Abstract: Cyclosiloxanes are produced by the acid-catalyzed redistribution of siloxane bonds in polysiloxane fluids at a temperature of about 20-200.degree. C. Little catalyst and no water or solvent is required. Cyclosiloxane product mixtures contain .ltoreq.1 wt. % cyclosiloxane species having more than 18 silicon-oxygen bonds, and .ltoreq.0.5 wt. % cyclosiloxanes having 6 or fewer silicon-oxygen bonds, based upon the weight of the product mixture. The process may be carried out in continuous fashion where redistribution is carried out simultaneously with the stripping of cyclics from the equilibration mixture.

Abstract: A gene is described which is involved in the neoplastic process of a number of different cancers. The gene, termed TCL-5, is located at chromosome 1, band 32, adjacent to the chromosome junction formed during a t(1;14)(p32;q11) translocation. Probes and primers for detecting TCL-5 rearrangements are provided, as well as methods for detecting abnormalities in TCL-5 expression.

Abstract: An insect bait station comprising a first compartment with a hydrated macel containing at least one species of entomopathogen and a second compartment containing a hydrated water retentive compound layer which acts as a water-reservoir for the entomopathogen.

Abstract: The invention provides a process for producing high phase purity ceramic materials through the utilization of organic gelling agents. The process comprises the following steps: (a) dissolving stoichiometric amounts of metal salts in a solvent to form a solution; (b) heating the solution to a temperature sufficient to dissolve the gelling agent; (c) dissolving from about 0.1 to about 50 weight percent of an organic gelling agent into the heated solution; (d) cooling the solution to form a gel; (e) drying the gel to form a xerogel precursor; and (f) subjecting the xerogel precursor to a calcination process to produce a high phase purity ceramic material.

Abstract: A method and system for displaying a function in two dimensions where the function is made up of numerous independent variables and at least one dependent variable. A new independent variable value can be defined having values which correspond to the multiple dependent variables. The variable values are read into a computer and the independent variables are then ranked by the user from fastest- to slowest-running variable. Each dependent variable corresponding to the new independent variable is plotted along the Y-axis. The independent variable values are plotted along the X-axis in a hierarchical manner. The hierarchical manner involves a nesting of fastest-running variables within slower-running variables. Rectangles are then drawn to correspond to each variable value. Each rectangle horizontally encloses the faster-running variables associated with it.

Abstract: A very specific area of chromosome 10, band q11 is taught to be the site of chromosome breakpoints which occur in the course of translocations. The translocation brings sequences of the T-cell antigen receptor delta locus into adjacency with the specific area on chromosome 10. The area of chromosome 10 is presumed to carry an oncogene which is activated by the proximity to the delta locus. Methods and molecular probes and primers are taught for determining the presence of this particular translocation.

Abstract: Optically active compounds of the formula ##STR1## wherein n is 1 or 2 and m is 0, 1, 2 or 3 have antiviral activity. Compounds of the formula wherein at least one of the internucleotide phosphorothioate linkages isREFERENCE TO GOVERNMENT GRANTThe invention described herein was made, in part, in the course of work supported by National Institutes of Health grant PO1 CA-29545 and National Science Foundation grant DMB84-15002.

Abstract: Antimaturation factor (platelet factor 4 or active peptide segments thereof) is employed in the clinical treatment of coagulation disorders as an anticoagulant operating via an autoregulator mechanism for selectively suppressing megakaryocytopoiesis. Exposure of immature megakaryocytes to antimaturation factor reversibly inhibits cell maturation and, accordingly, functions characteristic of the mature cell, including platelet production and expression of genes coding for platelet coagulation factors, are reversibly suppressed.

Abstract: A hyperthermic treatment of lung cancer, by temporarily filling with a liquid medium preselected pulmonary air passages adjoining pulmonary tissues containing malignant cells, circulating exogenously heated liquid medium at from about 41.degree. to abThis invention was made with government support under Small Business Innovation Research Program Grant No. 1 R43 CA48611-01 awarded by the Public Health Service, Department of Health and Human Services. The government has certain rights in the invention.

Abstract: A method of making and using a liquid crystal cumulative dosimeter container including a resilient outer body sealed to confine a first liquid crystal composition constituent and a second liquid crystal composition constituent and having at least one transparent section to permit observation of the color of the confined composition, and a barrier contained completely within and physically unattached to the outer body for separating the first constituent from the second constituent, whereby disruption of the barrier allows the first constituent to mix with the seocnd constituent. The barrier is formed either by encapsulating one or both of the constituents or by using air bubbles.

Abstract: At least one radiopaque sphere of known dimensions with means for positioning same in a radiographic image field and a method for scaling radiographic images including straight AP and lateral views using such a radiopaque sphere.

Abstract: Bcl-3 gene sequences can be used to monitor the success of chemotherapy and to detect minimal residual disease in patients having hematopoietic malignancies. Bcl-3 sequences can also be used to identify new cellular oncogenes involved in hematopoietic cell malignancies by taking advantage of their adjacency to the bcl-3 promoter. Particular nucleic acid probes and primers are also provided by the disclosure.

Abstract: Electrically conductive carbon flakes and films are prepared in high yield by the pyrolysis of cyclic aromatic hydrocarbons, optionally halogenated, in the presence of a dehydrogenating agent at about at least 800.degree. C. Flakes of thicknesses up to 20 .mu.m and lengths up to 1 cm on a side are metal-like in appearance and have a conductivity of about 200-300 S/cm at room temperature. By heat treatment to 2600.degree. C., graphitic order is improved and the conductivity rises to .apprxeq.10000-15000 S/cm.

Abstract: An insecticidal composition in the form of a hydrated macrogel containing at least one species of entomopathogen and a hydrated water retentive compound which acts as a water-reservoir for the entomopathogen. Optionally, the macrogel contains attractants, in particular raffinose and gamma-irradiated, fungal-decayed wood.

Abstract: A microcapsule comprising an aqueous core, and capsular membrane formed from the interfacial reaction product of a hydrophilic polymeric Lewis acid or salt thereof with a lipophilic Lewis base or salt thereof.

Abstract: The present invention is directed to new artificial base pairs comprising complementary artificial purines and pyrimidines and methods of using artificial complementary base pairs.

Abstract: A multiple lumen catheter specifically adapted for selective visualization of one or the other of the coronary arteries. One lumen of the multiple lumen catheter is adapted to deliver contrast agent to the coronary artery to be visualized while a second, and optionally a third, lumen is adapted to limit flow of contrast agent to one or more other locations in the aortic root complex. The invention also includes a method of preparing for coronary angiography using such a catheter.

Abstract: A composition and method for nasal administration of pharmaceuticals utilizes glycyrrhetinic acid as an absorption enhancer. The composition comprises an effective amount of the pharmaceutically active substance, glycyrrhetinic acid, in an amount effective for enhancing permeation of the active substance across the nasal membrane, and a basic salt of an amino acid as an adjuvant. The composition may be administered to the nasal cavity in the form of a spray by using an atomizer, nebulizer, spayer, dropper or other device which ensures contact of the composition with the nasal mucus membrane.

Abstract: A container for a liquid crystal cumulative dosimeter including a resilient outer body sealed to confine a first liquid crystal composition constituent and a second liquid crystal composition constituent and having at least one transparent section to permit observation of the color of the confined composition, and a barrier contained completely within and physically unattached to the outer body for separating the first constituent from the second constituent, whereby disruption of the barrier allows the first constituent to mix with the second constituent. The barrier is formed either by encapsulating one or both of the constituents or by using air bubbles. Methods of manufacturing the various containers shown and processes of using those containers are also disclosed.

Abstract: A device consisting of a wire for occluding an aperture within a body surface, such as atrial and ventricular septal defects (and the method of using such a device). The wire comprises two configurations, an elongated configuration for passage into said body through a catheter and through the aperture, and a preprogrammed configuration including occlusion-forming wire segments, one on each side of said aperture. The wire also includes means (preferably a temperature-induced shape change) for changing the wire from the elongated configuration to the preprogrammed configuration in the body.