Patents Assigned to Synthesis (U.S.A.)
  • Patent number: 7561279
    Abstract: An optical measuring apparatus for comprising, in combination, a polarization type interferometer including a polarization type beam splitter in which a polarized beam of light is split into orthogonally polarized reference and test beams, an array of detectors arranged in a line for creating a plurality of phase shifting interferograms, and a scanning device for moving the object in a direction perpendicular to a long axis of the detectors.
    Type: Grant
    Filed: June 28, 2007
    Date of Patent: July 14, 2009
    Assignee: Engineering Synthesis Design, Inc.
    Inventors: Raymond Castonguay, Piotr Szwaykowski
  • Patent number: 7490718
    Abstract: A collapsible treasure box is disclosed and includes an enclosure including an enclosed inner layer and an enclosed outer layer formed of soft cloth, the outer layer being in covering relationship with the inner layer wherein top edges of the inner and the outer layers are stitched together, an enclosed upper frame member concealed by passing upper portions of the inner and outer layers through a bore of the frame member to wrap around a bottom of the frame member, and a lower container member having an open top, the container being enclosed by wrapping a lower portion of the outer layer therearound by stitching bottoms of the inner and the outer layers together. Turning a top of the treasure box until a top opening thereof is closed and folding inside of the treasure box toward outside thereof continuously will shape the treasure box as a bun.
    Type: Grant
    Filed: November 9, 2005
    Date of Patent: February 17, 2009
    Assignee: Synthesis Enterprise Co., Ltd.
    Inventor: Wendy Shen
  • Patent number: 7477078
    Abstract: Variable phase bit sampling implementations are disclosed which minimize requirements for downstream digital processing resynchronization in systems that incorporate adjustable bit phase sampling that utilize variable delay elements which can interrupt the clocking stream signal. A sampling device includes a sampling circuit operative to provide an output signal in response to a data signal, where the sampling circuit includes a data input and a clock input. A variable delay circuit provides an adjustable trigger signal to the clock input in response to a first delay control signal. A fixed delay circuit delays the output signal by a predetermined amount of time in response to at least one delay control signal.
    Type: Grant
    Filed: January 19, 2005
    Date of Patent: January 13, 2009
    Assignee: Synthesys Research, Inc
    Inventors: Andrei Poskatcheev, Senthil Thandapani, Clint Fincher
  • Publication number: 20090005536
    Abstract: A method for preparing a crosslinked polymer coated controlled porosity glass (CPG) particle is provided. The method involves mixing CPG particles in a solution comprising polyvinylbenzylchloride and a first solvent at a temperature below 10° C. A second solvent is added and a crosslinking agent is added to the mixture. The first solvent is removed rapidly within 1½ hours of addition of the crosslinking agent. The crosslinking reaction is permitted to proceed and the mixture is then cooled and treated to remove any remaining solvent. The resulting coated CPG particles are washed and dried. Also provided a polymer coated CPG particles using for loading ligand thereon.
    Type: Application
    Filed: June 24, 2008
    Publication date: January 1, 2009
    Applicant: Prime Synthesis, Inc.
    Inventors: MARC L. ROTHSTEIN, Dianne M. Rothstein, Dan P. Lee
  • Patent number: 7467336
    Abstract: A method and apparatus to draw eye diagrams of multi-valued signals that remove non-data dependent effects is disclosed. An exemplary method includes collecting event counts at variable bit offsets, desired time offsets within one or more bit periods and desired voltage offsets within a voltage region of interest; removing non-data dependent effects from the collected event counts; generating a composite diagram of the desired time offsets within the one or more bit periods of interest and desired voltage offsets within the voltage region of interest; and displaying the composite diagram.
    Type: Grant
    Filed: January 24, 2005
    Date of Patent: December 16, 2008
    Assignee: Synthesys Research, Inc
    Inventor: Thomas E. Waschura
  • Patent number: 7456331
    Abstract: A skin-contacting adhesive composition is described which has improved initial tack, long-term adhesion, water uptake and translucency characteristics and may be prepared by melt extrusion. Uses of these compositions are also described, for example, their use in wound dressings, adhesive cushions, and transdermal drug delivery devices.
    Type: Grant
    Filed: November 7, 2006
    Date of Patent: November 25, 2008
    Assignees: Corium International, Inc., A.V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences
    Inventors: Valery G. Kulichikhin, Shoreh Parandoosh, Mikhail M. Feldstein, Sergey Antonov, Gary W. Cleary
  • Publication number: 20080182591
    Abstract: Described are methods and apparatuses, including computer program products, for mobile proximity-based notifications. The method includes receiving, by a mobile first device in proximity with a second device, an identifier wirelessly transmitted by the second device. The identifier is associated with a user of the second device. The method also includes determining, using an application running on the mobile first device, whether the identifier is included on a preexisting list stored on the mobile first device. The method also includes notifying a user of the mobile first device, if the identifier is included on the preexisting list, that the user associated with the identifier is in proximity to the mobile first device.
    Type: Application
    Filed: December 13, 2007
    Publication date: July 31, 2008
    Applicant: Synthesis Studios, Inc.
    Inventor: Raffi Krikorian
  • Patent number: 7386405
    Abstract: Apparatus and method for determining characteristics of a bit stream of binary pulses. The apparatus has control apparatus for defining a window comparator and logic apparatus for accumulating and mapping numbers derived from a count of the number of times the bit stream pulses fall at points inside the window comparator and drawing an eye diagram defining characteristics of the bit stream.
    Type: Grant
    Filed: March 14, 2006
    Date of Patent: June 10, 2008
    Assignee: Synthesys Research Inc
    Inventors: Thomas Eugene Waschura, Andrei Poskatcheev
  • Patent number: 7363562
    Abstract: A signal analysis circuit includes a sampling circuit operative to sample the characteristics of an input signal at various points within a bit window in response to a sample clock signal. A sampling control circuit is coupled to the sampling circuit and is operative to provide the sample clock signal in response to a sample control signal. The sample clock signal provides a variable time function such that the input signal characteristics may be sampled at several times during the input signal or bit window period. A control circuit is coupled to the sampling circuit and the sampling control circuit, and is operative to provide the sample control signal in response to the number of times the input signal is within a signal characteristic of interest. In an exemplary embodiment, the characteristic of interest is a reference pattern that may be synchronized with the input data signal.
    Type: Grant
    Filed: September 14, 2005
    Date of Patent: April 22, 2008
    Assignee: Synthesys Research Inc
    Inventors: Thomas E. Waschura, Andrei Willis, Clint Fincher
  • Publication number: 20080066634
    Abstract: A microcontact printing device including a tube member for storing or transferring a printing fluid or liquid and a printing element attached to an end of the fluid dispensing member. Further, a microcontact printhead device including a holder and at least one microcontact printing device disposed within the holder, the microcontact printing device including a tube member for storing or transferring a printing fluid or liquid and a printing element attached to an end of the fluid dispensing member. In addition, a method of fabricating a microcontact printing device including providing a wafer or substrate, micromachining a printing element from the wafer or substrate, providing a tube member for storing or transferring a printing fluid or liquid, and attaching the printing element to an end of the tube member.
    Type: Application
    Filed: September 24, 2007
    Publication date: March 20, 2008
    Applicant: Parallel Synthesis Technologies
    Inventors: Robert Haushalter, Srinivas Vetcha
  • Patent number: 7301325
    Abstract: A measurement device includes a measurement circuit that generates a parametric measurement data signal including parametric characteristics of an input signal. In an exemplary embodiment, the parametric characteristics are measured at predetermined increments of time. A population limit analyzer is coupled to the measurement circuit and generates limit data in response to the parametric measurement data signal. A measurement limit checker is coupled to the population limit analyzer and generates a signal indicating that the characteristics of the parametric measurement data signal is within acceptable limits. With this information, the user is able to quickly grade a selected device under test (DUT). A device performance measurement method includes receiving an input signal. Next, statistical characteristics are determined from the parametric measurements of the input signal. Performance limits are extrapolated from the statistical characteristics of the parametric measurements.
    Type: Grant
    Filed: January 21, 2005
    Date of Patent: November 27, 2007
    Assignee: Synthesys Research, Inc.
    Inventors: Thomas E. Waschura, James R. Waschura
  • Patent number: 7298220
    Abstract: Disclosed herein is a method and apparatus used to create an idealized voltage controlled oscillator (VCO) which allows very high modulation rates without the expected phase noise (jitter) which nominally comes from wide bandwidth VCOs. In this fashion, high quality VCOs that typically offer pure signals at the cost of small tuning bandwidths can be enhanced to create idealized VCOs that offer both high quality (low jitter) and high tuning bandwidths. A high-frequency phase modulator and control voltage processing is used in conjunction with a natural VCO to create a method and apparatus in accordance with the invention. The control voltage processing includes separation of frequency components of the controlling voltage and electrical integration of high-frequency control voltage components directed to the phase modulator to create the overall voltage-to-frequency transfer function for the ideal VCO.
    Type: Grant
    Filed: March 7, 2006
    Date of Patent: November 20, 2007
    Assignee: SyntheSys Research, Inc
    Inventor: Andre Willis
  • Publication number: 20070212267
    Abstract: A reactor apparatus includes at least one reaction capillary having a lumen for receiving a reactant to undergo a reaction, and a magnetron for irradiating reactant contained in at least a portion of the capillary with microwaves. A method of micro-reacting a reactant includes providing a capillary, and irradiating the reactant in the capillary with microwaves to facilitate a chemical reaction in the capillary by which the reactant is converted into a desired product.
    Type: Application
    Filed: February 28, 2007
    Publication date: September 13, 2007
    Applicant: Total Synthesis Ltd.
    Inventors: Michael Organ, Eamon Comer
  • Patent number: 7250510
    Abstract: The present invention relates to catalysts of transition metal complexes of N-heterocyclic carbenes, their methods of preparation and their use in chemical synthesis. The synthesis, ease-of-use, and activity of the compounds of the present invention are substantial improvements over in situ catalyst generation. Further, the transition metal complexes of N-heterocyclic carbenes of the present invention may be used as precatalysts in metal-catalyzed cross-coupling reactions.
    Type: Grant
    Filed: August 23, 2006
    Date of Patent: July 31, 2007
    Assignee: Total Synthesis, Ltd.
    Inventors: Michael G. Organ, Christopher J. O'Brien, Assam (Eric) B. Kantchev
  • Patent number: 7229500
    Abstract: Crystallization Photoresist (PR) apparatus and methods which allow for fast screening and determination of protein crystallization conditions with small protein quantities and rapid crystallization. The apparatus comprise a first region comprising a first nucleation catalyst material and a second region comprising a second nucleation catalyst material, with the first and second regions positioned adjacent to each other and configured to support at least one crystal, and with the first region having a variation in a nucleation property of the first nucleation catalyst material in the first region. The crystal may be supported at an interface of the adjacent regions.
    Type: Grant
    Filed: November 20, 2001
    Date of Patent: June 12, 2007
    Assignee: Parallel Synthesis Technologies, Inc.
    Inventors: Robert C. Haushalter, Xiao-Dong Sun
  • Publication number: 20070073055
    Abstract: The present invention relates to catalysts of transition metal complexes of N-heterocyclic carbenes, their methods of preparation and their use in chemical synthesis. The synthesis, ease-of-use, and activity of the compounds of the present invention are substantial improvements over in situ catalyst generation. Further, the transition metal complexes of N-heterocyclic carbenes of the present invention may be used as precatalysts in metal-catalyzed cross-coupling reactions.
    Type: Application
    Filed: August 23, 2006
    Publication date: March 29, 2007
    Applicant: Total Synthesis, Ltd.
    Inventors: Michael Organ, Christopher O'Brien, Assam (Eric) Kantchev
  • Publication number: 20070051376
    Abstract: A skin-contacting adhesive composition is described which has improved initial tack, long-term adhesion, water uptake and translucency characteristics and may be prepared by melt extrusion. Uses of these compositions are also described, for example, their use in wound dressings, adhesive cushions, and transdermal drug delivery devices.
    Type: Application
    Filed: November 7, 2006
    Publication date: March 8, 2007
    Applicants: Corium International, Inc., A.V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences
    Inventors: Valery Kulichikhin, Shoreh Parandoosh, Mikhail Feldstein, Sergey Antonov, Gary Cleary
  • Patent number: 7138458
    Abstract: A method is provided for preparing an adhesive composition that contains both a hydrophobic phase and a hydrophilic phase, wherein the hydrophobic phase is composed of a crosslinked hydrophobic polymer composition and the hydrophilic phase is a water-absorbent blend of a hydrophilic polymer and a complementary oligomer capable of crosslinking the hydrophilic polymer through hydrogen bonding, ionic bonding, and/or covalent bonding. The composition is useful as a bioadhesive, for affixing drug delivery systems, wound dressings, bandages, cushions, or the like to a body surface such as skin or mucosal tissue.
    Type: Grant
    Filed: October 12, 2004
    Date of Patent: November 21, 2006
    Assignees: Corium International, Inc., A.V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences
    Inventors: Gary W. Cleary, Mikhail M. Feldstein, Valery G. Kulichikhin, Danir F. Bairamov
  • Publication number: 20060171906
    Abstract: A new tooth whitening composition provides sustained release of high levels of whitening agent and is moisture-activated without significant swelling. A preferred system for applying the composition to the teeth is flexible, self-adhesive, and well-tolerated by users. In certain embodiments the tooth whitening composition comprises a mixture of tooth whitening agents, with a first whitening agent selected so as to release peroxide gradually upon contact with moisture and produce an alkaline pH, and a second whitening agent selected so as to release peroxide rapidly upon contact with moisture.
    Type: Application
    Filed: December 21, 2005
    Publication date: August 3, 2006
    Applicants: Corium International, Inc., A.V. Topchiev Institute of Petrochemical Synthesis Russian Academy of Sciences
    Inventors: Parminder Singh, Eun Lee, Appala Sagi, Mikhail Feldstein, Danir Bairamov
  • Patent number: 7062733
    Abstract: Sub-sampled signals are compared to determine time delay, calibration of delay elements, and other precise time domain measurements, based on properties of aliased signals produced by the sub-sampling. In one embodiment, flip-flops sub-sample an input signal and a delayed signal. A counter measures time delay between edges in the sub-sampled input and sub-sampled delayed signal. The time delay is determined and averaged over a measurement window, and then scaled to determine an amount of delay of the delayed signal. Means to calibrate a delay element inside a measurement device (e.g., Bit Error Ratio Tester), utilizing sub-sampling techniques to achieve precise measurements very quickly and without the need for factory calibration.
    Type: Grant
    Filed: March 15, 2002
    Date of Patent: June 13, 2006
    Assignee: SyntheSys Research, Inc.
    Inventors: Andrei Poskatcheev, Tom Helmer, Rob Verity