Abstract: A driver device (hexalobe or otherwise) that includes a handle portion, an elongate shaft portion, and an end portion that includes a screw engagement portion and a split manufactured offset from the central axis of the end portion and/or the screw engagement portion, forming two asymmetric halves of the end portion and/or screw engagement portion. This screw engagement portion is slightly oversized relative to the corresponding tool engagement recess of the locking cap, set screw, or bone screw. Thus, when the screw engagement portion is pressed into the corresponding tool engagement recess of the locking cap, set screw, or bone screw, the split manufactured offset from the central axis of the end portion and/or the screw engagement portion allows the screw engagement portion to compress slightly, creating a friction fit between the screw engagement portion and the corresponding tool engagement recess of the locking cap, set screw, or bone screw.

Abstract: The method including receiving, at a first node of a plurality of computing nodes, a message ownership migration request for a first message. The message ownership migration request can originate from a second node of the plurality of computing nodes. The first node can be an owner of the first message in a first instance of a message queue at the first node. The first message can be published from a first publisher to the message queue at one of the nodes of the plurality of computing nodes. The first message in the first instance of the message queue at the first node can be replicated at a second instance of the message queue at the second node. A first subscriber can be subscribed to the second instance of the message queue at the second node. The method also can include designating the second node as a new owner of the first message such that the first node is no longer the owner of the first message.

Abstract: Provide in the present invention is a method for preparing canagliflozin intermediate 2-(2-methyl-5-bromobenzyl)-5-(4-fluorobenzene)thiophene. The method comprises a compound, shown as formula (II), of (5-bromo-2-methylphenyl)[5-(p-fluorophenyl)thiophene-2-yl]ketone being reduced under the action of a directly used borane solution or borane locally produced by reacting alkali metal borohydride with a Lewis acid in a suitable solvent and at a suitable temperature, so as to obtain the compound of formula (I) of 2-(2-methyl-5-bromobenzyl)-5-(4-fluorobenzene)thiophene. The preparation method avoids the use of expensive reductive agents and guarantees the complete conversion of raw materials, wherein the post-treatment is simple, the purity of product obtained is high, the reaction yield is high, in the preparation method is simple and convenient, and can easily be used in industry.

Abstract: A main pole has a front end face including a first end face portion and a second end face portion. A plasmon generator has a near-field light generating surface. A surrounding layer has a first surrounding layer end face and a second surrounding layer end face located on opposite sides of the first end face portion in the track width direction. A gap film has a first gap film end face and a second gap film end face located on opposite sides of the near-field light generating surface in the track width direction. Each of the first and second gap film end faces includes a portion located between the first and second surrounding layer end faces, but does not include any portion interposed between the first surrounding layer end face and the first end face portion or between the second surrounding layer end face and the first end face portion.

Abstract: An array of solar collectors track the sun based on measured values of power output from the array and from a sun sensor on the array. The sun is tracked by periodically adjusting the altitude and azimuth of the array so the collectors remain pointed at the sun to maximize an amount of solar flux reflected from the collectors. The sun sensor, which detects alignment of the sun, recognizes when relative movement of the sun causes about a 10% reduction in power output of the array. The altitude and azimuth of the array are readjusted based on output from the sun sensor. While the array is being reoriented, power output from the array is monitored, and values for power output versus orientation of the array are recorded. Offset values between the power output, sun sensor output, and the ephemeral equations are calculated by comparing these values during operation.

Abstract: Compounds, pharmaceutical compositions and methods for treating viral and bacterial infections, by administering certain thiourea compounds, specifically acylthiourea, carboximidoylthiourea and S-alkyl isothiourea derivatives and analogs, in therapeutically effective amounts are disclosed.

Abstract: In a wireless content sharing system, audio may be captured at various levels of a source device, including at an application level. Audio may also be divided into components prior to packetization and transmission, allowing different channels of audio to be sent to different target devices. Audio may be sent with timing information to coordinate playback of content. Audio may be buffered to reduce user noticeable latency.

Abstract: The present disclosure provides oxidative coupling of methane (OCM) systems for small scale and world scale production of olefins. An OCM system may comprise an OCM subsystem that generates a product stream comprising C2+ compounds and non-C2+ impurities from methane and an oxidizing agent. At least one separations subsystem downstream of, and fluidically coupled to, the OCM subsystem can be used to separate the non-C2+ impurities from the C2+ compounds. A methanation subsystem downstream and fluidically coupled to the OCM subsystem can be used to react H2 with CO and/or CO2 in the non-C2+ impurities to generate methane, which can be recycled to the OCM subsystem. The OCM system can be integrated in a non-OCM system, such as a natural gas liquids system or an existing ethylene cracker.

Abstract: Provided herein are methods and compositions for treating a subject suffering from a deficiency in ?-L-Iduronidase in the CNS. The methods include systemic administration of a bifunctional fusion antibody comprising an antibody to a human insulin receptor and an ?-L-Iduronidase. A therapeutically effective systemic dose is based on the specific CNS uptake characteristics of human insulin receptor antibody-?-L-Iduronidase fusion antibodies as described herein.

Abstract: A mobile gaming device is configured for dynamic and location-specific noise suppression. The device samples ambient sounds via a sound receiver, and identifies a profile of ambient sounds and exception sound signatures for a current location. Resident sound emitters are directed to emit sound waves which locally suppress ambient sounds, but local suppression may be disabled for sounds associated with the exception sound signatures. The device may further locally amplify sounds associated the gaming application, and in some embodiments may locally amplify sounds associated with the exception sound signatures, such as for example location-specific alerts. In various embodiments, a plurality of mobile gaming devices in a common location may exchange ambient sound information. In various embodiments, the mobile gaming devices are coupled to a central server which generates a baseline profile for each gaming zone and directs local noise suppression.

Abstract: A telepresence device may relay video, audio, and/or measurement data to a user operating a control device. A user interface may permit the user to quickly view and/or understand temporally and/or spatially disparate information. The telepresence device may pre-gather looped video of spatially disparate areas in an environment. A temporal control mechanism may start video playback at a desired point in a current or historical video segment. Notations may be associated with time spans in a video and recalled by capturing an image similar to a frame in the time span of the video. An area of interest may be selected and video containing the area of interest may be automatically found. Situational data may be recorded and used to recall video segments of interest. The telepresence device may synchronize video playback and movement. A series of videos may be recorded at predetermined time intervals to capture visually trending information.

Abstract: A microprocessor includes a translation lookaside buffer and a first request to load into the microprocessor a page table entry in response to a miss of a virtual address in the translation lookaside buffer. The requested page table entry is included in a page table. The page table encompasses a plurality of cache lines including a first cache line that includes the requested page table entry. The microprocessor also includes hardware logic that makes a determination whether a second cache line physically sequential to the first cache line is outside the page table, and a second request to prefetch the second cache line into the microprocessor. The second request is selectively generated based at least on the determination made by the hardware logic.

Abstract: A reactor apparatus includes a first chamber coupled to a first source of vacuum, a monitor chamber isolated from the first chamber and coupled to a second source of vacuum, and at least one removable deposition monitor disposed in the monitor chamber.

Abstract: A high-speed transportation system, the system having at least one enclosed volume that is configured to be maintained as a low-pressure environment, at least one track along a transportation path within the at least enclosed volume; and a plurality of capsules configured for travel through the at least one enclosed volume between stations. The at least one enclosed volume is at least partially defined by at least one flexible material structured and arranged to withstand a tensile load.

Abstract: A method for producing sterile, decellurized bioprosthetic tissue comprising: (a) contacting a human tissue with a hypotonic solution to produce a lysed tissue, (b) contacting the lysed tissue with a first surfactant to produce a surfactant-treated tissue, (c) contacting the surfactant-treated tissue with a nuclease enzyme solution to produce an enzyme-treated tissue, (d) contacting the enzyme-treated tissue with a cleaning solution comprising a second surfactant, a chaotropic agent or a mixture thereof to produce a decellurized tissue and (e) contacting the decellurized tissue with a bioburden reducing agent to produce the final bioprosthetic tissue. Kits to be used in conjunction with said method, as well as, the bioprosthetic tissue produced via said method are also provided.

Abstract: There is disclosed a cleaning apparatus for a radiation source assembly in a fluid treatment system. The clean apparatus comprises a cleaning sleeve moveable to remove fouling materials from an exterior portion of the radiation source assembly, the cleaning sleeve comprising at least one chamber for receiving a cleaning fluid and a cleaning sleeve inlet in fluid communication with the at least one chamber and a first conduit element for conveying the cleaning fluid to the cleaning sleeve inlet, the first conduit element being configured such that a distal portion of the first conduit element is in fluid communication with the cleaning sleeve inlet and a proximal portion of the first conduit element is disposed outside of fluid being treated in the fluid treatment system.

Abstract: An apparatus includes an upstream/downstream probability module that determines, for each measurement point in an electrical power system, an upstream/downstream probability. The apparatus includes a zone module that identifies a plurality of zones within the power system and an upstream/downstream module that identifies, for each measurement point and for each zone, if a power quality event in a zone is upstream or downstream of a measurement point. The apparatus includes a zone probability module that determines a zone probability for each zone by multiplying the upstream probability or the downstream probability for each measurement point. The zone probability is a probability that the event happened in a zone. The zone probability module uses the upstream probability of a measurement point when the zone is upstream of the measurement point and uses the downstream probability when the zone is downstream of the measurement point.

Abstract: Methods for providing a metal surface structure and treatment process to prevent the corrosion (e.g., high electrochemical potential oxidization and hydrogen embrittlement) of a metallic component used in electrolyzer operational conditions. The oxide surface scale of a metal plate is used to prevent the corrosion, and electrical conductive materials such as e.g., precious metals or carbon are used to provide the surface electrical conductance of the metallic components. The methods advantageously produce, at a low cost, metal components for electrolyzers that need high electrical conductance and corrosion resistance for long term operation.

Abstract: A positioning frame structure for the centering and positioning of an IC is disclosed, in which the positioning frame structure comprises an IC carrier having a first chamber defined therein and an IC positioning magnet disposed in the first chamber of the IC carrier. The positioning frame structure further comprises an IC holder disposed over the IC positioning magnet, and the IC is held on the IC holder, so as to provide centering and positioning of the IC relative to the IC positioning magnet. The present invention can be used to control the centering and positioning of the IC and the positioning magnet on the carrier. The positioning magnet can be made to be larger than the IC. In addition, a large air gap can be obtained so as to facilitate the subsequent operation of the IC. Furthermore, without the operation using adhesive, the technical solution of the present invention saves the cost of operation.

Abstract: A data storage device is disclosed comprising a disk, a head, and a shock sensor comprising a first terminal and a second terminal. A first bias signal is applied signal to the first terminal of the shock sensor and a second bias signal is applied to the second terminal of the shock sensor. An oscillating signal is generated by increasing the first bias signal and decreasing the second bias signal, and a resonant frequency of the shock sensor is detected based on the oscillating signal. A physical shock affecting the head actuated over the disk is detected based on a response of the shock sensor to the physical shock and based on the detected resonant frequency of the shock sensor.