Abstract: The disclosure relates to a cleaning device for cleaning an application device which, in operation, applies at least one coating agent jet of a coating agent (e.g. paint) to a component (e.g. motor vehicle body component). The disclosure provides that a jet checking device is integrated into the cleaning device for checking the coating agent jet emitted by the application device, so that the cleaning device forms a structural unit with the jet checking device.

Abstract: The present invention relates to a transdermal therapeutic system for the transdermal administration of guanfacine comprising a guanfacine-containing layer structure, said guanfacine-containing layer structure comprising: A) a backing layer; and B) a guanfacine-containing layer; wherein the transdermal therapeutic system comprises at least one silicone polymer.

Abstract: A computer-implemented transaction method for a ZK-rollup network for a blockchain, with transaction rules governed by a ZK-rollup smart contract deployed on the blockchain, and with the ZK-rollup network comprising several user ZK-rollup nodes of which at least one is an aggregator ZK-rollup node. The method includes using the ZK-rollup smart contract to process a valid user transfer by computing a history root hash from content of the aggregator transfer transaction and from an immediately preceding history root hash, and storing the computed history root hash in a ZK-rollup contract state; and processing a withdrawal of funds to one or more blockchain addresses by receiving an aggregator withdrawal transaction from an aggregator ZK-rollup node, verifying the aggregator withdrawal transaction, and transferring funds according to the purported total amounts received and according to total amounts already withdrawn.

Abstract: The disclosure relates to a rotary atomizer for applying a spray jet of a coating agent (e.g. paint) to a component (e.g. motor vehicle body component). The disclosure provides that the construction dimensions of the rotary atomizer are coordinated in such a way that the air pressure at the outlet opening of the paint nozzle during operation is lower than the air pressure in the nozzle chamber of the bell cup and in the external rinsing channels in order to prevent a backflow of the coating agent from the outlet opening of the paint nozzle backwards in the direction of the nozzle chamber due to the pressure difference.

Abstract: The present invention relates to transdermal therapeutic systems (TTS) for the transdermal administration of asenapine comprising a self-adhesive layer structure containing a therapeutically effective amount of asenapine, such asenapine TTS for use in a method of treatment, processes of manufacture of such TTS as well as asenapine and transdermal therapeutic systems containing asenapine for use in a method of treatment and to a method of treating a human patient by transdermal administration of asenapine.

Abstract: The disclosure relates to a collecting device for collecting fluid media (e.g. rinsing agent, paint residues), which are produced when rinsing an atomizer (e.g. rotary atomizer) in a painting plant. The collecting device according to the disclosure comprises a collecting container with an insertion opening at the top of the collecting container for inserting the atomizer into the collecting container. Furthermore, the collecting device according to the disclosure comprises a lateral container wall which externally delimits the collecting container and is substantially impermeable to paint in order to prevent paint from escaping from the collecting container. The disclosure provides that the lateral container wall of the collecting container is at least partially air-permeable so that moist air can escape from the interior of the collecting container to the outside.

Abstract: A horizontal forming device, in particular for horizontal flow pack machines, comprises at least one, in particular roller-free, forming unit, in particular a forming shoulder, and comprises at least one support unit, which are configured for forming a packaging material web into a packaging material tube, wherein the forming unit and the support unit together delimit a guiding gap which the packaging material web can be guided through, the horizontal forming device further comprising at least one compensation unit, which is configured to movably support the forming unit and/or the support unit in such a way that, at least during a forming of the packaging material tube, the forming unit and the support unit are movable relative to each other, in particular in order to enable a compensation movement of the forming unit and/or the support unit relative to each other during a forming of the packaging material tube.

Abstract: The disclosure relates to a program-controlled coating robot for coating components. A robot path is preset and application parameters observed by the applicator are also preset based on real coating operation during movement along the robot path. There is a virtual determination of a coating result for the predetermined robot path and the predetermined application parameters. The disclosure provides steps for virtual determination of the coating result including generating real spray pattern data and/or reading out real spray pattern data from a database as a function of the predetermined robot path and/or the predetermined application parameters, the read-out real spray pattern data reproducing a spray pattern which the applicator generates during a real coating operation with the predetermined application parameters and/or on the predetermined robot path, and determining the coating result taking into account the real spray pattern data read out from the database or the generated spray pattern data.

Abstract: The invention relates to an emergency stop switch, having: a switch mechanism with a manually operable switch and with a first contact element which is operatively connected to the switch, wherein the switch is configured to bring the first contact element into contact with a second contact element to trigger an emergency stop function. A cable pull mechanism with a switch tongue guided in a switch tongue guide is connected to a first end of a cable, wherein a switch tongue spring preloads the switch tongue during operation in a direction away from the cable. The cable is connected on its second end with preload to an equalizing spring during operation, wherein the first contact element is operatively connected to the switch tongue.

Abstract: In order to provide a filter system for separating off contaminants from a stream of untreated gas that contains contaminants that is of simple construction and is operable efficiently, it is proposed that the filter system should include the following: a base construction through which the stream of untreated gas is guidable and which includes at least one filter module receptacle for receiving at least one filter module, and at least one filter module which is selectively arrangeable on and/or in the at least one filter module receptacle and/or removable therefrom, wherein the at least one filter module includes a plurality of filter element receptacles for receiving a plurality of mutually independent filter elements.

Abstract: The invention relates to a water treatment unit including a filter disposed downstream of a water inlet, wherein the water inlet is intended to supply the filter with water to be treated, a conduit system disposed downstream of the filter in order to remove treated water that has flowed through the filter in the direction of a water outlet for release of water to a user, and an ozone generator set up to introduce ozone into an ozone supply conduit, wherein the ozone supply conduit opens into the conduit system between the filter and the water outlet.

Abstract: Use of an additive in a transdermal therapeutic system with an active agent-containing layer in the form of a biphasic layer having a hydrophilic inner phase and a hydrophobic outer phase, in which the inner phase comprises the additive and an active agent dissolved therein, the additive has a higher affinity to water than to the active agent, for the control of the permeation rate of the active agent in a manner which is independent from its concentration in the biphasic layer, with the maintenance of the permeation rate proportional to the amount of active agent in the biphasic layer.

Abstract: Birdcage or birdcage-derived resonator for NMR experiments irradiation and detection having two electrically conducting, circular rings at opposing axial ends, joined and fastened with a number of mutually isolated parallel electrically conducting rods distributed over the circumference. The axially outer surfaces are spaced axially by a birdcage height, and either between each of the rods and the respective ring at least one capacitor is provided or in each of the rings at least one capacitor is provided in each of the ring segments between adjacent conducting rods. The capacitors are axial capacitor bars extending between the rings and beyond their outer surfaces forming at both axial sides salient portions, and the length of the salient portions at each side is at least 25% of the birdcage height.

Abstract: The disclosure relates to a coating method including the specification of at least one coating path for moving a paint impact point along at least one coating path over the surface, the at least one coating path running through a surface region of the component to be coated which is bounded by edges. The disclosure also includes, presetting reference values of the spatial edge point positions and/or of the edge point orientations of the surface region, spatial measurement of position, orientation and/or shape of the component to be coated or of a part of the component to be coated with a measuring system, where, in the course of the spatial measurement, measured values of the edge point positions and/or of the edge point orientations of the edge points on the edges of the surface region are measured.

Abstract: The present invention relates to an acceptor chamber for a Franz diffusion cell, comprising an upper opening closable by a membrane and, on the side wall of the acceptor chamber, an upper and a lower outlet opening designed to remove or add liquid medium from the acceptor chamber, the upper outlet opening being located within the upper two thirds of the side wall and the lower outlet opening is located in the lower quarter of the side wall, the upper and lower outlet openings being substantially opposite each other, to a Franz diffusion cell comprising a donor compartment and such an acceptor chamber, the donor compartment and the acceptor chamber being separated from each other by a membrane, and to a method for determining the diffusion of a substance through a membrane with such a Franz diffusion cell.

Abstract: For the purposes of working on eye tissue, an ophthalmological apparatus comprises a laser source that is configured to produce a pulsed laser beam, a focusing optical unit that is configured to focus the pulsed laser beam into the eye tissue, and a scanner system for deflecting the pulsed laser beam onto work target points in the eye tissue. The scanner system is configured to guide the pulsed laser beam onto work target points along a scan line that extends across a work line at an alignment angle and to tilt the scan line depending on the work target point on the work line in such a way that the scan line extends substantially along an outer face of a lenticule to be cut in the eye tissue.

Abstract: A device for producing microstructures, particularly microneedles and more particularly microneedle arrays, including a female mold that has, on a top side, at least one in particular conical depressed portion for producing a microstructure. The female mold is, for example, in the form of a silicone cap and is connected to a hollow cylinder, in particular via a holding element. A plunger is disposed movably inside the hollow cylinder.

Abstract: Described is an oral thin film comprising at least one matrix layer, wherein the at least one matrix layer comprises at least one pharmaceutically active agent, at least one polyvinyl alcohol and at least one polyvinyl alcohol-polyethylene glycol graft copolymer, a method for producing same, and use thereof as a medicament.

Abstract: The invention relates to a method for weighing pharmaceutical containers (10) nested in a carrier (11), in which at least one of the nested containers (10) is weighed by means of a weighing device (1), wherein a relative movement between the at least one pharmaceutical container (10) and the carrier (11) is brought about in order to release the pharmaceutical containers (10) from the carrier (11) in order to increase the weighing accuracy.

Abstract: The disclosure relates to a painting installation for painting components with a paint, in particular for painting motor vehicle body components, with a paint booth and an application device, in particular a print head, arranged in the paint booth, for applying the paint to the component located inside the paint booth, the application device operating essentially without overspray, so that the paint applied by the application device essentially completely on the component to be coated without overspray deposits. The disclosure provides that no paint separation is arranged below the first paint booth.