Patents Assigned to Texas A & M University System
  • Publication number: 20200110050
    Abstract: Systems and methods for detecting defects in pipelines are disclosed. In one embodiment, a method for detecting defects in pipelines includes: generating an electrical signal in a first pipeline by a signal generator electrically connected with the first pipeline and a second pipeline. A reflected signal is acquired by data acquisition equipment electrically connected with the first pipeline and the second pipeline. The reflected signal at least partially reflects from a defect in the first pipeline or the second pipeline. The method also includes analyzing the reflected signal to determine at least one of a location of the defect and a severity of the defect. In some embodiments, the first pipeline and a second pipeline are connected with a shunt cable.
    Type: Application
    Filed: April 6, 2018
    Publication date: April 9, 2020
    Applicant: THE TEXAS A&M UNIVERSITY SYSTEM
    Inventors: Homero Castaneda-Lopez, Tristan Petit de Servins d'Hericourt
  • Patent number: 10615823
    Abstract: A method and system for decoding low density parity check (“LDPC”) codes. A method and system for decoding low density parity check (“LDPC”) codes. An LDPC code decoder includes decoding circuitry configured to process blocks of an LDPC matrix. The decoding circuitry includes a control unit that controls processing by the decoding circuitry. The control unit is configured to cause the decoding circuitry to process blocks of a layer of the LDPC matrix out of order.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: April 7, 2020
    Assignee: The Texas A&M University System
    Inventors: Kiran Kumar Gunnam, Gwan S. Choi
  • Patent number: 10604764
    Abstract: The invention provides cotton event TAM66274, and plants, plant cells, seeds, plant parts, and commodity products comprising event TAM66274. The invention also provides polynucleotides specific for event TAM66274 and plants, plant cells, seeds, plant parts, and commodity products comprising polynucleotides specific for event TAM66274. The invention also provides methods related to event TAM66274.
    Type: Grant
    Filed: July 9, 2018
    Date of Patent: March 31, 2020
    Assignee: The Texas A&M University System
    Inventors: Keerti S. Rathore, Devendra Pandeya, LeAnne M. Campbell, Sreenath R. Palle
  • Patent number: 10604763
    Abstract: The invention relates to genetic constructs encoding a compartmenting peptide, wherein expression of the compartmenting peptide leads to formation of a droplet body comprising a targeted biological product, and to vectors including such constructs. The invention also relates to methods of increasing the yield of a biological product in a plant, and to methods for producing a transgenic plant which produces an increased yield of a biological product. The invention also relates to transgenic plants, host cells, plant propagation products and plant parts. The invention also relates to the biological products themselves, produced according to the invention.
    Type: Grant
    Filed: August 6, 2015
    Date of Patent: March 31, 2020
    Assignee: The Texas A & M University System
    Inventors: Shuhua Yuan, Xin Wang
  • Patent number: 10591410
    Abstract: A flexible waveguide structure including a waveguide on a flexible substrate, both having transparent windows in the mid-infrared range, may serve as a photonic chemical sensor for measuring characteristic absorptions of analytes brought in physical contact with the waveguide. Such a sensor may, in accordance with some embodiments, be formed by an aluminum-nitride waveguide on a borosilicate substrate.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: March 17, 2020
    Assignee: The Texas A&M University System
    Inventor: Pao Tai Lin
  • Patent number: 10590431
    Abstract: The present disclosure teaches the generation of drought tolerant plants. The present disclosure enables manipulation of a phenotypic characteristic referred to as “stay-green” to facilitate drought adaptation in plants by recombinant, mutagenic and/or breeding and selection methods. Plant management practice systems to increase crop yield and harvest efficiency in water-limited environments are also taught herein.
    Type: Grant
    Filed: November 16, 2012
    Date of Patent: March 17, 2020
    Assignees: The State of Queensland, The Texas A&M University System, Grains Research and Development Corporation
    Inventors: Andrew Kenneth Borrell, David Robert Jordan, John Mullet, Patricia Klein
  • Patent number: 10584390
    Abstract: The present invention provides quantitative polymerase chain reaction (PCR) methods and kits for diagnosing trichomoniasis.
    Type: Grant
    Filed: August 6, 2015
    Date of Patent: March 10, 2020
    Assignee: THE TEXAS A&M UNIVERSITY SYSTEM
    Inventors: Mangkey A. Bounpheng, Thomas B. Hairgrove, Carly C. Summarell, Megan E. Schroeder
  • Patent number: 10584201
    Abstract: The present disclosure relates to synthesis of porous polymer networks and applications of such materials. The present disclosure relates to a method of fabricating of a porous polymer network comprising: (a) providing: (i) a first reactant comprising a plurality of compounds comprising at least one acetyl group, said plurality of compounds comprising at least one compound type, and (ii) a second reactant comprising an alkylsulfonic acid, and (b) creating a solution of said reactants, (c) casting said solution in a form, and (d) treating said solution under such conditions so as to produce a porous polymer network.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: March 10, 2020
    Assignee: The Texas A&M University System
    Inventors: Lei Fang, Zi-Hao Guo, Chenxu Wang, Qiang Zhang, Hong-Cai Zhou
  • Publication number: 20200071550
    Abstract: A biodegradable and biocompatible three dimensional construct comprising a combination of a nano silicate (e.g., laponite) and two different polymers, the two polymers each individually providing at least one covalently linked polymer chain and at least one ionically linked polymer chain, the polymeric chains forming a dual strengthening intertwined polymeric system. The constructs demonstrate improved mechanical and strength properties, while the bioinks provide a material having superior printability characteristics suitable for printing a three dimensional biodegradable construct having an aspect ratio of greater than 2.0. The bioink may also comprise cells or combinations of cells. Methods of using the constructs and bioinks for wound healing preparations and tissue regeneration are also provided.
    Type: Application
    Filed: March 13, 2018
    Publication date: March 5, 2020
    Applicant: The Texas A&M University System
    Inventors: Akhilesh K. GAHARWAR, David CHIMENE
  • Patent number: 10577357
    Abstract: Compounds that disrupt the interaction between PCSK9 and LDLR, compositions that include the compounds, and methods for making and using the compounds and compositions.
    Type: Grant
    Filed: September 19, 2017
    Date of Patent: March 3, 2020
    Assignee: The Texas A&M University System
    Inventor: Kevin Burgess
  • Patent number: 10577399
    Abstract: The subject invention pertains to a modified lantibiotic containing an intact cysteine at the C-terminus, particularly, a cysteine that is not decarboxylated and that contains a free carboxyl group. Derivatives of the modified lantibiotic comprising a moiety conjugated to the carboxyl group of the terminal cysteine are also provided. A bacterium that produces a modified lantibiotic having an intact cysteine at the C-terminus are also provided, wherein the bacterium is genetically modified to inactivate a gene that encodes a decarboxylase enzyme that decarboxylates the cysteine at the C-terminus of a precursor lantibiotic. Methods of producing a modified lantibiotic having an intact cysteine at the C-terminus by culturing a bacterium that synthesizes the modified lantibiotic and purifying the lantibiotic are also provided. Mutants of lantibiotics, particularly, mutacin 1140 having higher anti-bacterial activity or higher bacterial expression compared to mutacin 1140 are also provided.
    Type: Grant
    Filed: October 30, 2017
    Date of Patent: March 3, 2020
    Assignee: THE TEXAS A&M UNIVERSITY SYSTEM
    Inventors: James L. Smith, Jerome Escano
  • Patent number: 10561765
    Abstract: An embodiment includes a system comprising: a substrate of a medical device; an un-foamed polyurethane coating directly contacting the substrate and fixedly attached to the substrate; a thermoset polyurethane shape memory polymer (SMP) foam, having first and second states, which directly contacts the polyurethane coating and fixedly attaches to the polyurethane coating; wherein the polyurethane coating fixedly attaches the SMP foam to the substrate. Other embodiments are described herein.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: February 18, 2020
    Assignee: The Texas A&M University System
    Inventors: Rachael Muschalek, Keith Hearon, Landon D. Nash, Duncan J. Maitland
  • Patent number: 10555737
    Abstract: A device for a tissue channel includes a device frame, a shape memory polymer foam segment coupled to the device frame, and an attachment structure coupled to the device frame. The device frame includes a proximal structure, a distal structure, and an intermediate structure coupled to the proximal structure and the distal structure. The proximal structure is configured to collapse to fit into a delivery structure and expand to block migration of the proximal structure. The distal structure is configured to collapse to fit into the delivery structure and expand to block migration of the distal structure. The intermediate structure is configured to fit in the tissue channel upon device deployment. The shape memory polymer foam segment is configured to compress to fit into the delivery structure and occlude the channel. The attachment structure is configured to attach and detach the device from a delivery guide.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: February 11, 2020
    Assignee: The Texas A&M University System
    Inventors: Mark A. Wierzbicki, Duncan Maitland, Matthew W. Miller, Andrea D. Muschenborn, Landon Nash, Jason M. Szafron, Todd Landsman
  • Publication number: 20200040921
    Abstract: In an embodiment, the present disclosure pertains to a cavitation generation device that includes a dactyl plunger rotatable about an axis between an open position and a closed position and a propus socket having a channel. The propus socket is rigidly mounted below the dactyl plunger, and the dactyl plunger is received into the propus socket when the dactyl plunger is in the closed position. The cavitation generation device can also include a torsion spring that biases the dactyl plunger into contact with the propus socket. In another embodiment, the present disclosure pertains to a method of inducing a cavitation including biasing a dactyl plunger via a torsion spring, and rotating the dactyl plunger, by action of the torsion spring, into a propus socket. The propus socket includes a nozzle-shaped channel. The method further includes ejecting a socket cavity volume through the nozzle-shaped channel thereby inducing a cavitation event.
    Type: Application
    Filed: July 18, 2019
    Publication date: February 6, 2020
    Applicant: The Texas A&M University System
    Inventors: David Staack, Xin Tang
  • Publication number: 20200031948
    Abstract: The present disclosure includes a fusion protein, called a “Seldeg”, including a targeting component that specifically binds to a cell surface receptor or other cell surface molecule at near-neutral pH, and an antigen component fused directly or indirectly to the targeting component. The antigen component is configured to specifically bind a target antigen-specific antibody. The present disclosure also includes a method of depleting a target antigen-specific antibody from a patient by administering to the patient a Seldeg having an antigen component configured to specifically bind the target antigen-specific antibody.
    Type: Application
    Filed: December 1, 2017
    Publication date: January 30, 2020
    Applicant: THE TEXAS A&M UNIVERSITY SYSTEM
    Inventors: Elizabeth Sally Ward OBER, Venkata Siva Charan DEVANABOYINA, Raimund Johannes OBER
  • Patent number: 10543200
    Abstract: Compositions and methods for inhibiting and/or sensitizing or re-sensitizing a parasite to an antiparasitic drug are provided. The compositions can comprise a an arylphenoxypropionate derivative, an aryloxyphenoxyacetate derivative, an aryloxyphenylacetate derivative, one or more substituted quinols, or a pharmaceutically acceptable salt, hydrate, or prodrug thereof, or a combination thereof in an amount and formulation sufficient to sensitize the parasite to the drug, treating infection of a patient by a parasite with a drug, or to prevent symptomatic infection of a patient by a parasite with a drug.
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: January 28, 2020
    Assignee: The Texas A&M University System
    Inventors: Manchi C M Reddy, James C. Sacchettini, Nian E. Zhou, Billy F. McCutchen
  • Patent number: 10537628
    Abstract: The present disclosure provides a recombinant viral vector comprising at least one transgene inserted into a Marek's disease viral genome for treatment of diseases in poultry. Also provided are immunogenic compositions comprising such recombinant viral vectors and methods for preventing or inhibiting Marek's disease in combination with at least a second disease in poultry.
    Type: Grant
    Filed: August 4, 2016
    Date of Patent: January 21, 2020
    Assignee: The Texas A&M University System
    Inventors: Sanjay M. Reddy, Blanca M. Lupiani
  • Patent number: 10535262
    Abstract: A system includes a transmitter coupled to a vehicle and a client system. The transmitter broadcasts a wireless signal. The client system includes a receiver that receives the wireless signal from the transmitter. The client system determines an identifier within the wireless signal, compares the identifier within the wireless signal to a list of identifiers, and in response to determining that the identifier within the wireless signal matches a particular identifier within the list of identifiers, generates an alert that the vehicle is approaching.
    Type: Grant
    Filed: April 19, 2018
    Date of Patent: January 14, 2020
    Assignees: The Texas A&M University System, Metropolitan Transit Authority of Harris County, Texas
    Inventors: Anthony P. Voigt, Michael J. Vickich, Micah D. Montoya, Terence H. Fontaine, Lauren K. Cochran
  • Publication number: 20200010343
    Abstract: Methods for reducing the concentration of one or more contaminants in water using zero-valent iron media. In the method, a mixed aluminum (III) and iron (II) salt solution is added to water containing one or more contaminants that is in contact with a zero-valent iron media that comprises (a) a reactive solid comprising zero-valent iron and one or more iron oxide minerals in contact therewith and (b) magnetite to provide an aqueous reaction medium. The aqueous reaction medium is contacted with the zero-valent iron media for a period of time sufficient to reduce the concentration of one or more of the contaminants.
    Type: Application
    Filed: March 12, 2018
    Publication date: January 9, 2020
    Applicant: The Texas A&M University System
    Inventor: Yongheng Huang
  • Patent number: PP31464
    Abstract: The new and distinct zoysiagrass variety described herein is a Z. matrella x Z. japonica F1 hybrid named ‘KSUZ 0802’. ‘KSUZ 0802’ can be distinguished by its superior turf quality, fine-textured leaves, increased resistance to bluegrass billbug (Sphenophorus parvulus Ghyllenhaal), and cold tolerance that is comparable to zoysiagrass varieties adapted to the transition zone growing region in the U.S.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: February 18, 2020
    Assignees: The Texas A&M University System, Kansas State University Research Foundation
    Inventors: Ambika Chandra, Milton C. Engelke, Anthony D. Genovesi, Jack Fry