Patents Assigned to The National University of Singapore
  • Patent number: 11497145
    Abstract: A server (10), a server rack (50) and a data centre (100, 150) are provided. The server (10) includes a housing (12) defining a gaseous flow passage. A plurality of active components (14) and a plurality of passive components (16) are provided in the housing (12). A plurality of liquid cooling devices (18) is attached to respective ones of the active components (14).
    Type: Grant
    Filed: August 7, 2019
    Date of Patent: November 8, 2022
    Assignee: National University of Singapore
    Inventors: Poh Seng Lee, Yong Jie Chen, Matthew Lee Liong Law, Navin Raja Kuppusamy
  • Publication number: 20220339316
    Abstract: Described is a haemostatic device comprising a substrate and a surface formed on the substrate. The surface comprises at least one of micro- and nano-sized materials, the materials being partially embedded in a base, the surface substantially preventing wetting of the substrate. An embodiment of the device is carbon nano fibres embedded partially in a PDMS or PTFE base, on a substrate.
    Type: Application
    Filed: June 15, 2020
    Publication date: October 27, 2022
    Applicants: National University of Singapore, ETH Zurich
    Inventors: Choon Hwai YAP, Zhe LI, Dimosthenis POULIKAKOS, Athanasios MILIONIS
  • Patent number: 11479719
    Abstract: A nanocrystal scintillator that contains a thin-film layer of perovskite-based quantum dots coated on a substrate layer. The quantum dots each have a formula of CsPbXaY3-a, CH3NH3PbX3, or NH2CH?NH2PbX3, in which each of X and Y, independently, is Cl, Br, or I, and a is 0-3. The substrate layer is an aluminum substrate, a fluoropolymer substrate, a fiber optic plate, a ceramic substrate, or a rubber substrate. Also disclosed are an ionizing radiation detector and an ionizing radiation imaging system containing such a nanocrystal scintillator.
    Type: Grant
    Filed: April 18, 2019
    Date of Patent: October 25, 2022
    Assignee: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Xiaogang Liu, Qiushui Chen
  • Patent number: 11474167
    Abstract: A method for detecting a magnetic field using a spin-orbit torque magnetic field sensor is described. The spin-orbit torque magnetic field sensor comprises a magnetic layer having a switchable magnetic state. The method comprises: (i) providing an alternating current to the sensor for creating an oscillatory spin-orbit torque in the magnetic layer to switch the switchable magnetic state between two magnetic states; and (ii) measuring an output voltage of the sensor, the output voltage being dependent on the magnetic field and is a time average of a time-varying anomalous Hall voltage generated in the magnetic layer in response to the oscillatory spin-orbit torque and the magnetic field.
    Type: Grant
    Filed: August 13, 2021
    Date of Patent: October 18, 2022
    Assignee: National University of Singapore
    Inventors: Yihong Wu, Hang Xie
  • Patent number: 11474601
    Abstract: In a described embodiment, a sensor-based communication apparatus (100) is disclosed. The communication apparatus (100) comprises a plurality of sensor nodes (112) associated with respective unique pulse signatures (200) and adapted to communicate with respective sensors (113) with each sensor (113) configured to generate a sensory signal (113a) in response to a respective stimulus (113b). Each sensor node (112) is triggered, upon receipt of the corresponding sensory signal (113a), to transmit the associated unique pulse signature (200) independently and asynchronously through a transmission medium (110) shared by the sensor nodes (112), and the unique pulse signatures (200) transmitted by the sensor nodes (112) being a representation (300) of a stimulus event associated with the stimuli detected by the corresponding sensors (113). A method and a communication medium are also disclosed.
    Type: Grant
    Filed: December 3, 2018
    Date of Patent: October 18, 2022
    Assignee: National University of Singapore
    Inventors: Chee Keong Tee, Wang Wei Lee, Kian Ann Ng, John Ho
  • Publication number: 20220325089
    Abstract: A dielectric material, to a device comprising the dielectric material and to use of the dielectric material in the fabrication of a device. One dielectric material may comprise a halogen-based elastomer mixed with a halogen based surfactant and exhibiting electro-mechanical self-healing properties and/or an increased dielectric constant compared to the halogen-based elastomer. Another dielectric material may comprise a halogen-based polymer mixed with a halogen based surfactant and exhibiting an increased dielectric constant compared to the halogen-based polymer.
    Type: Application
    Filed: May 31, 2019
    Publication date: October 13, 2022
    Applicant: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Chee Keong TEE, Yu Jun TAN
  • Patent number: 11465100
    Abstract: There is provided a thin film composite (TFC) hollow fibre membrane comprising a porous hollow fibre support layer formed of a polymer and a selective layer, formed of a cross-linked polyamide, on an inner circumferential surface of the hollow fibre support layer, wherein the TFC hollow fibre membrane has a power density of 25-50 W/m2 at a pressure of 30 bar. There is also provided a method of forming the TFC hollow fibre membrane.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: October 11, 2022
    Assignee: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Chunfeng Wan, Tianshi Yang, Wenxiao Gai, Tai-Shung Neal Chung
  • Publication number: 20220322505
    Abstract: There is provided a thermal material comprising an electrode, a film of reduced graphene oxide, a porous membrane that is sandwiched between the electrode and the film of reduced graphene oxide, and an ionic liquid that is disposed within pores of the porous membrane. There is also provided a method of preparing a thermal material. There is further provided a method of changing an article's apparent temperature. There is further provided a device comprising the thermal material as described herein.
    Type: Application
    Filed: March 31, 2022
    Publication date: October 6, 2022
    Applicant: National University of Singapore
    Inventors: Daria Andreeva-Baeumler, Konstantin Novoselov
  • Publication number: 20220306662
    Abstract: Molybdenum(IV) and molybdenum(III) coordination complexes are described. Methods for depositing molybdenum-containing films on a substrate are described. The substrate is exposed to a molybdenum precursor and a reactant to form the molybdenum-containing film (e.g., elemental molybdenum, molybdenum oxide, molybdenum carbide, molybdenum silicide, molybdenum nitride). The exposures can be sequential or simultaneous.
    Type: Application
    Filed: June 16, 2022
    Publication date: September 29, 2022
    Applicants: Applied Materials, Inc., National University of Singapore
    Inventors: Andrea Leoncini, Paul Mehlmann, Nemanja Dordevic, Han Vinh Huynh, Doreen Wei Ying Yong
  • Publication number: 20220298224
    Abstract: An IL-11 binding receptor capable of binding to IL-11 and inhibiting IL-11 mediated signalling is disclosed. Also disclosed are compositions comprising the IL-11 binding receptor and methods using the IL-11 binding receptor.
    Type: Application
    Filed: March 4, 2022
    Publication date: September 22, 2022
    Applicants: National University of Singapore, Singapore Health Services PTE LTD.
    Inventors: Stuart Alexander Cook, Sebastian Schaefer
  • Publication number: 20220299385
    Abstract: A composite structure for a pressure sensor, a pressure sensor, a method of pressure sensing using the pressure sensor, and a method of fabricating a composite structure for a pressure sensor. The method of fabricating a composite structure for a pressure sensor comprises the steps of forming an array of microstructures made from an elastomeric material; and forming a flexible conductive coating on the array of microstructures such that a surface morphology of microstructures is substantially maintained for the coated array of the microstructures; wherein the conductive coating exhibits a Young's modulus that is higher than that of the elastomeric material.
    Type: Application
    Filed: June 10, 2020
    Publication date: September 22, 2022
    Applicant: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Chee Keong TEE, Haicheng YAO, Pengju LI, Wen CHENG
  • Patent number: 11447606
    Abstract: Disclosed herein is a porous polymeric material having a repeating unit according to Formula (I) or (IV), wherein each of A and E has a ? conjugated system and each of X and G contain a flexible tetraphenylethylene (TPE) group. Also disclosed herein are fluorescent chemical sensors or biosensors or environmental monitoring assays or nanosheets or composite materials that include the polymer, and a method of detecting a volatile organic chemical or a metal ion in solution phase.
    Type: Grant
    Filed: March 21, 2018
    Date of Patent: September 20, 2022
    Assignee: National University of Singapore
    Inventors: Dan Zhao, Jinqiao Dong
  • Publication number: 20220293430
    Abstract: Exemplary methods of etching a silicon-containing material may include flowing a fluorine-containing precursor into a remote plasma region of a semiconductor processing chamber. The methods may include forming a plasma within the remote plasma region to generate plasma effluents of the fluorine-containing precursor. The methods may include flowing the plasma effluents into a processing region of the semiconductor processing chamber. A substrate may be positioned within the processing region. The substrate may include a trench formed through stacked layers including alternating layers of silicon nitride and silicon oxide. The methods may include isotropically etching the layers of silicon nitride while substantially maintaining the silicon oxide.
    Type: Application
    Filed: February 1, 2022
    Publication date: September 15, 2022
    Applicants: Applied Materials, Inc., National University of Singapore
    Inventors: Mikhail Korolik, Paul E. Gee, Bhaskar Jyoti Bhuyan, John Sudijono, Wei Ying Doreen Yong, Kah Wee Ang, Samarth Jain
  • Patent number: 11440958
    Abstract: The present invention provides compositions comprising an anti-CD7 chimeric activating receptor (CAR) and an anti-CD7 protein expression blocker, and methods of using such compositions in cancer therapy.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: September 13, 2022
    Assignee: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Yi Tian Png, Natasha Vinanica, Takahiro Kamiya, Dario Campana
  • Publication number: 20220275012
    Abstract: Dinuclear molybdenum coordination complexes are described. Methods for depositing molybdenum-containing films on a substrate are described. The substrate is exposed to a dinuclear molybdenum precursor and a reactant to form the molybdenum-containing film (e.g., elemental molybdenum, molybdenum oxide, molybdenum carbide, molybdenum silicide, molybdenum nitride). The exposures can be sequential or simultaneous.
    Type: Application
    Filed: May 18, 2022
    Publication date: September 1, 2022
    Applicants: Applied Materials, Inc., National University of Singapore
    Inventors: Andrea Leoncini, Paul Mehlmann, Nemanja Dordevic, Han Vinh Huynh, Doreen Wei Ying Yong
  • Publication number: 20220275378
    Abstract: Dumbbell-shaped DNA minimal vectors represent genetic vectors solely composed of the gene expression cassette of interest and terminal closing loop structures. Dumbbell vectors for small hairpin RNA or microRNA expression are extremely small-sized which is advantageous with regard to cellular delivery and nuclear diffusion. Conventional strategies for the generation of small RNA-expressing dumbbell vectors require cloning of a respective plasmid vector which is subsequently used for dumbbell protection. Here, we present a novel cloning-free method for the generation of small RNA-expressing dumbbell vectors which also does not require any restriction endonucleases. The method comprises the PCR amplification of a universal DNA template using primers containing the sense or antisense strand of the sequence of interest, the denaturing and refolding of the amplified product to form stem-loop structures, and the structures are covalently closed using DNA ligases to obtain dumbbell structures.
    Type: Application
    Filed: August 21, 2020
    Publication date: September 1, 2022
    Applicant: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Volker PATZEL, Samantha Leeanne CYRILL
  • Publication number: 20220277763
    Abstract: Disclosed is a system for assessing quality of a singing voice singing a song. The system comprises memory and at least one processor. The memory stores instructions that, when executed by the at least one processor, cause the at least one processor to receive a plurality of inputs comprising a first input and one or more further inputs, each input comprising a recording of a singing voice singing the song, to determine, for the first input, one or more relative measures of quality of the singing voice by comparing the first input to each further input; and to assess quality of the singing voice of the first input based on the one or more relative measures. Also disclosed is a method implemented on such a system.
    Type: Application
    Filed: August 5, 2020
    Publication date: September 1, 2022
    Applicant: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Chitralekha GUPTA, Haizhou LI, Ye WANG
  • Patent number: 11426408
    Abstract: The present invention relates to the use of serotonergic compounds for the treatment of virus-induced thrombocytopenia. More particularly, the invention relates to methods of treating thrombocytopenia by blocking serotonin activity. For example, inhibitors of receptor 5HT2A and/or receptor 5HT1A and/or inhibitors of mast cell degranulation and/or inhibitors of serotonin uptake may be used. Preferably, the thrombocytopenia is induced by dengue or Japanese Encephalitis virus, and the inhibitors are preferably ketanserin, WAY-100135, sarpogrelate, or fluoxetine.
    Type: Grant
    Filed: October 31, 2018
    Date of Patent: August 30, 2022
    Assignee: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Ashley Lauren St. John, Mohamad Fadhli Bin Masri, Abhay Rathore
  • Publication number: 20220267288
    Abstract: The invention concerns a novel cardiac therapeutic effective against atrial fibrillation (AF); a pharmaceutical composition comprising same; the use of same to treat cardiac disease; and a method of treating cardiac disease involving the use of same.
    Type: Application
    Filed: July 8, 2020
    Publication date: August 25, 2022
    Applicant: National University of Singapore
    Inventors: Chun Yong Eric Chan, Aneesh Vidyadhar Karkhanis, Gopalakrishnan Venkatesan
  • Publication number: 20220256819
    Abstract: Four zebrafish gene promoters, which are skin specific, muscle specific, skeletal muscle specific and ubiquitously expressed respectively, were isolated and ligated to the 5? end of the EGFP gene. When the resulting chimeric gene constructs were introduced into zebrafish, the transgenic zebrafish emit green fluorescence under a blue light or ultraviolet light according to the specificity of the promoters used. Thus, new varieties of ornamental fish of different fluorescence patterns, e.g., skin fluorescence, muscle fluorescence, skeletal muscle-specific and/or ubiquitous fluorescence, are developed.
    Type: Application
    Filed: February 25, 2022
    Publication date: August 18, 2022
    Applicant: National University of Singapore
    Inventors: Zhiyuan GONG, Jiangyan HE, Bensheng JU, Toong Jin LAM, Yanfei XU, Tie YAN