Abstract: The herbicide-tolerant rice cultivar designated ‘PVL03’ and its hybrids and derivatives are disclosed.

Abstract: One or more techniques and/or systems are disclosed for a harvester vehicle that includes a crop processing system comprising at least an accumulator and a round module builder. The harvester vehicle has a feedback fusion system that operably provides crop processing data indicative of an estimated accumulator fill level to a crop feed rate control system. The feedback fusion system has a plurality of feedback devices that operably provide feedback signals including data indicative of two or more of: crop mass flow, module builder status, module size, and accumulator fill level. The feedback fusion system has a control module that operably receives the feedback signals and generates an accumulator fill level signal based at least upon two or more of the feedback signals. The accumulator fill level signal is indicative of the estimated fill level in the accumulator.

Abstract: A system includes a device that is disposed within an environment and is adapted to communicate over a radio frequency communication link. The system also includes a wireless access point disposed within the environment, including a wireless transceiver in communication with the device over a radio frequency communication link using a plurality of channels, and recording a channel state information data set for the radio frequency communication link. The system also includes a monitoring device including a memory storing a plurality of activity profiles, each of which includes an activity and a channel state information profile corresponding to the activity, and a processor receiving, from the wireless access point, the channel state information data set and determining, based on a comparison of the channel state information data set to the channel state information profile of each of the plurality of activity profiles, the activity of the person in the environment.

Abstract: Techniques are described for efficiently reducing the amount of total computation in convolutional neural networks (CNNs) without affecting the output result or classification accuracy. Computation redundancy in CNNs is reduced by exploiting the computing nature of the convolution and subsequent pooling (e.g., sub-sampling) operations. In some implementations, the input features may be divided into a group of precision values and the operation(s) may be cascaded. A maximum may be identified (e.g., by 90% probability) using a small number of bits in the input features, and the full-precision convolution may then be performed on the maximum input. Accordingly, the total number of bits used to perform the convolution is reduced without affecting the output features or the final classification accuracy.

Abstract: An apparatus to remove liquid from a ventilation system can include a housing, a first port extending into an interior volume of the housing and a second port extending toward the first tube, into the interior volume, separated from the first port by a gap that is at least 5 mm in length, such that ventilating fluid transfers from the first port to the second while secretions and condensate escape through the gap, to be trapped in the housing. The first port joins with a ventilator. The second port joins with an intubation tube coupled to a tracheostomy or endotracheal tube. An extraction port is in a floor of the housing so that accumulated liquids in the housing can drain downward and out the extraction port, while minimizing positive end expiratory pressure loss in the ventilation system, and without exposing caregivers to biological material in the drained liquid.

Abstract: A perfusion plate that can be combined with pillar plates containing cell layers is disclosed. The perfusion plate can have an inflow reservoir and an outflow reservoir connected by at least one channel, which fluidly connects the perfusion wells to the reservoirs for the flow of a fluid such as growth media. A perfusion plate can be part of an assembly containing a pillar plate, a lid, and a transparent bottom for visualizing cell growth in the perfusion wells. The perfusion-pillar plate assembly can facilitate perfusion-based tissue culture and tissue communication for high throughput, high-content, drug screening.

Abstract: Protein biomarkers may be used to rapidly and accurately diagnose stroke. Biomarkers may be utilized in a rapid and inexpensive test that could be used at the bedside or ambulatory setting to definitively indicate the presence or absence of stroke and its severity. Such a test would quickly stratify patients in need of immediate stroke treatment from those who are not having a stroke. The test may aid emergency personnel in the decision for the most appropriate treatment plan and treatment location, thereby minimizing morbidity and mortality of stroke patients.

Abstract: The disclosure relates to methods of forming a dihydrochalcone using electrocatalytic dehydrogenation. In particular, the disclosure relates to methods of forming a dihydrochalcone electrocatalytically hydrogenating (ECH) a reactant compound over a catalytic cathode in a reaction medium having a non-alkaline pH value, thereby forming a dihydrochalcone product; wherein the reactant compound has a structure according to Formula (I). The method can be used to prepare dihydrochalcone sweeteners, such as, for example, naringin dihydrochalcone and neohesperidin dihydrochalcone.

Abstract: Aspects of the disclosure relate to synthetic regulatory systems composed of a multifunctional Cas nuclease, at least two guide RNAs (gRNAs) configured to target distinct nucleotide sequences, and a multilayered regulatory control element comprising ribozyme-based safety switches providing spatial and temporal control over the synthetic circuit in vivo.

Abstract: Methods of increasing production, stability or activity of a target polypeptide are provided herein. The method includes increasing the level of an antioxidant in a cell comprising a polynucleotide encoding the target polypeptide. Also provided are cells and transgenic organisms produced using the methods described herein. Methods of treating a subject with a condition treatable by administration of the target polypeptide are also disclosed. Finally methods and compositions for transiently increasing antioxidants in plant cells are provided.

Abstract: Provided herein are treatments for reducing pain in dogs. The treatments generally comprise a combination of an opioid compound, such as methadone, and an azole compound, such as fluconazole. The treatments may further comprise an opioid abuse deterrent that advantageously inhibits opioid effects in humans while maintaining desirable analgesic effects in dogs. Additionally, the treatments provided herein avoid the undesirable side effects of prior art opioid treatments for dogs. The treatments may be administered as separate doses or in a single formulation product for improved compliance. The treatments have wide use potential in dogs from perioperative patients to inpatients and outpatients and may be used, for example, for sedation in minor procedures, analgesia, and decreasing temperature in canine patients.

Abstract: Quantifying nanobubbles in solution includes combining an indicator with a fluid comprising nanobubbles to yield a first solution, bursting the nanobubbles in the first solution to yield a second solution, and assessing a difference between the first solution and the second solution to yield a concentration of the nanobubbles in the first solution, a concentration of reactive oxygen species in the first solution or the second solution, or both.

Abstract: The present disclosure relates to consortia of bacteria strains and composition comprising one or more bacterial strains disclosed herein. These consortia of isolated bacteria cultures and compositions comprising said cultures, having greater activity than would be observed for the individual bacteria cultures and compositions. A composition of the disclosure may advantageously be used for enhancing the availability of soil phosphorus and other macronutrients and/or micronutrients to plants, and thereby enhancing their growth and yield.

Abstract: A vital sign monitoring system using an optical sensor is provided. The vital sign monitoring system, and related methods and devices described herein, is equipped with a camera or other optical sensor to remotely detect and measure one or more physiological parameters (e.g., vital signs) of a subject. For example, the vital sign monitoring system can detect, measure, and/or monitor heart rates and respiration rates from one or multiple subjects simultaneously using advanced signal processing techniques, including adaptive color beamforming to more accurately detect and measure the vital sign(s) of interest.

Abstract: A compression ratio (CR) adapter (CRA) for end-to-end data-driven compressive sensing (CS) reconstruction (EDCSR) frameworks is provided. EDCSR frameworks achieve state-of-the-art reconstruction performance in terms of reconstruction speed and accuracy for images and other signals. However, existing EDCSR frameworks cannot adapt to a variable CR. For applications that desire a variable CR, existing EDCSR frameworks must be trained from scratch at each CR, which is computationally costly and time-consuming. Embodiments described herein present a CRA framework that addresses the variable CR problem generally for existing and future EDCSR frameworks with no modification to given reconstruction models nor enormous additional rounds of training needed. The CRA exploits an initial reconstruction network to generate an initial estimate of reconstruction results based on a small portion of acquired image measurements.

Abstract: Rapid assessment of microcirculation in tissue to realize closed-loop systems is provided. Microcirculatory assessment systems according to embodiments described herein allow a user to assess changes in local blood flow in microvasculature in real-time using conventional electrical techniques. Some embodiments provide a closed-loop system that allows calibrated doses of electrical stimulation to be delivered in a deep brain stimulation (DBS) system depending on blood flow changes (in specific regions of the brain) being fed back to a controller. The approach described here is readily translatable with very minimal changes to existing hardware. Such closed-loop systems will improve the accuracy of electrode placement in DBS surgery and potentially reduce surgery time, optimize the delivery of electrical stimulation, increase battery life of implantable DBS systems, reduce post-surgical visits to medical practitioners and improve the quality of life of patients.

Abstract: Methods and compositions for detecting the presence of a pathogen are described. In particular, this document provides a method of detecting a pathogen-associated nucleic acid in a biological sample of a subject, where the method comprises using one or more unimolecular aptamer-based sensors comprising an aptamer-fluorophore complex and an amplification step to detect the pathogen-associated nucleic acid. Methods specific for detecting the presence of malaria and other mosquito-borne virus infections are also provided.

Abstract: The present invention concerns compositions comprising at least one niclosamide compound, such as niclosamide or a pharmaceutically acceptable salt thereof, and at least one permeability enhancer, such as glycerol or dimethylpalmityl-ammonio propanesulfonate (PPS), and their use of such compositions as niclosamide agents. Advantageously, the niclosamide compound is capable of being transported across a Caco-2 cell membrane by at least 150% relative to the amount capable of being transported across the Caco-2 cell membrane in the absence of the permeability enhancer. Compositions, including oral dosage forms, and methods for delivering niclosamide compounds, such as for treatment or prevention of human coronavirus infections, are also provided.

Abstract: Various examples are provided related to direct current circuit breakers and their control methods. In one example, among others, a hybrid direct current circuit breaker (DCCB) includes an ultrafast mechanical switch (UFMS) connected in series with a commutating switch (CS) or auxiliary circuit breaker (ACB); a main breaker (MB) including a series of ? semiconductor switching stages in parallel with the UFMS and CS or ACB; and control circuitry that can turn off individual switching stages in a defined order in response to opening contacts of the UFMS. The switching stages can be turned off based upon a dielectric strength across the contacts as they open. In another example, a method includes opening contacts of an UFMS connected in series with a CS or ACB; and turning off individual switching stages of a series of ? semiconductor switching stages connected across the UFMS and the CS or ACB.

Abstract: The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered RNA-targeting systems comprising a novel RNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA.