Abstract: A method which is implemented by an access point, and in which requests are received from a number of user devices, in which each of the requests specifies one or multiple requested file blocks of at least one file. A set of multicast groups is determined based on the received requests, and each multicast group contains a set of indices of one or multiple of the user devices and a set of indices of the file blocks which are to be transmitted to the user devices indicated in the multicast group. For each multicast group of the set the file blocks indicated in the multicast group are retrieved and encoded, and a forward error correction process is used. For each of the multicast groups of the set the encoded file blocks indicated in the multicast group are transmitted to the user devices indicated in the multicast group.

Abstract: The present invention relates to polypeptides for use in treating diseases or disorders of energy homeostasis such as obesity, dyslipidemia, diabetes, insulin resistance, hyperglycemia or the metabolic syndrome. The invention also relates to polynucleotides encoding said polypeptides for use in treating diseases or disorders of energy homeostasis. Also provided by the present invention are pharmaceutical compositions comprising said polypeptides and polynucleotides for use in treating diseases or disorders of energy homeostasis. Said polypeptides, polynucleotides and pharmaceutical compositions may be administered locally, in particular locally into the visceral adipose tissue. Another aspect of the invention relates to a cosmetic product and the use of said cosmetic product for reducing body weight, in particular for reducing abdominal adipose tissue.

Abstract: The present invention relates to a method of determining a distance or location of a remote device or reflector, the method comprising: receiving a signal from a remote signal transmitter associated with or contained in or attached to the remote device; estimating a first propagation delay associated with the received signal, wherein the first propagation delay represents a first candidate for a correct propagation delay; deriving a relationship between the first candidate and one or more other candidates for a correct propagation delay from the received signal; determining a plurality of other candidates for a correct propagation delay based on said relationship; generating a likelihood histogram based on said candidates for a correct propagation delay; selecting a propagation delay from said candidates based on the likelihood histogram; and determining a distance or location of the remote device or reflector using the selected propagation delay.

Abstract: The present invention provides means and methods for selectively detecting activated MALT1 in a sample. Moreover, the present invention provides a method for diagnosing diseases, which are characterized by an increased MALT1 activity. Finally, the present invention provides methods for identifying patients which are amenable to treatment with a therapeutic agent capable of inhibiting MALT1 activity.

Abstract: The disclosure relates to a manually operable tactile input/output device for a data processing system, in particular a tactile computer mouse, which is configured with a housing and a plurality of actuators in operative connection with the housing and in which the actuators are arranged and jointly controlled in the housing to cause at least temporarily a tactile perception by a user in manual contact with the housing, by which simultaneously at least two and in particular all five tactile perception dimensions of microscopic roughness, macroscopic roughness, friction, hardness and heat are simulated. Furthermore, the disclosure relates to an operating method for a manually operable tactile input/output device and a data processing system.

Abstract: The disclosure relates to a method for generating a mesh, wherein the method is performed by a processor of a computing device and comprises steps of: receiving a model, constructing a function representing geometric properties of the model, determining a total number of particles to be distributed on the model, distributing the particles on the model until the particles reach a final position, wherein constraints provided by the function are taken into account when distributing the particles, and triangulating the particles in the final position for generating an unstructured mesh. Further, a system for generating a mesh is disclosed.

Abstract: A device for coating cylinder walls of an internal combustion engine forming a plurality of cylinders. A coating device is provided for each cylinder, the coating devices are controlled in such a way that the cylinder walls of all the cylinders are coated simultaneously.

Abstract: The present invention relates to a prostate-specific membrane antigen (PSMA)-specific binding protein, wherein the PSMA-specific binding protein is a lipocalin 2 (Lcn2)-derived binding protein and binds to PSMA with a KD of 10 nM or lower. The present invention also relates to a nucleic acid molecule encoding the PSMA-specific binding protein of the invention, a vector comprising said nucleic acid molecule of the invention and a host cell transformed with the vector. Furthermore, the invention relates to a method of producing the PSMA-specific binding protein of the invention, the method comprising culturing the host cell of the invention under suitable conditions and isolating the PSMA-specific binding protein produced. The present invention further relates to a protein conjugate comprising the PSMA-specific binding protein of the invention, or the PSMA-specific binding protein produced by the method of the invention.

Abstract: The present disclosure presents a visuo-haptic sensor, which is based on a passive, deformable element whose deformation is observed by a camera. In particular, the improved simplified sensor may determine the force and/or torque applied to a point of the sensor in multiple spatial dimensions.

Abstract: The present invention relates to a novel method for the treatment and/or prophylaxis of a tau-mediated neurodegenerative disease and/or of a tau-mediated neurodegenerative pathological condition, especially of a neurodegenerative disease and/or of a neurodegenerative pathological condition associated with and/or accompanied by tau aggregation, and in particular for the treatment and/or prophylaxis of a tauopathy; compounds and/or agents and compositions for such treatment and/or prophylaxis, and the manufacture of the compounds and/or agents and compositions suitable for the said treatment and/or prophylaxis. In this regard, the present invention relates especially to the use of compounds acting as PERK activator, a prodrug thereof, a derivative thereof and/or a pharmaceutically acceptable salt of any thereof, as a medicament.

Abstract: Contacting apparatus for contacting an energy storage cell (1) comprising at least one printed circuit board (5) which is provided for discharging the electrical energy stored in the energy storage cell (1), wherein at least one electric pole of the energy storage cell (1) is pressed by a releasable mechanical connection (7) with a specific contact pressing force against an electrically conductive layer (5c) of the at least one printed circuit board (5) which is located on a front side of the at least one printed circuit board (5) facing the energy storage cell (1).

Abstract: The present invention provides compounds binding to neuropathological aggregates of peptides or proteins, including aggregates such as neurofibrillary tangles (NFTs), osynuclein aggregates and other amyloid aggregates. The compounds of the present invention are useful for the detection and/or diagnosis of disorders associated with such neuropathological aggregates. In further aspects, the invention provides diagnostic compositions comprising these compounds, and methods for the preparation of radiolabeled compound from non-radiolabeled precursors.

Abstract: A production device for layer-by-layer manufacture of a three-dimensional object, comprising a feeding device for feeding in of a starting material, and an application device for melting the starting material and for layer-by-layer shaping of the melted starting material into the object, wherein the feeding device comprises a drying device for drying of the starting material, or a drying device is connected upstream of the feeding device.

Abstract: A method and apparatus for modeling smoke turbulence is disclosed. The method of modeling smoke turbulence includes detecting a turbulent area comprising smoke turbulence in a low-resolution image, and searching for a high-resolution patch matching the turbulent area in a memory that comprises high-resolution patches representing smoke turbulence extracted from high-resolution images. The method also models the smoke turbulence by synthesizing the retrieved patch to the low-resolution image.

Abstract: A method for coating a cylinder wall of an internal combustion engine, in which the cylinder wall is roughened prior to coating, such that the cylinder wall is compressed prior to roughening by plastic deformation.

Abstract: A method for machining a wall of a cylinder of an internal combustion engine, in which recesses in the wall are introduced by mechanical machining. The invention is characterized in that the wall is radiated with a medium under high pressure after the mechanical machining in order to introduce micro-recesses.

Abstract: The disclosure refers to a synthesis filter bank, comprising: a transform module which is configured to receive a plurality of input signals, transform the plurality of input signals, and output a plurality of transformed signals, a plurality of filter modules, which are coupled to the transform module, and wherein each filter module of the plurality of filter modules is configured to receive two transformed signals from the transform module, process the two received transformed signals and output two processed signals, and a parallel-to-serial module which is coupled to the plurality of filter modules and which is configured to receive the processed signals from the plurality of filter modules, combine the received processed signals and output a combined signal. Furthermore, an analysis filter bank, a filter bank and methods for operating a synthesis filter bank and for operating an analysis filter bank are disclosed.

Abstract: The present invention relates to a nucleic acid molecule comprising a low repetitive nucleotide sequence encoding a proline/alanine-rich amino acid repeat sequence. The encoded polypeptide comprises a repetitive amino acid sequence that forms a random coil. The nucleic acid molecule comprising said low repetitive nucleotide sequences can further comprise a nucleotide sequence encoding a biologically or pharmacologically active protein. Further, the present invention provides for selection means and methods to identify said nucleic acid molecule comprising said low repetitive nucleotide sequence. The present invention also relates to a method for preparing said nucleic acid molecules. Also provided herein are methods for preparing the encoded polypeptide or drug conjugates with the encoded polypeptide using the herein provided nucleic acid molecules. The drug conjugate may comprise a biologically or pharmacologically active protein or a small molecule drug.

Abstract: A system and method for the evaluation of hearing implant signal processing is described. A cochlear implant signal processor converts a speech signal input into multi-channel stimulation pulse sequences for a cochlear implant electrode array. A temporal feature processing module extracts temporal feature information from the stimulation pulse sequences. A speech recognition engine evaluates the temporal information using automatic speech recognition to produce speech recognition outputs corresponding to the speech signal input.

Abstract: The present invention relates to immunogenic compositions and their use in the prevention or treatment of diseases or disorders caused by or associated with Helicobacter pylori, in particular H. pylori infection and gastroduodenal disorders caused by H. pylori. The present invention further relates to methods of detecting H. pylori infection in a subject.