Abstract: The present invention relates to microarrays, sets of primers and methods for determining the co-receptor usage of a virus, in particular whether HIV uses CXCR4 or CCR5 as co-receptor. The methods and compositions of the invention are based on microRNA analysis. The invention can be used to determine virus tropism in any species or organism that expresses microRNAs, particularly in human beings.

Abstract: A method is provided for reinforcement of a multiple layer shear band as may be used in a non-pneumatic tire More particularly, an iterative method of improving the performance characteristics (such as e g, increasing the bending stiffness) of a shear band without increasing its thickness or of reducing the thickness of a shear band while maintaining its performance characteristics is presented Shear bands constructed according to this method are also provided.

Abstract: The invention relates to conjugates of products of interest including glycoproteins, nanoparticles, and imaging agents and of compounds of the general formula (1): that target the cation-independent mannose 6-phosphate receptor with a high affinity. The invention also relates to their applications, for instance in enzyme replacement therapies.

Abstract: A passenger vehicle tire, the crown reinforcement of which has three distinct elements, the three distinct elements comprising: a radial carcass reinforcement formed of reinforcing elements connecting the two beads of the tire, a crown belt comprising reinforcing elements parallel to the circumferential direction of the tire, and a crown triangulation layer comprising reinforcing elements making an angle of between 10 degrees and 80 degrees with the circumferential direction of the tire, the reinforcing elements of the triangulation layer having a flattened cross section.

Abstract: Non-pneumatic resilient wheel (10), that is supported structurally and defines three perpendicular directions, circumferential (X), axial (Y) and radial (Z). The wheel comprises a hub (11); an annular band referred to a shear band (13) comprising at least one inner circumferential membrane (14) and one outer circumferential membrane (16) that are oriented in the circumferential direction X; and a plurality of support elements (12) that connect the hub (11) to the inner circumferential membrane (14). The two membranes (14, 16) are connected to one another, in zones (17) referred to as anchoring zones, by means of a series (15A, 15B, 15C), that extends in the circumferential direction (X), of cylinder structures (15) referred to as connecting cylindrical structures that are non-touching in the circumferential direction X.

Abstract: A technique for improving the durability of the beads of a radial tire for a heavy vehicle of the civil engineering type, by reducing the rate of spread of cracks initiated at the turned-back end of carcass reinforcement and the spread through the coating, edge-binding and filler polymer materials.

Abstract: The invention relates to a rail clamp for fastening rail equipment, said rail clamp being integrally composed of a polymeric composition produced by pultrusion or molding, vacuum molding or compression molding. It has high mechanical strength. It is anticorrosive and insulating and is preferably composed of a resin and reinforcing fibers and/or a thermoplastic. It is advantageously formed as a one piece structure. The rail clamp is especially used to fasten rails to base slabs and has economic advantages compared to the rail clamps known in the art, which are made of steel coated with rubber.

Abstract: The invention relates to a method for optimizing the conductivity provided by the displacement of H+ protons and/or OH? ions in a conductive membrane made of a material permitting the insertion of steam into said membrane, wherein said method comprises the step of inserting under pressure gaseous flow containing the steam into said membrane in order to force said steam into said membrane under a certain partial pressure so as to obtained the desired conductivity at a given temperature, said partial pressure being higher than or equal to 1 bar, a drop in the operational temperature being compensated by an increase in said partial pressure in order to obtain the same desired conductivity. The invention can be used in particularly interesting applications in the fields of high-temperature water electrolysis for producing hydrogen, of the manufacture of fuel cells using hydrogen fuel, and of hydrogen separation and purification.

Abstract: Road-going assembly consisting of a vehicle comprising a front axle and a rear axle, and of a set of tires which are mounted on their mounting rim in order to be fitted to the front axle and the rear axle of this vehicle, the tires of the rear axle having grooves the mean depths of which are at least equal to 3 mm and at most equal to 5 mm, the tires of the front axle having grooves the mean depths of which are greater than 5 mm, this road-going assembly having, at least in the case of the rear axle, static setups (camber, toe-in) of close to zero, that is to say a camber of each wheel-tire assembly on the said axle of between ?0.8 degrees and +0.8 degrees and a toe-in at each wheel of between ?0.15 degrees and +0.15 degrees, the static setups of the tires of one and the same axle being equal in terms of absolute value and symmetric with respect to a plane perpendicular to the road surface.

Abstract: The invention relates to a blocked mercaptosilane of general formula I below: (HO)2R1—Si—Z—S—C(?O)-A in which: R1 represents a monovalent hydrocarbon-based group chosen from alkyls, which are linear or branched, cycloalkyls or aryls, having from 1 to 18 carbon atoms; A represents hydrogen or a monovalent hydrocarbon-based group chosen from alkyls, which are linear or branched, cycloalkyls or aryls, having from 1 to 18 carbon atoms; Z represents a divalent bonding group comprising from 1 to 18 carbon atoms.

Abstract: Process for the manufacture of an elastomer composition having a self-sealing property which is based on at least (phr meaning parts by weight per 100 parts of solid elastomer): a blend of at least two solid elastomers, a polybutadiene or butadiene copolymer elastomer, referred to as “elastomer A”, and a natural rubber or synthetic polyisoprene elastomer, referred to as “elastomer B”, the elastomer A:elastomer B ratio by weight being within a range from 10:90 to 90:10; between 30 and 90 phr of a hydrocarbon resin; from 0 to less than 30 phr of filler, in which, during a first stage or stage (a), a masterbatch comprising at least the elastomers A and B and between 30 and 90 phr of a hydrocarbon resin is prepared by mixing these various components in a mixer at a “hot compounding” temperature or up to a “hot compounding” temperature which is greater than the softening temperature of the hydrocarbon resin.

Abstract: An airplane tire has a carcass reinforcement that comprises at least two inner layers wrapped around the bead core from the inside to the outside of the tire to form respectively a turn-up, and at least one outer layer wrapped around the bead core from the outside to the inside of the tire, and axially outward, within the sidewall, of any inner layer. One of the at least two inner layers that is axially nearest the bead core is decoupled for at least a part of its length, in an area adjacent to and radially outward of the bead core, from the turn-ups and carcass reinforcement layers which are axially outward of it, by at least one polymeric bead filler compound.

Abstract: A portable pneumatic power wrench has a housing with a handle, a motor, a pressure air inlet passage, and an outlet passage for ducting exhaust air from the motor out of the housing. An outlet unit is connected to the outlet passage and has a first outlet opening section forming a main exhaust air flow path, a second outlet opening section forming an additional exhaust air flow path, and a manually operable valve arranged to control the additional exhaust air flow path by opening or closing the second outlet opening section. The total outlet flow area of the main exhaust air flow path and the additional exhaust air flow path gives an augmented torque output of the power wrench.

Abstract: There is provided a method and control system for reducing noise in a power converter by controlling a switching device in the power converter according to a modulation scheme. The switching device couples a direct current (DC) source to provide an alternating current (AC) output at a particular switching frequency. The method includes the step of, in each switching period, switching the switching device between active configurations providing a finite voltage at the output and inactive configurations providing a zero voltage at the output. The ratio between the total period of time in which the switching device is in an active configuration and the total period of time in which the switching device is in an inactive configuration is the same for each switching period and is determined according to the desired voltage at the AC output.

Abstract: A method of determining relief elements on a tyre surface includes capturing a three-dimensional image of the surface and assigning to each pixel (i, j) of the image a grey-level value proportional to a topographic elevation of a point corresponding to the pixel, so as to obtain a starting image (f). The method also includes transforming the starting image (f) by a first top-hat operation, with aid of a first structuring element, so as to obtain an image (f1) flattened by differencing, (f1=f??31,150(f)). The method further includes performing a thresholding operation on the image flattened by differencing, so as to obtain a segmented image, (T<1,30>(f1)=seg1) in which relief elements appear white on a black background.

Abstract: Tire tread for civil engineering works vehicle, this tread having a tread surface (10) intended to come into contact with the ground, this tread comprising a central part (21) delimited by grooves (3) of circumferential overall orientation, these grooves delimiting lateral parts (22) axially towards the outside of the central part (21), each lateral part (22) being provided with a plurality of transverse grooves (6) delimiting a plurality of blocks (7), the transverse grooves (6) having a cross section of minimum area (ST) and being distributed substantially uniformly in the circumferential direction, this tread being characterized in that the central part (21) is provided with a plurality of channels (51) extending transversely under the tread surface (10) and passing right through the said central part (21), each channel (51) comprising a first and a second end (52, 51), these first and second ends opening into the grooves (3) of circumferential overall orientation, at least one end of each channel opening