Abstract: Disclosed is a new compound that inhibits binding between a DX2 protein and a p14/ARF protein, a pharmaceutical composition including the new compound as an effective component for treating or preventing a cancer disease, an anticancer adjuvant for improving an anticancer effect of a drug-resistant anticancer drug, and a composition including an AIMP2-DX2 protein or a fragment thereof for diagnosing lung cancer.

Abstract: The present invention relates to a replication retrovirus vector system comprising thymidine kinase (HSV-TK) gene and cytosine deaminase (CD) gene which make gene transfer to cancer cell tissue for the efficient treatment of cancer. Particularly, the HSV-TK/CD combined self-replicating retrovirus vector system of the present invention characteristically contains both HSV-TK and CD genes; has no worries about losing a therapeutic gene because recombination does not occur in this system during virus infection; and has an excellent stability, and also is able to induce cancer cell death by using the prodrug GCV or 5-FC and can apply a therapeutic gene or a prodrug thereof selectively to such cancer that shows resistance against cancer treatment using either TK or CD, so that this system of the invention can be advantageously used as a pharmaceutical composition for the treatment of cancer.

Abstract: The present invention relates to an repebody capable of binding specifically to interleukin-6 (IL-6) to inhibit the biological activity of IL-6, a polynucleotide encoding the repebody, a vector comprising the polynucleotide, a recombinant microorganism having introduced therein the polynucleotide or the vector, a method of producing the repebody using the recombinant microorganism, a composition for preventing or treating cancer, which comprises the repebody, and a method for preventing or treating cancer, which comprises administering the composition for preventing or treating cancer, which comprises the repebody. The repebody of the present invention significantly reduces the activity of signal transduction and activator of transciption3 (STAT3) and the concentration of interleukin-6, and thus can be widely used as an agent for preventing or treating IL-6-related diseases.

Abstract: The present invention relates to an antimicrobial glass having both electromagnetic shielding and antimicrobial characteristics while maintaining the transparency of glass, and more particularly to an optically transmissive antimicrobial glass with an electromagnetic shielding effect that includes an AZO/Ag/AZO multilayer thin film deposited on a glass substrate.

Abstract: A pharmaceutical composition comprises a Quisaqualis indica extract as an active ingredient, for preventing or treating prostatic hyperplasia, and may also be used in a food composition. The Quisaqualis indica extract may be used to treat and prevent prostatic hyperplasia by exhibiting effects of a reduction in prostate weight, a reduction in DHT as a prostatic hyperplasia inducing factor, and a reduction in prostate epithelial cell hyperplasia.

Abstract: The present invention relates to a replication retrovirus vector system comprising thymidine kinase (HSV-TK) gene and cytosine deaminase (CD) gene which make gene transfer to cancer cell tissue for the efficient treatment of cancer. Particularly, the HSV-TK/CD combined self-replicating retrovirus vector system of the present invention characteristically contains both HSV-TK and CD genes; has no worries about losing a therapeutic gene because recombination does not occur in this system during virus infection; and has an excellent stability, and also is able to induce cancer cell death by using the prodrug GCV or 5-FC and can apply a therapeutic gene or a prodrug thereof selectively to such cancer that shows resistance against cancer treatment using either TK or CD, so that this system of the invention can be advantageously used as a pharmaceutical composition for the treatment of cancer.

Abstract: Disclosed is a method for reducing contact resistance, including depositing a GST layer on an InGaAs substrate, generating an InGaAs/GST/Ni stacked structure by depositing a Ni layer on the GST layer, and thermally treating the stacked structure to rearrange components of the GST layer and to generate a Ni—InGaAs alloy.

Abstract: A bio impedance measurement apparatus includes a current applicator configured to provide, to terminals contacting a body, a current based on a first control signal, and a modulator configured to modulate a voltage generated as the current flows through the body, based on a second control signal. The apparatus further includes an amplifier configured to amplify the modulated voltage, and a demodulator configured to demodulate the amplified voltage based on a third control signal.

Abstract: An apparatus of processing a signal or a biosignal, and a method of processing a signal or a biosignal are provided. The method of processing signal involves receiving a first reference signal having a frequency component of a measurement signal to be applied to a subject, receiving a second reference signal having a frequency component within a frequency bandwidth of an amplifier, and converting a first signal measured from the subject to a second signal within the frequency bandwidth of the amplifier, based on the first reference signal and the second reference signal.

Abstract: Disclosed is a new compound that inhibits binding between a DX2 protein and a p14/ARF protein, a pharmaceutical composition including the new compound as an effective component for treating or preventing a cancer disease, an anticancer adjuvant for improving an anticancer effect of a drug-resistant anticancer drug, and a composition including an AIMP2-DX2 protein or a fragment thereof for diagnosing lung cancer.

Abstract: A biosignal apparatus is described including an amplifier and a sampler. The amplifier is configured to alternate between an operating state and a low power state based on a periodically changing control signal. The sampler is configured to sample a signal output from the amplifier in response to the amplifier being in the operating state and maintain the sampled signal in response to the amplifier being in the low power state.

Abstract: The present invention relates to a transfer-free method for forming a graphene layer, in which a high-quality graphene layer having excellent crystallinity can be easily formed over a large area at low temperature by a transfer-free process so that it can be applied directly to a base substrate, which is used in a transparent electrode, a semiconductor device or the like, without requiring a separate transfer process, and to an electrical device comprising a graphene layer formed by the method. More specifically, the transfer-free method for forming a graphene layer comprises the steps of: depositing a Ti layer having a thickness of 3-20 m on a base substrate by sputtering; and growing graphene on the deposited Ti layer by chemical vapor deposition.

Abstract: Provided is a magnetic sensor for detecting a magnetic field. The magnetic sensor includes a magnetic layer of a closed loop shape; a pair of current terminals which face each other contacting with the closed loop and through which current is input/output; and a pair of voltage terminals which face each other contacting with the closed loop and from which output voltage is detected. Both an anisotropic magnetoresistance effect (AME) and a planar Hall effect (PHE) contribute to the output voltage and a hysteresis of the output voltage is eliminated by exchange coupling of a ferromagnetic layer by a ferromagnetic-antiferromagnetic layer structure and a ferromagnetic-metal-antiferromagnetic layer structure. Accordingly, it is possible to minimize a hysteresis due to a demagnetization factor of the closed loop, stabilize the output voltage of the magnetic sensor and enhance sensitivity.

Abstract: A device for transporting, trapping and escaping a single biomaterial using a magnetic structure, and a method of transporting, trapping and escaping of the single biomaterial using the same are provided, and a method is provided for controlling movement and direction of the single biomaterial including soft magnetic micro structure and magnetic structure in a linear, square storage, apartment type, radial soft magnetic micro structure. Accordingly, the device for transporting, trapping and escaping a single biomaterial and the method for transporting, trapping and escaping single biomaterial using the same can control movement on the lap-on-a-chip with increased precision and ease, by using magnetic force, and thus can be advantageously used in the field of magneto-resistive sensor, or categorization of single cells or biomolecules.

Abstract: A signal processing apparatus and a method are disclosed, in which the signal processing apparatus may convert an analog signal to a digital signal and store the digital signal. The signal processing apparatus may convert analog signals, transmitted by multiple analog channels, to digital signals using analog-to-digital converters (ADCs), hold the digital signals for a predetermined holding time, sequentially read the held digital signals for each digital channel, and store the sequentially read digital signals.

Abstract: A signal processing apparatus and a method are disclosed, in which the signal processing apparatus may convert an analog signal to a digital signal and store the digital signal. The signal processing apparatus may convert analog signals, transmitted by multiple analog channels, to digital signals using analog-to-digital converters (ADCs), hold the digital signals for a predetermined holding time, sequentially read the held digital signals for each digital channel, and store the sequentially read digital signals.

Abstract: Disclosed is a method and related system of regenerating a raw material for a hydrogen supply system of a fuel cell. The method includes reacting aluminum and a metal hydroxide to produce hydrogen in the hydrogen supply system of a fuel cell; and recovering an aluminum compound produced simultaneously with the hydrogen in the reaction. An aluminum hydroxide is obtained from the aluminum compound. The aluminum hydroxide is heat-treated to obtain an aluminum oxide. The aluminum oxide is reduced to obtain aluminum. The obtained aluminum is re-supplied as a raw material for producing the hydrogen.

Abstract: Provided is an apparatus for determining an available driving space, including a laser distance sensor installed in a vehicle and configured to sense a region in front of the vehicle by a predetermined distance to generate distance information, a signal processing unit configured to generate plane distance information by using the distance information generated by the laser distance sensor, a curb searching unit configured to determine correlation and similarity between the generated plane distance information and previous plane distance information to search for a curb, and a determining unit configured to determine whether the region in front of the vehicle by the predetermined distance is an available driving space depending on whether a route of a curb searched by the curb searching unit is included in a driving region.

Abstract: Provided is a method and apparatus for low power operation of a binaural hearing aid, the method including determining whether a residual battery exceeds a predetermined threshold level, collecting an external audio signal, in response to whether the residual battery exceeds the predetermined threshold level, and transmitting the collected audio signal to a second hearing aid.

Abstract: A signal processing method and apparatus for measuring heartbeat and oxygen saturation. The signal processing apparatus may acquire a first sampled signal by sampling a detection signal output from an optical detector in an interval in which a light source is activated, may acquire a second sampled signal by sampling a detection signal output from the optical detector in an interval in which the light source is inactivated, and may output a combined signal in which the first sampled signal and the second sampled signal are combined. An amplitude of the first sampled signal may decrease by combining the first sampled signal with the second sampled signal.