Abstract: Methods and systems for generating a fracturability index for use in identifying fracture locations and propagation in subterranean formations. A well path can be divided into a plurality of segments and the order of fracture locations along the path can be identified. Such an order is based on an optimal fracture stage from a production point of view followed by subsequent fracture stages. The above steps or operations can be repeated with respect to additional paths to generate data for use in determining prioritized segments and identifying fracture locations and propagation in subterranean formations. Such data can be compiled in the context of a fracturability index map.

Abstract: The present invention includes siRNAs and antibodies that block the interaction between TEM8 and/or CMG2 cell surface proteins and anthrax toxin and methods of treating anthrax exposure with the same.

Abstract: An SP-141 compound is a novel small molecule that can serve as a molecular-targeted chemotherapeutic agent. In one embodiment, the labeled compound can comprise SP-141, which comprises 6-methoxy-1-(naphthalen-1-yl)-9 H-pyrido[3,4-b]indote. The compound inhibits expression of oncogenes such as the Mouse Double Minute 2 protein. The compound can bind directly to Mouse Double Minute 2 to inhibit cancer growth including breast cancer growth.

Abstract: The present invention includes compositions and methods for inhibiting MCL-1, including novel inhibitors of MCL-1, and compositions and methods for treating a subject with cancer that is refractory to one or more MAPK pathway protein inhibitors.

Abstract: A system, method, and apparatus for simulating the detection of radiation comprise at least one simulated radioactive source, a simulated radiation detector, and an emulating module configured to simulate a detection level for the at least one simulated radioactive source according to a radiation level associated with the simulated radioactive source, wherein the simulated detection level is provided on the simulated radiation detector.

Abstract: Devices, methods and systems for wave and water level measurement using a single DC (direct current)-coupled CW (continuous wave) Doppler radar for detecting water elevation changes in time when installed up to several meters from the water surface. The radar is wireless and can stream continuous data to a local PC (personal computer) or base station in range of its radio. The radar can sample up to 40 Hz and can run on batteries for continuous sampling. The radars can include multiple radar configurations of 1, 2 and 4 radar configurations. Applications for this radar can include the measurement of beach run-up, free surface elevation in tidal zones, and storm surge elevations near bridges and critical infrastructure during storm events.

Abstract: The present invention provides a method of hydraulically fracturing a well penetrating an subterranean formation by optimizing the spacing of fractures along a wellbore to form a complex network of hydraulically connected fractures by identifying a deviated wellbore in a subterranean formation; introducing a series of fractures in the deviated wellbore, wherein the series of fractures comprising at least a first fracture, a second fracture, a third fracture and a fourth fracture each separated by a non-uniformed and an increased spacing distance such that the spacing distance from each adjacent fracture in the series of fractures is at an increased distance; and forming one or more complex fractures extending from the series of fractures to form a complex fracture network.

Abstract: Disclosed is a system and method for a hybrid radar system that integrates frequency-modulated continuous wave (FMCW) mode and interferometry mode. The radar works as a time division system that continuously switches between the FMCW mode and interferometry mode. The FMCW mode is responsible for absolute range detection and the interferometry mode takes cares of the weak physiological movement monitoring. The respective accuracies in range detection and displacement measurement complements the advantages of the two radar modes, providing versatile performance. By steering the antenna beam, the proposed radar system becomes an ideal solution for indoor health care, human localization, and human-computer interaction. Objects or human targets with or without stationary clutters can be precisely located. At the same time, the targets' vital signs and gestures can be monitored.

Abstract: Disclosed is an invention of cotton lines 2-340/1-1422, 1-1422/SCM 3-7-3, 1-1422/2-340, 1-136/2-340, AFIS 1-1422. AFIS 2-340, AFIS 1-136, and SCM 3-7-3, and relates to seeds, plants, plant cells, plant tissue and harvested products, lint, and oil, as well as to hybrid cotton plants and seeds and other plants, cultivars, and varieties produced by essentially deriving such plants, cultivars, and varieties from cotton lines 2-340/1-1422, 1-1422/SCM 3-7-3, 1-1422/2-340, 1-136/2-340, AFIS 1-1422, AFIS 2-340, AFIS 1-136, and SCM 3-7-3. The present invention particularly relates to the development of specific cotton lines for the regulation of palmitic acid for the production of seeds having cottonseed oil content with reduced levels of palmitic acid. The cotton lines of the present disclosure have lower levels of palmitic acid content, and allows for the germination of seed at lower soil temperatures than current commercially available cotton cultivars.

Abstract: The present invention includes compositions and methods for eliminating or reducing microbial contamination in lymph nodes that enter the food supply from livestock comprising: identifying an animal in need of eliminating or reducing microbial contamination in non-gut associated lymph nodes that enter the food supply, and providing the animal with an effective amount of a lactic acid bacteria or probiotic bacterial sufficient to reduce or eliminate the microbial contamination in non-gut associated lymph nodes.

Abstract: A electromagnetic wave-induced heating of CNT filled (or coated) polymer composites for enhancing inter-bead diffusive bonding of fused filament fabricated parts. The technique incorporates electromagnetic wave absorbing nanomaterials (carbon nanotubes (CNTs)) onto the surface or throughout the volume of 3D printer polymer filament to increase the inter-bead bond strength following a post electromagnetic wave irradiation treatment and/or in-situ focused electromagnetic beam during printing. The overall strength of the final 3D printed part will be dramatically increased and the isotropic mechanical properties of fused filament part will approach or exceed conventionally manufactured counterparts.

Abstract: Diagnostic tool for eye disease detection using a smartphone. At least some of the example embodiments are methods including capturing, by way of a camera lens on a device, an image of an eye to create a raw specimen; processing the raw specimen to create a processes specimen; performing edge detection on the processed specimen to detect a boundary of a cornea; extracting a region of interest of the cornea; identifying a boundary of the region of interest using a boundary tracing technique to identify a second boundary; analyzing the second boundary of the region of interest, by measuring a slope of the second boundary; and classifying the region of interest as including an eye disease, based on the analyzing the second boundary.

Abstract: The present invention provides a method for treating, alleviating, reversing or delaying progression of at least one symptom of Parkinson's Disease in a subject in need thereof by administering to the subject an effective amount of a 2-amino-2[2-(4-octylphenyl)ethyl]propane-1,3-diol composition or a derivative thereof to treat at least one symptom of Parkinson's Disease.

Abstract: Methods and systems for imaging a magnetic field as vectors (or scalars if desired) in either two or three dimensions without the need for rastering or relative motion between the sensors and the magnetic field being viewed. A secondary function is to image electric current flow as vectors. Example embodiments can be scaled to fit both large and small applications by using discreet devices or manufacturing with MEMS technologies.

Abstract: The present invention includes antigenic fusion proteins, nucleic acids encoding the fusion proteins and methods of making and using the same, wherein the fusion protein comprises three or more different influenza A ectodomains of Matrix Protein 2 (M2e); one or more stem regions of an influenza A hemagglutinin 2 (HA2) protein; and optionally an anthrax antigen, wherein the fusion protein is immunogenic across strains.

Abstract: An apparatus and computerized method optimizes or generates a sigma profile for a molecule by receiving a sigma profile for the molecule, calculating an activity coefficient for the molecule using the sigma profile for the molecule, calculating a solubility for the molecule using the activity coefficient for the molecule, optimizing or adjusting the sigma profile for the molecule by adjusting the sigma profile using an objective function and one or more constraints, providing the sigma profile to an output device communicably coupled to a processor.

Abstract: An apparatus and method of separation of LOX and other commercially valuable components, such as LAr from liquefied air, which consists primarily of LN2. Strong magnetic field gradient and gravity are used to separate LOX from liquefied air, based upon the different magnetic properties of LOX and LN2. The apparatus and method employ a magnetic field gradient to levitate the LN2 and LAr diamagnetic components of liquid air while accelerating the paramagnetic LOX component toward the bottom to achieve oxygen separation. In other embodiments, a leak valve system can be used.

Abstract: The present invention includes composition and methods for a core matrix comprising a dissolved cellulose fiber of, e.g., high molecular weight (DP>5000) or microcrystalline cellulose of low molecular weight (DP: 150-300), printed into a two or three dimensional pattern; a conductive material comprising a carbon nanotube or graphene oxide disposed on or about the cellulose fiber or microcrystalline cellulose; and an enhancer or stabilizer that stabilizes the dissolved cellulose or microcrystalline cellulose disrupted during a printing process, wherein the conductive material and the cellulose or microcrystalline cellulose forms one or more features in or on the cellulose fiber or microcrystalline cellulose.

Abstract: Disclosed is a system and method for a 24-GHz phased array for indoor smart radar comprising at least 6 horizontally placed antenna elements as a vertically placed 5-element series-fed microstrip patch array. The beam of the phased array can be continuously steered on the H-plane to different directions through a novel vector control array. Each element can adjust the phase and amplitude of the corresponding element of the horizontally placed linear array. The phased array system of the present invention may be fabricated on a single printed circuit board (PCB), and PIN diodes are used to realize beam steering by modulating the decomposed received signal. In order to compensate for the loss of the vector control array and reduce the noise figure, six low noise amplifiers (LNAs) are also used in the array. The present invention has the ability to continuously steer the beam on the H-plane.

Abstract: The present invention includes an isolated antigen against influenza A and a method of making the same that includes an ectodomain of influenza A Matrix Protein 2 (M2e) and a stem region of an influenza A hemagglutinin 2 (HA2) protein and an adjuvant. The invention further includes formulating the antigen into an isolated immune response stimulating fusion protein and/or a vaccine.