pretreated densified biomass particulates and systems related thereto
    Patent number: 8945245
    Abstract: A method is provided in which pretreated and densified cellulosic biomass particulates can be hydrolyzed at a high solids loading rate as compared with the solids loading rate of loose hydrolysable cellulosic biomass fibers. The resulting high concentration sugar-containing stream can be easily converted to biofuels or an entire suite of other useful bioproducts.
    Type: Grant
    Filed: April 27, 2012
    Date of Patent: February 3, 2015
    Assignees: The Michigan Biotechnology Institute, Board of Trustees of Michigan State University
    Inventors: Bryan Bals, Farzaneh Teymouri, Tim Campbell, Bruce Dale
  • Light therapy treatment
    Patent number: 8945196
    Abstract: An exemplary method includes selecting at least one light source configured to generate light at a particular wavelength and applying the light to tissue following an ischemic event. Applying the light to the tissue inhibits cytochrome c oxidase activity. Another exemplary method includes selecting at least one light source configured to generate light at a particular wavelength and applying the light to tissue following an ischemic event and prior to either reoxygenation of the tissue or clinical intervention to reduce cell damage. An exemplary light therapy device includes at least one light source configured to generate light having a wavelength of at least one of approximately 730-770 nm, 850-890 nm, 880-920 nm, and 930-970 nm.
    Type: Grant
    Filed: April 30, 2010
    Date of Patent: February 3, 2015
    Assignee: Wayne State University
    Inventors: Maik Huttemann, Icksoo Lee, John Kamholz, Lawrence Grossman, Karin Przyklenk, Thomas Sanderson
  • Synthesis of four coordinated platinum complexes and their applications in light emitting devices thereof
    Patent number: 8946417
    Abstract: Platinum complexes that exhibit photoabsorption and photoemission, methods of making such complexes, and applications thereof are disclosed, including optical devices comprising the complexes.
    Type: Grant
    Filed: April 6, 2010
    Date of Patent: February 3, 2015
    Assignee: Arizona Board Of Regents Acting For And On Behalf Of Arizona State University
    Inventors: Li Jian, Zixing Wang, Eric Turner
  • Star polymer nanoshells and methods of preparation thereof
    Patent number: 8945513
    Abstract: A nanoshell is disclosed, comprising a star polymer occlusion complex comprising i) an amphiphilic unimolecular star polymer having a crosslinked core covalently linked to 6 or more independent polymer arms, and ii) a cargo material occluded in the star polymer; and a shell comprising an inorganic material in contact with a peripheral surface of the star polymer occlusion complex.
    Type: Grant
    Filed: March 18, 2011
    Date of Patent: February 3, 2015
    Assignees: International Business Machines Corporation, San Jose State University Research Foundation
    Inventors: Victor Yee-Way Lee, Robert Dennis Miller, Joseph Sly, Melia Tjio
  • Interspinous spacer devices for dynamic stabilization of degraded spinal segments
    Patent number: 8945185
    Abstract: An interspinous spacer device for the treatment of high-grade spinal disorders is disclosed herein. The interspinous spacer device includes a sliding rod and a base that contains a curved internal track that limits the range of motion and center of rotation of the spinal segments stabilized using the device to the physiological levels of a nondegraded spinal segment.
    Type: Grant
    Filed: September 2, 2011
    Date of Patent: February 3, 2015
    Assignee: Colorado State University Research Foundation
    Inventors: Christian M. Puttlitz, Benjamin C. Gadomski
  • Formulations comprising extracts from primitive plant species (mosses, ferns and lichens) to treat and prevent cancers
    Patent number: 8945635
    Abstract: Disclosed are extracts prepared from primitive plants and fungi that have anti-cancer properties. The extracts are prepared by pulverizing the biological matter in a diluent. The extract can be administered to an individual or animal to kill cancer cells, prevent growth of cancer cells and teat cancer. The extracts may be used in combination with other therapeutic protocols.
    Type: Grant
    Filed: August 12, 2013
    Date of Patent: February 3, 2015
    Assignee: Southern Connecticut State University
    Inventor: Sarah Crawford
  • Optofluidic tweezers
    Patent number: 8944084
    Abstract: In a method of moving droplets, local heat is applied to a surface portion of a droplet for an amount of time sufficient to create a Marangoni flow in the droplet. Droplets are suspended in an emulsion in a carrier liquid on a substrate. A laser beam is used to move one of the droplets. the droplet consists of a first substance and a carrier liquid consists of a second substance that is not mixable with the first substance. The droplet is placed in the carrier liquid, and the mixture is emulsified. The emulsified mixture is placed on a substrate. Then the local heat is applied to the surface of the droplet. The first substance may include oil and the second substance may include water.
    Type: Grant
    Filed: June 4, 2012
    Date of Patent: February 3, 2015
    Assignee: Wayne State University
    Inventors: Amar Basu, Gopakumar Kamalakshakurup
  • Multiple petal deployable telescope
    Patent number: 8947777
    Abstract: An opto-mechanical deployable telescope includes a hub, at least one deployable multiple petal primary mirror mounted to the hub, a deployment assembly, and a deployment engine assembly. The deployment assembly is operable to move the at least one primary mirror between a stowed position and a deployed position. The deployment engine assembly is operable to power the deployment assembly using stored mechanical energy. The deployment assembly includes a kinematic or semi-kinematic interface between the hub and the at least one primary mirror to hold petals of the at least one primary mirror in alignment relative to each other in the deployed position.
    Type: Grant
    Filed: February 27, 2012
    Date of Patent: February 3, 2015
    Assignee: Utah State University Research Foundation
    Inventors: Trent Newswander, Blake Crowther, James Champagne, Adam Norris
  • Optical coherence tomography systems and methods
    Patent number: 8948846
    Abstract: In general, in one aspect, the invention features a method that includes using an optical coherence tomography system to acquire a plurality of frames of a sample where each frame includes optical information about the composition of the sample through a section of the sample. The method further includes averaging over two or more of the frames to provide an image of the section of the sample where successive frames of the two or more frames are acquired with a time lapse of 0.05-0.7 seconds. Embodiments of the method may have unique advantages for endoscopic subcellular imaging. For example, they can enable subcellular imaging with low-NA optics (e.g., NA=0.25 or less) while providing morphological imaging of the underlying tissue up to 0.6 mm without focal tracking.
    Type: Grant
    Filed: September 18, 2008
    Date of Patent: February 3, 2015
    Assignee: The Research Foundation of State University of New York
    Inventor: Yingtian Pan
  • Fast-cycling, conduction-cooled, quasi-isothermal, superconducting fault current limiter
    Patent number: 8948830
    Abstract: Fault Current Limiters (FCL) provide protection for upstream and/or downstream devices in electric power grids. Conventional FCL require the use of expensive conductors and liquid or gas cryogen handling. Disclosed embodiments describe FCL systems and devices that use lower cost superconductors, require no liquid cryogen, and are fast cycling. These improved FCL can sustain many sequential faults and require less time to clear faults while avoiding the use of liquid cryogen. Disclosed embodiments describe a FCL with a superconductor and cladding cooled to cryogenic temperatures; these are connected in parallel with a second resistor across two nodes in a circuit. According to disclosed embodiments, the resistance of the superconducting components and its sheath in the fault mode are sufficiently high to minimize energy deposition within the cryogenic system, minimizing recovery time.
    Type: Grant
    Filed: July 29, 2011
    Date of Patent: February 3, 2015
    Assignee: The Ohio State University
    Inventors: Michael Sumption, Edward Collings, Milan Majoros
  • Fluorescent excimer lamps
    Patent number: 8946993
    Abstract: Excimers are formed in a high pressure gas by applying a potential between a first electrode (14, 214) and a counter electrode (25, 226) so as to impose an electric field within the gas, or by introducing high energy electrons into the gas using an electron beam. A phosphor for converting the wavelength of radiation emitted from the formed excimers is disposed within the gas and outside a region (62, 162) where the excimers are expected to be formed, so as to avoid degradation of the phosphor.
    Type: Grant
    Filed: May 15, 2009
    Date of Patent: February 3, 2015
    Assignee: Rutgers, The State University
    Inventors: Daniel E. Murnick, Nazieh Mohammad Masoud, Richard Riman
  • QSOX1 as an anti-neoplastic drug target
    Patent number: 8946186
    Abstract: The present invention provides methods for tumor treatment by administering an inhibitor of quiescin sulfhydryl oxidase 1 (QSOX1), compositions comprising such inhibitors, and methods for identifying such inhibitors.
    Type: Grant
    Filed: March 20, 2013
    Date of Patent: February 3, 2015
    Assignee: Arizona Board of Regents, a Body Corporate of the State of Arizona Acting for and on Behalf of Arizona State University
    Inventors: Douglas Lake, Benjamin Katchman
  • Display bender and method of testing flexible display
    Patent number: 8943898
    Abstract: Some embodiments include an apparatus for testing flexible displays. The apparatus can include: (a) a first clamp configured to receive a first end of the flexible display; (b) a second clamp configured to receive a second end of the flexible display, wherein the second end of the flexible display is opposite the first end of the flexible display; and (c) a test column. Other embodiments and methods are disclosed herein.
    Type: Grant
    Filed: November 28, 2011
    Date of Patent: February 3, 2015
    Assignee: Arizona Board of Regents, a body corporate of the State Arizona, Acting for and on behalf of Arizona State University
    Inventors: Cynthia Bell, Terry L. Alford, Roy Stephen Rednour, Mark Richards
  • Materials and methods related to microRNA-21, mismatch repair, and colorectal cancer
    Patent number: 8946187
    Abstract: The present invention discloses the discovery that miR-21 targets and down-regulates the core mismatch repair (MMR) recognition protein complex hMSH2 and hMSH6. Anti-sense miR-21 is therefore proven as therapeutic herein. Therefore, compositions, kits, therapies and other methods, including methods of treatment/amelioration of symptoms, are disclosed in the present invention.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: February 3, 2015
    Assignee: The Ohio State University
    Inventors: Carlo M. Croce, Nicola Valeri
  • Hybrids of, and cultivars derived from the rice cultivar designated ‘CL151’
    Patent number: 8946528
    Abstract: Hybrids and derived cultivars of the rice cultivar designated ‘CL151’ are disclosed. The invention relates to hybrid rice seeds and plants produced by crossing the cultivar ‘CL151’ with another rice cultivar. The invention further relates to other derivatives of the rice cultivar ‘CL151.
    Type: Grant
    Filed: November 18, 2009
    Date of Patent: February 3, 2015
    Assignee: Board of Supervisors of Louisiana State University And Agricultural and Mechanical College
    Inventor: Steven D. Linscombe
  • Vanadium Compounds as Therapeutic Adjuncts for Cartilage Injury and Repair
    Publication number: 20150030653
    Abstract: A method for repairing an injury of cartilage in a patient by local administration of an organovanadium agent or use of an implantable device for delivery of an organovanadium agent. Implantable devices containing an organovanadium agent and methods of making these implantable devices are also disclosed.
    Type: Application
    Filed: July 6, 2012
    Publication date: January 29, 2015
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Sheldon S. Lin, David N. Paglia, James P. O'Connor, Aaron Wey, Joseph Benevenia, Virak Tan