Patents Assigned to The Board of Regents of the University of Oklahoma
  • Patent number: 9611281
    Abstract: Derivatives of BODIPY (boron dipyrromethene difluoride) and their synthesis and use are disclosed.
    Type: Grant
    Filed: December 5, 2014
    Date of Patent: April 4, 2017
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Youngjae You, Samuel Awuah, Ryan Watley
  • Patent number: 9603896
    Abstract: Peptide compounds based on the CAP37 protein are disclosed, along with methods for treating various infections, wounds, and conditions, and methods of promoting healing and acceptance of grafts, using compositions containing these peptides.
    Type: Grant
    Filed: December 3, 2013
    Date of Patent: March 28, 2017
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Heloise Anne Pereira, Anne Kasus-Jacobi, Gina L. Griffith
  • Patent number: 9603945
    Abstract: Compositions, methods, and systems are disclosed for the development and use of heparosan, a natural polymer related to heparin, as a new therapeutic modifying agent or vehicle which can modulate drug cargo pharmacokinetics and behavior within a mammalian patient.
    Type: Grant
    Filed: December 14, 2012
    Date of Patent: March 28, 2017
    Assignee: The Board of Regents of the University of Oklahoma
    Inventor: Paul L. DeAngelis
  • Patent number: 9601327
    Abstract: A high power electronic device package constructed to include a high power electronic device having an epitaxial surface attached to a thermally conductive submount by a thermally conductive interface layer having a eutectic metal contact therein. A gallium nitride high electron mobility transistor (GaN HEMT) having a transistor structure formed of a GaN thin film layer bonded to a thermally conductive host substrate via a thermally conductive interface layer disposed therebetween, and a method of forming the GaN HEMT. The GaN HEMTs can be used in such applications as, for example, power amplifiers with x-band radio frequency (RF) power outputs for micro-radar applications.
    Type: Grant
    Filed: August 17, 2015
    Date of Patent: March 21, 2017
    Assignee: The Board of Regents of the University of Oklahoma
    Inventor: Patrick J. McCann
  • Patent number: 9595428
    Abstract: A sampling probe, system and analysis method is disclosed. The sampling probe includes a tube having at least a first bore, a second bore, a first end, and a tapered second end; a first capillary partially disposed within the first bore, at least a portion of the first capillary extending from the first end of the tube; a second capillary partially disposed within the second bore, the second capillary having a portion with a free tapered end which extends from the first end of the tube; and wherein an end of the first capillary and an end of the second capillary converge at a junction in the tapered second end of the tube.
    Type: Grant
    Filed: June 17, 2015
    Date of Patent: March 14, 2017
    Assignee: The Board of Regents of the University Oklahoma
    Inventors: Zhibo Yang, Qiang Liu, Ning Pan
  • Patent number: 9550144
    Abstract: A method of treating natural gas to remove contaminants is described. An input natural gas is mixed with water causing formation of CO2 hydrates and CH4 hydrates. A natural gas having a reduced CO2 concentration, and a water-hydrate mixture comprising the CO2 hydrates and CH4 hydrates, is output. The water-hydrate mixture is exposed to CO2 gas forming a CO2—CH4 gas mixture and a residual hydrate mixture. The CO2—CH4 gas mixture is recycled to remove CH4. The residual hydrate mixture is treated to produce H2O which can be recycled for use in forming the water-hydrate mixture, and gaseous CO2 for use in use in stripping CH4 from the CH4 hydrates of the water-hydrate mixture.
    Type: Grant
    Filed: January 27, 2016
    Date of Patent: January 24, 2017
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Miguel Bagajewicz, Quang Nguyen, Tu Oanh Tran, Conner Cruson
  • Publication number: 20170007589
    Abstract: Compositions for use in methods of treating and/or inhibiting a pathologic ocular condition, as well as methods of producing and using same, are disclosed.
    Type: Application
    Filed: February 5, 2015
    Publication date: January 12, 2017
    Applicant: The Board of Regents of the University of Oklahoma
    Inventors: Xi-Qin Ding, Hongwei MA
  • Patent number: 9540337
    Abstract: Compositions that are effective in inhibiting gamma-glutamyl transpeptidase are disclosed. Methods of producing and using these compositions are also disclosed.
    Type: Grant
    Filed: August 23, 2013
    Date of Patent: January 10, 2017
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Marie H. Hanigan, Pui Kai Li
  • Publication number: 20170002295
    Abstract: Sulfur-containing compounds comprising hydrophobic ester moieties and carboxylate moieties, wherein the compounds have surfactant properties, compositions comprising the compounds, and methods of using the compounds or compositions for cleaning purposes.
    Type: Application
    Filed: June 29, 2016
    Publication date: January 5, 2017
    Applicant: Board of Regents of the University of Oklahoma
    Inventors: Graciela B. Arhancet, Scott A. Long, Brian Grady, Jeff Harwell, Guangzhe Yu
  • Patent number: 9527884
    Abstract: The presently disclosed and claimed inventive concepts include inhibitors of antiplasmin cleaving enzyme (APCE) and fibroblast activation protein alpha (FAP) which can be used in various therapies related to disorders of fibrin and ?2-antiplasmin and abnormal cell proliferation. The presently disclosed and claimed inventive concepts also include substrates of APCE and FAP, which may be used, for example, in screening methods for identifying such inhibitors. The presently disclosed and claimed inventive concepts further include, but are not limited to, methods of treating or inhibiting atherosclerosis and thrombus disorders by altering the ratios of types of plasma ?2-antiplasmin and to methods of treating conditions involving abnormal cell proliferation such as cancers.
    Type: Grant
    Filed: January 8, 2015
    Date of Patent: December 27, 2016
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Patrick A. McKee, Kenneth W. Jackson, Kyung N. Lee, Victoria J. Christiansen
  • Patent number: 9504745
    Abstract: Compositions for detecting and/or destroying cancer tumors and/or cancer cells via photodynamic therapy are disclosed, as well as methods of use thereof. The compositions comprise a linking protein or peptide attached to or otherwise physically associated with a carbon nanotube to form a targeted protein-carbon nanotube complex.
    Type: Grant
    Filed: December 9, 2013
    Date of Patent: November 29, 2016
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Roger G. Harrison, Jr., Daniel E. Resasco, Luis Filipe Ferreira Neves
  • Publication number: 20160315578
    Abstract: Novel materials, material deposition methods, and devices used to generate electrical power from thermal radiators based on thermophotovoltatic (TPV) operating principles using group IV-VI alloys and materials are disclosed. A semiconductor structure comprising (N) stacked junctions, each junction formed of a IV-VI semiconductor alloy and each of said N junctions having a bandgap, where N is an integer and N>1 is disclosed. The semiconductor structure is configured to capture electromagnetic radiation having wavelengths from about 1 ?m to about 7 ?m. TPV devices comprising the novel semiconductor structure and methods of making the novel structures and devices are also disclosed.
    Type: Application
    Filed: December 2, 2014
    Publication date: October 27, 2016
    Applicant: The Board of Regents of the University of Oklahoma
    Inventor: Patrick John McCann
  • Patent number: 9453940
    Abstract: The presently disclosed inventive concepts are directed, in at least one non-limiting embodiment, to a computer system and method for issuing a tornado-indicative notification, such as a warning. In one embodiment the method includes receiving time sequential radar reflectivity data from an area undergoing a weather event, via at least one computer port and at least one processor executing processor executable code, analyzing the radar reflectivity data of the area to determine if an entropic source and an entropic sink are present in the area, determining a distance between the entropic source and the entropic sink when the entropic source and the entropic sink are present in the area, and outputting a tornado-indicative notification for the area when the distance between the entropic source and the entropic sink is less than or equal to a predetermined distance.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: September 27, 2016
    Assignee: The Board of Regents of the University of Oklahoma
    Inventor: Yoshi K. Sasaki
  • Patent number: 9417315
    Abstract: A transmitter front end circuit is described. The transmitter front end circuit is provided with a radar transmitter port, a radar receiver port, a radar amplifier, a coupler, a radar antenna input and a signal director. The radar amplifier has a low power side receiving a transmit signal having a transmit waveform modulated onto a carrier frequency from the radar transmitter port, and a high power side outputting an amplified transmit waveform suitable for transmission to a radar antenna. The coupler is coupled to the high power side of the radar amplifier to sample the amplified transmit waveform. The radar antenna input is configured to receive return signals from a radar antenna. And, the signal director selectively directs the sample of the amplified transmit waveform and the return signals to the radar receiver port.
    Type: Grant
    Filed: December 20, 2013
    Date of Patent: August 16, 2016
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Robert Dean Palmer, Redmond Clay Kelley, Boon Leng Cheong, Yan Zhang
  • Patent number: 9399675
    Abstract: Compositions comprising monoclonal antibodies raised against CAP37 (Cationic Antimicrobial Protein of Mr 37 kDa) and isoforms thereof, along with antigen binding fragments thereof, are disclosed. The antibodies are used in the diagnosis and early detection of Alzheimer's disease and Age-Related Macular Degeneration.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: July 26, 2016
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Heloise Anne Pereira, Melva L. Gonzalez
  • Patent number: 9393306
    Abstract: Activatable compositions that include at least one functional moiety and at least one cleavable linker directly or indirectly linked to the at least one functional moiety are disclosed. The at least one functional moiety is inactive when linked to the linker and activated upon cleavage of the linker. Methods of production and use of the activatable composition are also disclosed.
    Type: Grant
    Filed: April 24, 2013
    Date of Patent: July 19, 2016
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Youngjae You, Moses Bio, Abugafar Hossion, Gregory Nkepang
  • Patent number: 9359196
    Abstract: Antiproliferative compositions that include CLEFMA, as well as liposomal compositions containing said antiproliferative compositions, are disclosed. Also disclosed are methods of making and using the antiproliferative compositions and liposomal compositions.
    Type: Grant
    Filed: October 24, 2011
    Date of Patent: June 7, 2016
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Vibhudutta Awasthi, Pallavi Lagisetty, Hrushikesh Agashe
  • Patent number: 9361877
    Abstract: An ultrasonic communication system comprising an enclosure, a first module and a second module is described. The enclosure has an internal surface, an external surface, and defines at least one metal channel. The first module comprises an ultrasonic transceiver disposed within the enclosure. The first module is positioned on the internal surface of the enclosure and is capable of transmitting and/or receiving modulated ultrasonic waves via the metal channel. The second module is positioned on the external surface of the enclosure and is adapted to transmit and/or receive modulated ultrasonic waves from the first module via the metal channel.
    Type: Grant
    Filed: October 30, 2012
    Date of Patent: June 7, 2016
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: John K. Antonio, Mark B. Yeary, Thomas D. Hosman
  • Patent number: 9337617
    Abstract: A tunable semiconductor laser having, in one embodiment, a higher bias voltage end, a lower bias voltage end, and an optically active gain region comprising a band-gap configured to emit light at an emission wavelength that is tunable when an electric field is generated across the optically active gain region by applying a bias voltage thereto, an electron quantum well (QW) layer positioned closer to the higher bias voltage end than the lower voltage bias end, and a hole QW layer positioned closer to the lower bias voltage end than the higher bias voltage end and comprising a type-II band alignment with the electron QW layer such that the band-gap is determined by an energy difference between a ground electron state in the electron QW layer and a ground hole state in the hole QW layer, wherein the emission wavelength is redshifted upon an increase in a bias voltage applied to the optically active gain region.
    Type: Grant
    Filed: February 24, 2015
    Date of Patent: May 10, 2016
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Rui Q. Yang, Zhaobing Tian, Lu Li, Michael B. Santos, Matthew B. Johnson, Yuchao Jiang
  • Patent number: 9303087
    Abstract: Monoclonal antibodies against LRP6 and that block the Wnt signaling pathway are disclosed. Methods of production and use thereof are also disclosed.
    Type: Grant
    Filed: June 9, 2014
    Date of Patent: April 5, 2016
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Jian-xing Ma, Kyungwon Lee, Ying Chen